Abstract: Systems and methods for providing the progressive download of media content using techniques that preferentially identify and use periods of surplus network capacity to maintain the content delivery. A buffer of a receiving system is maintained and pre-filled with enough content to bridge playback intervals where a network is unable to deliver content as fast as it is played out. When no surplus network capacity is available, a user requesting content may be given the option to continue the delivery in the background so that the content may be played at a later time. The user may then resume their playback experience once the content has been completely delivered using surplus network capacity as it becomes available. A first portion of a content file may be pre-delivered to the receiving system so that users may consume the first portion content while the buffer is pre-filled.

Abstract: Systems and methods for discovering content sources and/or delivering content to applications resident on mobile devices are described. In some embodiments, the systems and methods transmit information identifying one or more applications resident on a mobile device to a server, receive, from the server, information associated with content items available for retrieval from a content server and associated with the identified one or more applications, and cause the mobile device to retrieve at least one of the content items available for retrieval from the content server.

Abstract: Systems and methods for providing the progressive download of media content using techniques that preferentially identify and use periods of surplus network capacity to maintain the content delivery. A buffer of a receiving system is maintained and pre-filled with enough content to bridge playback intervals where a network is unable to deliver content as fast as it is played out. Content delivery does not impact other users' applications and use of the network and its resources since content is only sent when surplus network capacity exists in the network. When no surplus network capacity is available, a user requesting content may be given the option to continue the delivery in the background so that the content may be played at a later time. The user may then resume their playback experience once the content has been completely delivered using surplus network capacity as it becomes available.

Abstract: A method and apparatus for processing at least one information feed are disclosed. For example, the method receives at least one content via at least one automated feed. The method associates the at least one content to one or more geographical locations on a map, wherein the one or more geographical locations are determined from the at least one content. The method then presents an access to the at least one content to a user via the map.

Abstract: The present invention provides for a brokering device adapted to manage multimedia information including an interface device having access to a network and a multimedia service provider. The interface device enables selection of multimedia information from the network and provides the selected multimedia information to a plurality of locations without requiring the user to specify a protocol associated with the multimedia information.

Abstract: Systems and methods for pre-delivering content to user devices are described. In some embodiments, the systems and methods may assign a user device to a group of user devices that receive content from a common network edge cache, identify one or more differences between content delivered to the user device and content delivered to the group of user devices via the common network edge cache, select a piece of content to deliver to the user device based on the identified one or more differences of content, and cause delivery of the selected piece of content to the user device.

Abstract: An adaptive file delivery system and method transmits a data file, such as an audio-video file, over a network or collection of networks in segments in response to a request for the data file by a receiving system. In addition to the requested file, a sending system sends an unrequested secondary data file to the receiving system for playback before, during, or after playing of the requested data file.

Abstract: An adaptive file delivery system and method transmits a data file, such as an audio-video file, over a network or collection of networks in segments, each segment transmitted during a different time period. Each time period has a transmission portion to transmit its associated file segment and a wait portion in which no further interaction with the network occurs regarding the transmitted segment. In some implementations, the duration of the transmission portion of each time period is sufficient to reach a steady-state throughput condition, which allows the traffic load status of the network or networks to be determined from rate measurements of file segment transmissions. The duration of the wait portion of each time period is at least long enough to limit the average rate of file segment transmission to adapt to network traffic load variations while causing the entire file to be delivered in a predetermined delivery deadline.

Abstract: Systems and methods for selecting a delivery policy and/or protocol via which to delivery media and other content from a content provider to a receiving device, is described. In some embodiments, the systems and methods access a request from an application supported by a mobile device to receive a media file from a remote content server, select a delivery policy via which to deliver the media file from the remote content server to the application based on information associated with the media file, and cause the media file to be delivered from the remote content server to the application via the selected delivery policy.

Abstract: Information relevant to internet security is received at a data center server. Such information, for example, a network intrusion alert or details on a recent outbreak of an network virus, may be examined to determine the nature and scope of the security-related information. A security alert is promptly generated in response to the information, using previously stored multimedia content divided into categories of security alerts and/or multimedia content generated at the data center shortly after receiving the security information. The security alert is then disseminated to a plurality of mobile device users. The alerts may be disseminated only to the users associated with a certain security event category, or may be sent to different groups of users depending on other relevant criteria.

Abstract: Systems and methods for providing the progressive download of media content using techniques that preferentially identify and use periods of surplus network capacity to maintain the content delivery. A buffer of a receiving system is maintained and pre-filled with enough content to bridge playback intervals where a network is unable to deliver content as fast as it is played out. Content delivery does not impact other users' applications and use of the network and its resources since content is preferentially sent when surplus network capacity exists in the network. When no surplus network capacity is available, a user requesting content may be given the option to continue the delivery in the background so that the content may be played at a later time. The user may then resume their playback experience once the content has been completely delivered using surplus network capacity as it becomes available.

Abstract: A method and apparatus for processing at least one information feed are disclosed. For example, the method receives at least one content via at least one automated feed. The method associates the at least one content to one or more geographical locations on a map, wherein the one or more geographical locations are determined from the at least one content. The method then presents an access to the at least one content to a user via the map.

Abstract: The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided.

Abstract: An adaptive file delivery system and method transmits a data file, such as an audio-video file, over a network or collection of networks in segments, each segment transmitted during a different time period. Each time period has a transmission portion to transmit its associated file segment and a wait portion in which no further interaction with the network occurs regarding the transmitted segment. In some implementations, the duration of the transmission portion of each time period is sufficient to reach a steady-state throughput condition, which allows the traffic load status of the network or networks to be determined from rate measurements of file segment transmissions. The duration of the wait portion of each time period is at least long enough to limit the average rate of file segment transmission to adapt to network traffic load variations while causing the entire file to be delivered in a predetermined delivery deadline.

Abstract: Sustainable average data throughput rates for data transfer between a sender and a receiver are determined for a network in a steady-state condition. Delivery performance for data transferred in non-steady-state conditions is disregarded in determining sustainable average data throughput rates. The rates may be used to adapt file delivery to network conditions.

Abstract: Methods and systems for content recording and indexing are described. Content may be accessed from a content source. The content may be processed to generate an index of the content. Programming data for future content may be accessed. A content selection guide may be generated in accordance with the index and the programming data. The content selection guide may include a listing of the indexed content and the future content.

Abstract: An adaptive file delivery system and method transmits a data file, such as an audio-video file, over a network or collection of networks in segments, each segment transmitted during a different time period. In one embodiment, data files are transmitted on behalf of a third party using one or more service provider networks. In an exemplary embodiment, the third party contracts with the sending system to transmit the data files using the service provider networks to transmit data files to customers of the respective service provider networks. The data file is transmitted as a plurality of segments and transmitted in such a way so as to prevent congestion in the respective service provider networks.

Abstract: A method and apparatus for processing at least one information feed are disclosed. For example, the method receives at least one content via at least one automated feed. The method associates the at least one content to one or more geographical locations on a map, wherein the one or more geographical locations are determined from the at least one content. The method then presents an access to the at least one content to a user via the map.

Abstract: A repository receives metadata from databases associated with different service providers. The repository converts the received metadata to a common format, such as MPEG7, and stores the converted metadata in a central database. The repository can also receive a query from a client device. The repository retrieves metadata associated with the query from the central database and provides it to the requesting client device. The repository can also convert the provided metadata to an appropriate format for the requesting device. Because the metadata is stored at a common location in a common format, content from different providers can be efficiently identified.

Abstract: The invention provides methods for treating patients which methods comprise methods for predicting responses of cells, such as tumor cells, to treatment with therapeutic agents. These methods involve measuring, in a sample of the cells, levels of one or more components of a cellular network and then computing a Network Activation State (NAS) or a Network Inhibition State (NIS) for the cells using a computational model of the cellular network. The response of the cells to treatment is then predicted124 based on the NAS or NIS value that has been computed. The invention also comprises predictive methods for cellular responsiveness in which computation of a NAS or NIS value for the cells (e.g., tumor cells) is combined with use of a statistical classification algorithm. Biomarkers for predicting responsiveness to treatment with a therapeutic agent that targets a component within the ErbB signaling pathway are also provided.