Patents by Inventor David H. Fine

David H. Fine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conversion of nitrogen dioxide (NO) to nitric oxide (NO)
    Patent number: 8715577
    Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: May 6, 2014
    Assignee: Geno LLC
    Inventors: David H. Fine, David P. Rounbehler, Gregory Vasquez, Bryan Johnson
  • Systems for generating nitric oxide
    Patent number: 8701657
    Abstract: In one aspect, a system for delivering nitric oxide to a patient can include a first gas source including nitrogen dioxide mixed in air or oxygen, a second gas source supplying compressed air, a ventilator coupled to the first and second gas sources, where the ventilator can be resistant to nitrogen dioxide, and where the ventilator provides a gas flow having a proper amount of nitrogen dioxide, one or more conversion devices operably coupled to the ventilator, where the conversion devices covert nitrogen dioxide into nitric oxide, and a patient interface operably coupled to the conversion devices, where the patient interface delivers nitric oxide to the patient.
    Type: Grant
    Filed: August 13, 2009
    Date of Patent: April 22, 2014
    Assignee: Geno LLC
    Inventors: David H. Fine, Gregory Vasquez, Bryan Johnson
  • CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO)
    Publication number: 20140102448
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. A nitric oxide delivery system that converts nitrogen dioxide to nitric oxide employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid.
    Type: Application
    Filed: December 16, 2013
    Publication date: April 17, 2014
    Inventors: David P. Rounbehler, David H. Fine
  • SYSTEMS AND DEVICES FOR GENERATING NITRIC OXIDE
    Publication number: 20140102447
    Abstract: Various systems and devices for generating nitric oxide are disclosed herein. According to one embodiment, the device includes a body having an inlet, an outlet, and a porous solid matrix positioned with the body. The porous solid matrix is coated with an aqueous solution of an antioxidant, wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the solid matrix to convert nitrogen dioxide in the gas flow into nitric oxide. The porous solid matrix allows the device to be used in any orientation. Additionally, the porous solid matrix provides a rigid structure suitable to withstand vibrations and abuse without compromising device functionality.
    Type: Application
    Filed: December 16, 2013
    Publication date: April 17, 2014
    Inventors: David H. Fine, Bryan Johnson, Gregory Vasquez
  • CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO)
    Publication number: 20140102446
    Abstract: Various systems, devices, NO2 absorbents, NO2 scavengers and NO2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.
    Type: Application
    Filed: December 16, 2013
    Publication date: April 17, 2014
    Inventors: David H. Fine, Gregory Vasquez, David P. Rounbehler
  • Nitric oxide delivery system
    Patent number: 8646445
    Abstract: An ambulatory or stationary device for delivery of a therapeutic amount of nitric oxide to an individual's lungs.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: February 11, 2014
    Assignee: Geno LLC
    Inventors: David H. Fine, Gregory Vasquez, Bryan Johnson, Jody Fuller, Ryan Denton
  • Nitric oxide therapies
    Patent number: 8613958
    Abstract: A method for delivering nitric oxide therapy to a subject can include administering a composition including a nitric-oxide releasing agent and silica to the subject and releasing a therapeutic amount of nitric oxide from the composition.
    Type: Grant
    Filed: June 21, 2010
    Date of Patent: December 24, 2013
    Assignee: GENO LLC
    Inventor: David H. Fine
  • Conversion of nitrogen dioxide (NO) to nitric oxide (NO)
    Patent number: 8609028
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. A nitric oxide delivery system that converts nitrogen dioxide to nitric oxide employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: December 17, 2013
    Assignee: Geno LLC
    Inventors: David R. Rounbehler, David H. Fine
  • Systems and devices for generating nitric oxide
    Patent number: 8607785
    Abstract: Various systems and devices for generating nitric oxide are disclosed herein. According to one embodiment, the device includes a body having an inlet, an outlet, and a porous solid matrix positioned with the body. The porous solid matrix is coated with an aqueous solution of an antioxidant, wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the solid matrix to convert nitrogen dioxide in the gas flow into nitric oxide. The porous solid matrix allows the device to be used in any orientation. Additionally, the porous solid matrix provides a rigid structure suitable to withstand vibrations and abuse without compromising device functionality.
    Type: Grant
    Filed: August 13, 2009
    Date of Patent: December 17, 2013
    Assignee: Geno LLC
    Inventors: David H. Fine, Bryan Johnson, Gregory Vasquez
  • CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO)
    Publication number: 20130037023
    Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
    Type: Application
    Filed: August 16, 2012
    Publication date: February 14, 2013
    Inventors: David R. Rounbehler, David H. Fine
  • Method and apparatus for nitric oxide generation
    Patent number: 8371296
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
    Type: Grant
    Filed: May 8, 2006
    Date of Patent: February 12, 2013
    Assignee: Geno, LLC
    Inventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
  • CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO)
    Publication number: 20130017277
    Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. A nitric oxide delivery system that converts nitrogen dioxide to nitric oxide employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid.
    Type: Application
    Filed: July 23, 2012
    Publication date: January 17, 2013
    Inventors: David R. Rounbehler, David H. Fine
  • PRESSURIZED VESSEL OF NITRIC OXIDE (NO)
    Publication number: 20120285449
    Abstract: A pharmaceutical product can include a pressure vessel containing a pressurized gas including at least about 1% nitric oxide.
    Type: Application
    Filed: June 8, 2012
    Publication date: November 15, 2012
    Inventors: David H. Fine, Bryan Johnson
  • Pressure Activated Sampling System
    Publication number: 20120272712
    Abstract: Screening of items for the presence of contaminants, such as explosives residue, is accomplished by subjecting an item loaded into a pressure chamber to a pressure substantially in excess of atmospheric pressure conditions and rapidly decompressing the item to the ambient atmospheric pressure. The rapid decompression serves to scavenge vapors and particles from the exterior and interior of the item and any objects it contains. A sample of the vapors and particles removed from the item by the rapid decompression is sampled and is tested to determine whether a predetermined contaminant is present in the sample. Depending on the types of contaminants for which the sample is tested, it is possible to detect whether explosives, biological or chemical agents, and/or narcotics residues are present on or in the item being screened.
    Type: Application
    Filed: March 26, 2007
    Publication date: November 1, 2012
    Applicant: L-3 COMMUNICATIONS CYTERRA CORPORATION
    Inventors: David H. Fine, Freeman W. Fraim
  • Energetic material detector
    Patent number: 8292496
    Abstract: In one general aspect, a sample area is energized. A thermal energy status of the sample area is monitored. The thermal energy status including at least one of a radiant energy and a temperature. A thermal signature of a region included in the sample area is determined based on the thermal energy status of the region. The thermal signature is analyzed to determine whether explosive particles are included in the region.
    Type: Grant
    Filed: November 14, 2007
    Date of Patent: October 23, 2012
    Assignee: L-3 Communications CyTerra Corporation
    Inventors: David H. Fine, Edward E. A. Bromberg, Sean C. Christiansen, Steven Bullock, Ravi K. Konduri, Geoffrey Solomon
  • MINE DETECTION
    Publication number: 20120262325
    Abstract: An integrated mine detection system includes a ground penetrating metal detector and a ground penetrating radar detector. The integrated mine detection system includes an integrated search device housing a radio-wave transmitter of the radar detector and a coil of the metal detector. The radio-wave transmitter includes an antenna. The integrated search device includes a radio-wave receiver in the form of a pair of receiving antennas.
    Type: Application
    Filed: April 6, 2012
    Publication date: October 18, 2012
    Applicant: L-3 COMMUNICATIONS CYTERRA CORPORATION
    Inventors: William Steinway, Gregory W. Stilwell, David H. Fine, Paul Crabb, Kevin L. Johnson, Herbert Duvoisin, III, Geoffrey Solomon, Elizabeth Bartosz
  • CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO)
    Publication number: 20120251399
    Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
    Type: Application
    Filed: March 30, 2012
    Publication date: October 4, 2012
    Inventors: David H. Fine, David P. Rounbehler, Gregory Vasquez, Bryan Johnson
  • Conversion of Nitrogen Dioxide (NO2) to Nitric Oxide (NO)
    Publication number: 20120238031
    Abstract: Various systems, devices, NO2 absorbents, NO2 scavengers and NO2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.
    Type: Application
    Filed: May 24, 2012
    Publication date: September 20, 2012
    Inventors: David H. Fine, Gregory Vasquez, David P. Rounbehler
  • Nitrosyl special connector
    Patent number: 8268252
    Abstract: A unique combination of male and female gas connectors for one way transfer of gasses.
    Type: Grant
    Filed: April 26, 2011
    Date of Patent: September 18, 2012
    Assignee: GENO LLC
    Inventors: Jody Fuller, David H. Fine
  • Conversion of nitrogen dioxide (NO) to nitric oxide (NO)
    Patent number: 8246725
    Abstract: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: August 21, 2012
    Assignee: Geno LLC
    Inventors: David R. Rounbehler, David H. Fine