Patents by Inventor David H. Persing

David H. Persing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of a genetic locus encoding resistance to rifampin in mycobacterial cultures and in clinical specimens
    Patent number: 5643723
    Abstract: A method is provided for detecting M. tuberculosis or mutants thereof, particularly rifampin-resistant MTB, in a biological sample comprising: isolating DNA from the biological sample; amplifying the isolated DNA under hybridizing conditions with a primer set that targets portions of the gene encoding rpoB; wherein the pimer set comprises at least one primer that hybridizes under hybridizing conditions to at least one signature nucleotide for M. tuberculosis; and isolating and sequencing the amplified DNA to determine the presence or absence of M. tuberculosis or mutants thereof.
    Type: Grant
    Filed: May 26, 1994
    Date of Patent: July 1, 1997
    Assignees: Roche Molecular Systems, Inc., Mayo Foundation For Medical Education and Research
    Inventors: David H. Persing, John J. Hunt, Karen K. Y. Young, Teresa A. Felmlee, Glenn D. Roberts, A. Christian Whelan