Patents by Inventor David Harper
David Harper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130209408Abstract: The present invention relates in its broadest aspect to combined phage/antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting of P. aeruginosa. Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity against P. aeruginosa and combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates of P. aeruginosa from canine ear infections.Type: ApplicationFiled: February 1, 2013Publication date: August 15, 2013Applicant: Biocontrol LimitedInventors: James Soothill, Catherine Hawkins, David Harper
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Patent number: 8475787Abstract: The invention relates to use of one or more bacteriophages in vivo in a human or animal in order to induce sensitivity to chemical antibiotics in bacterial cells, where such susceptibility is heritable, independent of continuing bacteriophage metabolism within those cells, and does not relate to the destruction of a biofilm to induce such sensitivity.Type: GrantFiled: March 7, 2008Date of Patent: July 2, 2013Assignee: Bio-Control LimitedInventor: David Harper
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Publication number: 20130126723Abstract: The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.Type: ApplicationFiled: December 27, 2012Publication date: May 23, 2013Inventors: Zheng Ouyang, Robert Graham Cooks, Sandilya Venkata Garimella, Jason David Harper, Nicholas Alan Charipar
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Publication number: 20130087850Abstract: Semiconductor devices that include a trench with conductive material for connecting a VDMOS device to a LDMOS device are described. The semiconductor devices include a substrate having a first region and a second region, wherein the second region is disposed on the first region. A trench extends from a top surface of the second region to the first region. The semiconductor substrate includes a VDMOS device formed proximate to the top surface of the second region and a LDMOS device that is also formed proximate to the top surface of the second region. The drain region of the VDMOS device is electrically connected to the source region of the LDMOS device by way of a conductive material disposed in the trench.Type: ApplicationFiled: October 11, 2011Publication date: April 11, 2013Applicant: Maxim Integrated Products, Inc.Inventors: Scott J. Alberhasky, David Harper
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Patent number: 8410431Abstract: The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.Type: GrantFiled: October 5, 2009Date of Patent: April 2, 2013Assignee: Purdue Research FoundationInventors: Zheng Ouyang, Robert Graham Cooks, Sandilya Venkata Garimella, Jason David Harper, Nicholas Alan Charipar
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Patent number: 8412889Abstract: A low-overhead conditional synchronization instruction operates on a synchronization variable which includes a lock bit, a state specification, and bits for user-defined data. The instruction specifies the memory address of the synchronization variable and a condition. During the synchronization instruction the condition is compared to the state specification within an atomic region. The match succeeds if the condition matches the state specification and the lock bit is clear. The synchronization instruction may operate with a cache under a cache coherency protocol, or without a cache, and may include a timeout operand.Type: GrantFiled: October 16, 2008Date of Patent: April 2, 2013Assignee: Microsoft CorporationInventors: David Harper, Burton Smith
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Patent number: 8388946Abstract: The present invention relates in its broadest aspect to combined phage/antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting of P. aeruginosa. Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity against P. aeruginosa and combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates of P. aeruginosa from canine ear infections.Type: GrantFiled: December 21, 2011Date of Patent: March 5, 2013Assignee: BioControl LimitedInventors: James Soothill, Catherine Hawkins, David Harper
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Publication number: 20130016462Abstract: A cordless electrical appliance comprises an appliance part comprising at least two functional components (T1, M1) and a base for supplying electrical power to the appliance part. A cordless electrical connector (6) makes electrical connection between the appliance part and the base part in use. Both of the functional components (T1, M1) are connected between a pair of electrical connections provided by the connector (6) and arranged such that at least one of the functional components (T1, M1) is selectively energised in response to a change in the relative polarities of the two electrical connections. A switch such as a diode (D1) may be provided between the two functional components (T1, M1), so as to switch ON or OFF the current to a functional component (T1, M1) depending on the polarity of the connections.Type: ApplicationFiled: November 4, 2010Publication date: January 17, 2013Applicant: Strix LimitedInventors: James Howitt, David Harper, Colin Cameron
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Publication number: 20120114611Abstract: The present invention relates in its broadest aspect to combined phage/antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting of P. aeruginosa. Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity against P. aeruginosa and combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates of P. aeruginosa from canine ear infections.Type: ApplicationFiled: December 21, 2011Publication date: May 10, 2012Inventors: James Soothill, Catherine Hawkins, David Harper
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Patent number: 8105579Abstract: The present invention relates in its broadest aspect to combined phage/antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting of P. aeruginosa. Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity against P. aeruginosa and combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates of P. aeruginosa from canine ear infections.Type: GrantFiled: October 4, 2010Date of Patent: January 31, 2012Assignee: BioControl LimitedInventors: James Soothill, Catherine Hawkins, David Harper
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Publication number: 20110240844Abstract: The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device.Type: ApplicationFiled: October 5, 2009Publication date: October 6, 2011Applicant: PURDUE RESEARCH FOUNDATIONInventors: Zheng Ouyang, Robert Graham Cooks, Sandilya Venkata Garimella, Jason David Harper, Nicholas Alan Charipar
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Publication number: 20110155199Abstract: A tent having an automatically stored window covering. As a window for the tent is moved from a closed position, where a fabric cover covers the window opening, to an open position, where the fabric cover is partially or fully removed from the opening, the fabric cover automatically stores itself. The only use effort to both open and store the fabric cover is in opening the fabric cover.Type: ApplicationFiled: October 10, 2008Publication date: June 30, 2011Applicant: THE COLEMAN COMPANY, INC.Inventors: David A. Harper, Nicholas W. Vaughn, Chun Ming Feng, Yiyun Culp, Hui Qiang Yu, Trevor J. Hinz, John Trevor Bailey, Michael Wayne Peterson
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Publication number: 20110020290Abstract: The present invention relates in its broadest aspect to combined phage/antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting of P. aeruginosa. Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity against P. aeruginosa and combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates of P. aeruginosa from canine ear infections.Type: ApplicationFiled: October 4, 2010Publication date: January 27, 2011Inventors: James Soothill, Catherine Hawkins, David Harper
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Patent number: 7845067Abstract: A method for assembling an actuator assembly includes providing a first housing portion and a second housing portion; providing a coil, a pole piece, a magnet, and a completed beam; positioning the coil, pole piece, magnet, and completed beam between the housing portions; and coupling the housing portions together.Type: GrantFiled: July 8, 2008Date of Patent: December 7, 2010Assignee: International Business Machines CorporationInventor: David Harper
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Patent number: 7807149Abstract: The present invention relates in its broadest aspect to combined phage/antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting of P. aeruginosa. Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity against P. aeruginosa and combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates of P. aeruginosa from canine ear infections.Type: GrantFiled: July 23, 2004Date of Patent: October 5, 2010Assignee: Biocontrol LimitedInventors: James Soothill, Catherine Hawkins, David Harper
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Publication number: 20100104538Abstract: The invention relates to use of one or more bacteriophages in vivoin a human or animal in order to induce sensitivity to chemical antibiotics in bacterial cells, where such susceptibility is heritable, independent of continuing bacteriophage metabolism within those cells, and does not relate to the destruction of a biofilm to induce such sensitivity.Type: ApplicationFiled: March 7, 2008Publication date: April 29, 2010Applicant: BIOCONTROL LIMITEDInventor: David Harper
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Publication number: 20100100688Abstract: A low-overhead conditional synchronization instruction operates on a synchronization variable which includes a lock bit, a state specification, and bits for user-defined data. The instruction specifies the memory address of the synchronization variable and a condition. During the synchronization instruction the condition is compared to the state specification within an atomic region. The match succeeds if the condition matches the state specification and the lock bit is clear. The synchronization instruction may operate with a cache under a cache coherency protocol, or without a cache, and may include a timeout operand.Type: ApplicationFiled: October 16, 2008Publication date: April 22, 2010Applicant: MICROSOFT CORPORATIONInventors: David Harper, Burton Smith
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Patent number: 7690733Abstract: A hair brush may include a body having a receiving portion at a first end. A cushion pad having an inner surface and an outer surface may be disposed in the receiving portion, and may include a plurality of bristle anchors having an aperture. A plurality of bristles may be tufted into each of the apertures.Type: GrantFiled: August 28, 2008Date of Patent: April 6, 2010Assignee: Goody Products, Inc.Inventors: Paul Spitale, Kim V. Peterson, David Harper, Tianyi Chang
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Patent number: 7660076Abstract: An actuator includes a leadscrew and a helical gear engaging the leadscrew, the helical gear having journals extending from opposite ends thereof. A carriage operatively engages the journals. A relative rotation between the leadscrew and the helical gear creates a relative movement between the carriage and the leadscrew in a direction parallel to an axis of the leadscrew.Type: GrantFiled: September 2, 2005Date of Patent: February 9, 2010Assignee: International Business Machines CorporationInventor: David Harper
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Patent number: 7634502Abstract: A system and method for sharing content among a plurality of users, enables the transfer of electronic content items captured by any of a variety of electronic content devices. The content item can include multiple levels of encoding to facilitate efficient transfer across a communication medium. The content item can be decoded at a recipient device to allow playback, display or other utilization of the content item. Content-specific encoding can be applied to enhance the transportability of the content. A content sharing application can be provided to facilitate content transfer in a computing environment, and can be implemented so as to provide an e-mail like user interface.Type: GrantFiled: January 24, 2005Date of Patent: December 15, 2009Inventors: Paul Colton, Nicolas Nierenberg, David Harper Peckham