Abstract: Methods, systems, and devices for cache block budgeting techniques are described. In some memory systems, a controller may configure a memory device with a cache. The cache may include a first subset of blocks configured to statically operate in a first mode and a second subset of blocks configured to dynamically switch between operating in the first mode and a second mode. A block operating in the second mode may be configured to store relatively more bits per memory cell than a block operating in the first mode. The controller may track and store, for each block of the second subset of blocks, a respective ratio of cycles performed in the first mode to cycles performed in the second mode. The controller may select a block from the second subset of blocks to switch between modes responsive to a trigger and based on the respective ratio for the block.

Abstract: A motion sensory and imaging device capable of acquiring imaging information of the scene and providing at least a near real time pass-through of imaging information to a user. The sensory and imaging device can be used stand-alone or coupled to a wearable or portable device to create a wearable sensory system capable of presenting to the wearer the imaging information augmented with virtualized or created presentations of information.

Abstract: A method and system for dynamically representing the separation for air traffic has been developed. First, air traffic is detected which requires maintenance of a separation distance from an ownship aircraft. The ground speed of the ownship, the ground speed of the air traffic and the current separation distance is determined. A predicted separation distance is calculated following a specific time interval. The predicted separation distance between the air traffic and the ownship is based on a differential in ground speed between the air traffic and the ownship and the specific time interval. The location of the air traffic, the separation distance and the predicted separation distance are all shown on a graphical display onboard the ownship. The separation distance and the predicted separation distance are represented on a non-linear scale on the graphical display.

Abstract: The disclosure relates to nitroimidazoles and related compounds and derivatives, formulations thereof, and their use in the prevention and/or treatment of infectious disease in animals. In particular, the disclosure relates to 5-nitroimidazoles and related compounds and derivatives, formulations thereof, and their use in the prevention and/or treatment of infectious disease in animals including bacterial, viral, parasitic or fungal infections. More particularly, the invention relates to metronidazole and related compounds and derivatives, formulations thereof, and their use in the prevention and/or treatment of infectious disease caused by Clostridium species. Most preferably, the nitroimidazole is metronidazole administered in combination with berberine, or a berberine alkaloid, in a synergistic weight ratio of 1:1 or 1:2.

Abstract: The present invention relates to Bicycle toxin conjugates, methods for preparation, and methods of use for treating cancer.

Abstract: An ASR model includes a first encoder configured to receive a sequence of acoustic frames and generate a first higher order feature representation for a corresponding acoustic frame in the sequence of acoustic frames. The ASR model also includes a second encoder configured to receive the first higher order feature representation generated by the first encoder at each of the plurality of output steps and generate a second higher order feature representation for a corresponding first higher order feature frame. The ASR model also includes a decoder configured to receive the second higher order feature representation generated by the second encoder at each of the plurality of output steps and generate a first probability distribution over possible speech recognition hypothesis. The ASR model also includes a language model configured to receive the first probability distribution over possible speech hypothesis and generate a rescored probability distribution.

Abstract: A magnetic transmission system includes an outer gear ring including an outer plurality of permanent magnets and configured to rotate about a rotational drive axis, an inner gear ring positioned within the outer gear ring and including an inner plurality of permanent magnets magnetically coupled to the outer plurality of permanent magnets, and an eccentric bearing assembly configured to convert orbital motion of the inner gear ring about the rotational drive axis into rotational motion of the eccentric bearing assembly about a bearing rotational axis that is radially offset from the rotational drive axis, and a first drive shaft coupled to the outer gear ring and a second drive shaft coupled to the inner gear ring, wherein the outer gear ring and the inner gear ring are configured to provide a gear ratio between the first drive shaft and the second drive shaft.

Abstract: In one or more embodiments, one or more systems, one or more methods, and/or one or more processes may determine a temperature value within a chassis of an information handling system (IHS); may determine an ambient temperature value outside the chassis based at least on the temperature value within the chassis; may provide the ambient temperature value outside the chassis to a process executing on the IHS; may determine a threshold temperature value associated with at least one processor of the IHS based at least on the ambient temperature value outside the chassis and based at least on a target skin temperature value of the IHS; and may configure the at least one processor based at least on the threshold temperature value associated with the at least one processor.

Abstract: A method includes obtaining a plurality of training samples, determining a minimum integer fixed-bit width representing a maximum quantization of an automatic speech recognition (ASR) model, and training the ASR model on the plurality of training samples using a quantity of random noise. The ASR model includes a plurality of weights that each include a respective float value. The quantity of random noise is based on the minimum integer fixed-bit value. After training the ASR model, the method also includes selecting a target integer fixed-bit width greater than or equal to the minimum integer fixed-bit width, and for each respective weight of the plurality of weights, quantizing the respective weight from the respective float value to a respective integer associated with a value of the selected target integer fixed-bit width. The operations also include providing the quantized trained ASR model to a user device.

Abstract: Glass-based substrates are described herein that may be processed by methods including applying a cover article onto a glass-based substrate, submerging the glass-based substrate in an etchant, and maintaining the submersion of the glass-based substrate in the etchant. The glass-based substrate may include a covered surface portion and an exposed surface portion. At least a portion of the covered surface portion may be in direct contact with the cover article. The covered surface portion may not be in contact with the etchant and the exposed surface portion may be in direct contact with the etchant. The etchant may contact the exposed surface portion and the cover article fora time sufficient to etch the exposed surface portion. The cover article may provide a barrier between the etchant and the covered surface portion for the entirety of the submerging.

Abstract: Methods, systems, and devices for enhanced data reliability in multi-level memory cells are described. For a write operation, a host device may identify a first set of data to be stored by a set of memory cells at a memory device. Based on a quantity of bits within the first set of data being less than a storage capacity of the set of memory cells, the host device may generate a second set of data and transmit a write command including the first and second sets of data to the memory device. For a read operation, the host device may receive a first set of data from the memory device in response to transmitting a read command. The memory device may extract a second set of data from the first set of data and validate a portion of the first set of data using the second set of data.

Abstract: An electronic device with a first off-display input region detects a first portion of an input on the input region. In response to the first portion of the input: when the first portion of the input meets first criteria without a characteristic intensity of the first input increasing above a first intensity threshold, the electronic device provides a first output that indicates a current state of a first attribute of the electronic device without altering the first attribute. The electronic device detects a second portion of the input. In response to the second portion of the input: if the second portion of the first input meets second criteria that require the characteristic intensity of the input increases above the first intensity threshold, the electronic device performs a first operation that alters the first attribute of the electronic device; and otherwise, the electronic device forgoes performing the first operation.

Abstract: This invention relates to berberine alkaloids, formulations thereof and their use for the prevention and/or treatment of infectious disease in animals.

Abstract: Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.

Abstract: A motion sensory and imaging device capable of acquiring imaging information of the scene and providing at least a near real time pass-through of imaging information to a user. The sensory and imaging device can be used stand-alone or coupled to a wearable or portable device to create a wearable sensory system capable of presenting to the wearer the imaging information augmented with virtualized or created presentations of information.

Abstract: The present invention is directed to imidazo[1,2-b][1,2,4]triazines and imidazo[1,2-a]pyrimidines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways.

Abstract: The present invention provides therapeutic, diagnostic, and prognostic methods for cancer. The invention provides methods of treating a cancer, methods of determining whether an individual having a cancer is likely to respond to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of predicting responsiveness of an individual having a cancer to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of selecting a therapy for an individual having a cancer, methods of providing a prognosis for an individual having a cancer, and methods of monitoring a response of an individual having a cancer, based on a blood tumor mutational burden (bTMB) score or a maximum somatic allele frequency (MSAF) from a sample (e.g., a whole blood sample, a plasma sample, a serum sample, or a combination thereof) from the individual.

Abstract: A coated chamber component comprises a chamber component and a coating deposited on a surface of the chamber component, the coating comprising an electrically-dissipative material. The electrically-dissipative material is to provide a dissipative path from the coating to a ground. The coating is uniform, conformal, and has a thickness ranging from about 10 nm to about 900 nm.

Abstract: A method to produce a layered substrate includes depositing a ruthenium layer having a first average grain size on a substrate; annealing the substrate at a temperature and for a period of time sufficient to produce an annealed ruthenium layer having a second average grain size which is greater than the first average grain size; and removing a portion of the ruthenium layer by chemical mechanical planarization to form a planarized ruthenium layer, to produce the layered substrate. A layered substrate is also disclosed.

Abstract: A method includes performing a dry etch process to remove a portion of a first layer disposed on a second layer of a stack of alternating layers. The first layer includes a first material and the second layer includes a second material different from the first material, and the dry etch process forms a passivation layer including a byproduct on surfaces of the second material. A amount of first material of the portion of the first layer remains after performing the dry etch process, The method further includes introducing a halide gas to enhance the passivation layer on the surfaces of the second material.