Abstract: A composition for manufacture of hard hydroxypropyl methyl cellulose capsules comprising a film forming material of hydroxypropyl methyl cellulose having a methoxy content of 27.0-30.0% (w/w), and a hydroxypropoxy content of 4.0-7.5% and as a 2% weight solution, a viscosity of 3.5-6.0 cPs at 20° C., dipping compositions, process for manufacture of hard hydroxypropyl methyl cellulose capsules according to a dip coating process and hard capsule shells.

Abstract: A composition for manufacture of hard hydroxypropyl methyl cellulose capsules comprising a film forming material of hydroxypropyl methyl cellulose having a methoxy content of 27.0-30.0% (w/w), and a hydroxypropoxy content of 4.0-7.5% and as a 2% weight solution, a viscosity of 3.5-6.0 cPs at 20° C., dipping compositions, process for manufacture of hard hydroxypropyl methyl cellulose capsules according to a dip coating process and hard capsule shells.

Abstract: The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer.

Abstract: The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer.

Abstract: A composition for manufacture of hard hydroxypropyl methyl cellulose capsules comprising a film forming material of hydroxypropyl methyl cellulose having a methoxy content of 27.0-30.0% (w/w), and a hydroxypropoxy content of 4.0-7.5% and as a 2% weight solution, a viscosity of 3.5-6.0 cPs at 20° C., dipping compositions, process for manufacture of hard hydroxypropyl methyl cellulose capsules according to a dip coating process and hard capsule shells.

Abstract: The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer.

Abstract: A system and method of medical imaging using a variable speed patient positioning table are provided. The patient positioning table is configured to operate at a plurality of table speeds during acquisition of data from a selected region, such as the thorax region baying predefined cardiac and non-cardiac regions. In a non-cardiac region, the table is controlled to move at one speed and when the cardiac region is detected, the table is controlled to move at another speed, preferably faster than in the cardiac region to speed data acquisition and eliminate motion artifacts.

Abstract: A composition for manufacture of hard hydroxypropyl methyl cellulose capsules comprising a film forming material of hydroxypropyl methyl cellulose having a methoxy content of 27.0-30.0% (w/w), and a hydroxypropoxy content of 4.0-7.5% and as a 2% weight solution, a viscosity of 3.5-6.0 cPs at 20° C., dipping compositions, process for manufacture of hard hydroxypropyl methyl cellulose capsules according to a dip coating process and hard capsule shells.

Abstract: A method of creating 3D models to be used for cardiac interventional procedure planning. Acquisition data is obtained from a medical imaging system and cardiac image data is created in response to the acquisition data. A 3D model is created in response to the cardiac image data and three anatomical landmarks are identified on the 3D model. The 3D model is sent to an interventional system where the 3D model is in a format that can be imported and registered with the interventional system.

Abstract: The present invention, in one form, is a multimode imaging system which, in one embodiment, includes a substantially C-shaped arm movably coupled to a movable base to reduce difficulty of scanning an object. A source assembly having a x-ray source and a detector assembly having a detector are movably coupled to the arm. The source assembly and the detector assembly are independently movable relative to each other and to the arm. In one embodiment, an operator selects one or more modes of operation of the imaging system so that various types of image data are displayed.

Abstract: A volume imaging system which progressively constructs, analyzes, and updates three dimensional models while acquiring cross-sectional data is described. The system constructs and displays three-dimensional renderings, and performs quantitative calculations in real time during the imaging system data collection process, displays interactive three-dimensional renderings in a traditional post-data collection process, as well as prescribes, archives, films, and transmits rendering procedures, parameters, renderings, measurements, and processed data, during data collection and post-acquisition.

Abstract: A method of creating 3D models to be used for cardiac interventional procedure planning. Acquisition data is obtained from a medical imaging system and cardiac image data is created in response to the acquisition data. A 3D model is created in response to the cardiac image data and three anatomical landmarks are identified on the 3D model. The 3D model is sent to an interventional system where the 3D model is in a format that can be imported and registered with the interventional system.

Abstract: A system and method of medical imaging using a variable speed patient positioning table are provided. The patient positioning table is configured to operate at a plurality of table speeds during acquisition of data from a selected region, such as the thorax region baying predefined cardiac and non-cardiac regions. In a non-cardiac region, the table is controlled to move at one speed and when the cardiac region is detected, the table is controlled to move at another speed, preferably faster than in the cardiac region to speed data acquisition and eliminate motion artifacts.

Abstract: The invention includes a technique for efficient multi-slice fast spin echo image acquisition with black blood contrast in cardiac imaging. The technique includes applying a non-selective inversion pulse, followed by a re-inversion pulse that is slice-selective over a region encompassing a plurality of slice selections. Execution of a series of RF excitation pulses with fast spin echo readout is timed such that signal from blood is near a null point before acquiring data for each spatial slice. For greater contrast consistency, the flip angles for the excitation pulses occurring before the null point can be reduced, and those occurring after the null point can be increased.

Abstract: A method for generating an image of an object using a computed tomography (CT) imaging system, which includes at least one x-ray detector array and at least one rotating x-ray source projecting an x-ray beam, includes the steps of identifying a physiological cycle of the object (the cycle comprising a plurality of phases); selecting at least one phase of the object; collecting at least one segment of projection data for each selected phase of the object during each rotation of each x-ray source; generating a projection data set by combining the projection data segments; generating a cross-sectional image of the entire object from the projection data set; and communicating the image or data associated with the image to a remote facility. The remote facility provides remote services over a network.

Abstract: Scalable multislice systems which, in one embodiment, includes a scalable multislice detector, a scalable data acquisition system (SDAS), scalable scan management, control, and image reconstruction processes, and a user interface, are described. More specifically, the user interface is implemented in a host computer for defining the configuration of the imaging system. Particularly, after selection of each scan parameter, the user interface displays the available scan parameter values for the remaining parameters so that the scan objectives are met. More specifically, after selection of each scan parameter, the user interface updates the remaining scan parameters, including prospective and retrospective image thicknesses.

Abstract: The present invention, in one form is an imaging system for generating images of an entire object. In one embodiment, a physiological cycle unit is used to determine the cycle of the moving object. By altering the rotational speed of an x-ray source as a function of the object cycle, segments of projection data are collected for each selected phase of the object during each rotation. After completing a plurality of rotations, the segments of projection data are combined and a cross-sectional image of the selected phase of the object is generated. As a result, minimizing motion artifacts.

Abstract: The present invention, in one form, is an imaging system for generating images of an entire object. In one embodiment, a physiological cycle unit is used to determine the cycle of the moving object. By altering the rotational speed of an x-ray source as a function of the object cycle, segments of projection data are collected for each selected phase of the object during each rotation. After completing a plurality of rotations, the segments of projection data are combined and a cross-sectional image of the selected phase of the object is generated. As a result, minimizing motion artifacts.

Abstract: Methods and apparatus for detecting cell to cell variation to ensure that the maximum allowable channel to channel variation is not exceeded are described. In one embodiment, an algorithm is periodically executed to measure the relative gains in the channels. The gains are measured, for example, by recording the signal from an air scan and normalizing to a common reference. Part of the normalization process includes accounting for the non uniformity of the x-ray beam, for example, the heel effect. It is assumed that the x-ray flux profile in z is slowly changing in the x-direction and is obtained by low pass filtering in x. The normalized values are then compared to a predetermined specification. If any particular cell is not within the specification parameters, then the module in which such cell resides may be replaced. In addition to measuring gain variation and comparing it to a specification, a trending analysis also may be performed.

Abstract: A method is described for optimizing signal-to-noise performance of an imaging system, including the steps of scout-scanning an object to obtain scout scan data; determining a plurality of normalized x-ray input signal factors using the scout scan data; using the normalized x-ray input signal factors to determine at least one system input signal; selecting at least one gain for the object scan using the system input signal; and applying the selected gain corresponding to the system input signal in the object scan.