Abstract: Provided herein are systems, devices, and methods for performing optical multianalyte detection in a sample, such as a human blood sample. The system processes sample in a single-use support pack that holds the blood sample and contains pipette tips, buffers, reagent preparation wells and a monolayer. Sample is transferred from the sample pack to a single-use disc consumable that contains microwells pre-filled with dried chemistries, plasma separation features, and a hematocrit channel. The instrument comprises a cell imager, an absorbance module comprising a spectrophotometer, a fluorescent laser scanning module, and a camera. The system uses only a small amount of blood from a single heparinized sample, to simultaneously provide results for a full panel of routine blood tests spanning electrochemistry, clinical chemistry, hematology, immunoassays and combinations thereof.

Abstract: Provided herein are systems, devices, and methods for performing optical multianalyte detection in a sample, such as a human blood sample. The system processes sample in a single-use support pack that holds the blood sample and contains pipette tips, buffers, reagent preparation wells and a monolayer. Sample is transferred from the sample pack to a single-use disc consumable that contains microwells pre-filled with dried chemistries, plasma separation features, and a hematocrit channel. The instrument comprises a cell imager, an absorbance module comprising a spectrophotometer, a fluorescent laser scanning module, and a camera. The system uses only a small amount of blood from a single heparinized sample, to simultaneously provide results for a full panel of routine blood tests spanning elecochemistry, clinical chemistry, hematology, immunoassays and combinations thereof.

Abstract: Provided herein are systems, devices, and methods for performing optical multianalyte detection in a sample, such as a human blood sample. The system processes sample in a single-use support pack that holds the blood sample and contains pipette tips, buffers, reagent preparation wells and a monolayer. Sample is transferred from the sample pack to a single-use disc consumable that contains microwells pre-filled with dried chemistries, plasma separation features, and a hematocrit channel. The instrument comprises a cell imager, an absorbance module comprising a spectrophotometer, a fluorescent laser scanning module, and a camera. The system uses only a small amount of blood from a single heparinized sample, to simultaneously provide results for a full panel of routine blood tests spanning elecochemistry, clinical chemistry, hematology, immunoassays and combinations thereof.

Abstract: The invention provides a series of conformationally stable kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds.

Abstract: The invention provides a series of conformationally stable kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds.

Abstract: The invention provides a series of conformationally stable kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds.

Abstract: An integrated transparent ultrasonic audio speaker and touchscreen panel, includes a first transparent layer comprising a first base layer and a first conductive layer; and a second transparent layer disposed adjacent the first transparent layer, the second transparent layer comprising a second base layer and a second conductive layer; wherein the second transparent layer is a touchscreen.

Abstract: The invention provides a series of conformationally stable kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds.

Abstract: An integrated transparent ultrasonic audio speaker and touchscreen panel, includes a first transparent layer comprising a first base layer and a first conductive layer; and a second transparent layer disposed adjacent the first transparent layer, the second transparent layer comprising a second base layer and a second conductive layer; wherein the second transparent layer is a touchscreen.

Abstract: Disclosed herein are systems and methods for a water-immune FTIR touchscreen. An optically clear adhesive with an index of refraction between that of water and human skin in the infrared wavelength range is placed below a touchscreen interface substrate. Light beams with a glancing angle greater than a critical glancing angle determined by the index of refraction of the optically clear adhesive do not totally internally reflect at the interface of the touchscreen interface substrate and the optically clear adhesive. Light beams with a glancing angle below the critical glancing angle totally internally reflect. A glancing angle that totally internally reflects at the substrate/optically clear adhesive interface will also totally internally reflect at an interface of the substrate and any water on the surface of the substrate, rendering the touchscreen immune to the effects of water.

Abstract: A coated substrate comprising a nanostructure film formed on a non-planar substrate is described. The coated substrate may further be compliant, optically transparent and/or electrically conductive. Fabrication methods thereof are also described.

Abstract: A nanostructure film, comprising at least one interconnected network of nanostructures, wherein the nanostructure film is optically transparent and electrically conductive. A method for improving the optoelectronic properties of a nanostructure film, comprising: forming a nanostructure film having a thickness that, if uniform, would result in a first optical transparency and a first sheet resistance that are lower than desired; and patterning holes in the nanostructure film, such that a desired higher second optical transparency and a second sheet resistance are achieved. A method for depositing a nanostructure film on a rigid substrate comprises: depositing the nanostructure film on a flexible substrate; and transferring the nanostructure film from the flexible substrate to a rigid substrate, wherein the flexible substrate comprises at least one of a release liner and a heat- or chemical-sensitive adhesive layer.

Abstract: A transparent and conductive film comprising at least one network of graphene flakes is described herein. This film may further comprise an interpenetrating network of other nanostructures, a polymer and/or a functionalization agent(s). A method of fabricating the above device is also described, and may comprise depositing graphene flakes in solution and evaporating solvent therefrom.

Abstract: A solar cell comprising at least one nanostructure-film electrode is discussed. The solar cell may further comprise a different conducting material, such as a conducting polymer, to fill pores in the nanostructure-film. Additionally or alternatively, the solar cell may comprise an electrode grid superimposed on the nanostructure-film. Likewise, the solar cell may have a single or multiple active layer(s), wherein nanostructure-film(s) may form at least semi-transparent anode(s) and/or cathode(s) through use of buffer layer(s).

Abstract: A nanostructure film, comprising at least one interconnected network of nanostructures, wherein the nanostructure film is optically transparent and electrically conductive. A method for improving the optoelectronic properties of a nanostructure film, comprising: forming a nanostructure film having a thickness that, if uniform, would result in a first optical transparency and a first sheet resistance that are lower than desired; and patterning holes in the nanostructure film, such that a desired higher second optical transparency and a second sheet resistance are achieved. A method for depositing a nanostructure film on a rigid substrate comprises: depositing the nanostructure film on a flexible substrate; and transferring the nanostructure film from the flexible substrate to a rigid substrate, wherein the flexible substrate comprises at least one of a release liner and a heat- or chemical-sensitive adhesive layer.

Abstract: A transparent and conductive film comprising at least one network of graphene flakes is described herein. This film may further comprise an interpenetrating network of other nanostructures, a polymer and/or a functionalization agent(s). A method of fabricating the above device is also described, and may comprise depositing graphene flakes in solution and evaporating solvent therefrom.

Abstract: A coated substrate comprising a nanostructure film formed on a non-planar substrate is described. The coated substrate may further be compliant, optically transparent and/or electrically conductive. Fabrication methods thereof are also described.

Abstract: A transparent and conductive film comprising at least one network of graphene flakes is described herein. This film may further comprise an interpenetrating network of other nanostructures, a polymer and/or a functionalization agent(s).

Abstract: An optoelectronic device comprising at least one nanostructure-film electrode is discussed. The optoelectronic device may further comprise a different material, such as a polymer, to fill pores in the nanostructure-film. Additionally or alternatively, the optoelectronic device may comprise an electrode grid superimposed on the nanostructure-film.

Abstract: An optoelectronic device comprising at least one nanostructure-film electrode and fabrication methods thereof are discussed. The optoelectronic device may further comprise a different material to fill in porosity in the nanostructure-film. Additionally, the optoelectronic device may be a solar cell, comprising at least one of a variety of photosensitive active layers.