Abstract: A wearable computing device includes a housing having a wrist-side face configured to sit against a wrist of a user of the wearable computing device when being worn by the user, an electronic display arranged within the housing, a plurality of biometric sensor electrodes positioned on the wrist-side face so as to maintain skin contact with the user when being worn on the wrist by the user, and at least one driver communicatively coupled to the plurality of biometric sensor electrodes. Each of the plurality of biometric sensor electrodes continuously measures, at least, one or more parameters indicative of electrical impedance of the user at a location of the skin contact.

Abstract: A robotic cleaner includes a housing, a suction conduit with an opening, and a leading roller mounted in front of a brush roll. An inter-roller air passageway may be defined between the leading roller and the brush roll wherein the lower portion of the leading roller is exposed to a flow path to the suction conduit and an upper portion of the leading roller is outside of the flow path. Optionally, a combing unit includes a plurality of combing protrusions extending into the leading roller and having leading edges not aligned with a center of the leading roller. Optionally, a sealing strip is located along a rear side of the opening and along a portion of left and right sides of the opening. The underside may define side edge vacuum passageways extending from the sides of the housing partially between the leading roller and the sealing strip towards the opening.

Abstract: A surface cleaning apparatus including a body defining an agitation chamber, an agitator partially disposed within the agitation chamber and configured to rotate about a pivot axis, and a debrider at least partially disposed within the agitation chamber. The agitator includes an elongated body having a first and a second end, a sidewall extending radially outward from the elongated body extending between the first and the second ends, and a plurality of bristles extending radially outward from the elongated body. The plurality of bristles are arranged in at least one row adjacent to the sidewall. The debrider includes a plurality of teeth configured to contact a portion of the sidewall as the agitator rotates about the pivot axis.

Abstract: In various embodiments, the gaming system and method provide The present disclosure relates generally to gaming systems and methods that concurrently display one or more aspects of a primary game and a play of a secondary game within the limited display space available of an electronic gaming machine with a single display device.

Abstract: An example embodiment of an upper room air germicidal light fixture may comprise a light source configured to emit germicidal light and may further comprise one or more lower and upper baffle assemblies disposed adjacent to the light source. Said upper and lower baffle assemblies may be configured to enable air to flow through them and to block or substantially dissipate incident light rays from the light source. One or more apertures may be defined by the openings between a corresponding set of upper and lower baffle assemblies, wherein said light can exit the fixture through said apertures. When the germicidal light fixture is disposed in a room, surrounding room air may contact light exiting the apertures of said fixture, and room air traveling through said fixture may contact light inside and between the one or more upper and lower baffle assemblies.

Abstract: A bead delivery disk, system and method of delivering flavor beads to a tobacco rod or tow including a bead source, a bead delivery disk in communication with the bead source, including a central disk portion having front and back sides and a first central thickness, an inner annular rim around the central disk portion, the inner annular rim having a second thickness less than said first thickness, a series of pockets spaced around the inner annular rim and multiple vacuum transmission apertures located on one side of the disk, each aperture communicating with at least one of the pockets.

Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a TNF-alpha inhibitor.

Abstract: A bead delivery disk, system and method of delivering flavor beads to a tobacco rod or tow including a bead source, a bead delivery disk in communication with the bead source, including a central disk portion having front and back sides and a first central thickness, an inner annular rim around the central disk portion, the inner annular rim having a second thickness less than said first thickness, a series of pockets spaced around the inner annular rim and multiple vacuum transmission apertures located on one side of the disk, each aperture communicating with at least one of the pockets.

Abstract: In an example embodiment of the disclosed technology, a plant disinfection apparatus is provided that may comprise a support device configured to directly or indirectly support one or more UVC probes beneath the support device. The one or more UVC probes may each comprise a relatively elongated shape comprising a major axis Y, a light source that emits UVC light in a predominantly perpendicular distribution pattern relative to axis Y, and a suspension device configured to directly or indirectly attach to the support device. The UVC probe may be configured to be raised and lowered in a relatively vertical orientation and may further comprise a means of conveying power to the UVC light source. The one or more UVC probes may be configured to be lowered into the foliage of one or more plants disposed beneath the plant disinfection apparatus.

Abstract: In various embodiments, the present disclosure relates generally to gaming systems and methods that concurrently display one or more aspects of a primary game and a play of a secondary game within the limited display space available of an electronic gaming machine with a single display device.

Abstract: Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.

Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an immunomodulator.

Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an integrin inhibitor. In particular, the disclosure features the topical treatment of sections and subsections of the gastrointestinal tract by integrin inhibitors (like vedolizumab) using an ingestible device that can detect its whereabouts in the Gl tract by using reflectance and which is programmed to release the drugs at a given site or proximal thereto, to treat gastrointestinal inflammatory diseases. The device has hardware storage devices with instructions on board to determine the location and release the formulations. Combination therapies are claimed as well in which the integrin inhibitor is added systemically and another agent (e.g. JAK inhibitor, TNF-alpha inhibitor or IL-12/IL-23 inhibitor) is added topically by means of the ingestible device. The topical administration is said to reduce the side effects associated with systemic treatment.

Abstract: This disclosure features methods and compositions for treating inflammatory disorders or conditions that arise in a tissue originating from the endoderm using an immune modulator.

Abstract: An example embodiment of an upper room air germicidal light fixture may comprise a light source configured to emit germicidal light and may further comprise one or more lower and upper baffle assemblies disposed adjacent to the light source. Said upper and lower baffle assemblies may be configured to enable air to flow through them and to block or substantially dissipate incident light rays from the light source. One or more apertures may be defined by the openings between a corresponding set of upper and lower baffle assemblies, wherein said light can exit the fixture through said apertures. When the germicidal light fixture is disposed in a room, surrounding room air may contact light exiting the apertures of said fixture, and room air traveling through said fixture may contact light inside and between the one or more upper and lower baffle assemblies.

Abstract: An apparatus for the formation of machine-made tobacco rods for use in the production of smoking articles, such as cigars, from tobacco comprising a tacky material. The apparatus includes a pair of transfer and compression belts for receiving and compressing the stream of tobacco, the transfer and compression; a pair of squeeze bars for compressing the tobacco in a direction perpendicular to the pair of transfer and compression belts, the pair of squeeze bars produced from a material comprising a poly(aryl ether ketone); a tongue for receiving the compressed tobacco, the tongue produced from a material comprising a poly(aryl ether ketone); and a folder for folding a wrapper material around the compressed tobacco so as to form a continuous rod of tobacco, the wrapper material provided from a source of wrapper material, the folder produced from a material comprising a poly(aryl ether ketone).

Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a JAK or other kinase inhibitor.

Abstract: An apparatus for the formation of machine-made tobacco rods for use in the production of smoking articles, such as cigars, from tobacco comprising a tacky material. The apparatus includes a pair of transfer and compression belts for receiving and compressing the stream of tobacco, the transfer and compression; a pair of squeeze bars for compressing the tobacco in a direction perpendicular to the pair of transfer and compression belts, the pair of squeeze bars produced from a material comprising a poly(aryl ether ketone); a tongue for receiving the compressed tobacco, the tongue produced from a material comprising a poly(aryl ether ketone); and a folder for folding a wrapper material around the compressed tobacco so as to form a continuous rod of tobacco, the wrapper material provided from a source of wrapper material, the folder produced from a material comprising a poly(aryl ether ketone).

Abstract: A light modifying apparatus is provided, which may comprise a curved outer layer comprising a substrate configured to modify light, wherein the curved outer layer may have an arc of length X. A second curved me be disposed on, or in close proximity to the back surface of the outer layer, and wherein the second curved layer may have an arc of length Y wherein length Y is less than length X, and wherein the second curved layer may comprise a substrate comprising one or more surfaces comprising a lenticular lens configuration. An optional third layer may be provided which may comprise a substrate comprising one or more surfaces comprising a lenticular lens configuration.