Abstract: Methods of preparing papillomavirus nucleic acid transfer vectors, in-disassembled cluding by disassembly/reassembly of papillomavirus L1 and L2 virus-like particles, in a defined, cell-free high-efficiency production protocol. These methods may be used to efficiently encapsidate desired moieties, e.g., toxic or therapeutic nucleic acids such as DNA and RNA, and the resultant pseudovirus particles may be used as in vivo delivery vehicles.

Abstract: Many users of information handling systems use applications to create, manage, and/or save files containing information. Encryption of the files secures the data against access by unintended recipients. Information handling systems may be designed to perform encryption in the background with minimal user input. For example, applications, application plug-ins, or operating system (OS) level system services may facilitate encryption and decryption of application files with minimal user input. Such applications, plugins, and services may allow applications to interact with encryption systems, such as virtual file systems, and may direct file save and access operations through the encryption systems, automatically encrypting and decrypting files selected by the user without exposing the user to cumbersome or confusing encryption options.

Abstract: Many users of information handling systems use applications to create, manage, and/or save files containing information. Encryption of the files secures the data against access by unintended recipients. Information handling systems may be designed to perform encryption in the background with minimal user input. For example, applications, application plug-ins, or operating system (OS) level system services may facilitate encryption and decryption of application files with minimal user input. Such applications, plugins, and services may allow applications to interact with encryption systems, such as virtual file systems, and may direct file save and access operations through the encryption systems, automatically encrypting and decrypting files selected by the user without exposing the user to cumbersome or confusing encryption options.

Abstract: Methods and compositions relating to anti-CD22 antibodies with high binding affinity, and immunoconjugates comprising the anti-CD22 antibody linked to a therapeutic agent such as a Pseudomonas exotoxin or a detectable label. The invention provides diagnostic methods, and means to inhibit the growth of malignant B cells.

Abstract: A mounting assembly for mounting a toy to a rail and for supporting said toy on said rail, includes an upper bracket and a lower bracket, the upper bracket permitting the mobile to move vertically up and down, and the lower bracket permitting the mobile to move horizontally from side to side parallel to the rail, the lower bracket also attaching to the rail and supporting the upper bracket. The brackets are constructed to be loosened to permit disinfecting, but do not completely detach.

Abstract: An embodiment of the present invention may provide a method and system for event notification, performance and/or risk assessment based on mission impact that may be due to actual and/or potential info-structure disruptions. In one embodiment of the present invention, one or more network event messages may be received from a source or multiple sources. An operational mission impacted by a network event may be identified based on a received network event message and mapping with an operational architecture task identifier associated with the impacted operational mission and an element identifier associated with a source element.

Abstract: The present invention provides compositions comprising a chimeric molecule comprising a cytotoxin that inhibits protein synthesis and an agent that inactivates an anti-apoptotic BCL-2 family member protein and methods of inhibiting the growth of or promoting the apoptosis of an aberrantly proliferating cell population by co-administering the chimeric molecule and the agent that inactivates an anti-apoptotic BCL-2 family member protein.

Abstract: The invention provides novel recombinant immunotoxins comprising domain III of cholix toxin and exotoxin from Vibrio cholerae. The present invention further provides methods for using the compositions of the present invention to (i) induce apoptosis in a cell bearing one or more surface markers (ii) inhibit unwanted growth, hyperproliferation or survival of a cell bearing one or more cell surface markers, (iii) treat a condition, such as a cancer, (iv) provide therapy for a mammal having developed antibodies to Pseudomonas exotoxin A, and (v) provide therapy for a mammal having developed a disease caused by the presence of cells bearing one or more cell surface marker.

Abstract: This invention provides bioactive conjugates. The bioactive conjugates include: (1) a cell recognition moiety that binds to ?2 macroglobulin receptor ?2-MR and (2) a bioactive moiety which: (a) has a biological activity, (b) does not function solely as an immunogen to invoke an immune response and (c) does not have ADP ribosylating activity. The bioactive conjugates of this invention are useful in methods of transporting the bioactive moiety across a polar epithelial membrane. Thus, this invention provides methods for parenteral administration of proteins without injection.

Abstract: A recording system employing a magneto-resistive (MR) element senses a resistance value of the MR element and generates one or more MR resistance (MRR) signal values based on the sensed MR element resistance value. The MRR signal values might be, for example, current or voltage values proportional or inversely proportional to the MR element resistance value. The MRR signal values might be employed to control one or more of: i) a unity gain bandwidth of a bias loop for the MR element, ii) an MR read head preamplifier low corner frequency, and iii) a slew rate across the MR element.

Abstract: Methods and compositions relating to anti-CD22 antibodies with high binding affinity, and immunoconjugates comprising the anti-CD22 antibody linked to a therapeutic agent such as a Pseudomonas exotoxin or a detectable label. The invention provides diagnostic methods, and means to inhibit the growth of malignant B cells.

Abstract: This invention provides Pseudomonas exotoxin A-like chimeric immunogens that include a non-native epitope in the Ib domain of Pseudomonas exotoxin. Methods of eliciting an immune response using these immunogens also are provided.

Abstract: A snow sled for use by a seated rider includes a body section, a seat section having an underside for engaging the snow and a top side for receiving the seated rider, the seat section attached to the body section, a foot section having an underside for engaging the snow and positioned forward of the seat section when the snow sled is deployed in the riding configuration and positioned adjacent the seat section when the snow sled is retracted into the stowable configuration, and a handlebar arrangement connecting the body section to the foot section.

Abstract: A snow sled for use by a seated rider includes a body section, a seat section having an underside for engaging the snow and a top side for receiving the seated rider, the seat section attached to the body section, a foot section having an underside for engaging the snow and positioned forward of the seat section when the snow sled is deployed in the riding configuration and positioned adjacent the seat section when the snow sled is retracted into the stowable configuration, and a handlebar arrangement connecting the body section to the foot section.

Abstract: Methods and compositions relating to recombinant anti-CD22 antibodies with high binding affinity, and immunoconjugates comprising the anti-CD22 antibody linked to a therapeutic agent such as a Pseudomonas exotoxin or a detectable label. The invention provides diagnostic methods, and means to inhibit the growth of malignant B cells.

Abstract: This invention provides methods of eliciting a secretory IgA-mediated immune response in a subject by administering a Pseudomonas exotoxin A-like chimeric immunogens that include a non-native epitope in the Ib domain of Pseudomonas exotoxin. Compositions comprising secretory IgA antibodies that specifically recognize an epitope of HIV-1 also are provided.

Abstract: An embodiment of the present invention provides an apparatus for propelling a fluid in a spiral stream. The apparatus includes a housing, and a cap member connected to the housing and discharges a stream of fluid in a spiral stream. A large gear member is coupled to the cap member for causing the cap member to rotate when the large gear member rotates. A gear assembly transfers rotation of an impeller to the large gear member when the impeller is contacted by fluid passing through an impeller opening in am impeller support. An embodiment of the present invention also provides a method for propelling a fluid in a spiral stream.

Abstract: A method for discharging a fluid in an inflated assembly. The method includes inflating a roller assembly having a roller, rotatably coupling the inflated roller assembly to an inflated structure, and discharging a fluid against the inflated roller assembly to cause the inflated roller to rotate. An inflated water toy comprising an inflated structure, and an inflated roller assembly rotatably supported by the inflated structure, and a conduit assembly for discharging a fluid against an inflated roller of the inflated roller assembly and for conducting fluid to other locations on the inflated structure for dispersing the liquid from the other locations.

Abstract: The invention provides chimeric proteins comprising a non-toxic Pseudomonas exotoxin A sequence and a Type IV pilin loop sequence, wherein the Type IV loop sequence is inserted within the non-toxic Pseudomonas exotoxin A. The invention also provides polynucleotides encoding the chimeric proteins, and compositions comprising the polynucleotides or the chimeric proteins. The invention also provides methods for using the chimeric proteins, polynucleotides and compositions of the invention.