Patents by Inventor David J. Fitzgerald

David J. Fitzgerald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200010850
    Abstract: Methods of preparing papillomavirus nucleic acid transfer vectors, in-disassembled cluding by disassembly/reassembly of papillomavirus L1 and L2 virus-like particles, in a defined, cell-free high-efficiency production protocol. These methods may be used to efficiently encapsidate desired moieties, e.g., toxic or therapeutic nucleic acids such as DNA and RNA, and the resultant pseudovirus particles may be used as in vivo delivery vehicles.
    Type: Application
    Filed: February 20, 2018
    Publication date: January 9, 2020
    Inventors: John T. SCHILLER, Carla V. CORREIA CERQUEIRA,, Patricia M. DAY, Douglas R. LOWY, David J. FITZGERALD
  • Patent number: 10489600
    Abstract: Many users of information handling systems use applications to create, manage, and/or save files containing information. Encryption of the files secures the data against access by unintended recipients. Information handling systems may be designed to perform encryption in the background with minimal user input. For example, applications, application plug-ins, or operating system (OS) level system services may facilitate encryption and decryption of application files with minimal user input. Such applications, plugins, and services may allow applications to interact with encryption systems, such as virtual file systems, and may direct file save and access operations through the encryption systems, automatically encrypting and decrypting files selected by the user without exposing the user to cumbersome or confusing encryption options.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: November 26, 2019
    Assignee: Dell Products L.P.
    Inventors: James D. Testerman, David J. Fitzgerald, Oliver C. Ryan, Vadamalar Varadarajan, Adam W. Meek, Venkata S N M Prayaga, Nitin D. Dixit
  • Publication number: 20190147430
    Abstract: Systems, methods, and computer-readable media are provided for customizing payment sessions.
    Type: Application
    Filed: November 13, 2018
    Publication date: May 16, 2019
    Inventors: Shuohui Chen, David L. Neumann, Eric J. Gray, Fei Gao, Lincoln L. Barker, Michael K. Chu, Payam Mirrashidi, Timothy Russo, Todd J. Fitzgerald, Wayne A. Yap, Yichen Liu, Yu Liu, Bilung Lee, Mingzhu Zhu
  • Publication number: 20180314838
    Abstract: Many users of information handling systems use applications to create, manage, and/or save files containing information. Encryption of the files secures the data against access by unintended recipients. Information handling systems may be designed to perform encryption in the background with minimal user input. For example, applications, application plug-ins, or operating system (OS) level system services may facilitate encryption and decryption of application files with minimal user input. Such applications, plugins, and services may allow applications to interact with encryption systems, such as virtual file systems, and may direct file save and access operations through the encryption systems, automatically encrypting and decrypting files selected by the user without exposing the user to cumbersome or confusing encryption options.
    Type: Application
    Filed: April 28, 2017
    Publication date: November 1, 2018
    Applicant: Dell Products L.P.
    Inventors: James D. Testerman, David J. Fitzgerald, Oliver C. Ryan, Vadamalar Varadarajan, Adam W. Meek, Venkata SNM Prayaga, Nitin D. Dixit
  • Patent number: 9592304
    Abstract: Methods and compositions relating to anti-CD22 antibodies with high binding affinity, and immunoconjugates comprising the anti-CD22 antibody linked to a therapeutic agent such as a Pseudomonas exotoxin or a detectable label. The invention provides diagnostic methods, and means to inhibit the growth of malignant B cells.
    Type: Grant
    Filed: April 30, 2009
    Date of Patent: March 14, 2017
    Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: David J. FitzGerald, Ira Pastan, Elizabeth Mansfield, Robert Kreitman
  • Patent number: 9527000
    Abstract: A mounting assembly for mounting a toy to a rail and for supporting said toy on said rail, includes an upper bracket and a lower bracket, the upper bracket permitting the mobile to move vertically up and down, and the lower bracket permitting the mobile to move horizontally from side to side parallel to the rail, the lower bracket also attaching to the rail and supporting the upper bracket. The brackets are constructed to be loosened to permit disinfecting, but do not completely detach.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: December 27, 2016
    Assignee: PLAYABILITY TOYS, LLC
    Inventors: Martin P. Fox, David J. FitzGerald
  • Patent number: 8347145
    Abstract: An embodiment of the present invention may provide a method and system for event notification, performance and/or risk assessment based on mission impact that may be due to actual and/or potential info-structure disruptions. In one embodiment of the present invention, one or more network event messages may be received from a source or multiple sources. An operational mission impacted by a network event may be identified based on a received network event message and mapping with an operational architecture task identifier associated with the impacted operational mission and an element identifier associated with a source element.
    Type: Grant
    Filed: January 13, 2005
    Date of Patent: January 1, 2013
    Assignee: Northrop Grumman Systems Corporation
    Inventors: David J. Fitzgerald, Eric S. Jensen, Daniel P. Lindorf, Scott E. Sage
  • Publication number: 20120276190
    Abstract: The present invention provides compositions comprising a chimeric molecule comprising a cytotoxin that inhibits protein synthesis and an agent that inactivates an anti-apoptotic BCL-2 family member protein and methods of inhibiting the growth of or promoting the apoptosis of an aberrantly proliferating cell population by co-administering the chimeric molecule and the agent that inactivates an anti-apoptotic BCL-2 family member protein.
    Type: Application
    Filed: February 27, 2012
    Publication date: November 1, 2012
    Applicant: The Government of the U.S.A. as Represented By the Secretary of the Dept. of Health & Human Services
    Inventor: David J. Fitzgerald
  • Publication number: 20110250199
    Abstract: The invention provides novel recombinant immunotoxins comprising domain III of cholix toxin and exotoxin from Vibrio cholerae. The present invention further provides methods for using the compositions of the present invention to (i) induce apoptosis in a cell bearing one or more surface markers (ii) inhibit unwanted growth, hyperproliferation or survival of a cell bearing one or more cell surface markers, (iii) treat a condition, such as a cancer, (iv) provide therapy for a mammal having developed antibodies to Pseudomonas exotoxin A, and (v) provide therapy for a mammal having developed a disease caused by the presence of cells bearing one or more cell surface marker.
    Type: Application
    Filed: June 4, 2009
    Publication date: October 13, 2011
    Applicant: The Government of the United States of America as represented by the Secretary of the Department....
    Inventors: David J. Fitzgerald, Robert Sarnovsky
  • Patent number: 7824695
    Abstract: This invention provides bioactive conjugates. The bioactive conjugates include: (1) a cell recognition moiety that binds to ?2 macroglobulin receptor ?2-MR and (2) a bioactive moiety which: (a) has a biological activity, (b) does not function solely as an immunogen to invoke an immune response and (c) does not have ADP ribosylating activity. The bioactive conjugates of this invention are useful in methods of transporting the bioactive moiety across a polar epithelial membrane. Thus, this invention provides methods for parenteral administration of proteins without injection.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: November 2, 2010
    Assignees: The United States of America as represented by the Department of Health and Human Services, Genentech, Inc.
    Inventors: David J. FitzGerald, Randall J. Mrsny, Marian McKee, Ann Daugherty
  • Patent number: 7724460
    Abstract: A recording system employing a magneto-resistive (MR) element senses a resistance value of the MR element and generates one or more MR resistance (MRR) signal values based on the sensed MR element resistance value. The MRR signal values might be, for example, current or voltage values proportional or inversely proportional to the MR element resistance value. The MRR signal values might be employed to control one or more of: i) a unity gain bandwidth of a bias loop for the MR element, ii) an MR read head preamplifier low corner frequency, and iii) a slew rate across the MR element.
    Type: Grant
    Filed: January 13, 2005
    Date of Patent: May 25, 2010
    Assignee: Agere Systems Inc.
    Inventors: David J. Fitzgerald, Jeffrey A. Gleason, James P. Howley, Scott M. O'Brien, Michael P. Straub
  • Publication number: 20090305411
    Abstract: Methods and compositions relating to anti-CD22 antibodies with high binding affinity, and immunoconjugates comprising the anti-CD22 antibody linked to a therapeutic agent such as a Pseudomonas exotoxin or a detectable label. The invention provides diagnostic methods, and means to inhibit the growth of malignant B cells.
    Type: Application
    Filed: April 30, 2009
    Publication date: December 10, 2009
    Applicants: SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, National Institute of Health, Office of Technology Transfer
    Inventors: David J. FitzGerald, Ira Pastan, Elizabeth Mansfield, Robert Kreitman
  • Publication number: 20090269368
    Abstract: This invention provides Pseudomonas exotoxin A-like chimeric immunogens that include a non-native epitope in the Ib domain of Pseudomonas exotoxin. Methods of eliciting an immune response using these immunogens also are provided.
    Type: Application
    Filed: December 20, 2007
    Publication date: October 29, 2009
    Applicant: The Gov. of the USA as Represented by the Secretary of the Dept.of Health and Human Services
    Inventor: David J. FitzGerald
  • Publication number: 20090243239
    Abstract: A snow sled for use by a seated rider includes a body section, a seat section having an underside for engaging the snow and a top side for receiving the seated rider, the seat section attached to the body section, a foot section having an underside for engaging the snow and positioned forward of the seat section when the snow sled is deployed in the riding configuration and positioned adjacent the seat section when the snow sled is retracted into the stowable configuration, and a handlebar arrangement connecting the body section to the foot section.
    Type: Application
    Filed: June 8, 2009
    Publication date: October 1, 2009
    Inventor: David J. Fitzgerald
  • Patent number: 7552930
    Abstract: A snow sled for use by a seated rider includes a body section, a seat section having an underside for engaging the snow and a top side for receiving the seated rider, the seat section attached to the body section, a foot section having an underside for engaging the snow and positioned forward of the seat section when the snow sled is deployed in the riding configuration and positioned adjacent the seat section when the snow sled is retracted into the stowable configuration, and a handlebar arrangement connecting the body section to the foot section.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: June 30, 2009
    Assignee: Wham-O, Inc.
    Inventor: David J. Fitzgerald
  • Patent number: 7541034
    Abstract: Methods and compositions relating to recombinant anti-CD22 antibodies with high binding affinity, and immunoconjugates comprising the anti-CD22 antibody linked to a therapeutic agent such as a Pseudomonas exotoxin or a detectable label. The invention provides diagnostic methods, and means to inhibit the growth of malignant B cells.
    Type: Grant
    Filed: March 19, 1998
    Date of Patent: June 2, 2009
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: David J. Fitzgerald, Ira Pastan, Elizabeth Mansfield, Robert Kreitman
  • Publication number: 20090081235
    Abstract: This invention provides methods of eliciting a secretory IgA-mediated immune response in a subject by administering a Pseudomonas exotoxin A-like chimeric immunogens that include a non-native epitope in the Ib domain of Pseudomonas exotoxin. Compositions comprising secretory IgA antibodies that specifically recognize an epitope of HIV-1 also are provided.
    Type: Application
    Filed: July 8, 2008
    Publication date: March 26, 2009
    Applicants: OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, GENENTECH, INC.
    Inventors: DAVID J. FITZGERALD, RANDALL J. MRSNY
  • Publication number: 20080302432
    Abstract: An embodiment of the present invention provides an apparatus for propelling a fluid in a spiral stream. The apparatus includes a housing, and a cap member connected to the housing and discharges a stream of fluid in a spiral stream. A large gear member is coupled to the cap member for causing the cap member to rotate when the large gear member rotates. A gear assembly transfers rotation of an impeller to the large gear member when the impeller is contacted by fluid passing through an impeller opening in am impeller support. An embodiment of the present invention also provides a method for propelling a fluid in a spiral stream.
    Type: Application
    Filed: June 6, 2007
    Publication date: December 11, 2008
    Applicant: WHAM-O, Inc.
    Inventor: David J. Fitzgerald
  • Publication number: 20080245396
    Abstract: A method for discharging a fluid in an inflated assembly. The method includes inflating a roller assembly having a roller, rotatably coupling the inflated roller assembly to an inflated structure, and discharging a fluid against the inflated roller assembly to cause the inflated roller to rotate. An inflated water toy comprising an inflated structure, and an inflated roller assembly rotatably supported by the inflated structure, and a conduit assembly for discharging a fluid against an inflated roller of the inflated roller assembly and for conducting fluid to other locations on the inflated structure for dispersing the liquid from the other locations.
    Type: Application
    Filed: April 9, 2007
    Publication date: October 9, 2008
    Applicant: WHAM-O Corporation
    Inventor: David J. Fitzgerald
  • Patent number: D562929
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: February 26, 2008
    Assignee: Wham-O Corporation
    Inventor: David J. Fitzgerald