Abstract: In one example, a system includes an elongated body defining a lumen where the elongated body includes a proximal portion and a distal portion. An anchoring member may be positioned on the proximal portion of the elongated body. The system further includes a sensor located on the elongated body where the sensor may be configured to sense at least one flow parameter of a fluid within the lumen. In some examples, the system includes processing circuitry configured to determine at least one of a density parameter or a temperature parameter of the fluid in the lumen based on the sensed at least one flow parameter of the fluid.

Abstract: In some examples, a device includes a catheter insert elongated body defining a body lumen, the catheter insert elongated body being configured to be at least partially inserted to a catheter lumen defined by a catheter without covering a first fluid opening of the catheter and to form a fluidically tight coupling with the catheter, and one or more sensors positioned on the elongated body. At least one of the one or more sensors are configured to sense a substance of interest. The catheter insert elongated body includes a material that is a substantially non-permeable to the substance of interest.

Abstract: An RF amplifier utilizes first and second main amplifiers in a balanced amplifier configuration with first and second auxiliary amplifiers connected in parallel across the first and second main amplifiers, respectively. The main and the auxiliary amplifiers are biased such that the third-order nonlinearity components in the combined output current are reduced. A common or independent bias control circuit(s) control(s) the DC operating bias of the auxiliary amplifiers and establishes DC operating points on curves representing third-order nonlinear components within the drain current having a positive slope (opposite to the corresponding slope of the main amplifiers). This results in reduction of overall third-order nonlinear components in combined currents at the output. In another embodiment, a phase shift of an input to one auxiliary amplifier is used to provide a peak in minimization at a frequency associated with the phase shift.

Abstract: In some examples, a medical device includes an elongated body defining an inner lumen. The medical device further includes an anchoring member and a first sensor at a proximal portion of the elongated body, and a second sensor at a distal portion of the elongated body or distal to a distal end of the elongated body. The second sensor is configured to sense a substance of interest and the elongated body comprises a material that is a substantially non-permeable to the substance of interest.

Abstract: Example devices and techniques are disclosed for delivering neurostimulation therapy transesophageally. An example device includes stimulation circuitry configured to generate a transesophageal stimulation signal. The example device includes memory configured to store stimulation parameters that at least partially define the transesophageal stimulation signal and processing circuitry communicatively coupled to the memory, and the stimulation circuitry. The processing circuitry is configured to determine a maximum transesophageal stimulation amplitude value. The processing circuitry is configured to control the stimulation circuitry to generate the transesophageal stimulation signal based at least in part on at least one of the stimulation parameters or the maximum transesophageal stimulation amplitude such that an amplitude of the transesophageal stimulation signal does not exceed the maximum transesophageal stimulation amplitude.

Abstract: In some examples, a device includes a catheter insert elongated body defining a body lumen, the catheter insert elongated body being configured to be at least partially inserted to a catheter lumen defined by a catheter without covering a first fluid opening of the catheter and to form a fluidically tight coupling with the catheter, and one or more sensors positioned on the elongated body. At least one of the one or more sensors are configured to sense a substance of interest. The catheter insert elongated body includes a material that is a substantially non-permeable to the substance of interest.

Abstract: A method of timing a resonant frequency of a nanoelectromechanical systems (NEMS) drum device is performed by applying a gate voltage between the drum membrane [100] and a back gate [104] to alter the resonant frequency of the membrane to a desired frequency; photoionizing the drum membrane with a laser to detune the membrane resonant frequency to a ground state frequency; and releasing the gate voltage to set the membrane to the desired resonant frequency. The method provides the basis for various applications including NEMS memory and photodetection techniques. The NEMS device may be implemented as a graphene/hBN membrane [100] suspended on a Si02 layer [102] deposited on a Si substrate [104].

Abstract: A novel alfalfa variety designated 14XXP21R and seed, plants and plant parts thereof are provided. Methods for producing an alfalfa plant comprise crossing alfalfa variety 14XXP21R with another alfalfa plant. Methods for producing an alfalfa plant containing in its genetic material one or more traits transgenes or locus conversions introgressed into 14XXP21R through backcross conversion and/or transformation are provided and the alfalfa seed, plant and plant part produced thereby. Alfalfa seed, plants or plant parts produced by crossing alfalfa variety 14XXP21R or a locus or trait conversion of 14XXP21R with another alfalfa plant or population are disclosed. Alfalfa populations derived from alfalfa variety 14XXP21R, methods for producing other alfalfa populations derived from alfalfa variety 14XXP21R and the alfalfa populations and their parts derived by the use of those methods.

Abstract: Fluid management in surgical procedures. At least some of the example embodiments are methods including: pumping surgical fluid through a tube to a surgical site by a fluid controller operating in a first mode, the first mode comprising a first relationship of fluid flow and pressure drop across the tube and cannula, and the first mode comprising a first set of proportional, integral, and differential (PID) parameters; and then pumping surgical fluid through the tube to the surgical site with the fluid controller operating in a second mode, the second mode comprising a second relationship of fluid flow and pressure drop across the tube and cannula, the second relationship different than the first relationship, and the second mode comprising a second set of PID parameters used, the second set of PID parameters different than the first set of PID parameters.

Abstract: A novel alfalfa variety designated 14XXP23R and seed, plants and plant parts thereof are provided. Methods for producing an alfalfa plant comprise crossing alfalfa variety 14XXP23R with another alfalfa plant. Methods for producing an alfalfa plant containing in its genetic material one or more traits transgenes or locus conversions introgressed into 14XXP23R through backcross conversion and/or transformation are provided and the alfalfa seed, plant and plant part produced thereby. Alfalfa seed, plants or plant parts produced by crossing alfalfa variety 14XXP23R or a locus or trait conversion of 14XXP23R with another alfalfa plant or population are disclosed. Alfalfa populations derived from alfalfa variety 14XXP23R, methods for producing other alfalfa populations derived from alfalfa variety 14XXP23R and the alfalfa populations and their parts derived by the use of those methods.

Abstract: This current invention is a system and app that is an Active Shooter Shield application. It is a technological process that, when put in motion, create a real-time active shoot or incident “shield.” This invention essentially provides a way for parties to obtain location specific real-time information at the place of such “incident” and to communicate this information in a very structured manner for those tasked with ending the active incident, preparing for and addressing the injuries and saving lives.

Abstract: An example device includes memory configured to store an observer and processing circuitry communicatively coupled to the memory. The processing circuitry is configured to receive, from an oxygen sensor, an oxygen sensor signal indicative of an amount of dissolved oxygen in a fluid, wherein the oxygen sensor is located in a distal portion of a catheter or distal to a distal end of the catheter, and wherein the fluid flows to the oxygen sensor from a location within a patient. The processing circuitry is configured to determine, based on the oxygen sensor signal, a measurement of the amount of dissolved oxygen in the fluid. The processing circuitry is configured to apply the observer to the measurement of the amount of dissolved oxygen in the fluid. The processing circuitry is configured to determine, based on the observer, an estimate of an amount of dissolved oxygen in the fluid at the location.

Abstract: Example devices and techniques for sensing a parameter of a substance of interest are disclosed. An example catheter includes an elongated body defining a lumen. The lumen is configured to receive or house an oxygen sensing element. When the oxygen sensing element is located in a proximal portion of the lumen, the oxygen sensing element is configured to sense an amount of dissolved oxygen in a fluid external to the lumen. The catheter is configured to block ingress of the fluid into the lumen while the oxygen sensing element senses the amount of dissolved oxygen.

Abstract: An example device includes memory and processing circuitry communicatively coupled to the memory. The processing circuitry is configured to determine a first baseline value of dissolved oxygen in a fluid and determine a second baseline value of a total oxygen output in the fluid. The processing circuitry is also configured to receive, from a first sensor, a first signal indicative of an amount of dissolved oxygen in the fluid and receive, from a second sensor, a second signal indicative of the output of the fluid. The processing circuitry is configured to determine a risk of developing acute kidney injury (AKI) based at least in part on the first baseline value, the second baseline value, the first signal, and the second signal.

Abstract: An example device includes processing circuitry configured to receive, from an oxygen sensor, an ambient air signal indicative of an oxygen partial pressure of ambient air. The processing circuitry is further configured to receive, from an atmospheric pressure sensor, an atmospheric pressure sensor signal indicative of atmospheric pressure. The processing circuitry is configured to determine, based on the atmospheric pressure sensor signal, an oxygen partial pressure of the ambient air, determine, based at least in part on the oxygen partial pressure of the ambient air and the ambient air signal, the one or more calibration parameters, and calibrate, based on the one or more calibration parameters, the oxygen sensor. The calibrated oxygen sensor may be used to, for example, determine the oxygen content of urine of a patient to monitor renal function of the patient.

Abstract: In one example, the disclosure relates to a catheter system comprising an elongated body defining a lumen. The elongated body comprising a proximal portion and a distal portion. An anchoring member is positioned on the proximal portion of the elongated body. The anchoring member configured to anchor the proximal portion of the elongated body to a patient. The catheter system includes one or more sensors positioned on the elongated body. The one or more sensors are configured to sense a parameter of a fluid within the lumen of the elongated body. The catheter system includes memory positioned on the elongated body, the memory configured to store patient-specific information.

Abstract: In one example, the disclosure relates to a medical device system comprising an elongated body defining a lumen where the elongated body comprising a proximal portion and a distal portion. A sensor coupled to the elongated body where the sensor comprises a first ultrasonic sensor configured to transmit a first ultrasonic signal in a first direction through a fluid flowing distally within the lumen. The sensor comprising a second ultrasonic sensor configured to transmit a second ultrasonic signal in a second direction through the fluid flowing distally within the lumen where the second ultrasonic sensor may be positioned on the elongated body proximal to the first ultrasonic sensor. The first ultrasonic sensor is configured to receive the second ultrasonic signal transmitted through the fluid flowing in the lumen. The second ultrasonic sensor is configured to receive the first ultrasonic sound transmitted through the fluid flowing in the lumen.

Abstract: In one example, the disclosure relates to a system comprising an elongated body defining a lumen where the elongated body comprising a proximal portion and a distal portion. An anchoring member may be positioned on the proximal portion of the elongated body. The system further comprising a sensor located on the elongated body where the sensor may be configured to sense at least one flow parameter of a fluid within the lumen. Processing circuitry configured to determine at least one of a density parameter or a temperature parameter of the fluid in the lumen based on the sensed at least one flow parameter of the fluid.

Abstract: In some examples, a catheter includes an elongated body defining an injection lumen, a drainage lumen, and an inflation lumen. The elongated body includes an anchoring member positioned on a proximal portion of the elongated body. A sensor is positioned on a distal portion of the elongated body or distal to a distal end of the elongated body. The medical device includes an active valve positioned in or about the drainage lumen The active valve is configured to move between a closed state in which, when a proximal end of the elongated body is positioned in a bladder of a patient, the active valve is configured to retain fluid in the bladder, and an open state in which the active valve enables drainage of fluid from the bladder via the drainage lumen.

Abstract: In one example of the description, a device may have an elongated body defining a lumen. The elongated body may have a proximal portion and a distal portion. An anchoring member may be positioned on the proximal portion of the elongated body. A first temperature sensor may sense a first temperature of a fluid at a first location in the lumen. A second temperature sensor may sense a second temperature of the fluid at a second location in the lumen. The first location may be proximal to the second location. A heating member may be located proximal to the second temperature sensor. The heating member may heat the fluid within the lumen.