Patents by Inventor David J. Powell

David J. Powell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mouse aspartic secretase-2(mASP-2)
    Patent number: 6361975
    Abstract: mASP-2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for screening for compounds that either agonize or antagonize mASP-2. Such compounds are expected to be useful in treatment of human diseases, including, but not limited to: Alzheimer's disease, cancer and prohormone processing.
    Type: Grant
    Filed: November 15, 2000
    Date of Patent: March 26, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Gary Christie, Xiaotong Li, David J. Powell, Yuan Zhu
  • YfiI pseudouridine synthase
    Patent number: 6361965
    Abstract: The invention provides YfiI pseudouridine synthase polypeptides and polynucleotides enconding YfiI pseudouridine synthase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing YfiI pseudouridine synthase polypeptides to screen for antibaterial compound.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: March 26, 2002
    Assignee: SmithKline Beecham Corporation
    Inventor: David J. Powell
  • Mouse aspartic secretase-1 (mASP1)
    Patent number: 6358725
    Abstract: Mouse mASP1 polypeptides and polynucleotides and method for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for screening for compounds that either agonize or antagonize mouse mASP1. Such compounds are expected to be useful in treatment of human diseases, including, but not limited to: Alzheimer's disease, cancer, and prohormone processing.
    Type: Grant
    Filed: July 25, 2001
    Date of Patent: March 19, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Gary Christie, Xiaotong Li, David J. Powell, Yuan Zhu
  • ASP2
    Patent number: 6319689
    Abstract: ASP2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ASP2 polypeptides and polynucleotides in the design of protocols for the treatment of Alzheimer's Disease, cancer, and prohormone processing, among others, and diagnostic assays for such conditions.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: November 20, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: David J Powell, Conrad G Chapman, Kay Murphy, Trudi S Smith
  • Yfil pseudouridine synthase
    Patent number: 6312932
    Abstract: The invention provides YfiI pseudouridine synthase polypeptides and polynucleotides encoding YfiI pseudouridine synthase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing YfiI pseudouridine synthase polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: November 6, 2001
    Assignee: SmithKline Beecham Corporation
    Inventor: David J. Powell
  • Mouse aspartic secretase-1 (mASP1)
    Patent number: 6291223
    Abstract: Mouse mASP1 polypeptides and polynucleotides and method for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for screening for compounds that either agonize or antagonize mouse mASP1. Such compounds are expected to be useful in treatment of human diseases, including, but not limited to: Alzheimer's disease, cancer, and prohormone processing.
    Type: Grant
    Filed: November 21, 2000
    Date of Patent: September 18, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Gary Christie, Xiaotong Li, David J. Powell, Yuan Zhu
  • ASP1
    Patent number: 6162630
    Abstract: ASP1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ASP1 polypeptides and polynucleotides in the design of protocols for the treatment of Alzheimers's Disease, cancer, and melanoma, among others, and diagnostic assays for such conditions.
    Type: Grant
    Filed: November 4, 1999
    Date of Patent: December 19, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: David J Powell, Christopher Southan, Conrad G Chapman, Joanne R Evans
  • Yfii pseudouridine synthase
    Patent number: 6110723
    Abstract: The invention provides YfiI pseudouridine synthase polypeptides and polynucleotides encoding YfiI pseudouridine synthase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing YfiI pseudouridine synthase polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: August 29, 2000
    Assignee: SmithKline Beecham Corporation
    Inventor: David J. Powell
  • ASP1
    Patent number: 6025180
    Abstract: ASP1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ASP1 polypeptides and polynucleotides in the design of protocols for the treatment of Alzheimers's Disease, cancer, and melanoma, among others, and diagnostic assays for such conditions.
    Type: Grant
    Filed: October 6, 1997
    Date of Patent: February 15, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: David J Powell, Christopher Southan, Conrad G Chapman, Joanne R Evans
  • Waistband pouch
    Patent number: 4444342
    Abstract: A detachable waistband pouch having a generally rectangular shape and a top opening which is selectively closable, a casing along the top front edge of the pouch and containing inside thereof an elastic strip to cause a gathering of the top edge of the pouch, a casing along the top edge of the back of the pouch, and a spring clip adapted to be retained in the casing on the back of the pouch with a portion of the clip outside of the pouch adapted to be fastened to the waistband of clothing. The pouch of this invention may be used to carry any small articles such as keys, golf balls, etc.
    Type: Grant
    Filed: January 28, 1983
    Date of Patent: April 24, 1984
    Inventor: David J. Powell