Patents by Inventor David J. Stone
David J. Stone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20040043928Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: August 1, 2002Publication date: March 4, 2004Inventors: Ramesh Kekuda, Charles E. Miller, Meera Patturajan, Carol E. A. Pena, Daniel K. Rieger, Richard A. Shimkets, Bryan D. Zerhusen, Li Li, Weizhen Ji, Muralidhara Padigaru, Stacie J. Casman, Edward Z. Voss, Ferenc L. Boldog, Linda Gorman, Mario W. Leite, Corine A.M. Vernet, David W. Anderson, Xiaojia Sasha Guo, Mei Zhong, Valerie Gerlach, Luca Rastelli, Tord Hjalt, Kimberly A. Spytek, Shlomit R. Edinger, Karen Ellerman, Uriel M. Malyankar, John R. MacDougall, David J. Stone, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess, Kumud Majumder, Adam R. Wolenc, Glennda Smithson, Jason C. Baumgartner
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Publication number: 20040043929Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: January 3, 2003Publication date: March 4, 2004Inventors: David W. Anderson, Robert A. Ballinger, Jason C. Baumgartner, Catherine E. Burgess, Stacie J. Casman, John S. Chant, Constance Berghs, Esha A. Gangolli, Shlomit R. Edinger, Karen Ellerman, Katarzyna Furtak, Valerie Gerlach, Jennifer A. Gilbert, Erik Gunther, Linda Gorman, Xiaojia Sasha Guo, Weizhen Ji, Li Li, Xiaohong Liu, Charles E. Miller, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, Luca Rastelli, John R. MacDougall, Vishnu Mishra, Carol E.A. Pena, Steven K. Spaderna, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Suresh G. Shenoy, Tatiana Ort, Raymond J. Taupier, Velizar T. Tchernev, Corine A.M. Vernet, Adam R. Wolenc, Bryan D. Zerhusen, Mei Zhong
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Publication number: 20040038223Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: October 1, 2002Publication date: February 26, 2004Inventors: Glennda Smithson, Isabelle Millet, John A. Peyman, Ramesh Kekuda, Jingfang Ju, Li Li, Xiaojia (Sasha) Guo, Meera Patturajan, Kimberly A. Spytek, Shlomit R. Edinger, Karen Ellerman, Uriel M. Malyankar, Tatiana Ort, Linda Gorman, Bryan D. Zerhusen, David W. Anderson, Mei Zhong, Elina Catterton, Weizhen Ji, Charles E. Miller, Luca Rastelli, David J. Stone, Carol E. A. Pena, Suresh G. Shenoy, Richard A. Shimkets, Mark E. Rothenberg, Martin D. Leach, Michele L. Agee, Constance Berghs, Vincent A. DiPippo, Andrew Eisen, Esha A. Gangolli, Daniel K. Rieger, Steven K. Spaderna
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Publication number: 20040038230Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: November 4, 2002Publication date: February 26, 2004Inventors: John P. Alsobrook, David W. Anderson, Ferenc L. Boldog, Catherine E. Burgess, John S. Chant, Andrei Chapoval, Amitabha Chaudhuri, Shlomit R. Edinger, Andrew Eisen, Esha A. Gangolli, Valerie Gerlach, Xiaojia Sasha Guo, Weizhen Ji, Nikolai V. Khramtsov, Mario W. Leite, Li Li, Peter S. Mezes, Isabelle Millet, Chean Eng Ooi, Tatiana Ort, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Luca Rastelli, Daniel K. Rieger, Kerry E. Quinn Senger, Glennda Smithson, Steven K. Spaderna, Kimberly A. Spytek, David J. Stone, Nancy Twomlow, Corine A.M. Vernet, Edward Z. Voss, Bryan D. Zerhusen, Mei Zhong
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Publication number: 20040033971Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention farther discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: December 19, 2001Publication date: February 19, 2004Inventors: Esha A. Gangolli, Meera Patturajan, Corine A.M. Vernet, Uriel M. Malyankar, Ramesh Kekuda, David J. Stone, David Anderson, Richard A. Shimkets, Catherine E. Burgess, Bryan D. Zerhusen, Xiaohong Liu, Kimberly A. Spytek, Stacie J. Casman, Ference L. Boldog, Glennda Smithson, Li Li, Weizhen Ji, John R. MacDougall
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Publication number: 20040033491Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: December 10, 2001Publication date: February 19, 2004Inventors: John P. Alsobrook, David W. Anderson, Catherine E. Burgess, Ferenc L. Boldog, Stacie J. Casman, Steven D. Colman, Shlomit R. Edinger, Karen Ellerman, Valerie Gerlach, Linda Gorman, William M. Grosse, Xiaojia Sasha Guo, John L. Herrmann, Ramesh Kekuda, Denise M. Lepley, Li Li, John R. MacDougall, Isabelle Millet, Carol E. A. Pena, John A. Peyman, Luca Rastelli, Daniel K. Rieger, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Velizar T. Tchernev, Corine A.M. Vernet, Edward Z. Voss, Bryan D. Zerhusen, Haihong Zhong, Mei Zhong
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Publication number: 20040029226Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: March 6, 2003Publication date: February 12, 2004Inventors: John Alsobrook, David W. Anderson, Ferenc L. Boldog, Catherine E. Burgess, Ammitabha Chaudhuri, Steven D. Colman, Shlomit R. Edinger, Seth Ettenberg, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, Xiaojia Sasha Guo, Ramesh Kekuda, Li Li, Timothy Z. MacLachlan, Uriel M. Malyankar, Peter S. Mezes, Charles E. Miller, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, John A. Peyman, Xiaozhong Qian, Luca Rastelli, Daniel K. Rieger, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Sujatha Sukumaran, Corine A.M. Vernet, Edward Z. Voss, Mei Zhong
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Publication number: 20040030110Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases.Type: ApplicationFiled: April 2, 2002Publication date: February 12, 2004Inventors: Xiaojia (Sasha) Guo, Ramesh Kekuda, Charles E. Miller, Uriel M. Malyankar, Kimberly A. Spytek, Meera Patturajan, Xiaohong Liu, Vladimir Y. Gusev, Li Li, Corine A.M. Vernet, Bryan D. Zerhusen, Linda Gorman, Suresh G. Shenoy, Carol E. A. Pena, Glennda Smithson, Catherine E. Burgess, Valerie Gerlach, Muralidhara Padigaru, Richard A. Shimkets, Esha A. Gangolli, Raymond J. Taupier, Stacie J. Casman, Weizhen Ji, David W. Anderson, Mario W. Leite, Luca Rastelli, Shlomit R. Edinger, David J. Stone, John R. MacDougall, Mark E. Rothenberg, Ann Mazur, Isabelle Millet, John A. Peyman, Karen Ellerman
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Publication number: 20040029222Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: August 14, 2002Publication date: February 12, 2004Inventors: Shlomit R. Edinger, John R. MacDougall, Isabelle Millet, Karen Ellerman, David J. Stone, Valerie Gerlach, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Danier K. Rieger, Catherine E. Burgess, Stacie J. Casman, Kimberly A. Spytek, Ference L. Boldog, Li Li, Muralidhara Padigaru, Vishnu Mishra, Meera Patturajan, Suresh G. Shenoy, Luca Rastelli, Velizar T. Tchernev, Corine A.M. Vernet, Bryan D. Zerhusen, Uriel M. Malyankar, Xiaojia (Sasha) Guo, Charles E. Miller, Esha A. Gangolli, Michael Grosse
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Publication number: 20040029140Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: July 16, 2003Publication date: February 12, 2004Inventors: David W. Anderson, Catherine E. Burgess, Stacie J. Casman, Linda Gorman, Weizhen Ji, Ramesh Kekuda, Li Li, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Suresh G. Shenoy, Richard A. Shimkets, David J. Stone, Raymond J. Taupier
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Publication number: 20040030096Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: August 1, 2002Publication date: February 12, 2004Inventors: Linda Gorman, Bryan D. Zerhusen, Shlomit R. Edinger, Muralidhara Padigaru, Xiaojia (Sasha) Guo, Ramesh Kekuda, Mei Zhong, Meera Patturajan, Charles E. Miller, Weizhen Ji, Carol E. A. Pena, Catherine E. Burgess, Paul Sciore, David J. Stone, Raymond J. Taupier, Stacie J. Casman, Mark E. Rothenberg, Uriel M. Malyankar, Ferenc L. Boldog
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Publication number: 20040029150Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: March 31, 2003Publication date: February 12, 2004Inventors: John Alsobrook, David Anderson, Ferenc Boldog, Catherine Burgess, Stacie Casman, Shlomit R. Edinger, Valerie Gerlach, William Grosse, Xiaojia Guo, Vladimir Gusev, Weizhen Ji, William LaRochelle, Denise Lepley, Li Li, Xiaohong Liu, John R. MacDougall, Uriel M. Malyankar, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, John A. Peyman, Luca Rastelli, Daniel Rieger, Mark E. Rothenberg, Richard Shimkets, David J. Stone, Raymond Taupier, Corine Vernet, Bryan Zerhusen
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Publication number: 20040029116Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: March 1, 2002Publication date: February 12, 2004Inventors: Shlomit R. Edinger, John R. MacDougall, Isabelle Millet, Karen Ellerman, David J. Stone, Valerie Gerlach, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess, Stacie J. Casman, Kimberly A. Spytek, Ferenc L. Boldog, Li Li, Muralidhara Padigaru, Vishnu Mishra, Meera Patturajan, Suresh G. Shenoy, Luca Rastelli, Velizar T. Tchernev, Corine A.M. Vernet, Bryan D. Zerhusen, Uriel M. Malyankar, Xiaojia Guo, Charles E. Miller, Esha A. Gangolli
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Publication number: 20040029789Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: July 2, 2002Publication date: February 12, 2004Inventors: David W. Anderson, Constance Berghs, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, Elina Catterton, Shlomit R. Edinger, Andrew Eisen, Karen Ellerman, Valerie Gerlach, Linda Gorman, Xiaojia Sasha Guo, Michael E. Jeffers, Ramesh Kekuda, Li Li, Uriel M. Malyankar, Charles E. Miller, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Luca Rastelli, Suresh G. Shenoy, Richard A. Shimkets, Steven K. Spaderna, Kimberly A. Spytek, David J. Stone, Raymond J. Taupier, Corine A.M. Vernet, Edward Z. Voss, Mei Zhong
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Publication number: 20040018970Abstract: Disclosed are novel polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.Type: ApplicationFiled: March 27, 2002Publication date: January 29, 2004Inventors: Richard A. Shimkets, Meera Patturajan, Corine A.M. Vernet, Stacie J. Casman, Uriel M. Malyankar, Suresh G. Shenoy, Kimberly A. Spytek, Esha A. Gangolli, Charles E. Miller, Ferenc L. Boldog, Li Li, Raymond J. Taupier, Ramesh Kekuda, Glennda Smithson, Bryan D. Zerhusen, Xiaohong Liu, Steven D. Colman, Velizar T. Tchernev, Jingsheng Si, Shlomit R. Edinger, David J. Stone, Paul Sciore, Isabelle Millet, Mark E. Rothenberg
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Publication number: 20040018196Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: January 11, 2002Publication date: January 29, 2004Inventors: Peter D. Mezes, Luca Rastelli, John L. Herrmann, John R. MacDougall, Haihong Zhong, Stacie J. Casman, Ferenc L. Boldog, Richard A. Shimkets, Linda Gorman, Andrew J. Eisen, Steven K. Spaderna, Corine A.M. Vernet, Constance Berghs, Kimberly A. Spytek, Vincent A. DiPippo, Bryan D. Zerhusen, John A. Peyman, Karen Ellerman, David J. Stone, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess, Shlomit R. Edinger
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Publication number: 20040009480Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: June 3, 2002Publication date: January 15, 2004Inventors: David W. Anderson, Jason C. Baumgartner, Ferenc L. Boldog, Stacie J. Casman, Shlomit R. Edinger, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, Xiaojia Sasha Guo, Tord Hjalt, Ramesh Kekuda, Li Li, John R. MacDougall, Uriel M. Malyankar, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Luca Rastelli, Richard A. Shimkets, David J. Stone, Kimberly A. Spytek, Corine A.M. Vernet, Edward Z. Voss, Bryan D. Zerhusen
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Publication number: 20040009907Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: February 25, 2002Publication date: January 15, 2004Inventors: John P. Alsobrook, David W. Anderson, Robert A. Ballinger, Ference L. Boldog, Catherine E. Burgess, Stacie J. Casman, Karen Ellerman, Esha A. Gangolli, Valerie Gerlach, Jennifer A. Gilbert, Linda Gorman, Xiaojia (Sasha) Guo, Vladimir Y. Gusev, Ramesh Kekuda, Li Li, Xiaohong Liu, Uriel M. Malyankar, Charles E. Miller, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, John A. Peyman, Luca Rastelli, Suresh G. Shenoy, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Raymond J. Taupier, Velizar T. Tchernev, Corine A.M. Vernet, Bryan D. Zerhusen
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Publication number: 20040005557Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: January 16, 2002Publication date: January 8, 2004Inventors: Muralidhara Padigaru, John P. Alsobrook, Steven D. Colman, Kimberly A. Spytek, Ferenc L. Boldog, Corine A.M. Vernet, Li Li, Suresh G. Shenoy, Stacie J. Casman, Xiaojia (Sasha) Guo, Shlomit R. Edinger, John R. MacDougall, Uriel M. Malyankar, Meera Patturajan, Richard A. Shimkets, Carol E. A. Pena, Velizar T. Tchernev, Bryan D. Zerhusen, Isabelle Millet, Charles E. Miller, Denise M. Lepley, Glennda Smithson, Jason C. Baumgartner, John L. Herrmann, John A. Peyman, Linda Gorman, Peter D. Mezes, Ramesh Kekuda, Raymond J. Taupier, Valerie Gerlach, William M. Grosse, Xiaohong Liu, Karen Ellerman, Mark Rothenberg, David J. Stone, Catherine E. Burgess
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Publication number: 20040005558Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: January 18, 2002Publication date: January 8, 2004Inventors: David W. Anderson, Catherine E. Burgess, Stacie J. Casman, Steven D. Colman, Shlomit R. Edinger, Karen Ellerman, Valerie Gerlach, Erik Gunther, Ramesh Kekuda, John R. MacDougall, Fuad Mehraban, Meera Patturajan, Mark Rothenberg, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Corine A.M. Vernet, Bryan D. Zerhusen