Abstract: A simulation acceleration system is provided. The system includes a simulation accelerator that receives compiled code of a design that includes register transfer level (RTL) components and testbench components. The compiled code includes instructions for simulating behaviors of the design. The simulation accelerator schedules the instructions to be executed by multiple processors based on simulation events occurring at different simulation timesteps. The simulation events are determined according to the executed instructions. The simulation accelerator captures trace data generated by the execution of the scheduled instructions and provides the captured trace data.

Abstract: The present invention relates to ocular compositions for the controlled release of a therapeutic agent. The ocular composition comprises at least 20% w/w of a therapeutic agent; 5 to 75% w/w of a photopolymerizable composition selected from the group consisting of fragments or monomers of polyalkylene glycol mono-acrylate, polyalkylene glycol diacrylate, polyalkylene glycol methacrylate and polyalkylene glycol dimethacrylate, and mixtures, copolymers, and block copolymers thereof; 0.1 to 40% w/w of a biodegradable polymer selected from the group consisting of lactide/glycolide copolymer (including poly(lactide-co-glycolide) (PLGA)), poly (L-lactide) (PLA), polyhydroxyalkanoates, including polyhydroxybutyrate, polyglycolic acid (PGA), polycaprolactone (PCL), poly (DL-lactide) (PDL), poly (D-lactide), lactide/caprolactone copolymer, poly-L-lactide-co-caprolactone (PLC) and mixtures, copolymers, and block copolymers thereof; and a photoinitiator.

Abstract: A community wind turbine cellular system (CWTC system) is disclosed. The CWTC system is configured to provide community-based cellular communication, on a temporary or permanent basis. One or more turbine blades of the CWTC system are configured with an omni-directional radio frequency (RF) antenna suitable for receiving and transmitting mobile communication data to cellular devices. These omni-directional RF antenna have an uninterrupted wired connection that passes from the antenna to an antenna radio within the system's nacelle. More particularly, each RF antenna in a turbine blade is connected, via a wired connection, to a corresponding slip ring within the nacelle of the cellular wind turbine. Each slip ring is connected to the antenna radio via a wired connection. In this manner, each RF antenna maintains a wired connection to the antenna radio, even as the turbine blades are rotating.

Abstract: The present disclosure pertains to an in vitro method for the diagnostic classification of cancer based on the biological state of specific genomic sites. The disclosure provides a method that allows for a classification of a tumour sample obtained from a patient by analysing a multitude, preferably genome wide, collection of gene sites, combining the biological state of the analysed gene sites into a biological state pattern and comparing with pre-determined biological state patterns pertaining to different cancer types or tumour species. The disclosure is in particular useful for classifying cancer e.g. of the central nervous system, such as brain tumour samples and tumours of the spinal cord, since these are characterized by a large variety of distinct tumour species which have different prognostic values and require a developed treatment regime for each species in the clinical context. However, other cancers could similarly profit from the disclosure, for example sarcomas.

Abstract: This disclosure is directed to allocation of one or more radio bands to a user equipment (UE) for establishing a radio link with a radio node (e.g., eNodeB or gNodeB). The radio bands may include a shared band, such as citizens band radio service (CBRS), a primary licensed band, such as the B66 band, and/or an unlicensed band, such as B46 band. A radio communications system may consider a variety of parameters associated with the distance of a UE from a radio node, signal strength of a signal from the UE, the services requested by the UE, and/or spectral availability of the each of the radio bands to determine which radio band(s) to allocate to the UE. In some cases, the radio band allocated to a UE may be dynamically changed by the radio communications system as conditions related to the UE and/or the mobile network change.

Abstract: The present disclosure relates to a smoking substitute system and particularly, although not exclusively, to a smoking substitute device. The smoking substitute device is adapted to operate in a smoking operation while receiving power from an external power source. The smoking substitute device in particular comprises a rechargeable battery and a port to receive power for charging the rechargeable battery, wherein the device is adapted to operate while receiving power from the port.

Abstract: Disclosed are systems, methods, and media for using a secure dataloading system for updating an aerospace system. The secure dataloading system includes a communications module that is configured to communicatively couple the secure dataloading system to the aerospace system. The secure dataloading system also includes a processor that is configured a to access a software repository storing a secure software update having a unique hash ID to provide a copy of the secure software update to the aerospace system via the communications module. The processor can be configured to use a blockchain to validate the unique hash ID of the software update and, upon validation of the unique hash ID, install the secure software update on the aerospace system.

Abstract: The present disclosure relates to a computer-implemented method for cancer diagnosis, comprising: a) selectively sequencing polymers of a biological sample according to at least one target gene site by translocating the polymers through nanopores of a nanopore sequencing system, including: (i) analyzing an initial nucleotide sequence of a first polymer of the biological sample while the first polymer is translocating through a nanopore of the nanopore sequencing system to determine whether the initial nucleotide sequence corresponds to the at least one target gene site; and (ii) continuing the sequencing of the first polymer to obtain measurement data of the first polymer only if the initial nucleotide sequence of the first polymer corresponds to the at least one target gene site: b) determining, based on the measurement data, a biological state of a nucleotide sequence of the first polymer corresponding to the at least one target gene site; and c) classifying a cancer using a classification algorithm based o

Abstract: An aerosol delivery device includes a first aerosol generator to generate a first aerosol from a first aerosol precursor and to introduce the first aerosol into a first fluid flow pathway, and a second aerosol generator to generate a second aerosol from a second aerosol precursor and to introduce the second aerosol into a second fluid flow pathway. The first aerosol is sized for pulmonary penetration. The second aerosol generator comprises a Venturi aperture to dispense and aerosolise the second aerosol precursor in the second aerosol generator. The second aerosol precursor is a liquid, and the second aerosol is sized to inhibit pulmonary penetration. The second aerosol is transmissible within a mammalian oral and/or nasal cavity. The second aerosol includes an active component for activating at least one of: one or more taste receptors in the oral cavity and one or more olfactory receptors in the nasal cavity.

Abstract: A mass and/or mobility spectrometer comprising: an ion source enclosure for housing an ion source: a vacuum chamber; a pumping block between the ion source enclosure and vacuum chamber; and a shield for protecting a surface of the ion source enclosure; wherein the shield has a first portion configured to mount to a upstream side of the pumping block so as to secure the shield at a location in which a second portion of the shield covers an internal surface of the ion source enclosure.

Abstract: The invention relates to an electronic smoking device (100) with an atomizer/liquid reservoir portion (114) and to an atomizer/liquid reservoir portion (114). In order to facilitate refilling a liquid reservoir (134) of the atomizer/liquid reservoir portion (114), the atomizer/liquid reservoir portion (114) comprises a docking valve (146) for docking a source of liquid (148) to be stored in the liquid reservoir (134), and a liquid duct (156) that is adapted to receive liquid (172) from the docking valve (146) and that opens into the refillable liquid reservoir (134) at a predetermined distance (A) to the docking valve (146).

Abstract: An aerosol delivery device includes a first aerosol generator to generate a first aerosol from a first aerosol precursor and to introduce the first aerosol into a first fluid flow pathway, and a second aerosol generator to generate a second aerosol from a second aerosol precursor and to introduce the second aerosol into a second fluid flow pathway. The first aerosol is sized for pulmonary penetration. The second aerosol generator comprises a Venturi aperture to dispense and aerosolise the second aerosol precursor in the second aerosol generator. The second aerosol precursor is a liquid, and the second aerosol is sized to inhibit pulmonary penetration. The second aerosol is transmissible within a mammalian oral and/or nasal cavity. The second aerosol includes an active component for activating at least one of: one or more taste receptors in the oral cavity and one or more olfactory receptors in the nasal cavity.

Abstract: There is disclosed a method of enabling sign-ins by a terminal in communication with a server located at a different location when compared to the terminal, the method comprising: in response to capturing a mobile device identifier displayed by a mobile device, determining whether or not the displayed mobile device identifier matches a visual identifier based on the captured identifier; upon determining that the displayed mobile device identifier matches the visual identifier, transmitting first sign-in information from the terminal to the server; in response to receiving a server identifier transmitted from the server, wherein the server identifier is generated by the server in response to receipt of the first sign-in information, displaying the received server identifier; and in response to receiving second sign-in information transmitted from the server, displaying a notification indicating a sign-in.

Abstract: This disclosure describes techniques that enable individual antenna arrays of a base station node to transmit digital information via a plurality of frequency bands. More specifically, a remote radio unit (RRU) may include a first set of antenna arrays and a second set of antenna arrays. Each set of antenna arrays comprise antenna elements that are configured for use with different frequency bands. In this way, the RRU, via the first and second sets of antenna arrays, may be configured for simultaneous use with different frequency bands.

Abstract: There is disclosed an aerosol delivery system comprising: an aerosol-generating device comprising: a device housing having an open-ended heating chamber configured to receive a carrier cartridge; a heater element disposed within the heating chamber and configured to receive at least a first end of a carrier cartridge, said heating element operable to heat a carrier substrate of a carrier unit of said carrier cartridge to cause release of an aerosol-forming precursor therefrom to generate an aerosol when gas is passed through the carrier cartridge; and a carrier cartridge comprising a carrier unit, said carrier unit comprising a carrier substrate configured to hold an aerosol-forming precursor comprising a nicotine-containing and/or flavoured fluid, gel, wax, or powder. Also disclosed are a carrier cartridge, carrier unit, methods of manufacturing one or more components of said system, and a kit-of-parts for assembling the system.

Abstract: Exemplary embodiments pertain to a solution containing carbon black. The solution may be applied to a membrane filter of a microbial enumeration system as a post-rinse solution (i.e., after the membrane filter is rinsed with the sample of interest). The solution may reduce or suppress background autofluorescence, thereby improving detection and enumeration of colony forming units (CFUs) or other microbiological entities. The solution may be used in connection with a method for performing sample preparation for a microbial enumeration system. The carbon black solution may be manufactured according to a manufacturing process detailed herein.

Abstract: An apparatus includes an illumination assembly. The illumination assembly includes a plurality of light sources arranged in a two-dimensional array. The light sources are positioned within the array to provide overlapping illumination fields. The plurality of light sources provide illumination within a UV-A spectrum of wavelengths to thereby provide photocleaving within a fluid containment assembly.

Abstract: A sealant smoothing tool for smoothing sealant in a gap between two aircraft parts is disclosed including a main body having a base surface for abutting sliding along a top surface of the aircraft parts, a spatula holder for holding a spatula, the spatula holder being configured to movably mount the spatula relative to the main body, and a resilient biasing member, configured to provide a biasing against the spatula or the spatula holder, such that the spatula supplies a biasing force to the sealant. An aircraft having two parts sealed by the sealant smoothing tool, a kit of parts including a sealant smoothing tool and one or more spatulas, and a method of smoothing sealant to seal a gap between two aircraft parts are also disclosed.

Abstract: The present disclosure provides an aerosol forming article comprising an aerosol forming article comprising a cavity for receiving an aerosol former, an infrared heater in thermal communication with the cavity, where the infrared heater comprises at least one heating element in a halogen-filled enclosure and where the enclosure at least partly circumscribes the cavity. There is also provided an aerosol delivery article comprising: a cavity for receiving an aerosol former, the cavity having a perimeter, and an IR heater comprising at least one heating element for heating the aerosol former. A major portion of the perimeter of the cavity faces away from the heating element(s).

Abstract: The invention relates to an electronic smoking device (100) with an atomizer/liquid reservoir portion (114) and to an atomizer/liquid reservoir portion (114). In order to facilitate refilling a liquid reservoir (134) of the atomizer/liquid reservoir portion (114), the atomizer/liquid reservoir portion (114) comprises a docking valve (146) for docking a source of liquid (148) to be stored in the liquid reservoir (134), and a liquid duct (156) that is adapted to receive liquid (172) from the docking valve (146) and that opens into the refillable liquid reservoir (134) at a predetermined distance (A) to the docking valve (146).