Patents by Inventor David Kaplan

David Kaplan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7123171
    Abstract: RFID system components, such as readers and tags, communicate by transmitting and receiving a wave that conveys a bit stream. Informing signals, such as special bits, are inserted in the stream between words. An informing signal indicates whether a certain word is the last word in the stream or not.
    Type: Grant
    Filed: February 6, 2006
    Date of Patent: October 17, 2006
    Assignee: Impinj, Inc.
    Inventors: David Kaplan, Christopher J. Diorio
  • Publication number: 20060187094
    Abstract: RFID system components, such as readers and tags, communicate by transmitting and receiving a wave that conveys a bit stream. Informing signals, such as special bits, are inserted in the stream between words. An informing signal indicates whether a certain word is the last word in the stream or not.
    Type: Application
    Filed: February 6, 2006
    Publication date: August 24, 2006
    Applicant: IMPINJ, Inc.
    Inventors: David Kaplan, Christopher Diorio
  • Publication number: 20060159837
    Abstract: The present invention is directed to a method for forming an inorganic coating on a protein template. The method comprises contacting the template with an anionic polymer interface followed by an inorganic material for a sufficient period of time to allow mineralization of the inorganic material thus forming an inorganic coating on the template. Preferably, the coating is aligned.
    Type: Application
    Filed: November 29, 2005
    Publication date: July 20, 2006
    Applicant: Tufts University
    Inventors: David Kaplan, Chunmei Li
  • Patent number: 7030786
    Abstract: RFID system components, such as readers and tags, communicate by transmitting and receiving a wave that conveys a bit stream. Informing signals, such as special bits, are inserted in the stream between words. An informing signal indicates whether a certain word is the last word in the stream or not.
    Type: Grant
    Filed: January 7, 2005
    Date of Patent: April 18, 2006
    Assignee: Impinj, Inc.
    Inventors: David Kaplan, Christopher J. Diorio
  • Publication number: 20050270189
    Abstract: RFID system components, such as readers and tags, communicate by transmitting and receiving a wave that conveys a bit stream. Informing signals, such as special bits, are inserted in the stream between words. An informing signal indicates whether a certain word is the last word in the stream or not.
    Type: Application
    Filed: January 7, 2005
    Publication date: December 8, 2005
    Applicant: IMPINJ, INC.
    Inventors: David Kaplan, Christopher Diorio
  • Publication number: 20050260706
    Abstract: The present invention provides an all-aqueous process and composition for production of silk biomaterials, e.g., fibers, films, foams and mats. In the process, at least one biocompatible polymer, such as poly(ethylene oxide) (PEO) (a well-documented biocompatible material), was blended with the silk protein prior to processing e.g., electrospinning. We discovered that this step avoids problems associated with conformational transitions of fibroin during solubilization and reprocessing from aqueous solution which lead to embrittled materials. Moreover, the process avoids the use of organic solvents that can pose problems when the processed biomaterials are exposed to cells in vitro or in vivo.
    Type: Application
    Filed: December 23, 2004
    Publication date: November 24, 2005
    Applicants: Tufts University, Massachusetts Institute of Technology
    Inventors: David Kaplan, Hyoung-Joon Jin, Gregory Rutledge, Sergey Fridrikh
  • Publication number: 20050227219
    Abstract: A method is provided for growing young cells that reduces and/or reverses age-related processes that would otherwise occur in those cells, and also compositions for growing cells in such a method.
    Type: Application
    Filed: December 22, 2004
    Publication date: October 13, 2005
    Inventors: Vladimir Volloch, David Kaplan
  • Publication number: 20050090641
    Abstract: The invention features miniblock polymers containing solubilizing blocks and folding blocks, wherein the miniblock polymers in solution can self-fabricate to form materials having a long-range order. Also disclosed are rigid well-fabricated materials and methods of using these materials.
    Type: Application
    Filed: October 2, 2002
    Publication date: April 28, 2005
    Inventors: Regina Valluzzi, David Kaplan
  • Publication number: 20050089552
    Abstract: The present invention provides a novel silk-fiber-based matrix having a wire-rope geometry for use in producing a ligament or tendon, particularly an anterior cruciate ligament, ex vivo for implantation into a recipient in need thereof. The invention further provides the novel silk-fiber-based matrix which is seeded with pluripotent cells that proliferate and differentiate on the matrix to form a ligament or tendon ex vivo. Also disclosed is a bioengineered ligament comprising the silk-fiber-based matrix seeded with pluripotent cells that proliferate and differentiate on the matrix to form the ligament or tendon. A method for producing a ligament or tendon ex vivo comprising the novel silk-fiber-based matrix is also disclosed.
    Type: Application
    Filed: November 16, 2004
    Publication date: April 28, 2005
    Applicants: Tissue Regeneration, Inc., Trustees of Tufts College
    Inventors: Gregory Altman, David Kaplan, Rebecca Horan, David Horan
  • Publication number: 20050003462
    Abstract: The present invention relates to methods of staining cells for flow cytometry, using catalyzed reporter deposition and amplification staining. A catalyzed reporter deposition or an analyte dependent enzyme activation system is described for detecting and/or quantitating an analyte of interest in a cell by flow cytometry. Also described are compositions for use in catalyzed reporter deposition methods that can be used to reduce background staining, and thereby enhance peak signal separation between histograms obtained from cells stained with control immunoglobulin versus cells stained with immunoglobulin specific for an analyte of interest, in catalyzed deposition methods.
    Type: Application
    Filed: July 29, 2004
    Publication date: January 6, 2005
    Inventor: David Kaplan
  • Patent number: 6817738
    Abstract: A medical film illuminator includes a frame having a translucent panel. A film gripper is attached directly to the translucent panel and the translucent panel is attached to the frame using magnets that engage the frame. Thus, the translucent panel can be easily removed to service the interior of the frame. Moreover, the spacing between the gripper and panel is established during manufacture and does not change, thus ensuring that gripping tension on film that is slid between the gripper and panel remains constant during the life of the illuminator.
    Type: Grant
    Filed: May 6, 2002
    Date of Patent: November 16, 2004
    Assignee: Wolf X-Ray Corporation
    Inventors: William P. Winters, David Kaplan
  • Patent number: 6772169
    Abstract: A system, a method and an apparatus are provided for the wireless monitoring and management of computer systems, networks, software systems or databases on a portable and/or handheld device which may monitor, update, and fix the system from any location and at any time. More specifically, the system, the method and the apparatus provide for the wireless monitoring and management of such systems by formatting information on a handheld screen of a wireless device, automatically wrapping portions of information for browsing on wireless devices, displaying information in a graph or other format on a wireless device, and/or auto-scaling of graphs on a wireless device.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: August 3, 2004
    Assignee: Expand Beyond Corporation
    Inventor: Ari David Kaplan
  • Patent number: 6566469
    Abstract: A method for polymerization of substituted ethylene monomers in an enzyme-mediated process is disclosed. The reaction proceeds under mild conditions with a wide variety of monomers, and is capable of producing stereoregular polymers. In certain embodiments, no organic solvent is necessary.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: May 20, 2003
    Assignees: Trustees of Tufts College, Rohm & Haas Company, Polytechnic Institute of New York
    Inventors: David Kaplan, Graham Swift, Richard A. Gross, Bhanu Kalra
  • Publication number: 20020110800
    Abstract: The invention provides a means of identifying compounds which modulate SHP biological activity in neurons and which thus regulate neuronal cell death.
    Type: Application
    Filed: August 1, 2001
    Publication date: August 15, 2002
    Applicant: McGill University
    Inventors: David Kaplan, H. Nick Marsh
  • Publication number: 20020095427
    Abstract: A system, a method and an apparatus are provided for the wireless monitoring and management of computer systems, networks, software systems or databases on a portable and/or handheld device which may monitor, update, and fix the system from any location and at any time. More specifically, the system, the method and the apparatus provide for the wireless monitoring and management of such systems by formatting information on a handheld screen of a wireless device, automatically wrapping portions of information for browsing on wireless devices, displaying information in a graph or other format on a wireless device, and/or auto-scaling of graphs on a wireless device.
    Type: Application
    Filed: September 27, 2001
    Publication date: July 18, 2002
    Inventor: Ari David Kaplan
  • Publication number: 20020062151
    Abstract: The present invention provides a method for producing an anterior cruciate ligament ex vivo. The method comprises seeding pluripotent stem cells in a three dimensional matrix, anchoring the seeded matrix by attachment to two anchors, and culturing the cells within the matrix under conditions appropriate for cell growth and regeneration, while subjecting the matrix to one or more mechanical forces via movement of one or both of the attached anchors. Bone marrow stromal cells are preferably used as the pluripotent cells in the method. Suitable matrix materials are materials to which cells can adhere, such as a gel made from collagen type I. Suitable anchor materials are materials to which the matrix can attach, such as Goinopra coral and also demineralized bone. Some examples of tissue which can be produced include other ligaments in the body (hand, wrist, elbow, knee), tendon, cartilage, bone, muscle, and blood vessels.
    Type: Application
    Filed: September 10, 2001
    Publication date: May 23, 2002
    Inventors: Gregory Altman, David Kaplan, Gordana Vunjak-Novakovic, Ivan Martin
  • Publication number: 20020009747
    Abstract: The invention provides assays for modulators of neuronal apoptosis. The assays include measurement of the levels of p53, Bad, Bax, p21, p27 and phosphorylated Rb in neurons which have been induced to undergo apoptosis.
    Type: Application
    Filed: August 25, 1997
    Publication date: January 24, 2002
    Inventors: FREDA DIANE MILLER, RAQUEL SILVIA ALOYZ, DAVID KAPLAN
  • Patent number: 6287340
    Abstract: The present invention provides a method for producing an anterior cruciate ligament ex vivo. The method comprises seeding pluripotent stem cells in a three dimensional matrix, anchoring the seeded matrix by attachment to two anchors, and culturing the cells within the matrix under conditions appropriate for cell growth and regeneration, while subjecting the matrix to one or more mechanical forces via movement of one or both of the attached anchors. Bone marrow stromal cells are preferably used as the pluripotent cells in the method. Suitable matrix materials are materials to which cells can adhere, such as a gel made from collagen type I. Suitable anchor materials are materials to which the matrix can attach, such as Goinopra coral and also demineralized bone. Optimally, the mechanical forces to which the matrix is subjected mimic mechanical stimuli experienced by an anterior cruciate ligament in vivo.
    Type: Grant
    Filed: May 14, 1999
    Date of Patent: September 11, 2001
    Assignees: Trustees of Tufts College, Massachusetts Institute of Technology
    Inventors: Gregory Altman, David Kaplan, Gordana Vunjak-Novakovic, Ivan Martin
  • Patent number: 6071709
    Abstract: The present invention relates to a complex comprising nerve growth factor (NGF) and trk proto-oncogene protein and a complex comprising neurotrophic factors, NT-3 or BDNF, and trkB proto-oncogene protein. The present invention also relates to methods for detecting the presence of NGF, NT-3 or BDNF neurotrophic factors and trk and trk-related proto-oncogene receptors. The present invention further relates to methods that may be used in diagnostics and therapeutics for neurodegenerative diseases such as Alzheimer's and Huntington's by detecting complexes comprising NGF or NGF related neurotrophic factors bound to the product of the tyrosine kinase trk or related trk proto-oncogene family member.
    Type: Grant
    Filed: May 29, 1992
    Date of Patent: June 6, 2000
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Luis F. Parada, Dan Soppet, David Kaplan, Dionisio Martin-Zanca
  • Patent number: 5981743
    Abstract: An oligomer composed of a carbohydrate head group and an oligomer chain is disclosed. Methods for increasing the oligomerization rates of lactones and cyclic carbonates are also disclosed.
    Type: Grant
    Filed: March 28, 1997
    Date of Patent: November 9, 1999
    Assignee: University of Massachusetts
    Inventors: Richard A. Gross, Kirpal Bisht, David Kaplan, Graham Swift, Fang Deng