Patents by Inventor David Karl

David Karl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11971407
    Abstract: An in vitro method is disclosed for detecting an antibody to p53 (anti-p53 antibody) in a sample, the method comprising: incubating a sample to be analyzed with a p53 capture antigen and a p53 detection antigen, whereby a complex comprising the p53 capture antigen, the anti-p53 antibody and the p53 detection antigen is formed, separating the complex formed from unbound detection antigen and measuring the complex obtained via the detection antigen comprised therein, thereby detecting the anti-p53 antibody comprised in the sample.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: April 30, 2024
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Herbert Andres, Johann Karl, Ursula Kunert, David Morgenstern, Nina Meissler, Marion Niessner, Magdalena Swiatek-de Lange
  • Patent number: 11964589
    Abstract: An electrified vehicle includes a storage compartment positioned forward of a vehicle passenger cabin and accessible by opening a vehicle hood, a thermally conductive plate or heat exchanger in contact with a bottom surface of the storage compartment and having an associated conduit configured for circulating a working fluid from a vehicle cooling system, and a valve operable to control flow of the working fluid through the conduit. The storage compartment may be filled with a cooling medium, such as ice or dry ice, to provide enhanced cooling during high-demand operation or charging of the vehicle, such as when operating in a performance/track mode, towing a trailer, or in other extreme use scenarios. The valve may be controlled so that the working fluid bypasses the conduit when the storage compartment is used for cargo and/or enhanced cooling is not desired.
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: April 23, 2024
    Assignee: Ford Global Technologies, LLC
    Inventors: Patrick Gordon Collins, David Michael Horan, Thomas Karl Rothermel, Jacob Gregory Powers
  • Publication number: 20240122510
    Abstract: Blood sample optimization systems and methods are described that reduce or eliminate contaminates in collected blood samples, which in turn reduces or eliminates false positive readings in blood cultures or other testing of collected blood samples. A blood sample optimization system can include a blood sequestration device located between a patient needle and a sample needle. The blood sequestration device can include a sequestration chamber for sequestering an initial, potentially contaminated aliquot of blood, and may further include a sampling channel that bypasses the sequestration chamber to convey likely uncontaminated blood between the patient needle and the sample needle after the initial aliquot of blood is sequestered in the sequestration chamber.
    Type: Application
    Filed: May 15, 2023
    Publication date: April 18, 2024
    Applicant: KURIN, INC.
    Inventors: Bobby E. ROGERS, Gino KANG, David Karl STROUP, Jonas Dean COCHRAN, Arthur DEPTALA, John DETLOFF, Lonnie POGUE, Brian MACOWSKI
  • Patent number: 11958728
    Abstract: A system is provided for use with an insulated boom section of a bucket truck. The system includes a source of high volume and pressure, dry air; one or more interior air diffusers connected to the source of high volume and pressure, dry air to direct the air into an interior of the insulated boom section. One or more exterior air diffusers connected to the source of high volume and pressure, dry air direct the air to along an exterior surface of the insulated boom section. A method is also provided for cleaning or drying both the interior and exterior surfaces simultaneously of an insulated boom section of the boom of a bucket truck. The boom of a bucket truck is further provided in another aspect that includes at least one insulated boom section, a source of high volume and pressure, dry air, one or more interior air diffusers and one or more exterior air diffusers. A pre-heating air heater may be removably mounted into the boom.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: April 16, 2024
    Assignee: Quanta Associates, L.P.
    Inventors: David Karl Wabnegger, Daniel Neil O'Connell, David James Ball, Robert Wayne Palmer, Jody Milton Greer, Raymond Henry Jodoin
  • Publication number: 20240116738
    Abstract: A crane with at least one main carrier which is moveable and a crane trolley which is mounted on the at least one main carrier for movement, a winch carrier being fastened to the crane trolley, and a load suspension apparatus which is moveable up and down in the vertical direction by cables hanging on the winch carrier, the load suspension apparatus having gripping tools for releasably gripping a load. The crane has at least one camera and at least one control stand for a crane driver, and the control stand has at least one screen. At least one assistance graphic can be superimposed on the at least one screen onto the display of the image recorded instantaneously by the camera, as an aid for the crane driver for orienting the load suspension apparatus and/or the gripping tool of the load suspension apparatus relative to the load to be gripped.
    Type: Application
    Filed: October 4, 2023
    Publication date: April 11, 2024
    Applicant: Hans Künz GmbH
    Inventors: David MOOSBRUGGER, Johannes Karl EBERHARTER, Lukas FINK
  • Patent number: 11946938
    Abstract: The present disclosure demonstrates a method for predicting the risk of stroke of a subject and a method for improving the prediction accuracy of a clinical stroke risk score. The methods are based on the determination of the amount of Angiopoietin-2 (Ang-2) and/or the amount of Insulin-like growth factor-binding protein 7 (IGFBP7) in a sample from a subject. Moreover, disclose is the use of i) the biomarker Ang-2 and/or the biomarker IGFBP7, and/or ii) at least one detection agent that specifically binds to Ang-2 and/or at least one detection agent that specifically binds to IGFBP7 in a sample from a subject for predicting the risk of stroke of said subject.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: April 2, 2024
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Ursula-Henrike Wienhues-Thelen, Johann Karl, Peter Kastner, Vinzent Rolny, Andre Ziegler, David Conen
  • Patent number: 11826527
    Abstract: A safety needle assembly includes a housing and a cannula hub connected within a side wall of the housing, a needle connected to the cannula and extending from the cannula hub outward from a proximal end of the housing, and a spring connected with the housing. The assembly includes a barrel connected with the spring and at least partially contained within the housing to least partially cover the cannula hub. The barrel is configured for moving, sliding, traveling, activating, relocating, or transitioning from a first mode in which the barrel is securely retracted and locked at least partially within the housing and the needle extends through an aperture of the barrel and the proximal end of the housing, to a second mode in which the barrel extends from the proximal end and beyond the needle.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: November 28, 2023
    Assignee: KURIN, INC.
    Inventors: Bobby E. Rogers, David Karl Stroup
  • Publication number: 20230314113
    Abstract: An implosion shield of ballistic fabric adapted to mount so as to surround an implosion sleeve or dead-end on a power line. The implosion shield may be wrapped or formed as an envelope or tent including one piece and folded around the implosion sleeve or dead-end and secured with fasteners. A method of installing the implosion cover may include installing an implosion sleeve or dead-end on a power line, and then installing the implosion shield around the implosion sleeve or dead-end, by wrapping the implosion shield around the implosion sleeve or dead-end, or by securing an envelope implosion shield over the implosion sleeve or dead-end, or by draping the shield over the implosion sleeve or dead-end, or by mounting the shield on a frame over the implosion sleeve or dead-end, then detonating the implosion sleeve or dead-end. The implosion shield attenuates shock, pressure and sound waves from the detonation.
    Type: Application
    Filed: June 8, 2023
    Publication date: October 5, 2023
    Inventors: David Karl WABNEGGER, Daniel Neil O'CONNELL, Mark Douglas FERRARI, Benjamin James HARVEY
  • Patent number: 11760485
    Abstract: A remotely controlled unmanned aerial device for use in proximity or in contact with high voltage powerlines, includes an unmanned aerial vehicle and an electrically conductive shield forming part of or operatively coupled to so as to encapsulate the unmanned aerial vehicle. When in the presence of a high voltage powerline, the unmanned aerial vehicle either when bonded-on or within the corresponding magnetic fields of the powerline, so as to transfer the powerline potential in whole or in part to the unmanned aerial vehicle, electrically energizes the conductive shield around the unmanned aerial vehicle while leaving components of the unmanned aerial vehicle within the shield substantially electrically unaffected by the voltage potential.
    Type: Grant
    Filed: May 23, 2022
    Date of Patent: September 19, 2023
    Assignee: Quanta Associates, L.P.
    Inventors: David Karl Wabnegger, Daniel Neil O'Connell
  • Patent number: 11749915
    Abstract: A grounding clamp includes a safety lock-out which locks the operation of the clamp in the absence of a cooperating hot-stick. The lock-out employs a clutch which prevents the translation of the clamping members relative to one another until the clutch is disengaged. The cooperating hot-stick is required for the disengagement of the clutch.
    Type: Grant
    Filed: July 18, 2022
    Date of Patent: September 5, 2023
    Assignee: Quanta Associates, L.P.
    Inventors: Phillip Howard Quaedvlieg, David Karl Wabnegger, Janos Csaba Toth, Daniel Neil O'Connell
  • Patent number: 11744494
    Abstract: Blood sample optimization systems and methods are described that reduce or eliminate contaminates in collected blood samples, which in turn reduces or eliminates false positive readings in blood cultures or other testing of collected blood samples. A blood sample optimization system can include a blood sequestration device located between a patient needle and a sample needle. The blood sequestration device can include a sequestration chamber for sequestering an initial, potentially contaminated aliquot of blood, and may further include a sampling channel that bypasses the sequestration chamber to convey likely uncontaminated blood between the patient needle and the sample needle after the initial aliquot of blood is sequestered in the sequestration chamber.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: September 5, 2023
    Assignee: KURIN, INC.
    Inventors: Bobby E. Rogers, Gino Kang, David Karl Stroup, Jonas Dean Cochran, Arthur Deptala, John Detloff, Lonnie Pogue, Brian Macowski
  • Patent number: 11713954
    Abstract: An implosion shield of ballistic fabric adapted to mount so as to surround an implosion sleeve or dead-end on a power line. The implosion shield may be wrapped or formed as an envelope or tent including one piece and folded around the implosion sleeve or dead-end and secured with fasteners. A method of installing the implosion cover may include installing an implosion sleeve or dead-end on a power line, and then installing the implosion shield around the implosion sleeve or dead-end, by wrapping the implosion shield around the implosion sleeve or dead-end, or by securing an envelope implosion shield over the implosion sleeve or dead-end, or by draping the shield over the implosion sleeve or dead-end, or by mounting the shield on a frame over the implosion sleeve or dead-end, then detonating the implosion sleeve or dead-end. The implosion shield attenuates shock, pressure and sound waves from the detonation.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: August 1, 2023
    Assignee: Quanta Associates, L.P.
    Inventors: David Karl Wabnegger, Daniel Neil O'Connell, Mark Douglas Ferrari, Benjamin James Harvey
  • Publication number: 20230117979
    Abstract: Load-bearing apparatus/systems for location in the vicinity of energized power lines are provided. The apparatus includes a base member. The base member has an upper layer and a backing surface layer. An uppermost surface of the upper layer is adapted to support on it at least power line workers and/or related stringing equipment. At least the uppermost surface of the upper layer is adapted to be electrically conductive. Methods for forming the apparatus are also provided.
    Type: Application
    Filed: December 15, 2022
    Publication date: April 20, 2023
    Inventors: David James BALL, Jody Milton GREER, David Karl WABNEGGER, Robert Wayne PALMER
  • Publication number: 20230116910
    Abstract: Blood sample optimization systems and methods are described that reduce or eliminate contaminates in collected blood samples, which in turn reduces or eliminates false positive readings in blood cultures or other testing of collected blood samples. A blood sample optimization system can include a blood sequestration device located between a patient needle and a sample needle. The blood sequestration device can include a sequestration chamber for sequestering an initial, potentially contaminated aliquot of blood, and may further include a sampling channel that bypasses the sequestration chamber to convey likely uncontaminated blood between the patient needle and the sample needle after the initial aliquot of blood is sequestered in the sequestration chamber.
    Type: Application
    Filed: April 26, 2022
    Publication date: April 13, 2023
    Inventors: Bobby E. ROGERS, Gino KANG, David Karl STROUP, Jonas Dean COCHRAN, Arthur DEPTALA, John DETLOFF, Lonnie POGUE, Brian MACOWSKI
  • Patent number: 11617525
    Abstract: A blood sequestration device includes an inlet path, an outlet path, a sequestration chamber, and a sampling channel. The sequestration chamber is connected with the inlet path by a junction and is configured to receive a first portion of blood through the inlet path. The sequestration chamber has a vent that allows air to be displaced by the first portion of blood, the junction being configured to inhibit a return to the inlet path of any of the first portion of blood received by the sequestration chamber. The sampling channel is connected between the inlet path and the outlet path, and configured to convey subsequent amounts of blood between the inlet path and the outlet path after the first amount of blood is received by the sequestration chamber.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: April 4, 2023
    Assignee: KURIN, INC.
    Inventors: Bobby E. Rogers, Gino Kang, David Karl Stroup, Jonas Dean Cochran, Arthur Deptala, John Detloff, Lonnie Pogue, Brian Macowski, Kevin Nason
  • Patent number: 11597273
    Abstract: An automotive axle includes a housing including gears and a bath lubricating the gears, the bath including gear oil and about 0.1 to 5 wt. % secondary alcohol ethoxylate based on total weight of the bath such that during automotive operation at temperatures less than a threshold, reverse micelles form to trap air bubbles in the bath, emulsifying the bath, and at temperatures greater than the threshold, the reverse micelles dissipate.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: March 7, 2023
    Assignee: Ford Global Technologies, LLC
    Inventors: Hiroko Ohtani, Kevin Richard John Ellwood, David Karl Bidner, Arup Kumar Gangopadhyay, Mathew John Fast, Phillip Bonkoski
  • Publication number: 20230052348
    Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.
    Type: Application
    Filed: October 14, 2021
    Publication date: February 16, 2023
    Applicant: AMGEN INC.
    Inventors: Sean P BROWN, David Karl BEDKE, Michael R. DEGRAFFENREID, Jiasheng FU, Zhinghong LI, Felix GONZALEZ LOPEZ DE TURISO, Ana GONZALEZ BUENROSTRO, Michael W. GRIBBLE JR., Michael G. JOHNSON, Todd J. KOHN, Kexue LI, Yunxiao LI, Mike Elias LIZARZABURU, Yosup REW, Joshua TAYGERLY, Yingcai WANG, Xuelei YAN, Ming YU, Jiang ZHU, Manuel ZANCANELLA, Xian Yun JIAO, Liusheng ZHU, Xianghong WANG, Julio C. MEDINA, Jason A. DUQUETTE, Jonathan B. HOUZE, Marc VIMOLRATANA, Mario G. CARDOZO, Alan C. CHENG
  • Patent number: 11578795
    Abstract: Methods and systems are provided for regulating the temperature of rear axle lubrication oil. In one example, a rear axle coolant system may include a coolant loop with a plurality of valves and sensors, regulating the coolant flow in heat exchange relationship with an exhaust gas heat recovery and storage system to deliver warm coolant to a rear axle heat exchanger to warm the rear axle lubrication oil. The method may regulate the components of the rear axle coolant system through a controller, receiving sensor input from the components of the coolant system.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: February 14, 2023
    Assignee: Ford Global Technologies, LLC
    Inventors: Cary Cole, Sunil Katragadda, Phillip Bonkoski, David Karl Bidner, Michael Levin, Colby Jason Buckman, Danrich Henry Demitroff, Amey Y. Karnik, Furqan Shaikh
  • Patent number: 11563313
    Abstract: The present invention relates to replacing conductors in a high-voltage power transfer system. The method provides, for example, a method for maintaining sections of electrically conductive phases in a three-phase power conductor line, wherein the three phases are parallel and spaced apart in an ordered sequence. The phases are strung between support structures and supported above the ground. Maintenance work, which include replacement or repair, is performed on sections of the three phases without interrupting a power load in any one of the three phases and without transposing the relative positions of the phases out of their ordered sequence.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: January 24, 2023
    Assignee: Quanta Associates, L.P.
    Inventors: Daniel Neil O'Connell, David Karl Wabnegger, Phillip Howard Quaedvlieg, Robert Wayne Palmer
  • Patent number: 11545817
    Abstract: Load-bearing apparatus/systems for location in the vicinity of energized power lines are provided. The apparatus includes a base member. The base member has an upper layer and a backing surface layer. An uppermost surface of the upper layer is adapted to support on it at least power line workers and/or related stringing equipment. At least the uppermost surface of the upper layer is adapted to be electrically conductive. Methods for forming the apparatus are also provided.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: January 3, 2023
    Assignee: Quanta Associates, L.P.
    Inventors: David James Ball, Jody Milton Greer, David Karl Wabnegger, Robert Wayne Palmer