Patents by Inventor David Karl
David Karl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11971407Abstract: An in vitro method is disclosed for detecting an antibody to p53 (anti-p53 antibody) in a sample, the method comprising: incubating a sample to be analyzed with a p53 capture antigen and a p53 detection antigen, whereby a complex comprising the p53 capture antigen, the anti-p53 antibody and the p53 detection antigen is formed, separating the complex formed from unbound detection antigen and measuring the complex obtained via the detection antigen comprised therein, thereby detecting the anti-p53 antibody comprised in the sample.Type: GrantFiled: April 27, 2022Date of Patent: April 30, 2024Assignee: Roche Diagnostics Operations, Inc.Inventors: Herbert Andres, Johann Karl, Ursula Kunert, David Morgenstern, Nina Meissler, Marion Niessner, Magdalena Swiatek-de Lange
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Patent number: 11964589Abstract: An electrified vehicle includes a storage compartment positioned forward of a vehicle passenger cabin and accessible by opening a vehicle hood, a thermally conductive plate or heat exchanger in contact with a bottom surface of the storage compartment and having an associated conduit configured for circulating a working fluid from a vehicle cooling system, and a valve operable to control flow of the working fluid through the conduit. The storage compartment may be filled with a cooling medium, such as ice or dry ice, to provide enhanced cooling during high-demand operation or charging of the vehicle, such as when operating in a performance/track mode, towing a trailer, or in other extreme use scenarios. The valve may be controlled so that the working fluid bypasses the conduit when the storage compartment is used for cargo and/or enhanced cooling is not desired.Type: GrantFiled: November 10, 2021Date of Patent: April 23, 2024Assignee: Ford Global Technologies, LLCInventors: Patrick Gordon Collins, David Michael Horan, Thomas Karl Rothermel, Jacob Gregory Powers
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Publication number: 20240122510Abstract: Blood sample optimization systems and methods are described that reduce or eliminate contaminates in collected blood samples, which in turn reduces or eliminates false positive readings in blood cultures or other testing of collected blood samples. A blood sample optimization system can include a blood sequestration device located between a patient needle and a sample needle. The blood sequestration device can include a sequestration chamber for sequestering an initial, potentially contaminated aliquot of blood, and may further include a sampling channel that bypasses the sequestration chamber to convey likely uncontaminated blood between the patient needle and the sample needle after the initial aliquot of blood is sequestered in the sequestration chamber.Type: ApplicationFiled: May 15, 2023Publication date: April 18, 2024Applicant: KURIN, INC.Inventors: Bobby E. ROGERS, Gino KANG, David Karl STROUP, Jonas Dean COCHRAN, Arthur DEPTALA, John DETLOFF, Lonnie POGUE, Brian MACOWSKI
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Patent number: 11958728Abstract: A system is provided for use with an insulated boom section of a bucket truck. The system includes a source of high volume and pressure, dry air; one or more interior air diffusers connected to the source of high volume and pressure, dry air to direct the air into an interior of the insulated boom section. One or more exterior air diffusers connected to the source of high volume and pressure, dry air direct the air to along an exterior surface of the insulated boom section. A method is also provided for cleaning or drying both the interior and exterior surfaces simultaneously of an insulated boom section of the boom of a bucket truck. The boom of a bucket truck is further provided in another aspect that includes at least one insulated boom section, a source of high volume and pressure, dry air, one or more interior air diffusers and one or more exterior air diffusers. A pre-heating air heater may be removably mounted into the boom.Type: GrantFiled: October 18, 2018Date of Patent: April 16, 2024Assignee: Quanta Associates, L.P.Inventors: David Karl Wabnegger, Daniel Neil O'Connell, David James Ball, Robert Wayne Palmer, Jody Milton Greer, Raymond Henry Jodoin
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Publication number: 20240116738Abstract: A crane with at least one main carrier which is moveable and a crane trolley which is mounted on the at least one main carrier for movement, a winch carrier being fastened to the crane trolley, and a load suspension apparatus which is moveable up and down in the vertical direction by cables hanging on the winch carrier, the load suspension apparatus having gripping tools for releasably gripping a load. The crane has at least one camera and at least one control stand for a crane driver, and the control stand has at least one screen. At least one assistance graphic can be superimposed on the at least one screen onto the display of the image recorded instantaneously by the camera, as an aid for the crane driver for orienting the load suspension apparatus and/or the gripping tool of the load suspension apparatus relative to the load to be gripped.Type: ApplicationFiled: October 4, 2023Publication date: April 11, 2024Applicant: Hans Künz GmbHInventors: David MOOSBRUGGER, Johannes Karl EBERHARTER, Lukas FINK
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Patent number: 11946938Abstract: The present disclosure demonstrates a method for predicting the risk of stroke of a subject and a method for improving the prediction accuracy of a clinical stroke risk score. The methods are based on the determination of the amount of Angiopoietin-2 (Ang-2) and/or the amount of Insulin-like growth factor-binding protein 7 (IGFBP7) in a sample from a subject. Moreover, disclose is the use of i) the biomarker Ang-2 and/or the biomarker IGFBP7, and/or ii) at least one detection agent that specifically binds to Ang-2 and/or at least one detection agent that specifically binds to IGFBP7 in a sample from a subject for predicting the risk of stroke of said subject.Type: GrantFiled: June 12, 2020Date of Patent: April 2, 2024Assignee: Roche Diagnostics Operations, Inc.Inventors: Ursula-Henrike Wienhues-Thelen, Johann Karl, Peter Kastner, Vinzent Rolny, Andre Ziegler, David Conen
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Patent number: 11826527Abstract: A safety needle assembly includes a housing and a cannula hub connected within a side wall of the housing, a needle connected to the cannula and extending from the cannula hub outward from a proximal end of the housing, and a spring connected with the housing. The assembly includes a barrel connected with the spring and at least partially contained within the housing to least partially cover the cannula hub. The barrel is configured for moving, sliding, traveling, activating, relocating, or transitioning from a first mode in which the barrel is securely retracted and locked at least partially within the housing and the needle extends through an aperture of the barrel and the proximal end of the housing, to a second mode in which the barrel extends from the proximal end and beyond the needle.Type: GrantFiled: July 25, 2018Date of Patent: November 28, 2023Assignee: KURIN, INC.Inventors: Bobby E. Rogers, David Karl Stroup
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Publication number: 20230314113Abstract: An implosion shield of ballistic fabric adapted to mount so as to surround an implosion sleeve or dead-end on a power line. The implosion shield may be wrapped or formed as an envelope or tent including one piece and folded around the implosion sleeve or dead-end and secured with fasteners. A method of installing the implosion cover may include installing an implosion sleeve or dead-end on a power line, and then installing the implosion shield around the implosion sleeve or dead-end, by wrapping the implosion shield around the implosion sleeve or dead-end, or by securing an envelope implosion shield over the implosion sleeve or dead-end, or by draping the shield over the implosion sleeve or dead-end, or by mounting the shield on a frame over the implosion sleeve or dead-end, then detonating the implosion sleeve or dead-end. The implosion shield attenuates shock, pressure and sound waves from the detonation.Type: ApplicationFiled: June 8, 2023Publication date: October 5, 2023Inventors: David Karl WABNEGGER, Daniel Neil O'CONNELL, Mark Douglas FERRARI, Benjamin James HARVEY
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Patent number: 11760485Abstract: A remotely controlled unmanned aerial device for use in proximity or in contact with high voltage powerlines, includes an unmanned aerial vehicle and an electrically conductive shield forming part of or operatively coupled to so as to encapsulate the unmanned aerial vehicle. When in the presence of a high voltage powerline, the unmanned aerial vehicle either when bonded-on or within the corresponding magnetic fields of the powerline, so as to transfer the powerline potential in whole or in part to the unmanned aerial vehicle, electrically energizes the conductive shield around the unmanned aerial vehicle while leaving components of the unmanned aerial vehicle within the shield substantially electrically unaffected by the voltage potential.Type: GrantFiled: May 23, 2022Date of Patent: September 19, 2023Assignee: Quanta Associates, L.P.Inventors: David Karl Wabnegger, Daniel Neil O'Connell
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Patent number: 11749915Abstract: A grounding clamp includes a safety lock-out which locks the operation of the clamp in the absence of a cooperating hot-stick. The lock-out employs a clutch which prevents the translation of the clamping members relative to one another until the clutch is disengaged. The cooperating hot-stick is required for the disengagement of the clutch.Type: GrantFiled: July 18, 2022Date of Patent: September 5, 2023Assignee: Quanta Associates, L.P.Inventors: Phillip Howard Quaedvlieg, David Karl Wabnegger, Janos Csaba Toth, Daniel Neil O'Connell
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Patent number: 11744494Abstract: Blood sample optimization systems and methods are described that reduce or eliminate contaminates in collected blood samples, which in turn reduces or eliminates false positive readings in blood cultures or other testing of collected blood samples. A blood sample optimization system can include a blood sequestration device located between a patient needle and a sample needle. The blood sequestration device can include a sequestration chamber for sequestering an initial, potentially contaminated aliquot of blood, and may further include a sampling channel that bypasses the sequestration chamber to convey likely uncontaminated blood between the patient needle and the sample needle after the initial aliquot of blood is sequestered in the sequestration chamber.Type: GrantFiled: November 10, 2020Date of Patent: September 5, 2023Assignee: KURIN, INC.Inventors: Bobby E. Rogers, Gino Kang, David Karl Stroup, Jonas Dean Cochran, Arthur Deptala, John Detloff, Lonnie Pogue, Brian Macowski
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Patent number: 11713954Abstract: An implosion shield of ballistic fabric adapted to mount so as to surround an implosion sleeve or dead-end on a power line. The implosion shield may be wrapped or formed as an envelope or tent including one piece and folded around the implosion sleeve or dead-end and secured with fasteners. A method of installing the implosion cover may include installing an implosion sleeve or dead-end on a power line, and then installing the implosion shield around the implosion sleeve or dead-end, by wrapping the implosion shield around the implosion sleeve or dead-end, or by securing an envelope implosion shield over the implosion sleeve or dead-end, or by draping the shield over the implosion sleeve or dead-end, or by mounting the shield on a frame over the implosion sleeve or dead-end, then detonating the implosion sleeve or dead-end. The implosion shield attenuates shock, pressure and sound waves from the detonation.Type: GrantFiled: December 18, 2020Date of Patent: August 1, 2023Assignee: Quanta Associates, L.P.Inventors: David Karl Wabnegger, Daniel Neil O'Connell, Mark Douglas Ferrari, Benjamin James Harvey
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Publication number: 20230117979Abstract: Load-bearing apparatus/systems for location in the vicinity of energized power lines are provided. The apparatus includes a base member. The base member has an upper layer and a backing surface layer. An uppermost surface of the upper layer is adapted to support on it at least power line workers and/or related stringing equipment. At least the uppermost surface of the upper layer is adapted to be electrically conductive. Methods for forming the apparatus are also provided.Type: ApplicationFiled: December 15, 2022Publication date: April 20, 2023Inventors: David James BALL, Jody Milton GREER, David Karl WABNEGGER, Robert Wayne PALMER
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Publication number: 20230116910Abstract: Blood sample optimization systems and methods are described that reduce or eliminate contaminates in collected blood samples, which in turn reduces or eliminates false positive readings in blood cultures or other testing of collected blood samples. A blood sample optimization system can include a blood sequestration device located between a patient needle and a sample needle. The blood sequestration device can include a sequestration chamber for sequestering an initial, potentially contaminated aliquot of blood, and may further include a sampling channel that bypasses the sequestration chamber to convey likely uncontaminated blood between the patient needle and the sample needle after the initial aliquot of blood is sequestered in the sequestration chamber.Type: ApplicationFiled: April 26, 2022Publication date: April 13, 2023Inventors: Bobby E. ROGERS, Gino KANG, David Karl STROUP, Jonas Dean COCHRAN, Arthur DEPTALA, John DETLOFF, Lonnie POGUE, Brian MACOWSKI
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Patent number: 11617525Abstract: A blood sequestration device includes an inlet path, an outlet path, a sequestration chamber, and a sampling channel. The sequestration chamber is connected with the inlet path by a junction and is configured to receive a first portion of blood through the inlet path. The sequestration chamber has a vent that allows air to be displaced by the first portion of blood, the junction being configured to inhibit a return to the inlet path of any of the first portion of blood received by the sequestration chamber. The sampling channel is connected between the inlet path and the outlet path, and configured to convey subsequent amounts of blood between the inlet path and the outlet path after the first amount of blood is received by the sequestration chamber.Type: GrantFiled: March 13, 2020Date of Patent: April 4, 2023Assignee: KURIN, INC.Inventors: Bobby E. Rogers, Gino Kang, David Karl Stroup, Jonas Dean Cochran, Arthur Deptala, John Detloff, Lonnie Pogue, Brian Macowski, Kevin Nason
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Patent number: 11597273Abstract: An automotive axle includes a housing including gears and a bath lubricating the gears, the bath including gear oil and about 0.1 to 5 wt. % secondary alcohol ethoxylate based on total weight of the bath such that during automotive operation at temperatures less than a threshold, reverse micelles form to trap air bubbles in the bath, emulsifying the bath, and at temperatures greater than the threshold, the reverse micelles dissipate.Type: GrantFiled: January 8, 2019Date of Patent: March 7, 2023Assignee: Ford Global Technologies, LLCInventors: Hiroko Ohtani, Kevin Richard John Ellwood, David Karl Bidner, Arup Kumar Gangopadhyay, Mathew John Fast, Phillip Bonkoski
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Publication number: 20230052348Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.Type: ApplicationFiled: October 14, 2021Publication date: February 16, 2023Applicant: AMGEN INC.Inventors: Sean P BROWN, David Karl BEDKE, Michael R. DEGRAFFENREID, Jiasheng FU, Zhinghong LI, Felix GONZALEZ LOPEZ DE TURISO, Ana GONZALEZ BUENROSTRO, Michael W. GRIBBLE JR., Michael G. JOHNSON, Todd J. KOHN, Kexue LI, Yunxiao LI, Mike Elias LIZARZABURU, Yosup REW, Joshua TAYGERLY, Yingcai WANG, Xuelei YAN, Ming YU, Jiang ZHU, Manuel ZANCANELLA, Xian Yun JIAO, Liusheng ZHU, Xianghong WANG, Julio C. MEDINA, Jason A. DUQUETTE, Jonathan B. HOUZE, Marc VIMOLRATANA, Mario G. CARDOZO, Alan C. CHENG
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Patent number: 11578795Abstract: Methods and systems are provided for regulating the temperature of rear axle lubrication oil. In one example, a rear axle coolant system may include a coolant loop with a plurality of valves and sensors, regulating the coolant flow in heat exchange relationship with an exhaust gas heat recovery and storage system to deliver warm coolant to a rear axle heat exchanger to warm the rear axle lubrication oil. The method may regulate the components of the rear axle coolant system through a controller, receiving sensor input from the components of the coolant system.Type: GrantFiled: July 11, 2019Date of Patent: February 14, 2023Assignee: Ford Global Technologies, LLCInventors: Cary Cole, Sunil Katragadda, Phillip Bonkoski, David Karl Bidner, Michael Levin, Colby Jason Buckman, Danrich Henry Demitroff, Amey Y. Karnik, Furqan Shaikh
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Patent number: 11563313Abstract: The present invention relates to replacing conductors in a high-voltage power transfer system. The method provides, for example, a method for maintaining sections of electrically conductive phases in a three-phase power conductor line, wherein the three phases are parallel and spaced apart in an ordered sequence. The phases are strung between support structures and supported above the ground. Maintenance work, which include replacement or repair, is performed on sections of the three phases without interrupting a power load in any one of the three phases and without transposing the relative positions of the phases out of their ordered sequence.Type: GrantFiled: May 1, 2020Date of Patent: January 24, 2023Assignee: Quanta Associates, L.P.Inventors: Daniel Neil O'Connell, David Karl Wabnegger, Phillip Howard Quaedvlieg, Robert Wayne Palmer
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Patent number: 11545817Abstract: Load-bearing apparatus/systems for location in the vicinity of energized power lines are provided. The apparatus includes a base member. The base member has an upper layer and a backing surface layer. An uppermost surface of the upper layer is adapted to support on it at least power line workers and/or related stringing equipment. At least the uppermost surface of the upper layer is adapted to be electrically conductive. Methods for forming the apparatus are also provided.Type: GrantFiled: July 26, 2018Date of Patent: January 3, 2023Assignee: Quanta Associates, L.P.Inventors: David James Ball, Jody Milton Greer, David Karl Wabnegger, Robert Wayne Palmer