Patents by Inventor David Knaack

David Knaack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200061233
    Abstract: The present invention relates to water soluble and completely absorbable and/or physiologically degradable hemostatic compositions having a wax or wax-like base effective for tamponade hemostasis of bone or cartilage.
    Type: Application
    Filed: October 30, 2019
    Publication date: February 27, 2020
    Inventors: David KNAACK, John PACIFICO, Marci WIRTZ, Richard L. KRONENTHAL, Frank DO, Aniq DARR
  • Patent number: 10549009
    Abstract: The present invention relates to water soluble and completely absorbable and/or physiologically degradable hemostatic compositions having a wax or wax-like base effective for tamponade hemostasis of bone or cartilage.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: February 4, 2020
    Assignee: Abyrx, Inc.
    Inventors: David Knaack, John Pacifico, Marci Wirtz, Richard L. Kronenthal, Frank Do, Aniq Darr
  • Patent number: 10517985
    Abstract: The present invention relates to water soluble and completely absorbable and/or physiologically degradable hemostatic compositions having a wax or wax-like base effective for tamponade hemostasis of bone or cartilage.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: December 31, 2019
    Assignee: Abyrx, Inc.
    Inventors: David Knaack, John Pacifico, Marci Wirtz, Richard L. Kronenthal, Frank Do, Aniq Darr
  • Patent number: 10328179
    Abstract: An osteoinductive composition, corresponding osteoimplants, and methods for making the osteoinductive composition are disclosed. The osteoinductive composition comprises osteoinductive factors, such as may be extracted from demineralized bone, and a carrier. The osteoinductive composition is prepared by providing demineralized bone, extracting osteoinductive factors from the demineralized bone, and adding the extracted osteoinductive factors to a carrier. Further additives such as bioactive agents may be added to the osteoinductive composition. The carrier and osteoinductive factors may form an osteogenic osteoimplant. The osteoimplant, when implanted in a mammalian body, can induce at the locus of the implant the full developmental cascade of endochondral bone formation including vascularization, mineralization, and bone marrow differentiation. Also, in some embodiments, the osteoinductive composition can be used as a delivery device to administer bioactive agents.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: June 25, 2019
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Keyvan Behnam, David Knaack
  • Patent number: 10322209
    Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: June 18, 2019
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd Boyce, Lawrence A. Shimp
  • Patent number: 10289082
    Abstract: An app store includes a plurality of state machines that describe the function of a product. The system allows a user to select at least one app from this plurality of apps. The user may also customize the state machine represented by the app or parameters thereof. The selected state machine can be translated into a format readable by a semiconductor device in a target platform without requiring the user to generate computer code. The app store can also transact rights to use the app represented by the state machine. The state machine may be executed in a simulation environment, on a reference platform or development board, or on a semiconductor device in an end-user product to facilitate control in accordance with the state machine defined by the state machine.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: May 14, 2019
    Assignee: DANFOSS POWER ELECTRONICS A/S
    Inventors: Ali Husain, Greg Jackson, Chris Knaack, David Stopher
  • Publication number: 20180361014
    Abstract: The present invention relates to water soluble and completely absorbable and/or physiologically degradable hemostatic compositions having a wax or wax-like base effective for tamponade hemostasis of bone or cartilage.
    Type: Application
    Filed: August 7, 2018
    Publication date: December 20, 2018
    Inventors: David Knaack, John Pacifico, Marci Wirtz, Richard L. Kronenthal, Frank Do, Aniq Darr
  • Publication number: 20180344893
    Abstract: The present invention relates to water soluble and completely absorbable and/or physiologically degradable hemostatic compositions having a wax or wax-like base effective for tamponade hemostasis of bone or cartilage.
    Type: Application
    Filed: August 7, 2018
    Publication date: December 6, 2018
    Inventors: David Knaack, John Pacifico, Marci Wirtz, Richard L. Kronenthal, Frank Do, Aniq Darr
  • Patent number: 10080661
    Abstract: An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: September 25, 2018
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Deger C. Tunc, John Winterbottom, David R. Kaes, Todd Boyce, David Knaack, James Russell, Subhabrata Bhattacharyya
  • Publication number: 20180250442
    Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.
    Type: Application
    Filed: May 8, 2018
    Publication date: September 6, 2018
    Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd Boyce, Lawrence A. Shimp
  • Patent number: 9993579
    Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: June 12, 2018
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
  • Publication number: 20170304496
    Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.
    Type: Application
    Filed: July 6, 2017
    Publication date: October 26, 2017
    Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
  • Patent number: 9789223
    Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: October 17, 2017
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
  • Publication number: 20160250025
    Abstract: An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.
    Type: Application
    Filed: May 9, 2016
    Publication date: September 1, 2016
    Inventors: Deger C. Tunc, John Winterbottom, David R. Kaes, Todd Boyce, David Knaack, James Russell, Subhabrata Bhattacharyya
  • Publication number: 20160243284
    Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.
    Type: Application
    Filed: May 2, 2016
    Publication date: August 25, 2016
    Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
  • Patent number: 9333080
    Abstract: An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.
    Type: Grant
    Filed: August 21, 2013
    Date of Patent: May 10, 2016
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Deger C. Tunc, John Winterbottom, David R. Kaes, Todd M. Boyce, David Knaack, James Russell, Subhabrata Bhattacharyya
  • Patent number: 9327052
    Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.
    Type: Grant
    Filed: April 22, 2013
    Date of Patent: May 3, 2016
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: David A. Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
  • Patent number: 9107751
    Abstract: An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.
    Type: Grant
    Filed: January 19, 2007
    Date of Patent: August 18, 2015
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: John Winterbottom, David R. Kaes, Deger C. Tunc, Todd M. Boyce, David Knaack, James Russell, Subhabrata Bhattacharyya
  • Publication number: 20150190547
    Abstract: An osteoinductive composition, corresponding osteoimplants, and methods for making the osteoinductive composition are disclosed. The osteoinductive composition comprises osteoinductive factors, such as may be extracted from demineralized bone, and a carrier. The osteoinductive composition is prepared by providing demineralized bone, extracting osteoinductive factors from the demineralized bone, and adding the extracted osteoinductive factors to a carrier. Further additives such as bioactive agents may be added to the osteoinductive composition. The carrier and osteoinductive factors may form an osteogenic osteoimplant. The osteoimplant, when implanted in a mammalian body, can induce at the locus of the implant the full developmental cascade of endochondral bone formation including vascularization, mineralization, and bone marrow differentiation. Also, in some embodiments, the osteoinductive composition can be used as a delivery device to administer bioactive agents.
    Type: Application
    Filed: March 18, 2015
    Publication date: July 9, 2015
    Inventors: Keyvan Behnam, David Knaack
  • Publication number: 20140275287
    Abstract: The present invention relates to water soluble and completely absorbable and/or physiologically degradable hemostatic compositions having a wax or wax-like base effective for use in tamponade hemostasis of bone or cartilage.
    Type: Application
    Filed: November 1, 2012
    Publication date: September 18, 2014
    Applicant: ABYRX, INC.
    Inventors: David Knaack, John Pacifico, Marci Wirtz, Richard L. Kronenthal, Frank Do, Aniq Darr