Patents by Inventor David Leach

David Leach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260122275
    Abstract: Systems, methods, and apparatuses are described for processing video. Encoded video data may be determined from uncompressed video data. A chrominance component for a portion of the encoded video data may be determined that references another portion of the encoded video data. A luma component of the portion of the encoded video data may be determined to correspond with the luma component of the corresponding portion of the uncompressed video data.
    Type: Application
    Filed: December 16, 2024
    Publication date: April 30, 2026
    Inventors: Douglas BAY, David LEACH
  • Publication number: 20260074628
    Abstract: One example includes a multi-level switching power converter system. The system includes a switch controller configured to generate a plurality of switching signals at a variable frequency. The system also includes a multi-level switching converter comprising a plurality of switches configured to receive the respective switching signals to convert an input voltage to an output voltage. One of the input and output voltages can be an AC voltage. The switch controller can provide the switching signals at the variable frequency. The variable frequency can vary within a fundamental period of the AC voltage. The system further includes a filter coupled to the multi-level switching converter and comprising a saturable inductor.
    Type: Application
    Filed: September 9, 2024
    Publication date: March 12, 2026
    Inventors: MATTHEW HONICKMAN, RUSSEL MARVIN, DAVID LEACH
  • Publication number: 20260074622
    Abstract: One example includes a TAB switching converter that includes a transformer, a first switching stage, a second switching, and a third switching stage to convert between a DC voltage and an AC voltage. Switching nodes of the second and third switching stages can be directly coupled to respective first and second windings of the transformer. The system further includes a switch controller configured to generate switching signals at a variable frequency that varies as a function of a power metric associated with a frequency of the AC voltage, and to provide a variable phase shift between the respective switching signals that control one switch in each of pairs of switches in at least one of the second and third switching stages relative to another one switch in each of the pairs of the respective at least one of the second and third switching stages.
    Type: Application
    Filed: September 9, 2024
    Publication date: March 12, 2026
    Inventors: MATTHEW HONICKMAN, RUSSEL MARVIN, DAVID LEACH
  • Publication number: 20250276085
    Abstract: Provided herein are compositions comprising multi domain peptide (MDP) hydrogels where the peptides that constitute the hydrogel have at least one N6-(1-iminoethyl)-lysine side chain. Also provided are hydrogels that further comprise a STING agonist, an immune checkpoint inhibitor, and/or an anti-cancer therapy. Also provided are methods of using such compositions in the treatment of cancer.
    Type: Application
    Filed: February 14, 2025
    Publication date: September 4, 2025
    Applicants: William Marsh Rice University, The Board of Regents of The University of Texas System, Baylor College of Medicine
    Inventors: Jeffrey HARTGERINK, Andrew G. SIKORA, David LEACH, Jared M. NEWTON, Simon YOUNG
  • Patent number: 12383653
    Abstract: Provided herein are peptide-based hydrogels, or neutral multidomain peptide hydrogel (NMDP), as well as uses thereof. The uses include encapsulating cells to induce quiescence for long-term storage and administering to a subject to induce collagen deposition and macrophage infiltration. The disclosed hydrogel is useful for the preservation of stem cells, including maintaining their quiescence and differentiation potential.
    Type: Grant
    Filed: October 16, 2019
    Date of Patent: August 12, 2025
    Assignee: William Marsh Rice University
    Inventors: Jeffrey Hartgerink, David Leach, Tania Lopez-Silva
  • Patent number: 12271846
    Abstract: A dispatch advisor to assist in selecting operating conditions of a power plant that maximizes operational revenue is described. The dispatch advisor obtains a base load map for operating the power plant to meet base load power demands. The base load map includes a primary base load operating space for attaining target plant power output and efficiency, and an expanded base load portion for attaining higher plant power output and less than optimal efficiency. Both the primary base load operating space and the expanded base load portion associate power output and efficiency values of the power plant that result from a subset of operational parameter values for operating the power plant during base load. The dispatch advisor can transform the flexible base load map into one or more visualizations describing the revenue possibilities associated with operating the power plant based on operating values and attained power output and efficiency.
    Type: Grant
    Filed: November 14, 2023
    Date of Patent: April 8, 2025
    Assignee: GE INFRASTRUCTURE TECHNOLOGY LLC
    Inventors: Ilya Alexandrovich Slobodyanskiy, David Leach, Berardino Pezzella
  • Patent number: 12251449
    Abstract: Provided herein are compositions comprising multi domain peptide (MDP) hydrogels where the peptides that constitute the hydrogel have at least one N6-(1-iminoethyl)-lysine side chain. Also provided are hydrogels that further comprise a STING agonist, an immune checkpoint inhibitor, and/or an anti-cancer therapy. Also provided are methods of using such compositions in the treatment of cancer.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: March 18, 2025
    Assignees: William Marsh Rice University, Baylor College of Medicine, The Board of Regents of The University of Texas System
    Inventors: Jeffrey Hartgerink, Andrew G. Sikora, David Leach, Jared M. Newton, Simon Young
  • Patent number: 12206900
    Abstract: Systems, methods, and apparatuses are described for processing video. Encoded video data may be determined from uncompressed video data. A chrominance component for a portion of the encoded video data may be determined that references another portion of the encoded video data. A luma component of the portion of the encoded video data may be determined to correspond with the luma component of the corresponding portion of the uncompressed video data.
    Type: Grant
    Filed: June 30, 2023
    Date of Patent: January 21, 2025
    Assignee: Comcast Cable Communications, LLC
    Inventors: Douglas Bay, David Leach
  • Patent number: 12158114
    Abstract: A dispatch advisor for operating a power plant having at least one gas turbine with flexibility is described. The dispatch advisor can generate a representation of a flexible base load map for operating the power plant. The representation can include an aggregation of a primary base load operating space and an expanded portion of the base load operating space. The representation offers a range of operating values for operational parameters of the power plant during base load at various base load settings at predetermined ambient conditions and corresponding power output and efficiency values that are attained while operating the power plant at the range of operating values. This offers an operator of the power plant with flexibility in controlling the plant during base load.
    Type: Grant
    Filed: April 29, 2021
    Date of Patent: December 3, 2024
    Assignee: GE INFRASTRUCTURE TECHNOLOGY LLC
    Inventors: Ilya Alexandrovich Slobodyanskiy, David Leach, Berardino Pezzella
  • Publication number: 20240388936
    Abstract: Access devices may receive signals over a network and calculate a frequency spectrum of the received signals. An analyzer system may collect the frequency spectrum data from multiple access devices, and based on the collected data, detect, identify, and locate sources of anomalies in a communication network.
    Type: Application
    Filed: July 24, 2024
    Publication date: November 21, 2024
    Inventors: Lawrence Wolcott, Justin Riggert, David Leach, Thomas Emerson Bach, James Russell, Edward David Monnerat, Todd Szuter, Bryan Thomas
  • Patent number: 12098683
    Abstract: A dispatch advisor for operating a power plant having at least one gas turbine with flexibility is described. The dispatch advisor can generate a representation of a flexible base load map for operating the power plant. The representation can include an aggregation of a primary base load operating space and an expanded portion of the base load operating space. The representation offers a range of operating values for operational parameters of the power plant during base load at various base load settings at predetermined ambient conditions and corresponding power output and efficiency values that are attained while operating the power plant at the range of operating values. This offers an operator of the power plant with flexibility in controlling the plant during base load.
    Type: Grant
    Filed: July 18, 2023
    Date of Patent: September 24, 2024
    Assignee: GE INFRASTRUCTURE TECHNOLOGY LLC
    Inventors: Ilya Alexandrovich Slobodyanskiy, David Leach, Berardino Pezzella
  • Patent number: 12096260
    Abstract: Access devices may receive signals over a network and calculate a frequency spectrum of the received signals. An analyzer system may collect the frequency spectrum data from multiple access devices, and based on the collected data, detect, identify, and locate sources of anomalies in a communication network.
    Type: Grant
    Filed: May 23, 2022
    Date of Patent: September 17, 2024
    Assignee: TiVo Corporation
    Inventors: Lawrence Wolcott, Justin Riggert, David Leach, Thomas Emerson Bach, James Russell, Edward David Monnerat, Todd Szuter, Bryan Thomas
  • Patent number: 11969499
    Abstract: In one aspect, the present disclosure provides for novel compositions of matter comprising multi domain peptide (MDP) hydrogels and cyclic dinucleotides (CDNs). Also disclosed are method of using such compositions in the treatment of cancer, including in particular the treatment of head and neck cancers, such as those resistant to CDN therapy.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: April 30, 2024
    Assignees: William Marsh Rice University, The Board of Regents of The University of Texas System
    Inventors: Simon Young, David Leach, Jeffrey D. Hartgerink
  • Publication number: 20240095623
    Abstract: A dispatch advisor to assist in selecting operating conditions of a power plant that maximizes operational revenue is described. The dispatch advisor obtains a base load map for operating the power plant to meet base load power demands. The base load map includes a primary base load operating space for attaining target plant power output and efficiency, and an expanded base load portion for attaining higher plant power output and less than optimal efficiency. Both the primary base load operating space and the expanded base load portion associate power output and efficiency values of the power plant that result from a subset of operational parameter values for operating the power plant during base load. The dispatch advisor can transform the flexible base load map into one or more visualizations describing the revenue possibilities associated with operating the power plant based on operating values and attained power output and efficiency.
    Type: Application
    Filed: November 14, 2023
    Publication date: March 21, 2024
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: ILYA ALEXANDROVICH SLOBODYANSKIY, DAVID LEACH, BERARDINO PEZZELLA
  • Publication number: 20240080426
    Abstract: Methods and systems for managing content items are described. A content item may be separated into components, such as chroma components, luminance components, and audio components. For more efficient management of the content, including for storage and delivery of the content, the separate components may be stored at different locations. For example, chroma components may be stored on a central server, while luminance and audio components are stored at other locations, such as edge servers, or vice versa, to accommodate network efficiency considerations. When content is delivered to a player, two or more separate streams carrying different content components may be delivered to the player.
    Type: Application
    Filed: June 29, 2023
    Publication date: March 7, 2024
    Inventors: Douglas Bay, David Leach
  • Patent number: 11893525
    Abstract: A dispatch advisor to assist in selecting operating conditions of a power plant that maximizes operational revenue is described. The dispatch advisor obtains a base load map for operating the power plant to meet base load power demands. The base load map includes a primary base load operating space for attaining target plant power output and efficiency, and an expanded base load portion for attaining higher plant power output and less than optimal efficiency. Both the primary base load operating space and the expanded base load portion associate power output and efficiency values of the power plant that result from a subset of operational parameter values for operating the power plant during base load. The dispatch advisor can transform the flexible base load map into one or more visualizations describing the revenue possibilities associated with operating the power plant based on operating values and attained power output and efficiency.
    Type: Grant
    Filed: April 29, 2021
    Date of Patent: February 6, 2024
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Ilya Alexandrovich Slobodyanskiy, David Leach, Berardino Pezzella
  • Publication number: 20240040153
    Abstract: Systems, methods, and apparatuses are described for processing video. Encoded video data may be determined from uncompressed video data. A chrominance component for a portion of the encoded video data may be determined that references another portion of the encoded video data. A luma component of the portion of the encoded video data may be determined to correspond with the luma component of the corresponding portion of the uncompressed video data.
    Type: Application
    Filed: June 30, 2023
    Publication date: February 1, 2024
    Inventors: Douglas Bay, David Leach
  • Publication number: 20230358179
    Abstract: A dispatch advisor for operating a power plant having at least one gas turbine with flexibility is described. The dispatch advisor can generate a representation of a flexible base load map for operating the power plant. The representation can include an aggregation of a primary base load operating space and an expanded portion of the base load operating space. The representation offers a range of operating values for operational parameters of the power plant during base load at various base load settings at predetermined ambient conditions and corresponding power output and efficiency values that are attained while operating the power plant at the range of operating values. This offers an operator of the power plant with flexibility in controlling the plant during base load.
    Type: Application
    Filed: July 18, 2023
    Publication date: November 9, 2023
    Applicant: GE INFRASTRUCTURE TECHNOLOGY LLC
    Inventors: ILYA ALEXANDROVICH SLOBODYANSKIY, DAVID LEACH, BERARDINO PEZZELLA
  • Patent number: 11743439
    Abstract: Methods and systems for managing content items are described. A content item may be separated into components, such as chroma components, luminance components, and audio components. For more efficient management of the content, including for storage and delivery of the content, the separate components may be stored at different locations. For example, chroma components may be stored on a central server, while luminance and audio components are stored at other locations, such as edge servers, or vice versa, to accommodate network efficiency considerations. When content is delivered to a player, two or more separate streams carrying different content components may be delivered to the player.
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: August 29, 2023
    Assignee: Comcast Cable Communications, LLC
    Inventors: Douglas Bay, David Leach
  • Patent number: 11736730
    Abstract: Systems, methods, and apparatuses are described for processing video. Encoded video data may be determined from uncompressed video data. A chrominance component for a portion of the encoded video data may be determined that references another portion of the encoded video data. A luma component of the portion of the encoded video data may be determined to correspond with the luma component of the corresponding portion of the uncompressed video data.
    Type: Grant
    Filed: January 25, 2022
    Date of Patent: August 22, 2023
    Assignee: Comcast Cable Communications, LLC
    Inventors: Douglas Bay, David Leach