Patents by Inventor David Leach

David Leach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11251681
    Abstract: A method for securing metallic first and second parts together includes positioning filler metal along an interface between the first and second parts. The first and second parts are inserted into a fixture such that at least one of the first and second parts engages the fixture. The fixture is heated with at least one electrical heating element to heat the filler metal by thermal conduction above a melting point of the filler metal and form metallurgical bonds between the filler metal and the first and second parts. The melted filler metal is cooled to join the first and second parts together.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: February 15, 2022
    Assignee: KOCH ENGINEERED SOLUTIONS, LLC
    Inventors: Russel H. Marvin, Dylan Broomfield, David Leach
  • Patent number: 11203986
    Abstract: A method of operating a rotary machine below a minimum emissions compliance load in a response mode includes reducing a fuel split to zero. The fuel split apportions a total flow of fuel to the combustor between a first combustion zone and a second combustion zone. The method also includes determining a current operating temperature of the first combustion zone using a digital simulation of the rotary machine. The method further includes determining a target operating temperature of the first combustion zone. The target operating temperature enables the rotary machine to operate below a traditional Minimum Emissions Compliance Load (MECL) while still in compliance with emissions standards. The method also includes channeling a first flow of fuel to the first combustion zone. The first flow of fuel decreases the temperature of the first combustion zone to the target operating temperature.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: December 21, 2021
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: David Leach, Valerie Suzanne Vernet, Jason Nathaniel Cook, Jayaprakash Natarajan
  • Publication number: 20210386907
    Abstract: Provided herein are peptide-based hydrogels, or neutral multidomain peptide hydrogel (NMDP), as well as uses thereof. The uses include encapsulating cells to induce quiescence for long-term storage and administering to a subject to induce collagen deposition and macrophage infiltration. The disclosed hydrogel is useful for the preservation of stem cells, including maintaining their quiescence and differentiation potential.
    Type: Application
    Filed: October 16, 2019
    Publication date: December 16, 2021
    Applicant: William Marsh Rice University
    Inventors: Jeffrey HARTGERINK, David LEACH, Tania LOPEZ-SILVA
  • Patent number: 11202049
    Abstract: Methods and systems for managing content items are described. A content item may be separated into components, such as chroma components, luminance components, and audio components. For more efficient management of the content, including for storage and delivery of the content, the separate components may be stored at different locations. For example, chroma components may be stored on a central server, while luminance and audio components are stored at other locations, such as edge servers, or vice versa, to accommodate network efficiency considerations. When content is delivered to a player, two or more separate streams carrying different content components may be delivered to the player.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: December 14, 2021
    Assignee: COMCAST CABLE COMMUNICATIONS, LLC
    Inventors: Douglas Bay, David Leach
  • Publication number: 20210381432
    Abstract: A method of operating a rotary machine below a minimum emissions compliance load in a response mode includes reducing a fuel split to zero. The fuel split apportions a total flow of fuel to the combustor between a first combustion zone and a second combustion zone. The method also includes determining a current operating temperature of the first combustion zone using a digital simulation of the rotary machine. The method further includes determining a target operating temperature of the first combustion zone. The target operating temperature enables the rotary machine to operate below a traditional Minimum Emissions Compliance Load (MECL) while still in compliance with emissions standards. The method also includes channeling a first flow of fuel to the first combustion zone. The first flow of fuel decreases the temperature of the first combustion zone to the target operating temperature.
    Type: Application
    Filed: June 8, 2020
    Publication date: December 9, 2021
    Inventors: David Leach, Valerie Suzanne Vernet, Jason Nathaniel Cook, Jayaprakash Natarajan
  • Publication number: 20210205468
    Abstract: Provided herein are compositions comprising multi domain peptide (MDP) hydrogels where the peptides that constitute the hydrogel have at least one N6-(1-iminoethyl)-lysine side chain. Also provided are hydrogels that further comprise a STING agonist, an immune checkpoint inhibitor, and/or an anti-cancer therapy. Also provided are methods of using such compositions in the treatment of cancer.
    Type: Application
    Filed: December 18, 2020
    Publication date: July 8, 2021
    Applicants: William Marsh Rice University, Baylor College of Medicine, The Board of Regents of the University of Texas System
    Inventors: Jeffrey HARTGERINK, Andrew G. SIKORA, David LEACH, Jared M. NEWTON, Simon YOUNG
  • Publication number: 20210136608
    Abstract: Access devices may receive signals over a network and calculate a frequency spectrum of the received signals. An analyzer system may collect the frequency spectrum data from multiple access devices, and based on the collected data, detect, identify, and locate sources of anomalies in a communication network.
    Type: Application
    Filed: August 20, 2020
    Publication date: May 6, 2021
    Inventors: Lawrence Wolcott, Justin Riggert, David Leach, Thomas Emerson Bach, James Russell, Edward David Monnerat, Todd Szuter, Bryan Thomas
  • Publication number: 20210113637
    Abstract: The invention relates to immunomodulatory compositions comprising one or more extracts from medicinal fungi, and the use of such compositions in the treatment or prevention of conditions or diseases associated with immunological dysfunction, and/or to provide one or more health benefits to an animal subject. In certain embodiments, the invention relates to compositions comprising multiple extracts from a number of medicinal mushrooms, and the use of such compositions to provide one or more health benefits to a subject in need thereof.
    Type: Application
    Filed: April 4, 2019
    Publication date: April 22, 2021
    Inventors: Joe TIRALONGO, Brody MALLARD, David LEACH, Hans WOHLMUTH
  • Patent number: 10798597
    Abstract: Access devices may receive signals over a network and calculate a frequency spectrum of the received signals. An analyzer system may collect the frequency spectrum data from multiple access devices, and based on the collected data, detect, identify, and locate sources of anomalies in a communication network.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: October 6, 2020
    Assignee: Comcast Cable Communications, LLC
    Inventors: Lawrence Wolcott, Justin Riggert, David Leach, Thomas Emerson Bach, James Russell, Edward David Monnerat, Todd Szuter, Bryan Thomas
  • Publication number: 20200296346
    Abstract: Methods and systems for managing content items are described. A content item may be separated into components, such as chroma components, luminance components, and audio components. For more efficient management of the content, including for storage and delivery of the content, the separate components may be stored at different locations. For example, chroma components may be stored on a central server, while luminance and audio components are stored at other locations, such as edge servers, or vice versa, to accommodate network efficiency considerations. When content is delivered to a player, two or more separate streams carrying different content components may be delivered to the player.
    Type: Application
    Filed: March 15, 2019
    Publication date: September 17, 2020
    Inventors: Douglas Bay, David Leach
  • Publication number: 20200146975
    Abstract: In one aspect, the present disclosure provides for novel compositions of matter comprising multi domain peptide (MDP) hydrogels and cyclic dinucleotides (CDNs). Also disclosed are method of using such compositions in the treatment of cancer, including in particular the treatment of head and neck cancers, such as those resistant to CDN therapy.
    Type: Application
    Filed: June 15, 2018
    Publication date: May 14, 2020
    Applicants: WILLIAM MARSH RICE UNIVERSITY, THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Simon YOUNG, David LEACH, Jeffrey D. HARTGERINK
  • Publication number: 20200045338
    Abstract: Systems, methods, and apparatuses are described for processing video. Encoded video data may be determined from uncompressed video data. A chrominance component for a portion of the encoded video data may be determined that references another portion of the encoded video data. A luma component of the portion of the encoded video data may be determined to correspond with the luma component of the corresponding portion of the uncompressed video data.
    Type: Application
    Filed: August 1, 2018
    Publication date: February 6, 2020
    Inventors: Douglas Bay, David Leach
  • Publication number: 20200045570
    Abstract: Access devices may receive signals over a network and calculate a frequency spectrum of the received signals. An analyzer system may collect the frequency spectrum data from multiple access devices, and based on the collected data, detect, identify, and locate sources of anomalies in a communication network.
    Type: Application
    Filed: October 7, 2019
    Publication date: February 6, 2020
    Inventors: Lawrence Wolcott, Justin Riggert, David Leach, Thomas Emerson Bach, James Russell, Edward David Monnerat, Todd Szuter, Bryan Thomas
  • Patent number: 10477422
    Abstract: Access devices may receive signals over a network and calculate a frequency spectrum of the received signals. An analyzer system may collect the frequency spectrum data from multiple access devices, and based on the collected data, detect, identify, and locate sources of anomalies in a communication network.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: November 12, 2019
    Assignee: Comcast Cable Communications, LLC
    Inventors: Lawrence Wolcott, Justin Riggert, David Leach, Thomas Emerson Bach, James Russell, Edward David Monnerat, Todd Szuter, Bryan Thomas
  • Publication number: 20180270681
    Abstract: Access devices may receive signals over a network and calculate a frequency spectrum of the received signals. An analyzer system may collect the frequency spectrum data from multiple access devices, and based on the collected data, detect, identify, and locate sources of anomalies in a communication network.
    Type: Application
    Filed: October 23, 2017
    Publication date: September 20, 2018
    Inventors: Lawrence Wolcott, Justin Riggert, David Leach, Thomas Emerson Bach, James Russell, Edward David Monnerat, Todd Szuter, Bryan Thomas
  • Patent number: 9960984
    Abstract: A computing device performance monitor may be configured to collect performance metric information regarding one or more monitored computing devices, and may assign condition point values to each metric. The performance monitor may generate a total of the condition point values, and use the total to determine an appropriate response.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: May 1, 2018
    Assignee: Comcast Cable Communications, LLC
    Inventors: David Leach, James Russell, Timothy Parol, David Eng, Mark Anderson, Dante Burks
  • Publication number: 20170356342
    Abstract: A gas turbine fuel heating system is disclosed having at least one coalescing filter configured to accept a main fuel supply and a plurality of fuel circuit heaters. Each fuel circuit heater can be configured to accept an independent fuel circuit portion of the main fuel supply leaving the at least one coalescing filter and also configured to accept a heating medium circuit portion of a heating medium. The system can have a plurality of scrubbers, a plurality of fuel circuit manifolds, and a plurality of fuel premix tubes. A controller circuit determines the MWI for each independent fuel circuit portion and adjusts the heating medium circuit portion passed to the corresponding fuel circuit heater to maintain at least one parameter selected from the group consisting of a baseline independent fuel circuit portion MWI setpoint and a predetermined independent fuel circuit portion nozzle gas injector pressure ratio.
    Type: Application
    Filed: June 14, 2016
    Publication date: December 14, 2017
    Inventors: David Leach, Daniel R. Tegel, Alston Ilford Scipio, Praveen Kumar Uppaluri, Vishwanath R. Ardha, Sanji Ekanayake
  • Patent number: 9826424
    Abstract: Access devices may receive signals over a network and calculate a frequency spectrum of the received signals. An analyzer system may collect the frequency spectrum data from multiple access devices, and based on the collected data, detect, identify, and locate sources of anomalies in a communication network.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: November 21, 2017
    Assignee: Comcast Cable Communications, LLC
    Inventors: Lawrence Wolcott, Justin Riggert, David Leach, Thomas Emerson Bach, James Russell, Edward David Monnerat, Todd Szuter, Bryan Thomas
  • Patent number: 9771869
    Abstract: A fuel nozzle system for enabling a gas turbine to start and operate on low-Btu fuel includes a primary tip having primary fuel orifices and a primary fuel passage in fluid communication with the primary fuel orifices, and a fuel circuit capable of controlling flow rates of a first and second low-Btu fuel gases flowing into the fuel nozzle. The system is capable of operating at an ignition status, in which at least the first low-Btu fuel gas is fed to the primary fuel orifices and ignited to start the gas turbine, and a baseload status, in which at least the second low-Btu fuel gas is fired at baseload. The low-Btu fuel gas ignited at the ignition status has a content of the first low-Btu fuel gas higher than that of the low-Btu fuel gas fired at the baseload status. Methods for using the system are also provided.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: September 26, 2017
    Assignee: General Electric Company
    Inventors: Suhui Li, Joel Meier Haynes, Ping Yu, Wei Chen, David Leach, John Joseph Lipinski, Manuel Moises Cardenas, Jr., Wenjie Wu, Qingguo Zhang
  • Publication number: 20170194838
    Abstract: A method for securing metallic first and second parts together includes positioning filler metal along an interface between the first and second parts. The first and second parts are inserted into a fixture such that at least one of the first and second parts engages the fixture. The fixture is heated with at least one electrical heating element to heat the filler metal by thermal conduction above a melting point of the filler metal and form metallurgical bonds between the filler metal and the first and second parts. The melted filler metal is cooled to join the first and second parts together.
    Type: Application
    Filed: December 29, 2016
    Publication date: July 6, 2017
    Inventors: RUSSEL H. MARVIN, DYLAN BROOMFIELD, DAVID LEACH