Abstract: Pilot symbols and data symbols of a communication frame for an OTFS transmission system are two-dimensionally arranged along the points of a grid in the delay-Doppler domain. The pilot symbols are surrounded by guard symbols. The number of guard symbols in each direction of the Doppler domain is twice the number of the basis expansion modelling (BEM) basis functions used for modelling the communication channel in a receiver, and twice the maximum time delay in terms of delay bins in each direction of the delay domain. The receiver performs an initial pilot-aided channel estimation using BEM of a first BEM order and using the pilot signals, followed by an initial estimation of data symbols using the initial channel estimation, and iteratively performs data aided channel estimation using BEM of a second BEM order and at least the received data signals, until a termination criterion is met.

Abstract: A method includes determining, based on an image having an initial viewpoint, a depth image, and determining a foreground visibility map including visibility values that are inversely proportional to a depth gradient of the depth image. The method also includes determining, based on the depth image, a background disocclusion mask indicating a likelihood that pixel of the image will be disoccluded by a viewpoint adjustment. The method additionally includes generating, based on the image, the depth image, and the background disocclusion mask, an inpainted image and an inpainted depth image. The method further includes generating, based on the depth image and the inpainted depth image, respectively, a first three-dimensional (3D) representation of the image and a second 3D representation of the inpainted image, and generating a modified image having an adjusted viewpoint by combining the first and second 3D representation based on the foreground visibility map.

Abstract: Embodiments of the disclosure relate to articles, coated chamber components, and techniques of coating chamber components and systems. In particular, disclosed is a chamber component and methods of forming the chamber component that includes a substrate and a first layer disposed on the substrate, the first layer including a metal with a first atomic concentration. The chamber component further includes a second layer disposed on the first layer, the second layer including the metal with a second atomic concentration that is at least 5 percent higher than the first atomic concentration.

Abstract: The present invention is related to processes for preparing itacitinib, or a salt thereof, and related synthetic intermediates related thereto.

Abstract: Systems and methods for vehicle spatial path sampling are provided. The method includes obtaining an initial travel path for an autonomous vehicle from a first location to a second location and vehicle configuration data indicative of one or more physical constraints of the autonomous vehicle. The method includes determining one or more secondary travel paths for the autonomous vehicle from the first location to the second location based on the initial travel path and the vehicle configuration data. The method includes generating a spatial envelope based on the one or more secondary travel paths that indicates a plurality of lateral offsets from the initial travel path. And, the method includes generating a plurality of trajectories for the autonomous vehicle to travel from the first location to the second location such that each of the plurality of trajectories include one or more lateral offsets identified by the spatial envelope.

Abstract: The present disclosure provides autonomous vehicle systems and methods that include or otherwise leverage a motion planning system that generates constraints as part of determining a motion plan for an autonomous vehicle (AV). In particular, a scenario generator within a motion planning system can generate constraints based on where objects of interest are predicted to be relative to an autonomous vehicle. A constraint solver can identify navigation decisions for each of the constraints that provide a consistent solution across all constraints. The solution provided by the constraint solver can be in the form of a trajectory path determined relative to constraint areas for all objects of interest. The trajectory path represents a set of navigation decisions such that a navigation decision relative to one constraint doesn't sacrifice an ability to satisfy a different navigation decision relative to one or more other constraints.

Abstract: The present disclosure relates to a computer-implemented method for genetic placement of analog and mix-signal circuit components. Embodiments may include receiving an unplaced layout associated with an electronic circuit design and grouping requirements. Embodiments may also include identifying one or more instances that need to be placed in the unplaced layout and areas of the unplaced layout configured to receive the instances. Embodiments may further include analyzing one or more instances that need to be placed in the unplaced layout and the areas of the unplaced layout configured to receive the instances, wherein analyzing is based upon a row-based data structure. Embodiments may also include determining a location and an orientation for each of the one or more instances based upon the genetic algorithm and generating a placed layout based upon the determined location and orientation for each of the instances.

Abstract: The invention relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.

Abstract: Methods and systems for intrusion detection using federated learning. In some examples, a system includes a central server configured for generating an initial security model and distributing the initial security model to edge nodes. Each edge node is configured for executing an intrusion detection system. The system includes a first subset of edge nodes each of which is configured for training a respective local security model using captured security data during live operation. The system includes a second subset of edge nodes each of which is not configured for training a local security model. The system includes fog nodes, each fog node being on a communications path between at least one edge node and the central server. At least a first fog node is configured for training a respective local security model for one or more of the edge nodes from the second subset of edge nodes.

Abstract: The disclosed exemplary embodiments include computer-implemented systems, apparatuses, and processes that, among other things, generate and provision digital tokens based on dynamically obtained contextual data. For example, an apparatus may receive first information that characterizes an exchange of data initiated by a first application program executed by the apparatus, and may generate and transmit a signal to a computing system through a programmatic interface associated with a second application program executed by the apparatus. In some instances, the first signal may include the first information and data that instructs the computing system to obtain a digital token representative of a data type available for use in the data exchange. The apparatus may also receive a second signal that includes the digital token and based on the digital token, perform operations that present second information characterizing the available data type on an interface.

Abstract: A system and method for optimizing processing of keyboard/video/mouse (KVM) data in an internet protocol (IP) network environment receives via public interface access requests from users directed to KVM targets. The system includes a public and private virtual local area network (VLAN) linked by a bonded interface and general-purpose and optimized application containers. The general-purpose container initiates a KVM session and creates a network address translation (NAT) route (associated with an IP address visible to the user) and a dedicated interface via which the user may send KVM data directly and through the optimized application container, which prioritizes KVM data so it can pass without preemption through the private VLAN and to its intended KVM target in real-time or near real-time. The NAT route and external IP address may be reused for multiple access sessions to different KVM targets from the same user.

Abstract: An audio device with a body configured to be worn on or abutting an outer ear of a user, wherein the body is configured to contact at least one of the outer ear and the portion of the head that abuts the outer ear, at two separate spaced contact locations, and wherein the body is compliant at a body portion that defines one of the contact locations. The device also has an acoustic module carried by the body and configured to locate a sound-emitting opening anteriorly of and proximate the user's ear canal opening when the body is worn on or abutting the ear of the user.

Abstract: The present disclosure is directed to a deep learning system for differential diagnoses of skin diseases. In particular, the system performs a method that can include obtaining a plurality of images that respectively depict a portion of a patient's skin. The method can include determining, using a machine-learned skin condition classification model, a plurality of embeddings respectively for the plurality of images. The method can include combining the plurality of embeddings to obtain a unified representation associated with the portion of the patient's skin. The method can include determining, using the machine-learned skin condition classification model, a skin condition classification for the portion of the patients skin, the skin condition classification produced by the machine-learned skin condition classification model by processing the unified representation, wherein the skin condition classification identifies one or more skin conditions selected from a plurality of potential skin conditions.

Abstract: Systems, methods, and non-transitory computer-readable media can determine sensor data captured by at least one sensor of a vehicle while navigating an environment over a period of time. Information describing one or more agents associated with the environment during the period of time can be determined based at least in part on the captured sensor data. A parameter-based encoding describing the one or more agents associated with the environment during the period of time can be generated based at least in part on the determined information and a scenario schema, wherein the parameter-based encoding provides a structured representation of the information describing the one or more agents associated with the environment. A scenario represented by the parameter-based encoding can be determined based at least in part on a cluster of parameter-based encodings to which the parameter-based encoding is assigned.

Abstract: The invention relates to thioether monomer and dimer peptide molecules which inhibit binding of a4?7 to the mucosal addressing cell adhesion molecule (MAdCAM) in vivo.

Abstract: Peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel disease, are disclosed.

Abstract: An electronic device, method, and computer readable medium for an invertible wavelet layer for neural networks are provided. The electronic device includes a memory and at least one processor coupled to the memory. The at least one processor is configured to receive an input to a neural network, apply a wavelet transform to the input at a wavelet layer of the neural network, and generate a plurality of subbands of the input as a result of the wavelet transform.

Abstract: Peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel disease, are disclosed.

Abstract: Provided herein are mutant interleukin-10 polypeptides, and fusion polypeptides comprising the mutant interleukin-10 polypeptides and antigen binding molecules. The present disclosure provides methods of modulating immune cell function by contacting the immune cell with fusion polypeptides of the present disclosure. In addition, the disclosure also provides polynucleotides encoding the disclosed fusion molecules, and vectors and host cells comprising such polynucleotides. The present disclosure further provides methods for producing the fusion molecules, pharmaceutical compositions comprising the same, and uses thereof.

Abstract: The invention relates to thioether monomer and dimer peptide molecules which inhibit binding of ?4?7 to the mucosal addressing cell adhesion molecule (MAdCAM) in vivo.