Abstract: The present disclosure provides methods and compositions comprising IL-21 polypeptides, targeted cytokine construct that selectively activates target immune cells (e.g., CD8+ T cells) over other immune cell types. The cytokine of the present disclosure can further comprise mutations that alter its charge distribution to improve its half-life within the blood.

Abstract: The present invention discloses a multifunctional Petri dish with two sealing structures to ensure that the water in the medium will not evaporate during continuous culture, further affecting cultured living material growth and development. In addition to alcohol spray, the multifunctional Petri dish allows the application of acids, alkalis, alcohols, peroxides solution, or peroxides gas to immerse the multi-purpose Petri dish to remove bacteria or viruses. Various accessory devices can meet all requirements for a living culture of cells and tissues that the existing Petri dishes cannot provide. Using the dish cover operator and the dish container operator is essential to ensure that the researcher's hands will not directly touch the Petri dish in the sterile operating bench, thereby blocking all potential contamination of the medium and culture by foreign organisms.

Abstract: The present disclosure provides methods and compositions comprising IL-21 polypeptides, targeted cytokine construct that selectively activates target immune cells (e.g., CD8+ T cells) over other immune cell types. The cytokine of the present disclosure can further comprise mutations that alter its charge distribution to improve its half-life within the blood.

Abstract: The present disclosure provides methods and compositions comprising IL-21 polypeptides, targeted cytokine construct that selectively activates target immune cells (e.g., CD8+ T cells) over other immune cell types. The cytokine of the present disclosure can further comprise mutations that alter its charge distribution to improve its half-life within the blood.

Abstract: Various embodiments are described herein for a device and method for interacting with customers on e-commerce platforms. The various embodiments described herein generally relate to methods and apparatus for interacting with customers. In one embodiment, the system may be used in conjunction with e-commerce platforms, electronic document platforms, and any other electronic platforms. In other embodiments, the interaction with customers can be on electronic documents, portable document formats (PDFs), email and other forms of electronic platforms. On e-commerce platforms, customers can use electronic devices such as laptops, tablets, and mobile devices to browse products before deciding to make a purchase decision.

Abstract: The invention relates to thioether monomer and dimer peptide molecules which inhibit binding of a4?7 to the mucosal addressing cell adhesion molecule (MAdCAM) in vivo.

Abstract: Peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel disease, are disclosed.

Abstract: An electronic device, method, and computer readable medium for an invertible wavelet layer for neural networks are provided. The electronic device includes a memory and at least one processor coupled to the memory. The at least one processor is configured to receive an input to a neural network, apply a wavelet transform to the input at a wavelet layer of the neural network, and generate a plurality of subbands of the input as a result of the wavelet transform.

Abstract: Peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel disease, are disclosed.

Abstract: Provided herein are mutant interleukin-10 polypeptides, and fusion polypeptides comprising the mutant interleukin-10 polypeptides and antigen binding molecules. The present disclosure provides methods of modulating immune cell function by contacting the immune cell with fusion polypeptides of the present disclosure. In addition, the disclosure also provides polynucleotides encoding the disclosed fusion molecules, and vectors and host cells comprising such polynucleotides. The present disclosure further provides methods for producing the fusion molecules, pharmaceutical compositions comprising the same, and uses thereof.

Abstract: The invention relates to thioether monomer and dimer peptide molecules which inhibit binding of ?4?7 to the mucosal addressing cell adhesion molecule (MAdCAM) in vivo.

Abstract: A demand-based load balancing function may be provided by one or more drive controllers that takes advantage of the affinity laws to linearize the control of the variable of interest (e.g., flow, pressure, etc.). Each drive controller may be set up by the user simply inputting a few values into the drive controller. Based on the inputs, the drive controllers may interpolate control points using an assumed linear relationship between the variable to be controlled (e.g., pressure) and the current driven to the pump. Feedback data from the system may be used to continually update the drive controllers so as to potentially allow them to better balance power usage to each pump.

Abstract: The system and methodology of the present invention employs available data obtained in connection with previous transactions to create one or more databases comprising feature sets which are used in transaction decision making solutions. The available data from previous transactions which is used in creating feature sets may include all available production data or the data may be stratified across specific industries and/or across specific decision support customers to optimize the expected decision making results. A feature engine is provided which uses a combination of data, time and combinational aggregate functions to feature engineer one or more feature sets used for one or more purposes, such purposes to include identity verification, fraud assessment, document verification as well as other assessments related to selectively permit or not permit transactions to proceed.

Abstract: The present disclosure provides methods and compositions comprising IL-21 polypeptides, targeted cytokine construct that selectively activates target immune cells (e.g., CD8+ T cells) over other immune cell types. The cytokine of the present disclosure can further comprise mutations that alter its charge distribution to improve its half-life within the blood.

Abstract: The present disclosure provides methods and compositions comprising IL-21 polypeptides, targeted cytokine construct that selectively activates target immune cells (e.g., CD8+ T cells) over other immune cell types. The cytokine of the present disclosure can further comprise mutations that alter its charge distribution to improve its half-life within the blood.

Abstract: The present disclosure provides technical solutions related to intelligent cloud management based on profile. Artificial intelligent is applied to cloud management and cloud management suggestion may be proposed intelligently. In daily work, behaviors in using cloud resources may show characteristics of cloud users or cloud tenants themselves. The technical solution of intelligent cloud management of the present disclosure generates profile identifying cloud using characteristics by extracting behavior data in using cloud and intelligently proposes cloud management suggestions based on the profile.

Abstract: The present invention provides hepcidin analogues with improved in vivo half lives, and related pharmaceutical compositions and methods of use thereof.

Abstract: An electronic device includes a display, a camera, and a processing device. The processing device is configured to determine whether (i) a user's face or eyes are within the camera's field of view or (ii) a gaze of the user is directed towards the display. The processing device is also configured, in response to determining that (i) the user's face or eyes are not within the camera's field of view or (ii) the gaze of the user is not directed towards the display, to modify a user interface button presented on the display. The user interface button may represent a shutter button configured to cause the camera or another camera of the electronic device to capture one or more images.

Abstract: The present disclosure provides technical solutions related to intelligent cloud management based on profile. Artificial intelligent is applied to cloud management and cloud management suggestion may be proposed intelligently. In daily work, behaviors in using cloud resources may show characteristics of cloud users or cloud tenants themselves. The technical solution of intelligent cloud management of the present disclosure generates profile identifying cloud using characteristics by extracting behavior data in using cloud and intelligently proposes cloud management suggestions based on the profile.