Patents by Inventor David Liu

David Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL a4B7 PEPTIDE MONOMER AND DIMER ANTAGONISTS
    Publication number: 20200308229
    Abstract: The invention relates to peptide dimer compounds and peptide monomer compounds that potently inhibit binding of ?4?7 to the mucosal addressin cell adhesion molecule (MAdCAM) in vivo, possess high selectivity against ?4?1 binding, and have high stability under gastrointestinal conditions.
    Type: Application
    Filed: February 4, 2020
    Publication date: October 1, 2020
    Inventors: Ashok BHANDARI, Dinesh V. PATEL, Genet Zemede, Larry C. Mattheakis, David Liu
  • Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
    Patent number: 10787490
    Abstract: Peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel diseases, are described.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: September 29, 2020
    Assignee: Protaganist Therapeutics, Inc.
    Inventors: Ashok Bhandari, Gregory Bourne, Xiaoli Cheng, Brian Troy Frederick, Jie Zhang, Dinesh V. Patel, David Liu
  • CAPTURING A PHOTO USING A SIGNATURE MOTION OF A MOBILE DEVICE
    Publication number: 20200267331
    Abstract: A method of capturing a photo using a mobile device is described. The method comprises detecting a signature motion of the mobile device; capturing video using a camera of the mobile device upon detecting the signature motion; and automatically identifying a start frame and an end frame of the captured images using neural networks. A mobile device for capturing a photo is also described.
    Type: Application
    Filed: March 29, 2019
    Publication date: August 20, 2020
    Applicant: Samsung Electronics, Co. Ltd.
    Inventors: David Liu, Michael Polley, Youngjun F. Yoo, Hamid Rahim Sheikh, Kaimo Lin, George Chen, Chenchi Luo
  • SYSTEM AND METHOD FOR AI ENHANCED SHUTTER BUTTON USER INTERFACE
    Publication number: 20200267324
    Abstract: An electronic device, a method, and computer readable medium for operating an electronic device are disclosed. The method includes receiving data about a state of the electronic device from one or more sensors of the electronic device. The method also includes determining whether to modify a user interface button displayed on a display of the electronic device based on the received state data and parameters of a neural network. The method further includes modifying display of the user interface button on the display of the electronic device based on determining to modify. The method additionally includes providing, to the neural network, feedback data indicating whether the user interface button was triggered within a predetermined time period after modifying the user interface button.
    Type: Application
    Filed: February 19, 2019
    Publication date: August 20, 2020
    Inventors: David Liu, Youngjun Yoo
  • Tissue characterization based on machine learning in medical imaging
    Patent number: 10748277
    Abstract: Tissue is characterized using machine-learnt classification. The prognosis, diagnosis or evidence in the form of a similar case is found by machine-learnt classification from features extracted from frames of medical scan data. The texture features for tissue characterization may be learned using deep learning. Using the features, therapy response is predicted from magnetic resonance functional measures before and after treatment in one example. Using the machine-learnt classification, the number of measures after treatment may be reduced as compared to RECIST for predicting the outcome of the treatment, allowing earlier termination or alteration of the therapy.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: August 18, 2020
    Assignees: Siemens Healthcare GmbH, The Johns Hopkins University
    Inventors: Shaohua Kevin Zhou, David Liu, Berthold Kiefer, Atilla Peter Kiraly, Benjamin L. Odry, Robert Grimm, Li Pan, Ihab Kamel
  • Opioid agonist peptides and uses thereof
    Patent number: 10729676
    Abstract: The invention is directed to opioid agonist peptides and their use.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: August 4, 2020
    Assignee: Protagonist Theraputics, Inc.
    Inventors: Sampath Kumar Anandan, Jie Zhang, Ashok Bhandari, Gregory Thomas Bourne, Brian Troy Frederick, Larry C. Mattheakis, David Liu, Mukund M. Mehrotra
  • NOVEL a4B7 THIOETHER PEPTIDE DIMER ANTAGONISTS
    Publication number: 20200239523
    Abstract: The invention relates to thioether monomer and dimer peptide molecules which inhibit binding of ?4?7 to the mucosal addressing cell adhesion molecule (MAdCAM) in vivo.
    Type: Application
    Filed: January 28, 2020
    Publication date: July 30, 2020
    Inventors: Ashok Bhandari, Dinesh V. Patel, Genet Zemede, Brian Troy Frederick, Larry C. Mattheakis, David Liu
  • CAPILLARY ELECTROPHORESIS SYSTEMS, RELATED DEVICES, AND RELATED METHODS
    Publication number: 20200232943
    Abstract: A biological analysis device (100) for performing capillary electrophoresis includes a voltage section (124) configured to generate a voltage differential across a cathode (106) connector and an anode (116) connector, an optical detector system (112) configured to detect light emission from a sample, a temperature regulation section (126), and a cartridge holding portion configured to receive at least a portion of a removable cartridge (102) comprising one or more capillaries (104) and a separation medium container (118). The biological analysis device may include one or more actuators (122) configured to actuate components of the removable cartridge when the removable cartridge is received in the cartridge holding portion. Devices and methods relate to biological analysis.
    Type: Application
    Filed: February 23, 2018
    Publication date: July 23, 2020
    Inventors: Gary LIM, David LIU, Peng LI, Bin CAO, Kirk HIRANO, Alexander DUKHOVNY, John DIXON
  • ANTI SEZ6 ANTIBODIES AND METHODS OF USE
    Publication number: 20200181256
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
    Type: Application
    Filed: December 12, 2019
    Publication date: June 11, 2020
    Applicant: ABBVIE STEMCENTRX LLC
    Inventors: LAURA SAUNDERS, SCOTT J. DYLLA, ORIT FOORD, ROBERT A. STULL, MICHAEL TORGOV, HUI SHAO, DAVID LIU
  • Semiconductor Device With Dual Types of Zero Cost Embedded Memory
    Publication number: 20200168740
    Abstract: An integrated circuit includes two different types of embedded memories, with cells that have different retention characteristics, and situated in different areas of the substrate. In some applications the cells are both non-volatile memories sharing a common gate layer but with different oxide layers, different thicknesses, etc. The first type of cell is a conventional flash cell which can be part of a logic/memory region, while the second type of cell uses capacitive coupling and can be located in a high voltage region. Because of their common features, the need for additional masks, manufacturing steps, etc. can be mitigated.
    Type: Application
    Filed: January 29, 2020
    Publication date: May 28, 2020
    Applicant: JONKER, LLC
    Inventor: David Liu
  • DLL3 MODULATORS AND METHODS OF USE
    Publication number: 20200138969
    Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
    Type: Application
    Filed: December 6, 2019
    Publication date: May 7, 2020
    Applicant: ABBVIE STEMCENTRX LLC
    Inventors: Robert A. Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
  • Semiconductor CMOS non-volatile memory device
    Patent number: 10629607
    Abstract: A nonvolatile memory device may operate with a logic transistor, which includes a transistor gate formed of a material. The memory device includes a floating gate formed of the material, a first-type fin, and a second-type fin. The first-type fin includes a first-type channel, a first-type source, and a first-type drain. The first-type channel, the first-type source, and the first-type drain have a first conductivity type. The second-type fin includes a second-type channel, a second-type source, and a second-type drain. The second-type source and the second-type drain have the first conductivity type. The second-type channel has a second conductivity type opposite to the first conductivity type. The floating gate is positioned on the first-type channel and the second-type channel.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: April 21, 2020
    Inventors: David Liu, Ben Sheen
  • ?4?7 thioether peptide dimer antagonists
    Patent number: 10626146
    Abstract: The invention relates to thioether monomer and dimer peptide molecules which inhibit binding of ?4?7 to the mucosal addressing cell adhesion molecule (MAdCAM) in vivo.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: April 21, 2020
    Assignee: Protagonist Therapeutics, Inc.
    Inventors: Ashok Bhandari, Dinesh V. Patel, Genet Zemede, Brian Troy Frederick, Larry C. Mattheakis, David Liu
  • Semiconductor CMOS Non-Volatile Memory Device
    Publication number: 20200119023
    Abstract: A nonvolatile memory device may operate with a logic transistor, which includes a transistor gate formed of a material. The memory device includes a floating gate formed of the material, a first-type fin, and a second-type fin. The first-type fin includes a first-type channel, a first-type source, and a first-type drain. The first-type channel, the first-type source, and the first-type drain have a first conductivity type. The second-type fin includes a second-type channel, a second-type source, and a second-type drain. The second-type source and the second-type drain have the first conductivity type. The second-type channel has a second conductivity type opposite to the first conductivity type. The floating gate is positioned on the first-type channel and the second-type channel.
    Type: Application
    Filed: October 11, 2018
    Publication date: April 16, 2020
    Inventors: David Liu, Ben Sheen
  • Liver disease assessment in medical imaging
    Patent number: 10610302
    Abstract: For liver modeling from medical scan data, multiple modalities of imaging are used. By using multiple modalities of imaging in combination with generative modeling, a more comprehensive and informed assessment may be performed. The generative modeling may allow feedback of effects of proposed therapy on function of the liver. This feedback is used to update the liver function information based on the imaging. Based on the computerized modeling with information from various imaging modes, an output based on more comprehensive information and patient personalized modeling and feedback may be provided to assist the physician.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: April 7, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Dorin Comaniciu, Thomas Pheiffer, David Liu, Ankur Kapoor, Tommaso Mansi
  • Atlas-based contouring of organs at risk for radiation therapy
    Patent number: 10607342
    Abstract: Embodiments can provide a method for atlas-based contouring, comprising constructing a relevant atlas database; selecting one or more optimal atlases from the relevant atlas database; propagating one or more atlases; fusing the one or more atlases; and assessing the quality of one or more propagated contours.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: March 31, 2020
    Assignee: Siemenes Healthcare GmbH
    Inventors: Li Zhang, Shanhui Sun, Shaohua Kevin Zhou, Daguang Xu, Zhoubing Xu, Tommaso Mansi, Ying Chi, Yefeng Zheng, Pavlo Dyban, Nora Hünemohr, Julian Krebs, David Liu
  • Efficient delivery of therapeutic molecules in vitro and in vivo
    Patent number: 10583201
    Abstract: A chimeric molecule of one or more proteins or peptides fused, complexed or linked to one or more anionic molecules. Efficient in vitro and in vivo delivery is attained by encapsulating these molecules in cationic lipids or cationic liposomes. Methods of treatment include the intracellular delivery of these molecules to a specific therapeutic target.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: March 10, 2020
    Assignee: Massachusetts Eye and Ear Infirmary
    Inventors: Zheng-Yi Chen, David Liu
  • Deep learning based bone removal in computed tomography angiography
    Patent number: 10582907
    Abstract: A method and apparatus for deep learning based automatic bone removal in medical images, such as computed tomography angiography (CTA) volumes, is disclosed. Bone structures are segmented in a 3D medical image of a patient by classifying voxels of the 3D medical image as bone or non-bone voxels using a deep neural network trained for bone segmentation. A 3D visualization of non-bone structures in the 3D medical image is generated by removing voxels classified as bone voxels from a 3D visualization of the 3D medical image.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: March 10, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Mingqing Chen, Tae Soo Kim, Jan Kretschmer, Sebastian Seifert, Shaohua Kevin Zhou, Max Schöbinger, David Liu, Zhoubing Xu, Sasa Grbic, He Zhang
  • Zero cost NVM cell using high voltage devices in analog process
    Patent number: 10559700
    Abstract: A non-volatile memory cell and array structure is disclosed situated within a high voltage region of an integrated circuit. The cell utilizes capacitive coupling based on an overlap between a gate and a drift region to impart a programming voltage. Programming is effectuated using a drain extension which can act to inject hot electrons. The cell can be operated as a one-time programmable (OTP) or multiple-time programmable (MTP) device. The fabrication of the cell relies on processing steps associated with high voltage devices, thus avoiding the need for additional masks, manufacturing steps, etc.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: February 11, 2020
    Assignee: JONKER LLC
    Inventor: David Liu
  • Anti SEZ6 antibodies and methods of use
    Patent number: 10533051
    Abstract: Provided are novel seizure related 6 (SEZ6) modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: January 14, 2020
    Assignee: ABBVIE STEMCENTRX LLC
    Inventors: Laura Saunders, Scott J. Dylla, Orit Foord, Robert A. Stull, Michael Torgov, Hui Shao, David Liu