Patents by Inventor David M. Lynn

David M. Lynn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200204701
    Abstract: A printed document client receives a first print stream for a soft copy document, determines whether one or more conditions for adding a graphical symbol to the printed document are satisfied, and when the one or more conditions for adding the graphical symbol to the printed document are satisfied, adds the graphical symbol to the first print stream to generate a second print stream that includes the graphical symbol, and outputs the second print stream to a printer so the graphical symbol is printed on the printed document corresponding to the soft copy document. The printed document can be a hard copy document or a soft copy document generated from the second print stream.
    Type: Application
    Filed: March 2, 2020
    Publication date: June 25, 2020
    Inventors: Steven W. Irons, David R. Guilbault, Eric R. Lynn, Dale Shoup, Anthony Argenziano, Simon Okunev, Ian M. Miller
  • Publication number: 20200181419
    Abstract: The present invention provides methods of making polymer-based multilayer thin films, and polymer-based multilayer thin films made thereof, using controlled hydrolysis of functional side groups, such as azlactone groups, to obtain desired levels of roughness, porosity, and chemical reactivity.
    Type: Application
    Filed: December 5, 2018
    Publication date: June 11, 2020
    Inventors: Matthew CARTER, David M. LYNN
  • Patent number: 10623601
    Abstract: A printed document manager manages printed documents and is separate from Document Management Systems (DMSs) that manage electronic soft copy documents. One or more DMSs are registered with a postmark server. A client computing device executes a postmark client, detects a print event for a specified document, and queries a postmark server to determine whether the print event for the specified document should include a graphical postmark. In response, the postmark server queries one or more of the registered DMSs to determine whether the specified document matches a document in any of the repositories of the registered DMS(s). When the specified document to be printed matches a document in a registered DMS, the postmark server authorizes the postmark client to add the graphical postmark in a print stream corresponding to the print event for the specified document.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: April 14, 2020
    Assignee: DocSolid LLC
    Inventors: Steven W. Irons, David R. Guilbault, Eric R. Lynn, Dale Shoup, Anthony Argenziano, Simon Okunev, Ian M. Miller
  • Patent number: 10621239
    Abstract: A printed document manager manages printed documents and is separate from Document Management Systems (DMSs) that manage electronic soft copy documents. One or more DMSs are registered with a postmark server. A client computing device executes a postmark client, detects a print event for a specified document, and queries a postmark server to determine whether the print event for the specified document should include a graphical postmark. In response, the postmark server queries one or more of the registered DMSs to determine whether the specified document matches a document in any of the repositories of the registered DMS(s). When the specified document to be printed matches a document in a registered DMS, the postmark server authorizes the postmark client to add the graphical postmark in a print stream corresponding to the print event for the specified document.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: April 14, 2020
    Assignee: DocSolid LLC
    Inventors: Steven W. Irons, David R. Guilbault, Eric R. Lynn, Dale Shoup, Anthony Argenziano, Simon Okunev, Ian M. Miller
  • Patent number: 10557042
    Abstract: The present invention provides polymer-based slippery liquid-infused porous surfaces (SLIPS) that can prevent adhesion and colonization by fungal and bacterial pathogens and also kill and/or attenuate the colonization and virulence of non-adherent pathogens in surrounding media. The present approach exploits the polymer and liquid oil phases in these slippery materials to sustain the release of small molecules such as a broad-spectrum antimicrobial agent, an antifungal agent, an antibacterial agent, an agent that modulates bacterial or fungal quorum sensing, an agent that attenuates virulence, or a combination thereof. This controlled release approach improves the inherent anti-fouling properties of SLIPS, has the potential to be general in scope, and expands the potential utility of slippery, non-fouling surfaces in both fundamental and applied contexts.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: February 11, 2020
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: David M. Lynn, Uttam Manna
  • Patent number: 10329364
    Abstract: Polymerization catalyst compositions are provided as are methods of their preparation. The compositions comprise fatty amines and find advantageous use in olefin polymerization processes. The catalyst composition comprises at least one supported polymerization catalyst wherein the catalyst composition is modified with at least one fatty amine wherein the fatty amine is substantially free of particulate inorganic material.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: June 25, 2019
    Assignee: Univation Technologies, LLC
    Inventors: Richard B. Pannell, David M. Glowczwski, Chi-I Kuo, Timothy R. Lynn, Fathi David Hussein, Phuong A. Cao, Wesley R. Mariott, Michael D. Awe
  • Patent number: 10292390
    Abstract: Compounds described herein inhibit biofilm formation or disperse pre-formed biofilms of Gram-negative bacteria. Biofilm-inhibitory compounds can be encapsulated or contained in a polymer matrix for controlled release. Coatings, films, multilayer films, hydrogels, microspheres and nanospheres as well as pharmaceutical compositions and disinfecting compositions containing biofilm-inhibitory compounds are also provided. Methods for inhibiting formation of biofilms or dispersing already formed biofilms are provided. Methods for treating infections of gram-negative bacteria which form biofilms, particularly those of Pseudomonas and more particularly P. aeruginosa.
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: May 21, 2019
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Helen Blackwell, Reto Frei, Anthony Breitbach, David M. Lynn, Adam H. Broderick
  • Publication number: 20190060860
    Abstract: Described is a method of synthesizing nucleic acids on polyester substrates and the resulting compositions of matter. The method synthesizes nucleic acids from surface hydroxyl initiation points present on the substrate surface. These surface hydroxyls are present either naturally, or as a result of a chemical treatment to cleave ester bonds on the substrate surface. The preferred polyester substrate contains PET.
    Type: Application
    Filed: August 28, 2018
    Publication date: February 28, 2019
    Inventors: Matthew T. Holden, Matthew C.D. Carter, Lloyd M. Smith, David M. Lynn
  • Publication number: 20180230318
    Abstract: The present invention provides polymer-based slippery liquid-infused porous surfaces (SLIPS) that can prevent adhesion and colonization by fungal and bacterial pathogens and also kill and/or attenuate the colonization and virulence of non-adherent pathogens in surrounding media. The present approach exploits the polymer and liquid oil phases in these slippery materials to sustain the release of small molecules such as a broad-spectrum antimicrobial agent, an antifungal agent, an antibacterial agent, an agent that modulates bacterial or fungal quorum sensing, an agent that attenuates virulence, or a combination thereof. This controlled release approach improves the inherent anti-fouling properties of SLIPS, has the potential to be general in scope, and expands the potential utility of slippery, non-fouling surfaces in both fundamental and applied contexts.
    Type: Application
    Filed: March 28, 2017
    Publication date: August 16, 2018
    Inventors: David M. LYNN, Uttam MANNA
  • Patent number: 9700627
    Abstract: Poly(?-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the poly(amine) nature of these polymers, they are particularly suited for the delivery of polynucleotides. Nanoparticles containing polymer/polynucleotide complexes have been prepared. The inventive polymers may also be used to encapsulate other agents to be delivered. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: July 11, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Robert S. Langer, David M. Lynn, David A. Putnam, Mansoor M. Amiji, Daniel Griffith Anderson
  • Patent number: 9592300
    Abstract: The present invention provides methods utilizing redox-active surfactants to provide electrochemical control over polymer interactions. In one embodiment, the invention is directed to a transfection method using a redox-active transfection agent that preferentially promotes transfection dependent on the oxidation state of the transfection agent. Accordingly, certain methods according to the invention provide spatial and/or temporal control of cell transfection.
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: March 14, 2017
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Nicholas L. Abbott, David M. Lynn, Yukishige Kondo, Christopher M. Jewell, Melissa E. Hays
  • Patent number: 9400244
    Abstract: Devices and methods for immobilizing micrometer sized liquid domains onto a chemically functionalized substrate surface are disclosed. A multifunctional polymer is adsorbed at the surface interface of the liquid microdomains, and the liquid microdomains are immobilized by covalent bonding or non-covalent forces such as electrostatic attraction between the adsorbed multifunctional polymer and the functionalized substrate surface.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: July 26, 2016
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: David M. Lynn, Nicholas L. Abbott, Maren E. Buck, Michael I. Kinsinger
  • Patent number: 9370534
    Abstract: Pharmaceutical compositions containing biocidal co-polymers of poly(styrenes), poly(acrylates), poly(acrylamides), and poly(C1-C6)alkylene glycols are disclosed, along with methods of using the compositions to treat microbial infections in mammals.
    Type: Grant
    Filed: April 15, 2015
    Date of Patent: June 21, 2016
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Samuel H. Gellman, Michael A. Gelman, Bernard Weisblum, David M. Lynn
  • Publication number: 20160022821
    Abstract: Poly(?-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the poly(amine) nature of these polymers, they are particularly suited for the delivery of polynucleotides. Nanoparticles containing polymer/polynucleotide complexes have been prepared. The inventive polymers may also be used to encapsulate other agents to be delivered. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.
    Type: Application
    Filed: July 28, 2015
    Publication date: January 28, 2016
    Applicant: Massachusetts Institute of Technology
    Inventors: Robert S. Langer, David M. Lynn, David A. Putnam, Mansoor M. Amiji, Daniel Griffith Anderson
  • Publication number: 20150224135
    Abstract: Pharmaceutical compositions containing biocidal co-polymers of poly(styrenes), poly(acrylates), poly(acrylamides), and poly(C1-C6)alkylene glycols are disclosed, along with methods of using the compositions to treat microbial infections in mammals.
    Type: Application
    Filed: April 15, 2015
    Publication date: August 13, 2015
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Samuel H. Gellman, Michael A. Gelman, Bernard Weisblum, David M. Lynn
  • Patent number: 9101666
    Abstract: Poly(?-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the poly(amine) nature of these polymers, they are particularly suited for the delivery of polynucleotides. Nanoparticles containing polymer/polynucleotide complexes have been prepared. The inventive polymers may also be used to encapsulate other agents to be delivered. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: August 11, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Robert S. Langer, David M. Lynn, David A. Putnam, Mansoor M. Amiji, Daniel Griffith Anderson
  • Patent number: 9034309
    Abstract: Pharmaceutical compositions containing biocidal co-polymers of poly(styrenes), poly(acrylates), poly(acrylamides), and poly(C1-C6)alkylene glycols are disclosed, along with methods of using the compositions to treat microbial infections in mammals.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: May 19, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Samuel H. Gellman, Michael A. Gelman, Bernard Weisblum, David M. Lynn
  • Patent number: 8962001
    Abstract: A class of anionic oligomers and polymers that function for inhibition of nucleases, particularly RNase. Specific inhibitors include mixtures of oligomers of vinyl sulfate. Methods for inhibition or inactivation of one or more nucleases in vitro which comprises the step of contacting the one or more nucleases in a biological medium with one or more of the anionic oligomeric or polymeric inhibitors of this invention. Kits for carrying out a biological procedure, biological reaction and/or a biological assay containing one or more inhibitors of this invention. The use of oligomers and/or polymers of this invention as additives in buffers or reagents. The inhibitors of the invention can also be attached to surfaces to provide for removal of nucleases from media, solutions or other liquids in contact with the solid.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: February 24, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Ronald T. Raines, Bryan D. Smith, Matthew B. Soellner, David M. Lynn
  • Patent number: 8834918
    Abstract: A composition for delivery of a molecule into a cell is provided. The composition includes a protein transduction domain that is conjugated to the molecule which is incorporated into a multilayered film. Preferably, the protein transduction domain is a cationic protein transduction domain. More preferably, the cationic protein transduction domain is nonaarginine, and the multilayered film includes polyelectrolyte multilayers. When the composition is presented to a cell, the multilayered film dissolves or erodes in physiological media, and the molecule is delivered into the cell.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: September 16, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: David M. Lynn, Ronald T. Raines, Christopher M. Jewell, Stephen M. Fuchs, Ryan M. Flessner
  • Patent number: 8734851
    Abstract: The present invention provides implantable medical devices coated with polyelectrolyte assemblies that are fabricated by layer-by-layer deposition of nucleic acid and polycation. Such devices facilitate the local delivery of a nucleic acid contained in the polyelectrolyte assembly into a cell or tissue at an implantation site. Also provided are methods of fabricating and using implantable medical devices according to the invention.
    Type: Grant
    Filed: May 1, 2006
    Date of Patent: May 27, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: David M. Lynn, Jingtao Zhang, Christopher M. Jewell, Nathaniel J. Fredin