Abstract: A drink cup includes a body formed to include an interior region providing a fluid-holding reservoir and a brim. The brim is coupled to the body to form an opening into the interior region. The body includes a floor and a sidewall that extends away from the floor. The drink cup further includes a body-strengthening system coupled to the body.

Abstract: A wearable exoskeleton and methods of use are discussed herein. The exoskeleton comprises two shoulder bridges connecting a front harness and a back structural plate over shoulders of a user's body, and a back elastomeric element, connected to a tension cable system with shoulder clutches in which the tension cable can be reeled in or out, positioned to follow the back functional line of a user's body with a pre-tension cable system which all together form an artificial myofascial tension line in the exoskeleton. Other elastomeric elements may follow other user's body's myofascial lines to form the other artificial myofascial tension lines and to assist the user in handling objects.

Abstract: A patient bed has a siderail that is movable to a raised position elevated over a central region of a mattress of the patient bed for use as part of a patient lift of the patient bed. In a lowered position, the siderail blocks egress of a patient from the mattress. In the raised position of the siderail, a sling arm is coupleable to the siderail and a sling is coupleable to hooks of the sling arm.

Abstract: A formulation includes a base resin, a nucleating agent, and a blowing agent. The formulation can be used to form a container.

Abstract: A drink cup includes a body formed to include an interior region providing a fluid-holding reservoir and a brim. The brim is coupled to the body to form an opening into the interior region. The body includes a floor and a sidewall that extends away from the floor. The drink cup further includes a body-strengthening system coupled to the body.

Abstract: A transport system for a medical facility includes a support apparatus including a frame assembly. The frame assembly includes a frame connector. A care cart assembly includes a cart connector selectively coupled with the frame connector. The care cart assembly includes a body defining receiving spaces that are configured to receive care modules. Wheels are coupled to the body and configured to engage an underlying floor surface. A power drive system includes a power drive wheel operable between a retracted position spaced from the underlying floor surface and a deployed position engaging the underlying floor surface. The care cart assembly is configured to drive movement of the support apparatus with the power drive system when coupled with the support apparatus and when the power drive wheel is engaging the underlying floor surface.

Abstract: A hybrid edge and cloud system for detecting and identifying bird vocalizations including an edge device having an edge neural network. The edge neural network is trained with audio samples for making predictions about identification of the bird vocalizations. The system includes an audio sensor connected to the edge neural network for sending sound information to the edge neural network. The system includes a cloud computing system having a cloud neural network for processing the sound information, a first storage service, a second storage service, and a hit table which stores metadata about sound detections. The edge neural network generates a score for each of the trained audio samples based on predictions made from a sound audio clip and selects a top scoring audio sample. The hybrid edge and cloud system includes a browsing device having access to the cloud computing system and may request information from the hit table.

Abstract: The present invention relates to a group of resorcinol derivatives as a pharmaceutically active compounds and methods of preparation thereof. Resorcinol derivatives have been used to treat various diseases and disorders. While such treatments hold promise, there remains a need in the art for more effective treatments and this has been brought about by way of the resorcinol derivative of the invention.

Abstract: A load control system may include control devices for controlling power provided to an electrical load. The control devices may include an input device and a load control device. The load control system may include a hub device. The hub device may include a communication circuit and a control circuit. The communication circuit may be configured to receive a digital message from the control device. The control circuit may be configured to determine, based on content of the digital message, whether the control device has experienced a power removal event. The hub device may send, via the communication circuit, a power removal event indication to the control device of whether the control device has experienced the power removal event.

Abstract: A vacuum exhaust system includes a plurality of turbo pumps that evacuate a plurality of vacuum chambers. A plurality of chamber valves are positioned between the turbo pumps and the plurality of vacuum chambers. A plurality of branch channels are each connected to a corresponding exhaust of the plurality of turbo pumps and a main channel is formed from a confluence of the branch channels. A booster vacuum pump is connected to the main channel. A backing vacuum pump is connected to an exhaust of the booster vacuum pump. A plurality of bypass channels, each having a valve, provide a fluid communication path between at least some of the plurality of vacuum chambers and the booster vacuum pump.

Abstract: Compositions and methods useful for delivery of targeted therapies for pulmonary arterial hypertension, sepsis, cancer and cachexia. The compositions and methods are based on peptide pharmacophores that selectively bind to and home to diseased tissue and enable targeted therapies to affect a beneficial therapeutic result. Peptide pharmacophores may selectively target tumor vasculature, regenerating tissue, wounded tissue, inflamed tissue, fibrotic tissue, remodeled tissue, tissue characterized by elevated heparanase levels, and have the ability to internalize into such diseased cells.

Abstract: Compositions and methods useful for delivery of targeted therapies for pulmonary arterial hypertension, sepsis, cancer and cachexia. The compositions and methods are based on peptide pharmacophores that selectively bind to and home to diseased tissue and enable targeted therapies to affect a beneficial therapeutic result. Peptide pharmacophores may selectively target tumor vasculature, regenerating tissue, wounded tissue, inflamed tissue, fibrotic tissue, remodeled tissue, tissue characterized by elevated heparanase levels, and have the ability to internalize into such diseased cells.

Abstract: A conjugate for treating an individual suffering from a disease, wherein the conjugate is comprised of: a targeting peptide comprising a sequence substantially identical to CAR, or a variant thereof; and at least one therapeutic molecule and methods for making and administering same. Also disclosed is a combination product for use in the treatment of a disease, wherein the combination product comprises: (a) a targeting peptide comprising a sequence substantially identical to CAR, or a variant thereof; (b) a liposome, wherein the targeting peptide is encapsulated within the liposome; and (c) an effective amount of an anti-inflammatory agent and methods for making and administering same.

Abstract: Disclosed are compositions and methods useful for oral delivery of targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to affect a beneficial therapeutic result. The disclosed targeting is useful for oral delivery of therapeutic and detectable agents to diseased tissue in an animal.

Abstract: A lifting device (1, 14, 18, 28, 31, 36, 46, 50) has three booms (2, 19) of adjustable length, which in each case have a first end section (4, 20) and a second end section (5, 21) opposite the first end section (4, 20). While the first end sections (4, 20) of all booms (2, 19) are articulatedly connected to one another, the second end sections (5, 21) are articulatedly and rotatably mounted in respective bearings (7, 24, 29). The bearings (7, 24, 29) are thereby arranged at fixed positions relative to one another. Furthermore, in each boom (2, 19) at least the first end section (4, 20) can be rotated about the longitudinal axis of the boom (2, 19) with respect to the second end section (5, 21). In particular, the booms (2, 19) always form a tripod, which is characterized by a high stability. The lifting device (1, 14, 18, 28, 31, 36, 46, 50) is therefore suitable for lifting very heavy loads, wherein greater ranges can be achieved compared to known lifting devices.

Abstract: A vacuum exhaust system includes a plurality of low pressure vacuum pumps that operate in a molecular flow region and evacuate a plurality of vacuum chambers. A plurality of chamber valves are positioned between the low pressure vacuum pumps and the plurality of vacuum chambers. A plurality of branch channels are each connected to a corresponding exhaust of the plurality of low pressure vacuum pumps and a main channel is formed from a confluence of the branch channels. An intermediate vacuum pump is connected to the main channel and operates in a viscous flow region. A higher pressure vacuum pump operates in a higher pressure viscous flow region and is connected to an exhaust of the intermediate pressure vacuum pump. A plurality of bypass channels, each having a valve, provide a fluid communication path between at least some of the plurality of vacuum chambers and a higher pressure vacuum pump.

Abstract: An attenuator for high pressure fluid systems includes a shielding stud including first and second ends and a cylindrical space extending therebetween. The attenuator comprises a cylindrical, attenuator body disposed within the cylindrical space and defining a pressure chamber therein. First and second seal heads are positioned within first and second ends of said shielding stud and coupled to the attenuator body using a tensioner assembly and a plug threadingly coupled to first and second inner threaded surfaces of the shielding stud in first and second ends thereof.

Abstract: Disclosed are compositions and methods for triggering disease selective macropinocytosis. The compositions can serve as a marker of disease activity and as a trigger of enhanced macropinocytosis in tissues undergoing disease remodeling such as wound healing, cancer, PAH, inflammation, diabetes, Crohn's disease, ulcerative colitis, ankylosing spondylitis, diseases of the endometrium, psoriasis, irritable bowel syndrome, arthritis, fibrotic disorders, interstitial cystitis, autoimmune diseases, asthma, acute lung injury, and adult respiratory distress syndrome. The compositions can also serve as a receptor for disease selective cell penetrating peptides in the cells and extracellular matrix of diseased tissues.

Abstract: Disclosed are compositions and methods useful for oral delivery of targeted therapies for pulmonary diseases, fibrotic disorders and cancer. The compositions and methods are based on peptide sequences that selectively bind to and home to diseased tissue and enable targeted therapies to affect a beneficial therapeutic result. The disclosed targeting is useful for oral delivery of therapeutic and detectable agents to diseased tissue in an animal.