Abstract: A curing device includes a curing platform having at least one curing component arranged on a surface of the curing platform facing a print direction and at least one actuator connecting the curing platform to a dispensing tip. A three dimensional printing system includes a reservoir of curable material, a dispensing tip connected to the reservoir, a curing platform surrounding the dispensing tip, the curing platform having at least one curing component arranged on a surface of the curing platform facing a print direction, and at least one actuator connecting the curing platform to the dispensing tip.

Abstract: Retention devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and at least one reservoir contained within the housing. The at least one reservoir may have an actuation end and a release end and contain at least one drug formulation. A plug may be contained within the at least one reservoir and be moveable from the actuation end toward the release end. The device may also include an actuation system operably connected to the actuation end of the at least one reservoir and configured to drive the at least one drug formulation from the reservoir. The device may also include at least one retention member affixed to the housing and movable between a non-stressed position, a deployment position, and a retention position for retaining the device in an intraluminal location in the subject.

Abstract: A method of manufacturing a hierarchical laminate including forming a first hierarchical film, coating the first hierarchical film with an adhesive, stacking a second hierarchical film on the first hierarchical film, and curing the adhesive. A laminate structure has at least two electrohydrodynamic patterned film layers, the at least two layers being aligned and bonded.

Abstract: A system to fabricate hierarchical graded materials includes a reservoir to contain a material to be deposited, a print head connected to the reservoir to allow the print head to receive the material to be deposited, the print head having a mixing section, and an actuator connected to the print head, the actuator configured to actuate the print head in six axes of motion.

Abstract: An additive deposition system and method, the system including generating an aerosol of additive material that is charged and deposited onto a selectively charged substrate. Selectively charging the substrate includes uniformly charging a surface of the substrate, selectively removing charged from the substrate to create charged and neutral regions of the substrate surface. The charged regions of the substrate having a polarity opposite a polarity of the charged aerosol. The charged aerosol of additive material deposited onto the selectively charged portions of the substrate surface due to the potential difference between the charged substrate and charged aerosol. The system and method further including repeating the additive deposition process to create a multi-layer matrix of additive material.

Abstract: An additive deposition system and method, the system including generating an aerosol of additive material that is charged and deposited onto a selectively charged substrate. Selectively charging the substrate includes uniformly charging a surface of the substrate, selectively removing charged from the substrate to create charged and neutral regions of the substrate surface. The charged regions of the substrate having a polarity opposite a polarity of the charged aerosol. The charged aerosol of additive material deposited onto the selectively charged portions of the substrate surface due to the potential difference between the charged substrate and charged aerosol. The system and method further including repeating the additive deposition process to create a multi-layer matrix of additive material.

Abstract: A system and method for coating a substrate, the system including integrated powder coating material preparation and deposition of powder coating material onto a substrate. The system includes a feed input that processes the powder coating materials for use in a filament extension atomizer. The filament extension atomizer stretches fluid filaments of the powder coating material to form droplets of powder coating material. The droplets of powder coating material are partially cooled to prevent agglomeration and to form a powder coating material suitable for electrostatic deposition. The cooled powder coating material is electrostatically charged and directed onto the substrate surface, where it is deposited due to the electrostatic potential between the substrate and cooled droplets. The deposited powder coating material is then cured to the substrate to form a cohesive film of coating material across the substrate.

Abstract: Aerosols can be created by filament stretching and breaking of Newtonian and non-Newtonian fluids by applying a strain to and stretching the fluid. The fluid is stretched along a strain pathway and forms a fluid filament between diverging surfaces. The stretched fluid filament breaks into droplets that can be harvested to form a mist or aerosol. The aerosol creation systems can include one or more pairs of counter-rotating rollers that are positioned adjacent to each other that stretch the fluid or a pair of pistons that move toward and away from each other to stretch the fluid. Some aerosol creation systems can include multiple pairs of counter-rotating rollers that are positioned in a circular, oval, or linear pattern. The aerosol creation system with multiple pairs of counter-rotating rollers can generate mist is one or more directions and can be positioned between two concentric rings or linearly, among other configurations.

Abstract: An atomization device includes a pair of counter-rotating rollers, a fluid source configured to coat at least one of the rollers in a feed fluid, and a baffle unit. The counter-rotation of the rollers stretches the feed fluid into a fluid filament between the two diverging surfaces of the rollers. The stretched fluid filaments break into a plurality of droplets at a capillary break-up point of the feed fluid. The baffle unit introduces a baffle fluid within the interior of the device and the baffle fluid transports formed droplets of the feed fluid from the atomization device. Excess or misguided atomized fluid droplets are collected by the baffle unit and are recycled back into the device for use in later atomization processes. The variation of atomization device parameters allows for the selection of droplets having desired physical parameters.

Abstract: A liquid thin film is disposed on a conveyor surface (e.g., a roller or belt) that moves the thin film into a precisely controlled gap (or nip) region in which the liquid thin film is subjected to an electric field that causes the liquid to undergo electrohydrodynamic (EHD) patterning deformation, whereby portions of the liquid thin film form patterned liquid features having a micro-scale patterned shape. A curing mechanism (e.g., a UV laser) is used to solidify (e.g., in the case of polymer thin films, cross-link) the patterned liquid inside or immediately after exiting the gap region. The patterned structures are either connected by an intervening web as part of a polymer sheet, or separated into discreet micro-scale structures. Nanostructures (e.g., nanotubes or nanowires) disposed in the polymer become vertically oriented during the EHD patterning process. Segmented electrodes and patterned charges are utilized to provide digital patterning control.

Abstract: A mixing system has a parallel droplet dispenser capable of making droplets of a first working material in the range of 10 nanometers to 10 micrometers, a pump to deliver fluid for the droplets of the first working material and to produce a first emulsion, a compact mixer having low inter-voxel mixing to receive the emulsion and produce a homogenous material, and a dispensing system. A method of dispensing a graded material includes generating droplets of a first working material, the droplets having a size in the range of 10 nanometers to 10 micrometers, adding the droplets of the first working material into a fluid to create a first emulsion, wherein addition of the droplets of the first working material is controlled to create gradient in the emulsion, mixing the first emulsion to create a homogenous, graded mixture, and dispensing the homogenous, graded mixture onto a surface.

Abstract: A system to fabricate hierarchical graded materials includes a reservoir to contain a material to be deposited, a print head connected to the reservoir to allow the print head to receive the material to be deposited, the print head having a mixing section, and an actuator connected to the print head, the actuator configured to actuate the print head in six axes of motion.

Abstract: An atomization device includes a pair of counter-rotating rollers, a fluid source configured to coat at least one of the rollers in a feed fluid, and a baffle unit. The counter-rotation of the rollers stretches the feed fluid into a fluid filament between the two diverging surfaces of the rollers. The stretched fluid filaments break into a plurality of droplets at a capillary break-up point of the feed fluid. The baffle unit introduces a baffle fluid within the interior of the device and the baffle fluid transports formed droplets of the feed fluid from the atomization device. Excess or misguided atomized fluid droplets are collected by the baffle unit and are recycled back into the device for use in later atomization processes. The variation of atomization device parameters allows for the selection of droplets having desired physical parameters.

Abstract: An atomization device including a pair of counter-rotating rollers, a fluid source configured to coat at least one of the rollers in a feed fluid, and a baffle unit. The counter-rotation of the rollers stretches the feed fluid into a fluid filament between the two diverging surfaces of the rollers. The stretched fluid filaments breaking into a plurality of droplets at a capillary break-up point of the feed fluid. The baffle unit introduces a baffle fluid within the interior of the device, the baffle fluid transporting formed droplets of the feed fluid from the atomization device. Excess or misguides atomized fluid droplets are collected by the baffle unit and are recycled back into the device for use in later atomization processes. The variation of atomization device parameters allows for the selection of droplets having desired physical parameters.

Abstract: A method of forming a flexible thermal regulation device having multiple functional layers. The layers of the device are formed using various manufacturing techniques and are then integrated to form a sheet having multiple devices disposed thereon. The individual devices are then formed from the sheet.

Abstract: Aerosols can be created by filament stretching and breaking of Newtonian and non-Newtonian fluids by applying a strain to and stretching the fluid. The fluid is stretched along a strain pathway and forms a fluid filament between diverging surfaces. The stretched fluid filament breaks into droplets that can be harvested to form a mist or aerosol. The aerosol creation systems can include one or more pairs of counter-rotating rollers that are positioned adjacent to each other that stretch the fluid or a pair of pistons that move toward and away from each other to stretch the fluid. Some aerosol creation systems can include multiple pairs of counter-rotating rollers that are positioned in a circular, oval, or linear pattern. The aerosol creation system with multiple pairs of counter-rotating rollers can generate mist is one or more directions and can be positioned between two concentric rings or linearly, among other configurations.

Abstract: A system to fabricate hierarchical graded materials includes a reservoir to contain a material to be deposited, a print head connected to the reservoir to allow the print head to receive the material to be deposited, the print head having a mixing section, and an actuator connected to the print head, the actuator configured to actuate the print head in six axes of motion.

Abstract: A flexible temperature management device that uses powered thermoelectric elements to transfer thermal energy between a user and the environment to thermally regulate the user.

Abstract: A system to fabricate hierarchical graded materials includes a reservoir to contain a material to be deposited, a print head connected to the reservoir to allow the print head to receive the material to be deposited, the print head having a mixing section, and an actuator connected to the print head, the actuator configured to actuate the print head in six axes of motion.

Abstract: A method of forming a flexible thermal regulation device having multiple functional layers. The layers of the device are formed using various manufacturing techniques and are then integrated to form a sheet having multiple devices disposed thereon. The individual devices are then formed from the sheet.