Patents by Inventor David Michalovich

David Michalovich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of for treating inflammatory conditions
    Patent number: 10960032
    Abstract: The invention relates to use of Akkermansia muciniphila, a mucin-degrading bacterial species found in the human gut, for treating undesirable inflammatory activity not caused by any metabolic disorder and/or obesity, especially for example undesirable airway inflammatory activity as seen with asthma.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: March 30, 2021
    Assignee: SCHWEIZERISCHES FORSCHUNGSINSTITUT FÜR HOCHGEBIRGSKLIMA UND MEDIZIN IN DAVOS
    Inventors: Liam O'Mahony, Cezmi A. Akdis, David Michalovich, Edith M. Hessel, James R. Brown, David N. Mayhew, Sorif Uddin
  • USE OF AKKERMANSIA MUCINIPHILA FOR TREATING INFLAMMATORY CONDITIONS
    Publication number: 20200164003
    Abstract: The invention relates to use of Akkermansia muciniphila, a mucin-degrading bacterial species found in the human gut, for treating undesirable inflammatory activity not caused by any metabolic disorder and/or obesity, especially for example undesirable airway inflammatory activity as seen with asthma.
    Type: Application
    Filed: December 3, 2019
    Publication date: May 28, 2020
    Applicant: SCHWEIZERISCHES FORSCHUNGSINSTITUT FUR HOCHGEBRIGSKLIMA UND MEDIZIN IN DAVOS
    Inventors: Liam O'Mahony, Cezmi A. Akdis, David Michalovich, Edith M. Hessel, James R. Brown, David N. Mayhew, Sorif Uddin
  • Use of for treating inflammatory conditions
    Patent number: 10537597
    Abstract: The invention relates to use of Akkermansia muciniphila, a mucin-degrading bacterial species found in the human gut, for treating undesirable inflammatory activity not caused by any metabolic disorder and/or obesity, especially for example undesirable airway inflammatory activity as seen with asthma.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: January 21, 2020
    Assignee: Schweizerisches Forschungsinstitut Fur Hochgebrigsklima Und Medizin In Davos
    Inventors: Liam O'Mahony, Cezmi A. Akdis, David Michalovich, Edith M. Hessel, James R. Brown, David N. Mayhew, Sorif Uddin
  • BIFIDOBACTERIUM LONGUM ABLE TO BENEFICIALLY MODULATE IMMUNE RESPONSE TO RESPIRATORY VIRUS INFECTION
    Publication number: 20200016220
    Abstract: Bifidobacterium longum strains and cell wall fractions isolated from Bifidobacterium longum strains are useful in the prophylaxis or treatment of a respiratory viral infection in a subject. They are also useful in the prophylaxis of a secondary bacterial infection associated with a respiratory viral infection in a subject, especially a subject who is susceptible to respiratory infections.
    Type: Application
    Filed: February 28, 2018
    Publication date: January 16, 2020
    Applicant: Alimentary Health Limited
    Inventors: Barry KIELY, Liam O'MAHONY, David GROEGER, Raymond Alan GRANT, David MICHALOVICH, Edith M. HESSEL, Richard A. WILLIAMSON
  • TREATING RESPIRATORY DISEASES BY TARGETING INTERLEUKIN 4 INDUCED 1 (IL4I1)
    Publication number: 20190135911
    Abstract: Provided herein are methods for treating or preventing a respiratory disease, such as chronic obstructive pulmonary disease (COPD), by reducing or inhibiting interleukin 4 inducible 1 (IL4I1) activity.
    Type: Application
    Filed: April 21, 2017
    Publication date: May 9, 2019
    Inventors: Kathleen M. SULLIVAN, Katherine Kurylo, Paul Redford, Soren Beinke, David Michalovich, Karen Simpson, Edith Hessel
  • USE OF AKKERMANSIA MUCINIPHILA FOR TREATING INFLAMMATORY CONDITIONS
    Publication number: 20180296613
    Abstract: The invention relates to use of Akkermansia muciniphila, a mucin-degrading bacterial species found in the human gut, for treating undesirable inflammatory activity not caused by any metabolic disorder and/or obesity, especially for example undesirable airway inflammatory activity as seen with asthma.
    Type: Application
    Filed: October 5, 2016
    Publication date: October 18, 2018
    Applicant: SCHWEIZERISCHES FORSCHUNGSINSTITUT FUR HOCHGEBRIGSKLIMA UND MEDIZIN IN DAVOS
    Inventors: Liam O'Mahony, Cezmi A. Akdis, David Michalovich, Edith M. Hessel, James R. Brown, David N. Mayhew, Sorif Uddin
  • P13K INHIBITOR FOR TREATMENT OF RESPIRATORY DISEASE
    Publication number: 20160263109
    Abstract: The present invention is directed to compounds and pharmaceutically acceptable salts thereof which are inhibitors of the activity or function of the phosphoinositide 3?OH kinase family (hereinafter PI3K) for use in the treatment or prevention of respiratory infections, the treatment of airway damage, and/or the prevention of airway injury in patients.
    Type: Application
    Filed: October 15, 2014
    Publication date: September 15, 2016
    Inventors: Augustin AMOUR, Julie Nicole HAMBLIN, Edith HESSEL, David MICHALOVICH, Srividya SRISKANTHARAJAH
  • PI3K INHIBITOR FOR TREATMENT OF RESPIRATORY DISEASE
    Publication number: 20160256466
    Abstract: The present invention is directed to compounds and pharmaceutically acceptable salts thereof which are inhibitors of the activity or function of the phosphoinositide 3?OH kinase family (hereinafter PI3K) for use in the treatment or prevention of respiratory infections, the treatment of airway damage, and/or the prevention of airway injury in patients with a PI3K? mutation.
    Type: Application
    Filed: October 15, 2014
    Publication date: September 8, 2016
    Applicant: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Augustin AMOUR, Julie Nicole HAMBLIN, Edith HESSEL, David MICHALOVICH, Srividya SRISKANTHARAJAH
  • vWFA and/or ANTIG domain containing proteins
    Patent number: 8222371
    Abstract: Proteins (INSP141, INSP142, INSP143, and INSP144) identified as anthrax receptor-like proteins containing von Willebrand factor A (vWFA) and Anthrax receptor extracellular (ANT_IG) domains and the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease are described.
    Type: Grant
    Filed: October 28, 2005
    Date of Patent: July 17, 2012
    Assignee: Ares Trading S.A.
    Inventors: Mark Douglas Davies, David Michalovich, Melanie Yorke, Christine Power
  • Defensin Proteins
    Publication number: 20090324562
    Abstract: This invention relates to the novel proteins, termed INSP108 and INSP109, herein identified as members of the defensin family of proteins and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: June 30, 2009
    Publication date: December 31, 2009
    Inventors: Richard Joseph Fagan, David Michalovich, Simon John White, Christine Power, Melanie Yorke
  • Cys-Rich, Cell Surface Glycoproteins
    Publication number: 20090215672
    Abstract: This invention relates to novel proteins, termed INSP206 and INSP208 herein identified as Cys-rich, cell surface glycoproteins, and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: December 7, 2006
    Publication date: August 27, 2009
    Applicant: ARES TRADING S.A.
    Inventors: Christine Power, David Michalovich, Richard James Mitter
  • TGR3-Like Protein Receptor
    Publication number: 20090214548
    Abstract: There are provided proteins containing a domain corresponding to the C-terminal half of a ZP domain similar to that identified in TGF-beta Receptor III and the use of the proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of diseases. In particular, the present invention relates to the use of the disclosed proteins for modulating the activity of proteins belonging to the TGF-beta superfamily.
    Type: Application
    Filed: December 8, 2005
    Publication date: August 27, 2009
    Applicant: Ares Trading S.A.
    Inventors: David Michalovich, Richard James Mitter, Richard Joseph Fagan, Christine Power
  • MAGI POLYNUCLEOTIDES, POLYPEPTIDES, AND ANTIBODIES
    Publication number: 20090192294
    Abstract: MAGI polypeptides, polynucleotides, antibodies, and methods for producing the same by recombinant techniques are disclosed. Also disclosed are methods for utilizing MAGI polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: April 4, 2008
    Publication date: July 30, 2009
    Inventors: DAVID MICHALOVICH, RABINDER KUMAR PRINJHA
  • Beta defensin proteins
    Patent number: 7563767
    Abstract: This invention relates to novel proteins, termed INSP 108 and INSP 109, herein identified as members of the defensin family of proteins and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: January 13, 2004
    Date of Patent: July 21, 2009
    Inventors: Richard Joseph Fagan, David Michalovich, Simon John White, Christine Power, Melanie Yorke
  • vWFA and/or ANT_IG Domain Containing Proteins
    Publication number: 20090104197
    Abstract: This invention relates to novel proteins (herein termed INSP141, INSP142, INSP143, and INSP144), herein identified as anthrax receptor-like proteins containing von Willebrand factor A (vWFA) and Anthrax receptor extracellular (ANT_IG) domains and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: October 28, 2005
    Publication date: April 23, 2009
    Applicant: Ares Trading S.A.
    Inventors: Mark Douglas Davies, David Michalovich, Melanie Yorke, Christine Power
  • Defensin Proteins
    Publication number: 20090042775
    Abstract: This invention relates to novel proteins, termed INSP 108 and INSP 109, herein identified as members of the defensin family of proteins and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: January 13, 2004
    Publication date: February 12, 2009
    Inventors: Richard Joseph Fagan, David Michalovich, Simon John White, Christine Power, Melanie Yorke
  • Secreted Protein Family
    Publication number: 20070274992
    Abstract: This invention relates to a new family of secreted proteins, termed the SECFAM3 family, its family members including the novel human proteins INSP123, INSP124, and INSP125, herein identified as secreted proteins containing a von Willebrand Factor type C (vWFC) domain, and to the use to these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention, and treatment of disease.
    Type: Application
    Filed: April 30, 2004
    Publication date: November 29, 2007
    Inventors: David Michalovich, Iain McKendrick, Richard Fagan, Christine Power, Melanie Yorke
  • Leucine rich repeat containing protein
    Publication number: 20070148655
    Abstract: This invention relates to the novel protein, termed INSP (179), herein identified as a secreted protein, in particular as a member of the leucine rich repeat containing protein family and to the use of this protein and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: February 14, 2005
    Publication date: June 28, 2007
    Applicant: Ares Trading S.A.
    Inventors: David Michalovich, Simon White, Christine Power, Melanie Yorke-Smith
  • MAGI polynucleotides, polypeptides, and antibodies
    Publication number: 20070059721
    Abstract: MAGI polypeptides, polynucleotides, antibodies, and methods for producing the same by recombinant techniques are disclosed. Also disclosed are methods for utilizing MAGI polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: December 21, 2005
    Publication date: March 15, 2007
    Inventors: David Michalovich, Rabinder Prinjha
  • Serine protease
    Publication number: 20060263776
    Abstract: This invention relates to a novel protein, termed INTP039, herein identified as a serine protease, in particular, as a member of the trypsin family of proteins and to the use of this protein and nucleic acid sequence from the encoding genes in the diagnosis, prevention, and treatment of disease.
    Type: Application
    Filed: December 11, 2003
    Publication date: November 23, 2006
    Inventors: Richard Fagan, David Michalovich, Timothy Charles Nugent