Patents by Inventor David Michalovich

David Michalovich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Midkine-like protein
    Publication number: 20060216709
    Abstract: The invention is based on the discovery that the INSP106 protein is a novel splice variant of a known midkine family member (swall|P21741|MK_HUMAN).
    Type: Application
    Filed: December 10, 2003
    Publication date: September 28, 2006
    Inventors: Carmit Levita, Richard Fagan, David Michalovich, Melanie Yorke
  • Serotonin receptor
    Publication number: 20060166310
    Abstract: This invention relates to a protein, termed INPIONCH1, herein identified as a 5-HT3 receptor and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: July 21, 2003
    Publication date: July 27, 2006
    Applicant: Inpharmatica Ltd.
    Inventors: Anna Lobley, David Michalovich, Ilana Stancovski, Kathryn Allen, Janet Allen, Vadym Osypenko, Alison Gurney
  • Molecular cloning of a 7TM receptor (AXOR34) and screening methods thereof
    Patent number: 6881827
    Abstract: AXOR34 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing AXOR34 polypeptides and polynucleotides in diagnostic assays. Further disclosed are screening assays to identify agonists and antagonists of the interaction between AXOR34 and its ligands, NmU-8, NmU-25, and NmU-23.
    Type: Grant
    Filed: August 9, 2002
    Date of Patent: April 19, 2005
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventors: Nabil Elshourbagy, Usman Shabon, Robert S. Ames, Henry S. Sarau, Lisa Vawter, David Michalovich
  • MOLECULAR CLONING OF A 7TM RECEPTOR (AXOR34) AND SCREENING METHODS THEREOF
    Publication number: 20050049188
    Abstract: AXOR34 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing AXOR34 polypeptides and polynucleotides in diagnostic assays. Further disclosed are screening assays to identify agonists and antagonists of the interaction between AXOR34 and its ligands, NmU-8, NmU-25, and NmU-23.
    Type: Application
    Filed: August 9, 2002
    Publication date: March 3, 2005
    Inventors: Nabil Elshourbagy, Usman Shabon, Robert Ames, Henry Sarau, Lisa Vawter, David Michalovich
  • AXOR35, a G-protein coupled receptor
    Publication number: 20040043393
    Abstract: AXOR35 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing AXOR35 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: January 21, 2003
    Publication date: March 4, 2004
    Inventors: Kelly M. Aubart, Derk J. Bergsma, Laura Fitzgerald, Todd L. Graybill, Xiaotong Li, David Michalovich, Dwight M. Morrow, Yuan Zhu
  • Novel compounds
    Publication number: 20030220478
    Abstract: R35 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing R35 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: December 9, 2002
    Publication date: November 27, 2003
    Applicants: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventors: Mahanandeeshwar Gattu, David Michalovich, Alastair Reith, Mark A. Scheideler, Ping Tsui, Paula F. Zaratin
  • Novel compounds
    Publication number: 20030022822
    Abstract: SBSEMN1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing SBSEMN1 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Application
    Filed: March 15, 2001
    Publication date: January 30, 2003
    Inventors: David Michalovich, Trudy Rachel Doe, Philip David Hayes
  • Novel use
    Publication number: 20020183250
    Abstract: The use of HSCLOCK polypeptides and polynucleotides in the design of protocols for the treatment of sleep disorders, jet lag, pathologies that occur in advanced age, among others, and diagnostic assays for such conditions. Also disclosed are methods for producing such polypeptides by recombinant techniques.
    Type: Application
    Filed: November 8, 2001
    Publication date: December 5, 2002
    Inventors: David Malcolm Duckworth, David Michalovich
  • Novel compounds
    Publication number: 20020165351
    Abstract: R35 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing R35 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: October 17, 2001
    Publication date: November 7, 2002
    Inventors: Mahanandeeshwar Gattu, David Michalovich, Alastair Reith, Mark A. Scheideler, Ping Tsui, Paula F. Zaratin
  • SBHWSB2: a new member of the WD40 SOCS box family
    Publication number: 20020155534
    Abstract: SBHWSB2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing SBHWSB2 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Application
    Filed: August 31, 2001
    Publication date: October 24, 2002
    Inventors: David Michalovich, Matthew Alan Sims, Narjis Shaikh
  • Molecular cloning of a 7TM receptor (AxOR34) and screening methods thereof
    Patent number: 6461836
    Abstract: AXOR34 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing AXOR34 polypeptides and polynucleotides in diagnostic assays. Further disclosed are screening assays to identify agonists and antagonists of the interaction between AXOR34 and its ligands, NmU-8, NmU-25, and NmU-23.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: October 8, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventors: Nabil Elshourbagy, Usman Shabon, Robert S. Ames, Henry S. Sarau, Lisa Vawter, David Michalovich
  • AXOR35, a G-protein coupled receptor
    Publication number: 20020137054
    Abstract: AXOR35 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing AXOR35 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: July 20, 2001
    Publication date: September 26, 2002
    Applicant: SmithKline Beecham Corporation & SmithKline Beecham plc
    Inventors: Kelly M. Aubart, Derk J. Bergsma, Laura Fitzgerald, Todd L. Graybill, Xiaotong Li, David Michalovich, Dwight M. Morrow, Yuan Zhu
  • Novel compounds
    Publication number: 20020106722
    Abstract: SBSEMVL polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilising SBSEMVL polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Application
    Filed: January 18, 2001
    Publication date: August 8, 2002
    Inventors: David Michalovich, Philip David Hayes
  • 7TM receptor (AXOR23)
    Publication number: 20020098538
    Abstract: AXOR23 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing AXOR23 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: January 24, 2001
    Publication date: July 25, 2002
    Inventors: Nabil Elshourbagy, Usman Shabon, David Michalovich
  • Novel compounds
    Publication number: 20020065237
    Abstract: SBHWSB1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing SBHWSB1 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Application
    Filed: January 23, 2001
    Publication date: May 30, 2002
    Inventors: David Michalovich, Matthew Alan Sims, Narjis Shaikh
  • Molecular cloning of a chemokine receptor (SBELEVTM)
    Publication number: 20020052330
    Abstract: The SBELEVTM polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing SBELEVTM polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Application
    Filed: March 14, 2001
    Publication date: May 2, 2002
    Inventors: David Michalovich, Nabil Elshourbagy, Usman Shabon
  • Axor10, a g-protein coupled receptor
    Patent number: 6361967
    Abstract: AXOR10 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing AXOR10 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Grant
    Filed: February 11, 1999
    Date of Patent: March 26, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Pankaj Agarwal, Nabil A. Elshourbagy, David Michalovich, Randall Forrest Smith, Lisa Vawter
  • Novel compounds
    Publication number: 20020010324
    Abstract: MAGI polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing MAGI polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: February 21, 2001
    Publication date: January 24, 2002
    Inventors: David Michalovich, Rabinder Kumar Prinjha
  • HKABY60 kinase family polypeptides
    Patent number: 6316239
    Abstract: HKABY60 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HKABY60 polypeptides and polynucleotides in the design of protocols for the treatment of cancer, inflammatory disorders, immune disorders and viral diseases, among others, and diagnostic assays for such conditions.
    Type: Grant
    Filed: May 24, 2000
    Date of Patent: November 13, 2001
    Assignee: SmithKline Beecham plc
    Inventor: David Michalovich
  • SBHWSB2: a new member of the WD40 SOCS box family
    Patent number: 6303333
    Abstract: SBHWSB2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing SBHWSB2 polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Grant
    Filed: November 2, 1998
    Date of Patent: October 16, 2001
    Assignee: SmithKline Beecham p.l.c.
    Inventors: David Michalovich, Matthew Alan Sims, Narjis Shaikh