Abstract: The present disclosure describes a dosing regimen of an IL-10F129S expression construct for treating an inflammatory joint disease (e.g., osteoarthritis) in a subject. Methods are provided for treating an inflammatory joint disease in a subject by injecting a first dose and second dose of a composition comprising an IL-10F129S expression construct into an inflamed joint of the subject according to a dosing regimen wherein the two doses of the expression construct are administered to a subject approximately 150-360 days apart. The present disclosure also provides kits comprising a first and second dose of an IL-10F129S expression construct. The kits may be useful for treating an inflammatory joint disease in a subject.

Abstract: Devices, systems, and methods for releasing a catheter from an implant may include a catheter comprising first and second elongate elements, first and second elongate element lumens, a tissue anchor lumen, apertures corresponding to each of the lumens, and retaining portions between adjacent apertures. The first elongate element may extend out of its lumen through the first elongate element aperture, across the retaining portion transversely with respect to a longitudinal axis, and towards the second elongate element aperture. The first elongate element may then extend into the second elongate element aperture, loop over the second elongate element, and extend back across the retaining portion and into the first elongate element lumen. In some instances, the second elongate element is retracted to uncouple the first and second elongate elements from each other and to open a channel for the release of tethered tissue anchors.

Abstract: A system for oil and gas production includes a drilling, pipeline, or power quality device, a sensor, and a storage device. The storage device has instructions stored thereon that, when executed by one or more processors, cause the one or more processors to perform operations. The operations include receiving first data from the sensor. The operations include determining whether the device is experiencing an event condition based on the first data The operations include generating one or more potential corrective actions responsive to a determination that the device is experiencing the event condition. The operations include calculating a reward value for each of the one or more potential corrective actions. The operations include identifying a first corrective action of the one or more potential corrective actions with a largest or most positive reward value The operations include controlling the device according to the first corrective action.

Abstract: A wellhead bracing system for a subsea well includes a base plate assembly and a wellhead brace assembly. The base plate assembly comprises a top surface, a bottom surface, a base plate aperture, and a plurality of anchor holes. The wellhead brace assembly comprises a vertical plate assembly having a cylindrical shape, a horizontal plate assembly to which the vertical plate assembly is attached, and a vertical support assembly attached to an outer surface of the vertical plate assembly and attached to the top surface of the horizontal plate assembly. Horizontal plate holes of the horizontal plate assembly are configured to attach to studs on the top surface of the base plate to secure the wellhead brace assembly to the base plate assembly. The wellhead bracing system slides onto a wellhead of the subsea well and braces an exterior of the wellhead.

Abstract: A single piece electrical connector for connecting two circuit elements incudes a housing and an interconnection member provided therein with an array of electrically conductive and elastic spring contact elements provided on the interconnection member to interconnect the two circuit elements electrically and mechanically in a stacked or coplanar configuration. In some embodiments, the single piece electrical connector connects to interconnection terminals of each circuit element by the application of a force normal to the surfaces of the circuit elements. In some embodiments, the housing of the connector is configured to apply and maintain the normal force between the elastic spring contact elements of the connector and the interconnection terminals of the circuit elements to form low resistance interconnections therebetween.

Abstract: Disclosed herein are compounds (e.g., pyrrole compounds, carboxy pyrroles, etc.), including pharmaceutical compositions that include one or more of such compounds (e.g., carboxy pyrroles). Also disclosed are methods of making carboxy pyrrole compounds. Also disclosed herein are methods of treating diseases and/or conditions (e.g., inflammation and/or cancer) with the carboxy pyrrole compounds disclosed herein.

Abstract: Disclosed herein are systems, methods, and devices for transaction methods for mobile wallet operations in a casino. Various embodiments are directed to applying funds to a user's mobile wallet by transactions at a kiosk, cage, Peripheral System, or other system of the casino. Embodiments are also directed to applying credit to an electronic gaming machine of the casino. Embodiments are also directed to returning or redeeming credit from an electronic gaming machine of the casino to the user. Embodiments are also directed to transferring credit from a mobile wallet to external funds.

Abstract: A door lock may include a latch bolt head and a blocking pin. The latch bolt head may be configured to move between an extended position and a retracted position to selectively engage a latch head pocket of a door jamb. The latch bolt head may also be configured to move between a first rotational position and a second rotational position, wherein the blocking pin is configured to prevent movement of the latch bolt head from the first rotational position to the second rotational position when the blocking pin is in an engaged position.

Abstract: Rather than randomly selecting neural networks to classify a media file, the conductor can determine which neural network engines (from the conductor ecosystem of neural networks) are the best candidates to classify a particular portion/segment of the media file (e.g., audio file, image file, video files). The best candidate neural network engine(s) can depend on the nature of the input media and the characteristics of the neural network engines. In object recognition and identification, certain neural networks can classify vehicles better than others, while another group of neural networks can classify structures better. The conductor can take out the guess work and construct in real-time an inter-classifier neural network using one or more layers selected from one or more pre-trained neural network, based on attribute(s) of the media file, to classify the media file.

Abstract: A limb support comprises a spar, a limb rest, and a coupler. The spar is configured to be supported from a patient support apparatus and adjustable relative to the patient support and has a longitudinal axis. The coupler includes a release that is selectively actuable to release locking mechanisms to permit adjustment of the limb rest relative to the spar.

Abstract: An approach is provided for distributing a root key to a hardware security module (HSM) of an HSM cluster. A signed first command is transmitted to a source HSM to create a master key. A fingerprint of the master key is received in a response signed by the source HSM using a module signing key hardcoded into the source HSM at manufacturing time. A second command is transmitted to a first HSM to generate an importer key pair. A request is transmitted to the source HSM to create and export a wrapped master key. The master key wrapped with a transport key is received. The wrapped master key is transmitted to the first HSM. The master key is activated in the first HSM.

Abstract: Implementations are directed to receiving a first set of images included in a first video captured by a camera that monitors a human performing a task; processing the first set of images using a first machine learning (ML) model to determine whether the first set of images depicts a gesture that is included in a predefined set of gestures; in response to determining that the first set of images depicts a gesture included in a predefined set of gestures, processing a second set of images included in the first video using a second ML model to determine a first gesture type of the gesture; comparing the first gesture type with a first expected gesture type to determine whether performance of the task conforms to a standard operating procedure (SOP) for the task; and providing feedback representative of a comparison result in a user interface.

Abstract: The present invention relates to a control system of an accessory for animals, wherein the accessory comprises: —a refillable device for spraying an active agent, the device comprising a container for the active agent and a nebulizer body with a controllable spray mechanism; —at least one sensor acquiring measurements relating to the animal wearing the accessory or to the environment thereof; and wherein said control system comprises: —a reception unit for receiving data including first data acquired by the at least one sensor; —a determination unit for calculating a risk of infestation of the animal by a parasite according to the data received and determining a control law of the spray mechanism according to the risk of infestation thus calculated, so as to obtain a determined control law; and—a transmission unit for sending the determined control law to the spray mechanism.

Abstract: Implementations for receiving first user input representative of a first accuracy-to-resource value for an AI model, determining a first training recipe for training of the AI model, the first training recipe including a first set of reduction strategies to be performed during training of the AI model, the first training recipe being determined through genetic search of an initial population to provide an updated population, the first set of reduction strategies being selected from the updated population, providing the first training recipe for training of the AI model to provide a first trained version of the AI model at least partially by executing one or more of pruning and quantization during training of the AI model, and outputting the first trained version of the AI model for inference.

Abstract: Implementations include receiving an image of an object; obtaining a reconstructed image by processing the image through a ML model; obtaining a gradient difference image by comparing the image to the reconstructed image; generating an output image at least partially by suppressing non-significant regions representing non-significant anomalies from the gradient difference image using a non-significant suppression (NSS) map; determining whether an anomaly is depicted in the output image; and in response to determining that an anomaly is depicted in the output image, sending an alert indicating that the object is defective.

Abstract: A system for adaptively controlling traffic control devices having a traffic signal system, a computing network, and a communication system is configured to restrict traffic in one or more directions through a junction and to selectively allow traffic through the restricted directions based, in part, on an identity or action of certain traffic. The traffic signal system is configured to be in communication with the computing network through the communication system. The mobile device is also configured to be in communication with the computing network through the communication system. Then the computing network adaptively controls the traffic signal system using a location of the mobile device.

Abstract: Implementations include actions of receiving an image; extracting a visual HOI and a set of visual embeddings, the visual HOI indicating a subject and an object; obtaining, using a vector library, a set of semantic HOIs and sets of semantic embeddings based on the subject, the object and a set of verbs included in the vector library, each set of semantic embeddings corresponding to a semantic HOI; processing, by a compositional model, the set of visual embeddings to provide a set of transition visual embeddings; processing the sets of semantic embeddings to provide respective sets of transition semantic embeddings; determining a set of scores based on the set of transition visual embeddings and the sets of transition semantic embeddings, each score representing a degree of similarity between the visual HOI and a semantic HOI; and determining at least one predicted HOI represented within the image based on the scores.

Abstract: Implementations include actions of receiving an image, providing a set of features for the image, determining a set of HOIs including one or more HOIs that are potentially represented in the image, providing sets of feature scores by, for each HOI in the set of HOIs, determining, by a first ML model, a set of feature scores for respective features in the set of features, generating, by a second ML model, sets of weights based on the set of HOIs, providing a set of final scores by, for each HOI in the set of HOIs, determining a final score based on a respective set of weights and the set of feature scores, each final score corresponding to a respective HOI in the set of HOIs, and selecting an output HOI for the image from the set of HOIs based on the set of final scores.

Abstract: The present invention relates to a system for controlling an accessory for an animal comprising a device spraying an active agent comprising a spray mechanism and at least one sensor acquiring measurements relating to the animal or its environment, the control system comprising: —a receiving unit which receives initial data acquired by the at least one sensor, —a determination unit which determines a control law for the spray mechanism, according to the received data, by selecting an operating mode (MP1, MP2, MP3, MS) from several modes (MP1, MP2, MP3, MS), each corresponding to a control law respectively encoding a number of activations of the spray mechanism for a predetermined duration and a duration for each activation, and —a sending unit capable of sending the determined control law to the spray mechanism.