Abstract: Preparing a metal-containing solution or gel includes combining a metal oxide and a liquid comprising a polar organic solvent to yield a mixture, wherein the metal oxide comprises hydrogen-bonded molecular chains, and each molecular chain comprises: a metal from Groups 4-6; at least one oxyanion of a main group element from Groups 15 and 16 bound to the metal through a polar covalent bond, wherein the at least one oxyanion is optionally protonated; and at least one water molecule bound to the metal through a polar covalent bond; and heating the mixture to yield a solution or gel comprising the polar organic solvent and the metal. The solution or gel can be acidic.

Abstract: Medication delivery methods, devices and systems are provided. The medication delivery device includes a retractable sheath mechanism connected to a distal end of the device. The retractable sheath mechanism is axially movable between a first position to cover a needle attached to the distal end and a second position to expose the needle with an adjustable protrusion length. The retractable sheath mechanism includes one or more skin sensors disposed on an end surface thereof to detect skin before and during injection. In some cases, a needle carousel is provided to connect to the distal end of the device. The needle carousel supports multiple needle capsules each including a needle.

Abstract: A molecular manufacturing process includes contacting a platform molecule with (i) a biocatalyst and (ii) a chemical catalyst under conditions suitable to produce a value-added chemical.

Abstract: Various systems and methods that enhance an exercise activity performed by a user are described. In some embodiments, a rowing machine is described. The rowing machine includes devices and/or components that can enhance the user experience of a user performing a rowing activity using the rowing machine, such as during a rowing-based exercise class. For example, the rowing machine can include different sensors that capture information associated with a position or movement of a seat of the rowing machine relative to a position or movement of a handle of the rowing machine and utilize the captured information to perform actions associated with the user performing the rowing activity.

Abstract: A limb support comprises a spar, a limb rest, and a coupler. The spar is configured to be supported from a patient support apparatus and adjustable relative to the patient support and has a longitudinal axis. The coupler includes a release that is actuable between a first position permitting movement of the coupler relative to the patient support and a second position preventing movement of the coupler relative to the patient support.

Abstract: Disclosed herein are devices and methods for assessing the surface of a target cardiac tissue and for delivering a tissue anchor to cardiac tissue at a preselected depth within the myocardium in a beating heart procedure. In one variation, an anchor delivery device comprises an elongate body, a tissue anchor disposed within a first longitudinal lumen of the elongate body, and a tissue depth indicator slidable within a second longitudinal lumen of the elongate body. The tissue depth indicator has a first configuration that indicates the boundary of the surface of the target tissue and a second configuration that indicates when the distal tip of the elongate body has been advanced to a preselected depth into the target tissue. In some variations, a tissue depth indicator may also be configured to resist or limit the penetration of the delivery device into tissue after a preselected depth has been reached.

Abstract: Tissue repair systems which use knotless all-suture anchors and have the ability to lock multiple repair sutures within the anchor construct. The anchor construct includes a tension suture wrapped or looped upon itself to create an open eyelet, through which multiple repair sutures originating in soft tissue are passed. The location of the eyelet may be anywhere inside the all-suture anchor or adjacent to the exterior of the anchor body. Tensioning of the tension suture causes the eyelet to restrict movement of the repair sutures and secures them within or against the anchor body.

Abstract: A corner bracket comprising a volume of matter having n pairs of parallel faces, where n is an integer larger than 2; each face of each pair of parallel faces comprising an opening; the openings in the faces of each pair of parallel faces being joined by a cylindrical recess having a longitudinal axis perpendicular to the faces joined by the cylindrical recess; the longitudinal axis of the cylindrical recesses being arranged such that the cylindrical recesses do not intersect each other. The number n can be 3 and the volume of matter can be a cube.

Abstract: An in vitro microfluidic “organ-on-chip” device is described herein that mimics the structure and at least one function of specific areas of the epithelial system in vivo. In particular, a stem cell-based Lung-on-Chip is described. This in vitro microfluidic system can be used for modeling differentiation of cells on-chip into lung cells, e.g., a lung (Lung-On-Chip), bronchial (Airway-On-Chip; small-Airway-On-Chip), alveolar sac (Alveolar-On-Chip), etc., for use in modeling disease states of derived tissue, i.e. as healthy, pre-disease and diseased tissues. Additionally, stem cells under differentiation protocols for deriving (producing) differentiated lung cells off-chips may be seeded onto microfluidic devices at any desired point during the in vitro differentiation pathway for further differentiation on-chip or placed on-chip before, during or after terminal differentiation.

Abstract: A system may monitor usage of a cleaning chemical and indicate when the chemical has expired and needs to be replaced. In some examples, the system includes a reservoir containing the chemical and a sensor associated with the reservoir that can detect user interaction with the chemical in the reservoir. The system may track an amount of time until the chemical in the reservoir is deemed to have expired and provide a user alert indicating expiration of the chemical. The system can control the amount of time remaining until the chemical is deemed to have expired based on the detected addition of the object to the reservoir.

Abstract: A method for simulating conveyors includes receiving conveyor content for each cycle, the conveyor content including over-cycle distributions each specific to a vehicle group at a footprint of each conveyor for a footprint cycle time, determining a cumulative probability, for each footprint cycle time, across all of the footprints of the conveyor, of one or more of the footprints of the conveyor having that cycle time or less, and determining an individual probability, for each footprint cycle time, across all of the footprints of the conveyor, of the conveyor having that cycle time. The method further includes receiving a vehicle dispatch strategy and generating an alert indicating an over-cycle risk for the strategy based on the individual probabilities, and/or performing a discrete event simulation of the conveyors using one of the individual probabilities for each cycle and for each conveyor. Other examples systems and methods are also disclosed.

Abstract: Methods and systems for training one or more neural networks for transcription and for transcribing a media file using the trained one or more neural networks are provided. One of the methods includes: segmenting the media file into a plurality of segments; inputting each segment, one segment at a time, of the plurality of segments into a first neural network trained to perform speech recognition; extracting outputs, one segment at a time, from one or more layers of the first neural network; and training a second neural network to generate a predicted-WER (word error rate) of a plurality of transcription engines for each segment based at least on outputs from the one or more layers of the first neural network.

Abstract: Implementations are described herein for provisioning a device such as a DCN with configuration data for operation on a process automation network using an “out-of-band” communication channel. In various implementations, a temporary out-of-band communication channel may be established between a first and second DCNs. The out-of-band communication channel may be distinct from a process automation network through which the first DCN is to be communicatively coupled with other process automation nodes of a process automation system. Provisioning data may be transmitted from the second DCN to the first DCN over the temporary out-of-band communication channel. The provisioning data may include: information technology (IT) configuration data and operational technology (OT) configuration data. Subsequent to the transmitting, the temporary out-of-band communication channel may be closed.

Abstract: A velocity control-based robotic system is disclosed. In various embodiments, sensor data is received from one or more sensors deployed in a physical space in which a robot is located. A processor is used to determine based at least in part on the sensor data an at least partly velocity-based trajectory along which to move an element comprising the robot. A command to implement the velocity-based trajectory is sent to the robot.

Abstract: An approach is provided for distributing a root key to a hardware security module (HSM) of an HSM cluster. A signed first command is transmitted to a source HSM to create a master key. A fingerprint of the master key is received in a response signed by the source HSM using a module signing key hardcoded into the source HSM at manufacturing time. A second command is transmitted to a first HSM to generate an importer key pair. A request is transmitted to the source HSM to create and export a wrapped master key. The master key wrapped with a transport key is received. The wrapped master key is transmitted to the first HSM. The master key is activated in the first HSM.

Abstract: Implementations are described herein for commissioning a device such as a distributed control node (DCN) for operation with a process automation system (PAS) using a portable setup device (PSD) and an “out-of-band” communication channel. In various implementations, static information conveyed by a passive data store of the DCN may be used to establish an out-of-band communication channel between the DCN and PSD. The out-of-band communication channel may be distinct from a process automation network through which the DCN is to be communicatively coupled with other process automation nodes of the PAS. The DCN may be commissioned to the process automation system by exchanging operational technology (OT) data between the DCN and the PSD via the out-of-band communication channel to enable the DCN to cooperate with one or more of the other process automation nodes on the process automation network to implement an at least partially automated process.

Abstract: Disclosed are 13N-oxytocin molecules, methods of manufacture of 13N-oxytocin molecules and methods of use of 13N-oxytocin molecules in the determination of the distribution and kinetics of 13N-oxytocin molecules after craniofacial or other application methods.

Abstract: A launching catheter for targeting a second vessel from a first vessel includes a catheter including a proximal portion and a distal portion including a needle aperture and a flat rectangular radiopaque marker. The flat rectangular radiopaque marker disappears under fluoroscopy upon rotation to provide information about rotational alignment of the launching catheter. The launching catheter includes a needle configured to extend through the needle aperture. A method of aligning the catheter includes rotating the catheter in a first blood vessel until the marker has a thickness (e.g., minimal thickness) under fluoroscopy. The thickness indicates rotational alignment of the catheter.

Abstract: A formulation for cellulosic materials comprises a polyvinyl alcohol terpolymer comprising a polyvinyl alcohol modified with about 1 mol % to about 10 mol % of a hydrophilic comonomer, and with about 1 mol % to about 5 mol % of a hydrophobic comonomer, and having a degree of hydrolysis of about 92% to about 98%.