Patents by Inventor David Noble
David Noble has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 4935531Abstract: Compounds as described having the partial formula ##STR1## These compounds may have a 5--OH or --OMe group and at the 25- position an isopropylene group substituted by methyl, ethyl or isopropyl.The compounds may be used in agriculture or medicine as antiparasitics, and may be prepared by culturing certain Streptomyces strains, in particular Streptomyces thermoarchaensis NC1B 12015.Type: GrantFiled: March 31, 1988Date of Patent: June 19, 1990Assignee: American Cyanamid CompanyInventors: John B. Ward, Hazel M. Noble, Neil Porter, Richard A. Fletton, David Noble
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Patent number: 4918098Abstract: Compounds are described of formula (I) ##STR1## and salts thereof, wherein R.sup.1 a methyl, ethyl or isopropyl group;R.sup.2 is --H, --OH, substituted --OH or a phosphate ester group and R.sup.3 is --H, or R.sup.2 and R.sup.3 together with the carbon atom to which they are attached represent a >C=0 groupand OR.sup.4 is a group OR.sup.5 as defined above;with the proviso that either R.sup.2 represents a group OR.sup.5 (where OR.sup.5 is an alkoxy group OR.sup.7 in which R.sup.7 represents a C.sub.1-6 alkyl substituted by a halogen atom or C.sub.2-6 alkyl interrupted by --O-- or --S--) or at least one of R.sup.2 and OR.sup.4 is a phosphate ester group or a group OCONR.sup.10 R.sup.11 (where R.sup.10 and R.sup.11 are --H or C.sub.1-4 alkyl).These compounds may be used for controlling insect, acarine, nematode or other pests.Type: GrantFiled: March 11, 1987Date of Patent: April 17, 1990Assignee: American Cyanamid CompanyInventors: Michael V. J. Ramsay, Edward P. Tiley, Oswy Z. Pereira, John B. Ward, Neil Porter, Hazel M. Noble, Richard A. Fletton, David Noble, Derek R. Sutherland
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Patent number: 4918096Abstract: Compounds are described of formula (I) ##STR1## and salts thereof, wherein R.sup.1 represents a methyl, ethyl or isopropyl group; andOR.sup.2 is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms.These compounds may be used for controlling insect, acarine, nematode or other pests.Type: GrantFiled: February 19, 1988Date of Patent: April 17, 1990Assignee: American Cyanamid CompanyInventors: Michael V. J. Ramsey, Brian M. Bain, John B. Ward, Hazel M. Noble, Neil Porter, Richard A. Fletton, David Noble, Derek R. Sutherland, Peter D. Howes
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Patent number: 4916153Abstract: Compounds of formula (I): ##STR1## and salts thereof; wherein R.sup.1 is --H, --OH or substituted --OH and R.sup.2 is --H, or R.sup.1 and R.sup.2 together with the carbon atom to which they are attached represent C.dbd.O, C.dbd.CH.sub.2 or C.dbd.NOR.sup.6 in the E configuration (where R.sup.6 is --H, alkyl or alkenyl);R.sup.3 is --OH or substituted --OH and R.sup.4 is --H, or R.sup.3 and R.sup.4 together with the carbon atom to which they are attached represent C.dbd.O;--A--B-- is --C(CH.sub.3).dbd.CH-- or --C(.dbd.CH.sub.2)CHX-- (where X is Cl or Br) andY is --C(R.sup.8).dbd.CHR.sup.7 -- or --C(.dbd.CH.sub.2)CHXR.sup.7 (where X is Cl or Br, R.sup.7 is methyl, ethyl or isopropyl and R.sup.8 is C.sub.2-8 alkyl or C.sub.7-15 phenalkyl); with the proviso that when --A--B-- is (.dbd.CH.sub.2)CHX--, then Y is--C(C.dbd.CH.sub.2)CHXR.sup.7.These compounds may be used for controlling insect, acarine, nematode or other pests.Type: GrantFiled: March 11, 1987Date of Patent: April 10, 1990Assignee: American Cyanamid CompanyInventors: Brian M. Bain, Paul F. Lambeth, Alison C. Rosemeyer, John B. Ward, Neil Porter, Hazel M. Noble, Richard A. Fletton, David Noble, Derek R. Sutherland, Michael V. J. Ramsay, Edward P. Tiley
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Patent number: 4910219Abstract: Compounds are described of the formula ##STR1## and salts thereof, wherein R.sup.1 is methyl, ethyl or isopropyl;R.sup.2 is --H, --OH or substituted --OH and R.sup.3 is --H, or R.sup.2 and R.sup.3 together with the carbon atom to which they are attached represent C.dbd.CH.sub.2, C.dbd.O or C.dbd.NOR.sup.6 (where R.sup.6 is --H, alkyl or alkenyl and the C.dbd.NOR.sup.6 is in the E configuration);OR.sup.4 is as defined above for OR.sup.5and one of the symbols X represents an epoxide oxygen atom and the other represents an epoxide oxygen atom or a carbon-carbon bond.These compounds may be used for controlling insect, acarine, nematode or other pests.Type: GrantFiled: March 11, 1987Date of Patent: March 20, 1990Assignee: American Cyanamid CompanyInventors: Derer R. Sutherland, John B. Ward, Neil Porter, Hazel M. Noble, Richard A. Fletton, David Noble
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Patent number: 4900753Abstract: Compounds are described of formula (I) ##STR1## and salts thereof, wherein R.sup.1 represents a methyl, ethyl or isopropyl group;R.sup.2 represents a hydrogen atom, a C.sub.1-8 alkyl group or a C.sub.3-8 alkenyl group and the group .dbd.NOR.sup.2 is in the E-configuration;OR.sup.3 is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms.These compounds may be used for controlling insect, acarine, nematode or other pests.Type: GrantFiled: June 5, 1987Date of Patent: February 13, 1990Assignee: American Cyanamid CompanyInventors: Derek R. Sutherland, Michael V. J. Ramsay, Edward P. Tiley, Oswy Z. Pereira, John B. Ward, Neil Porter, Hazel M. Noble, Richard A. Fletton, David Noble
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Patent number: 4898821Abstract: Compounds as described having the partial formula ##STR1## These compounds may have a 5-OH or --OMe group amd at the 25- position an isopropylene group substituted by methyl, ethyl or isopropyl.The compounds may be used in agriculture or medicine as antiparasitics, and may be prepared by culturing certain Streptomyces strains, in particular Streptomyces thermoarchaensis NCIB 12015.Type: GrantFiled: March 25, 1987Date of Patent: February 6, 1990Assignee: American Cyanamid CompanyInventors: John B. Ward, Hazel M. Noble, Neil Porter, Richard A. Fletton, David Noble
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Patent number: 4868742Abstract: A communication bus (14) provides bidirectional data communication between a computer (12) and various peripheral units including input/output processors (18, 20) and a service processor (22). The computer includes a memory control unit (24) which is connected to a memory array (26). A central processor unit (30) is connected for data exchange with the memory control unit (24). Data blocks are transferred through the bus (14) and either originate or terminate at the memory array (26). A peripheral unit, such as the processor (18) transfers a data block by first transferring a header parcel (146) which defines an address, block length and type of function. This is transmitted to the memory control unit (24) which carries out the desired data transfer by sending or receiving sequential data parcels. An interrupt bus (16) connects each of the units of the computer system (10) including the processors (18, 20, 22) and the central processing unit (30).Type: GrantFiled: June 9, 1988Date of Patent: September 19, 1989Assignee: Convex Computer CorporationInventors: Alan D. Gant, David A. Nobles, Thomas M. Jones, Arthur T. Kimmel
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Patent number: 4620275Abstract: A vector processing computer is configured to operate in a pipelined fashion wherein each of the functional units is essentially independent and is designed to carry out its operational function in the fastest possible manner. Vector elements are transmitted from memory, either main memory, a physical cache unit or a logical cache through a source bus where the elements are alternately loaded into the vector processing units. The vector control unit decodes the vector instructions and generates the required control commands for operating the registers and logical units within the vector processing units. Thus, the vector processing units essentially work in parallel to double the processing rate. The resulting vectors are transmitted through a destination bus to either the physical cache unit, the main memory, the logical cache or to an input/output processor.Type: GrantFiled: June 20, 1984Date of Patent: October 28, 1986Inventors: Steven J. Wallach, Thomas M. Jones, Frank J. Marshall, David A. Nobles, Kent A. Fuka, Steven M. Rowan, William H. Wallace, Harold W. Dozier, David M. Chastain, John W. Clark, Robert B. Kolstad, James E. Mankovich, Michael C. Harris, Jeffrey H. Gruger, Alan D. Gant, Harold D. Shelton, James R. Weatherford, Arthur T. Kimmel, Gary B. Gostin, Gilbert J. Hansen, John M. Golenbieski, Larry W. Spry, Gerald Matulka, Gaynel J. Lockhart, Michael E. Sydow
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Patent number: 4574152Abstract: Ternary complexes comprising a 7-[D-5-amino-5-carboxypentanamido] cephalosporin complexed with copper (II) ions and an organic nitrogen base as well as a process for their preparation are described. The complexes may be used in the isolation and/or purification of cephalosporin fermentation products.Type: GrantFiled: January 14, 1983Date of Patent: March 4, 1986Assignee: Glaxo Group LimitedInventor: David Noble
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Patent number: 4529734Abstract: 2-Formyloxymethyl-clavam is described and its use as an antifungal compound against a range of fungi for both medical and horticultural and agricultural use is disclosed. Processes for isolating the compound from fermentations of strains of Streptomyces clavuligerus are described.Type: GrantFiled: November 23, 1981Date of Patent: July 16, 1985Assignee: Glaxo Laboratories LimitedInventors: Eunice J. Napier, James K. Evans, David Noble, Michael Bushell
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Patent number: 4490295Abstract: The invention provides the compound (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]heptane- 2-carboxylic acid and its salts in purified form and pharmaceutical compositions containing them and a process for the purification of such compounds by conversion in aqueous media to the lithium salt of the above acid and precipitation thereof.Type: GrantFiled: May 7, 1980Date of Patent: December 25, 1984Assignee: Beecham Group p.1.c.Inventors: Ian D. Fleming, David Noble, Hazel M. Noble (formerly Gillett), Wilfred F. Wall
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Patent number: 4490294Abstract: The invention provides the compound (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]-heptane -2-carboxylic acid and its salts in purified form and pharmaceutical compositions containing them and a process for the purification of such compounds by conversion in aqueous media to the lithium salt of the above acid and precipitation thereof.Type: GrantFiled: March 20, 1978Date of Patent: December 25, 1984Assignee: Beecham Group p.l.c.Inventors: Ian D. Fleming, David Noble, Hazel M. Noble, Wilfred F. Wall
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Patent number: 4367175Abstract: The invention provides the compound (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]-heptane -2-carboxylic acid and its salts in purified form and pharmaceutical compositions containing them and a process for the purification of such compounds by conversion in aqueous media to the lithium salt of the above acid and precipitation thereof.Type: GrantFiled: May 7, 1980Date of Patent: January 4, 1983Assignee: Glaxo Laboratories LimitedInventors: Ian D. Fleming, David Noble, Hazel M. Noble formerly Gillett, Wilfred F. Wall
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Patent number: 4241915Abstract: A compactly foldable exercise apparatus is provided for performing the exercises of sit-ups and push-ups. An adjustably inclinable board provided with foot engaging means adjacent the forward end thereof is positioned generally above a base associated with track means carrying a pair of opposed handgrips. Locking means slideably engage each handgrip with said track means in a manner to facilitate adjustable spacing between said handgrips and to prevent twisting or tilting movement. The apparatus is adapted for performing sit-ups of varying difficulty of execution based upon the angle of inclination of said board, and is adapted for performing push-ups when said board is lowered to a position substantially parallel to said base.Type: GrantFiled: January 16, 1979Date of Patent: December 30, 1980Inventors: David Noble, Donald Noble
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Patent number: 4189181Abstract: A chair is provided having a seating portion containing a water-filled container formed of a thin flexible film and having a horizontally disposed upper flat surface for the supportive cushioning of the user, and an upright portion having an assembly of 5 to 20 elongated water-filled enclosures disposed in parallel horizontal juxtaposition. The elongated enclosures have a rounded outer contour which provides cushioning to the user's back. The hydrostatic pressure within each elongated water-filled enclosure is between 1" and 4" of water.Type: GrantFiled: April 24, 1978Date of Patent: February 19, 1980Inventors: David Noble, Donald Noble
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Patent number: 4144242Abstract: The invention provides the compound (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]-heptane -2-carboxylic acid and its salts in purified form and pharmaceutical compositions containing them and a process for the purification of such compounds by conversion in aqueous media to the lithium salt of the above acid and precipitation thereof.Type: GrantFiled: December 16, 1976Date of Patent: March 13, 1979Assignee: Glaxo Laboratories LimitedInventors: Ian D. Fleming, David Noble, Hazel M. Noble (formerly Gillett), Wilfred F. Wall