Abstract: An autonomous mobile system comprising: a means of achieving mobility, a means of navigating, a means of providing autonomous power, and a means of providing general purpose computing. In some embodiments, the system comprises a base unit capable of sensing its environment and computing navigation instructions to direct the system to move to particular locations and execute functions as directed by a set of programmed instructions. In some embodiments, two or more time-of-flight (TOF) imaging systems are attached to measure distance to objects in the environment, which may in turn be used by the means of navigating. In some embodiments, a coupling exists on the base unit to attach additional structures and mechanisms. These structures may comprise a means for carrying packages or other items, robotic manipulators that can grab and move objects, interactive audio and video displays for telepresence applications, a means for serving food and drink, etc.

Abstract: Disclosed herein are active agents, compositions containing them, unit dosage forms containing them, and methods of their use, e.g., for treating a metabolic disorder or nonalcoholic fatty liver disease or for modulating a metabolic marker or nonalcoholic fatty liver disease marker.

Abstract: Methods, systems and apparatus, including computer programs encoded on computer storage media, for training an action selection neural network. One of the methods includes receiving an observation characterizing a current state of the environment; determining a target network output for the observation by performing a look ahead search of possible future states of the environment starting from the current state until the environment reaches a possible future state that satisfies one or more termination criteria, wherein the look ahead search is guided by the neural network in accordance with current values of the network parameters; selecting an action to be performed by the agent in response to the observation using the target network output generated by performing the look ahead search; and storing, in an exploration history data store, the target network output in association with the observation for use in updating the current values of the network parameters.

Abstract: A robotic device control system includes a controller in communication with a plurality of hubs, each of the plurality of hubs coupled to one of a plurality of interventional devices. The controller includes a control and an operation mode actuator. The controller is configured to transition between a first operation mode and a second operation mode in response to actuation of the operation mode actuator. In the first operation mode, the control is linked to a first subset of the plurality of hubs such that movement of the control causes a responsive movement of the first subset of the plurality of hubs. In the second operation mode, the control is linked to a second subset of the plurality of hubs such that movement of the control causes a responsive movement of the second subset of the plurality of hubs.

Abstract: A body mountable robot may include a set of stages disposed in a parallel configuration. The body mountable robot may include a set of actuating joints, wherein an actuating joint, of the set of actuating joints, is configured to rotate with respect to a corresponding stage of the set of stages. The body mountable robot may include at least one actuator, wherein the at least one actuator is configured to actuate at least one actuating joint of the set of actuating joints. The body mountable robot may include a set of scissor mechanisms, wherein a scissor mechanism, of the set of scissor mechanisms, that is coupled to the actuating joint, is supported by the corresponding stage, and wherein the scissor mechanism is configured to translate with respect to the corresponding stage.

Abstract: An autonomous or semi-autonomous vehicle can detect an imminent collision according to sensor data and responsively select an action or a sequence of actions to avoid the collision if avoidable, and to reduce or minimize the harm of the collision if unavoidable. An artificial intelligence model may be used to process the sensor data, detect the imminent collision, and select the collision avoidance action or actions, or the harm-reduction or harm-minimization action or actions. For example, when the collision is considered unavoidable, the vehicle may apply the brakes to reduce the vehicle's speed and therefore, the severity of the impact. When the collision is considered avoidable, the vehicle may automatically apply steering to avoid the potential collision, such as when the vehicle is departing a lane and may collide with a vehicle traveling in the same or opposite direction.

Abstract: There is described a system for providing an interface for product personalization by generating or modifying garment patterns and associated code files. The system processes the extracted measurement attributes and user preferences using generative design models and customization data from a control panel of tools at the interface. The system involves an interface to display a visualization of a garment and uses output of a modeling system to support the visualization. The interface has the control panel of tools to customize, modify or generate garment patterns and associated code files.

Abstract: A connection hub includes a housing coupled to a universal serial bus (USB) cable that includes a plug for electronic devices. A housing of the connection hub includes a number (N) of ports and switches. The connection hub includes 1-to-N connections between the USB cable and the N ports, where each of the N ports includes a data line and/or a power line. The switches each include a mechanical component that is movable between a first position that activates a private mode and a second position that deactivates the private mode. A data line of a particular port is disabled when the private mode is activated, and a particular power line of the particular port is enabled when either the private mode is activated and when the private mode is deactivated.

Abstract: A method for transferring carrier ions from an auxiliary electrode comprising a source of carrier ions to an electrode assembly includes transferring carrier ions through a porous electrically insulating material from the auxiliary electrode to members of a unit cell population. The electrode assembly includes a population of unit cells stacked in series in a stacking direction and the porous electrically insulating material, wherein each unit cell includes an electrode structure, a counter-electrode structure, and an electrically insulating separator, the electrode structures, counter-electrode structures and electrically insulating separators have opposing upper and lower end surfaces separated in a vertical direction, and the porous electrically insulating material covers the upper or lower end surface(s) of the electrode or the counter-electrode structure(s) of the members of the unit cell population. The porous electrically insulating material has a porosity in the range of from 20% to 60%.

Abstract: The disclosure features compositions and methods that are useful for the treatment of cancer (e.g., gastrointestinal, colorectal cancers) featuring creatine transporter inhibitors (e.g., ?-Guanidinopropionic acid) in combination with a KRAS inhibitor or another chemotherapeutic agent (e.g., leucovorin (folinic acid-FOL), 5-fluorouracil (F), and irinotecan hydrochloride (IRI), and/or bevacizumab).

Abstract: The present disclosure provides a method of measuring the production of a cytokine in a sample in response to an agonist to determine responsiveness of a patient to immunotherapy. The present disclosure also provides a method of treating a cancer patient with an oncolytic viral therapy when a sample from the patient has a certain level of anti-viral antibodies. Further, the present disclosure describes, in part, an immune competence blood test that allows for one skilled in the art to determine if a tumor is immunoproficient to respond to an immunotherapy.

Abstract: A computer-implemented method for a mirror volume comparison is provided. The computer-implemented method includes executing asynchronous remote mirroring between a primary site and a secondary site, making a first flash copy of first data at the primary site, executing asynchronous remote copying of the first flash copy to a replica at the secondary site, making a second flash copy of second data at the secondary site and performing an on-demand compare of the replica with the second flash copy to verify an accuracy of the asynchronous remote mirroring.

Abstract: In an aspect, a wireless device precodes data based on a space-frequency precoding scheme across a plurality of spatial ports and virtual ports based on frequency over which the data is to be transmitted, and transmits, to a repeater, the space-frequency precoded data via the plurality of spatial ports and layers associated with the virtual ports. In another aspect, the wireless device receives a signal from a repeater comprising data precoded based on a space-frequency precoding scheme across a plurality of spatial ports and virtual ports, and derives separate virtual data streams by applying space-frequency minimum mean square error (MMSE) combining of the received signal across multiple reception ports.

Abstract: Systems, devices, and methods are operable to track usage of a surgical instrument and modify the performance of the surgical instrument based on the prior usage of the surgical instrument. Some surgical instruments are designed to have a limited service life beginning at their first use, or a limit to their overall usage in order to ensure safe use of the sensitive instruments. However, a lack of ability to track usage characteristics when the instrument is separated from an external power supply allows for user abuse and avoidance of such safety mechanisms. Adding a battery or capacitor to the instrument may allow for an ability to track usage when the instrument is separated from an external power supply. Implementing special user prompts, device use ratios, and device use half-life upon powering down of an instrument may additionally be used to prevent circumvention of safety features.

Abstract: Gaming systems and methods that modify one or more symbols based on an accumulation of such symbols at one or more symbol display positions over a plurality of plays of a game.

Abstract: An ultrasonic surgical system includes an ultrasonic instrument configured to seal a vessel and including an ultrasonically-activatable blade and a jaw member pivotably movable with respect to the blade, an endoscope configured to capture video data of a surgical site including the blade and the jaw member, and a processor connected to the endoscope. The processor is configured to process the video data to determine an angle between the blade and the jaw member, determine a desired energy level based on the angle, and provide the desired ultrasonic energy as a feedback to the ultrasonic instrument. The ultrasonic instrument performs a closed-loop control to maintain the desired ultrasonic energy.

Abstract: The present invention relates to a method for determining areas of land, called candidate areas, distinct from buildings and compatible with the installation of photovoltaic panels, the method comprising the following steps: the reception of images seen from the sky of a territory, classifying each image containing an image of at least one candidate area into a first image class, carried out by a trained classification model processing each image of the first class so as to obtain a processed image on which the shape of each candidate area is highlighted, carried out by a trained segmentation model; and characterizing each candidate area by determining, from the shape of the highlighted area, a geometric feature useful for installing photovoltaic panels on the candidate area.

Abstract: A filtration device for a down-flow catalytic hydroprocessing reactor is disclosed. The filtration device may be used in the petroleum and chemical processing industries in catalytic reactions of hydrocarbonaceous feedstocks in the presence of hydrogen, at an elevated temperature and pressure, to remove contaminants from mixed gas and liquid feedstreams to reactor catalyst beds. The filtration device may be provided as a horizontal tray installation at the top of a reactor, whereby feedstream liquid is passed through a filtration media in a radially inward direction from the wall of the reactor to the center of the filtration device and thereafter to the reactor catalyst bed. Among the benefits provided are the minimization of scale and small/fine particulates that reach the catalyst bed below the device, reduced pressure drop through the reactor, even when the filter is completely fouled, and the potential for added catalyst volume due to the reduced need to use catalyst grading materials.

Abstract: A method of extracting precious metal values from a starting material using thiosulphate as a lixiviant. The precious metal values can be recovered from solution using a reductant. The reductant may be a naturally occurring ore including as a component pyrite, chalcopyrite, marcasite and/or pyrrhotite, or can be ferrous sulphate. Sodium hydrosulphide can be added as a scavenging precipitant after the reductant to regenerate thiosulphate. The thiosulphate can be recycled to leach additional precious metal values.

Abstract: Systems and methods are disclosed for training and deployment of machine learning-based models that dynamically translate natural language to database query language, and include automation of training data generation, query representation language, and adaptive model training. A method for generating datasets for a natural language interface to a database includes a database query builder, which receives insights regarding the database, and based at least in part on the database insights builds a plurality of database queries. The method further includes generating a data distribution of natural language queries paired with corresponding database queries by, for each one of the plurality of database queries, pairing the database query to a natural language query and one or more paraphrases of the natural language query, and projecting the data distribution onto a plurality of segmented text distributions and applying one or more control signals to generate an optimal training data distribution.