Patents by Inventor David P. Martin
David P. Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO
Publication number: 20250134105Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).Type: ApplicationFiled: December 19, 2024Publication date: May 1, 2025Applicant: CORTEVA AGRISCIENCE LLCInventors: RONALD J. HEEMSTRA, RONALD ROSS, JR., KYLE A. DEKORVER, KAITLYN GRAY, DANIEL I. KNUEPPEL, PETER VEDNOR, TIMOTHY P. MARTIN, JOSEPH D. ECKELBARGER, JOHN F. DAEUBLE, SR., RICKY HUNTER, DAVID A. DEMETER, TONY K. TRULLINGER, ERICH W. BAUM, ZOLTAN L. BENKO, NAKYEN CHOY, GARY D. CROUSE, FANGZHENG LI, JEFFREY NISSEN, MONICA B. OLSON, MICHELLE RIENER, THOMAS C. SPARKS, FRANK J. WESSELS, MAURICE C. YAP -
Patent number: 12285325Abstract: Absorbable implants for breast surgery that conform to the breast parenchyma and surrounding chest wall have been developed. These implants support newly lifted breast parenchyma, and/or a breast implant. The implants have mechanical properties sufficient to support a reconstructed breast, and allow the in-growth of tissue into the implant as it degrades. The implants have a strength retention profile allowing the support of the breast to be transitioned from the implant to regenerated host tissue, without significant loss of support. Three-dimensional implants for use in minimally invasive mastopexy/breast reconstruction procedures are also described, that confer shape to a patient's breast. These implants are self-reinforced, can be temporarily deformed, implanted in a suitably dissected tissue plane, and resume their preformed three-dimensional shape. The implants are preferably made from poly-4-hydroxybutyrate (P4HB) and copolymers thereof.Type: GrantFiled: July 22, 2022Date of Patent: April 29, 2025Assignee: Tepha, Inc.Inventors: Fabio Felix, Antonio Fosco, David P. Martin, Arikha Moses, Bruce Van Natta, Said Rizk, Simon F. Williams
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Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto
Patent number: 12256738Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).Type: GrantFiled: February 9, 2023Date of Patent: March 25, 2025Assignee: CORTEVA AGRISCIENCE LLCInventors: Ronald J. Heemstra, Ronald Ross, Jr., Kyle A. DeKorver, Kaitlyn Gray, Daniel I. Knueppel, Peter Vednor, Timothy P. Martin, Joseph D. Eckelbarger, John F. Daeuble, Sr., Ricky Hunter, David A. Demeter, Tony K. Trullinger, Erich W. Baum, Zoltan L. Benko, Nakyen Choy, Gary D. Crouse, Fangzheng Li, Jeffrey Nissen, Monica B. Olson, Michelle Riener, Thomas C. Sparks, Frank J. Wessels, Maurice C. Yap -
Publication number: 20250041490Abstract: Resorbable implants, coverings and receptacles comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing molding, pultrusion or other melt or solvent processing method. The implants, or the fibers preset therein, may be oriented. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators. The coverings, receptacles and implants described herein, may be made from meshes, webs, lattices, non-wovens, films, fibers, foams, molded, pultruded, machined and 3D printed forms.Type: ApplicationFiled: October 18, 2024Publication date: February 6, 2025Applicant: Tepha, Inc.Inventors: Simon F. Williams, Said Rizk, David P. Martin, Skander Limem, Kai Guo, Amit Ganatra, German Oswaldo Hohl Lopez
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Patent number: 12151050Abstract: Resorbable implants, coverings and receptacles comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing molding, pultrusion or other melt or solvent processing method. The implants, or the fibers preset therein, may be oriented. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators. The coverings, receptacles and implants described herein, may be made from meshes, webs, lattices, non-wovens, films, fibers, foams, molded, pultruded, machined and 3D printed forms.Type: GrantFiled: August 28, 2020Date of Patent: November 26, 2024Assignee: Tepha, Inc.Inventors: Simon F. Williams, Said Rizk, David P. Martin, Skander Limem, Kai Guo, Amit Ganatra, German Oswaldo Hohl Lopez
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Patent number: 12109100Abstract: Resorbable three-dimensional implants that can be temporarily deformed, implanted by minimally invasive means, and resume their original shape in vivo, have been developed. These implants are particularly suitable for use in minimally invasive procedures for tissue reinforcement, repair of hernias, and applications where it is desirable for the implant to contour in vivo to an anatomical shape, such as the inguinofemoral region. In the preferred embodiment, the implants are made from meshes of poly-4-hydroxybutyrate monofilament that have reinforced outlying borders that allow the meshes to form three-dimensional shapes that can be temporarily deformed. These implants can resume three-dimensional shapes after being temporarily deformed that contour to the host's tissue or an anatomical shape, for example, in the repair of a hernia, and particularly a hernia in the inguinofemoral region.Type: GrantFiled: May 30, 2019Date of Patent: October 8, 2024Assignee: Tepha, Inc.Inventors: Said Rizk, Amit Ganatra, Antonio Fosco, David P. Martin, Simon F. Williams
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Publication number: 20240149523Abstract: Methods to fabricate objects by 3D printing of poly-4-hydroxybutyrate (P4HB) and copolymers thereof have been developed. In one method, these objects are produced by continuous fused filament fabrication using an apparatus and conditions that overcome the problems of poor feeding of the filament resulting from the low softening temperature of the filament and heat creep along the fed filament. Methods using an apparatus including a heat sink, a melt tube, a heating block and nozzle, and a transition zone between the heat sink and heating block, with the melt tube extending through the heat sink, transition zone, and heat block to the nozzle are disclosed. 3D objects are also printed by fused pellet deposition (FPD), melt extrusion deposition (MED), selective laser melting (SLM), printing of slurries and solutions using a coagulation bath, and printing using a binding solution and polymer granules.Type: ApplicationFiled: January 16, 2024Publication date: May 9, 2024Applicant: Tepha, Inc.Inventors: Skander Limem, Reshad Bin Harun, Matthew Dubois, David P. Martin, Said Rizk
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Publication number: 20240130854Abstract: Implants with fillable reservoirs have been developed that are suitable for rhinoplasty, breast reconstruction, ear reconstruction, and replacement, reconstruction or repair of other soft tissues. The implants can be filled with graft material prior to implantation. The implants are preferably made from resorbable polymers, can be tailored to provide different geometries, mechanical properties and resorption rates in order to provide more consistent surgical outcomes. The implants preferably have an interconnected network of unit cells with microporous outer layers and optionally some or all of the unit cells having at least one macropore in their outer layers. The implants can be loaded by injection with microfat, collagen, DCF, cells, bioactive agents, and other augmentation materials, prior to implantation.Type: ApplicationFiled: December 13, 2023Publication date: April 25, 2024Applicant: Tepha, Inc.Inventors: Skander Limem, Fabio Felix, Said Rizk, David P. Martin, Simon F. Williams
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Publication number: 20240082465Abstract: Compositions of P4HB with high purity have been developed. The compositions are prepared by washing P4HB biomass prior to solvent extraction, and precipitating P4HB from solution. The same solvent is preferably used to wash the P4HB biomass, and as a non-solvent to precipitate the polymer from a P4HB solvent solution. The highly pure P4HB compositions are suitable for preparing implants. The implants may be used for the repair of soft and hard tissues.Type: ApplicationFiled: September 13, 2023Publication date: March 14, 2024Applicant: Tepha, Inc.Inventors: David P. Martin, Simon F. Williams, Kai Guo
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Patent number: 11904529Abstract: Methods to fabricate objects by 3D printing of poly-4-hydroxybutyrate (P4HB) and copolymers thereof have been developed. In one method, these objects are produced by continuous fused filament fabrication using an apparatus and conditions that overcome the problems of poor feeding of the filament resulting from the low softening temperature of the filament and heat creep along the fed filament. Methods using an apparatus including a heat sink, a melt tube, a heating block and nozzle, and a transition zone between the heat sink and heating block, with the melt tube extending through the heat sink, transition zone, and heat block to the nozzle are disclosed. 3D objects are also printed by fused pellet deposition (FPD), melt extrusion deposition (MED), selective laser melting (SLM), printing of slurries and solutions using a coagulation bath, and printing using a binding solution and polymer granules.Type: GrantFiled: March 21, 2023Date of Patent: February 20, 2024Assignee: Tepha, Inc.Inventors: Skander Limem, Reshad Bin Harun, Matthew Dubois, David P. Martin, Said Rizk
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Publication number: 20240052528Abstract: Resorbable multifilament yarns and monofilament fibers including poly-4-hydroxybutyrate and copolymers thereof with high tenacity or high tensile strength have been developed. The yarns and fibers are produced by cold drawirg the multifilament, yarns and monofilament fibers before hot drawing the yarns and fibers under tension at temperatures above the melt temperature of the polymer or copolymer. These yarns and fibers have prolonged strength retention in vivo making them suitable for soft tissue repairs where high strength and strength retention is required. The multifilament yarns have tenacities higher than 8.1 grams per denier, and in vivo, retain at least 65% of their initial strength at 2 weeks. The monofilament fibers retain at least 50% of their initial strength at 4 weeks in vivo. The monofilament fibers have tensile strengths higher than 500 MPa. These yarns and fibers may be used to make various medical devices for various applications.Type: ApplicationFiled: October 20, 2023Publication date: February 15, 2024Applicant: Tepha, Inc.Inventors: Amit Ganatra, Fabio Felix, Bhavin Shah, Matthew Bernasconi, Said Rizk, David P. Martin, Simon F. Williams
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Patent number: 11896734Abstract: Resorbable implants comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing, and the fibers may be oriented. Coverings and receptacles made from forms of poly(butylene succinate) and copolymers thereof have also been developed for use with cardiac rhythm management devices and other implantable devices. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators.Type: GrantFiled: March 1, 2019Date of Patent: February 13, 2024Assignee: Tepha, Inc.Inventors: Simon F. Williams, Said Rizk, David P. Martin
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Patent number: 11883279Abstract: Implants with fillable reservoirs have been developed that are suitable for rhinoplasty, breast reconstruction, ear reconstruction, and replacement, reconstruction or repair of other soft tissues. The implants can be filled with graft material prior to implantation. The implants are preferably made from resorbable polymers, can be tailored to provide different geometries, mechanical properties and resorption rates in order to provide more consistent surgical outcomes. The implants preferably have an interconnected network of unit cells with microporous outer layers and optionally some or all of the unit cells having at least one macropore in their outer layers. The implants can be loaded by injection with microfat, collagen, DCF, cells, bioactive agents, and other augmentation materials, prior to implantation.Type: GrantFiled: February 24, 2022Date of Patent: January 30, 2024Assignee: Tepha, Inc.Inventors: Skander Limem, Fabio Felix, Said Rizk, David P. Martin, Simon F. Williams
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Patent number: 11878087Abstract: Resorbable implants comprising poly(butylene succinate) and copolymers thereof have been developed. The implants implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing, and the fibers may be oriented. Coverings and receptacles made from forms of poly(butylene succinate) and copolymers thereof have also been developed for use with cardiac rhythm management devices and other implantable devices. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators.Type: GrantFiled: March 1, 2019Date of Patent: January 23, 2024Assignee: Tepha, Inc.Inventors: Simon F. Williams, Said Rizk, David P. Martin
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Publication number: 20230414829Abstract: Resorbable implants comprising poly(butylene succinate) and copolymers thereof have been developed. The implants implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing, and the fibers may be oriented. Coverings and receptacles made from forms of poly(butylene succinate) and copolymers thereof have also been developed for use with cardiac rhythm management devices and other implantable devices. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators.Type: ApplicationFiled: September 6, 2023Publication date: December 28, 2023Applicant: Tepha, Inc.Inventors: Simon F. Williams, Said Rizk, David P. Martin, Amit Ganatra
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Patent number: 11844879Abstract: Resorbable implants, coverings and receptacles comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing molding, pultrusion or other melt or solvent processing method. The implants, or the fibers preset therein, may be oriented. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators. The coverings, receptacles and implants described herein, may be made from meshes, webs, lattices, non-wovens, films, fibers, foams, molded, pultruded, machined and 3D printed forms.Type: GrantFiled: April 30, 2021Date of Patent: December 19, 2023Assignee: Tepha, Inc.Inventors: Simon F. Williams, Said Rizk, David P. Martin, Skander Limem, Kai Guo, Amit Ganatra, German Oswaldo Hohl Lopez
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Patent number: 11828006Abstract: Resorbable multifilament yarns and monofilament fibers including poly-4-hydroxybutyrate and copolymers thereof with high tenacity or high tensile strength have been developed. The yarns and fibers are produced by cold drawing the multifilament yarns and monofilament fibers before hot drawing the yarns and fibers under tension at temperatures above the melt temperature of the polymer or copolymer. These yarns and fibers have prolonged strength retention in vivo making them suitable for soft tissue repairs where high strength and strength retention is required. The multifilament yarns have tenacities higher than 8.1 grams per denier, and in vivo, retain at least 65% of their initial strength at 2 weeks. The monofilament fibers retain at least 50% of their initial strength at 4 weeks in vivo. The monofilament fibers have tensile strengths higher than 500 MPa. These yarns and fibers may be used to make various medical devices for various applications.Type: GrantFiled: March 9, 2020Date of Patent: November 28, 2023Assignee: Tepha, Inc.Inventors: Amit Ganatra, Fabio Felix, Bhavin Shah, Matthew Bernasconi, Said Rizk, David P. Martin, Simon F. Williams
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Patent number: 11806447Abstract: Compositions of P4HB with high purity have been developed. The compositions are prepared by washing P4HB biomass prior to solvent extraction, and precipitating P4HB from solution. The same solvent is preferably used to wash the P4HB biomass, and as a non-solvent to precipitate the polymer from a P4HB solvent solution. The highly pure P4HB compositions are suitable for preparing implants. The implants may be used for the repair of soft and hard tissues.Type: GrantFiled: January 22, 2019Date of Patent: November 7, 2023Assignee: Tepha, Inc.Inventors: David P. Martin, Simon F. Williams, Kai Guo
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Patent number: 11786632Abstract: Resorbable implants comprising poly(butylene succinate) and copolymers thereof have been developed. The implants implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing, and the fibers may be oriented. Coverings and receptacles made from forms of poly(butylene succinate) and copolymers thereof have also been developed for use with cardiac rhythm management devices and other implantable devices. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators.Type: GrantFiled: March 1, 2019Date of Patent: October 17, 2023Assignee: Tepha, Inc.Inventors: Simon F. Williams, Said Rizk, David P. Martin, Amit Ganatra
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Publication number: 20230226749Abstract: Methods to fabricate objects by 3D printing of poly-4-hydroxybutyrate (P4HB) and copolymers thereof have been developed. In one method, these objects are produced by continuous fused filament fabrication using an apparatus and conditions that overcome the problems of poor feeding of the filament resulting from the low softening temperature of the filament and heat creep along the fed filament. Methods using an apparatus including a heat sink, a melt tube, a heating block and nozzle, and a transition zone between the heat sink and heating block, with the melt tube extending through the heat sink, transition zone, and heat block to the nozzle are disclosed. 3D objects are also printed by fused pellet deposition (FPD), melt extrusion deposition (MED), selective laser melting (SLM), printing of slurries and solutions using a coagulation bath, and printing using a binding solution and polymer granules.Type: ApplicationFiled: March 21, 2023Publication date: July 20, 2023Applicant: Tepha, Inc.Inventors: Skander Limem, Reshad Bin Harun, Matthew Dubois, David P. Martin, Said Rizk