Abstract: Various methods and systems are provided for a drain system for an EGR system of an engine system. In one example, the drain system includes a connector fluidly coupled to each of an intake system, an exhaust system, and a fluid collector, where the connector is positioned vertically below an intake manifold of the intake system and an exhaust passage of the exhaust system and vertically above the fluid collector with respect to a surface on which an engine sits.

Abstract: A differential control apparatus for a self-balancing scooter includes platform interfaces, such as clamping mechanisms, configured to be rigidly connected to respective foot platforms of the self-balancing scooter, and a differential drive coupler mechanically joined to the platform interfaces to impart differential rotational motion thereto in response to a mechanical control input. A rider interface control mechanism is connected to the differential drive coupler to supply the mechanical control input in response to user control actions to control movement of the self-balancing scooter in operation.

Abstract: The present invention relates to a computer implemented system for animating a virtual object or digital entity. It has particular relevance to animation using biologically based models, or behavioural models particularly neurobehavioural models. There is provided a plurality of modules having a computational element and a graphical element. The modules are arranged in a required structure and have at least one variable and being associated with at least one connector. The connectors link variables between modules across the structure, and the modules together provide a neurobehavioural model. There is also provided a method of controlling a digital entity in response to an external stimulus.

Abstract: Provided herein is the use of compounds that modulate the activity of inhibitor of apoptosis proteins (IAPs), alone or in combination with other therapeutic agents, in the treatment of human immunodeficiency virus (HIV). Described herein is the use of IAP antagonists in the treatment of human immunodeficiency virus (HIV) in a mammal, alone or in combination with other therapeutic agents used in HIV therapy. In one aspect, provided herein is a method of treating human immunodeficiency virus (HIV) in an individual in need thereof comprising administering a therapeutically effective amount of at least one inhibitor of apoptosis proteins (IAP) antagonist.

Abstract: Various methods and systems are provided for an exhaust gas recirculation cooler including a plurality of cooling tubes. In one example, an exhaust gas recirculation (EGR) cooler includes a plurality of cooling tubes positioned within a housing of the EGR cooler, each cooling tube of the plurality of cooling tubes extending between and directly coupled to tube sheets of the EGR cooler at ends of each cooling tube, where at least one end of one or more cooling tubes of a first portion of the plurality of cooling tubes, inward of a tube sheet coupled to the at least one end, includes a compliant region, where the first portion is positioned proximate to an exhaust inlet of the EGR cooler.

Abstract: An autonomous vehicle (AV) includes a vehicle computing system including one or more processors configured to receive map data associated with a map of a geographic location, determine, based on the map data, that the AV is on a coverage lane, and, in response to determining that the AV is on the coverage lane, control the AV to maintain at least one functionality associated with a fully-autonomous mode. The map includes (i) a coverage lane where the AV can operate and/or travel under a partially-autonomous mode or a manual mode, and (ii) an AV lane where the AV can operate and/or travel under the fully-autonomous mode. The coverage lane is linked to the AV lane.

Abstract: An expiratory limb for a breathing circuit includes an enclosing wall defining a flexible singular expiratory flow passage between an inlet and an outlet and bounding the flexible singular expiratory flow passage and ambient air. The expiratory limb includes one or more regions of the enclosing wall that made from a material that allows passage of water vapor without allowing passage of liquid water, thereby forming a water vapor flow path from the flexible singular expiratory flow passage to the ambient air through the material. The expiratory limb is configured to allow diffusion of water vapor along the flexible singular expiratory flow passage and dry the flow of expiratory gases between the inlet and the outlet.

Abstract: Provided herein are compounds that modulate the activity of inhibitor of apoptosis proteins (IAPs), compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.

Abstract: A supportive clothing article for a wearable cardioverter defibrillator (WCD), including a belt, the belt including a first end with a first portion of a fastener and a second end with a second portion of the fastener, wherein the belt is structured to fasten around the torso of patient below the chest area of the patient, the belt including a first conductive mesh portion adjacent the first end of the belt or the second end of the belt, two straps, a back portion extending from the belt at an intermediary position on the belt to each of the two straps, the back portion including a conductive mesh, a first support receptacle attached to and extending from the belt and attachable to one of the two straps, and a second support receptacle attached to and extending from the belt and attachable to the other of the two straps.

Abstract: A ventilator device (10) includes a display screen (50, 101) to display a plurality of ventilator functions/modes (or menus) and a plurality of parameters (or sub-menus) associated with at least one of said ventilator functions/modes. A control member, e.g., in the form of a multifunction finger-operable dial (55, 102) is provided to select from the plurality of ventilator functions/modes and/or parameters, the dial being manipulatable in a first manner (e.g., rotation) to scroll between said parameters, and being manipulatable in a second manner (e.g., touching, pressing and/or depressing) to select one of the ventilator functions/modes and/or parameters.

Abstract: A method for receiving autonomous vehicle (AV) map data associated with an AV map of a geographic location and coverage map data associated with a coverage map of the geographic location. The AV map data is associated with an AV lane of a roadway in the geographic location, and the coverage map data is associated with a coverage lane of the roadway in the geographic location. The method includes generating a hybrid map of the geographic location based on the AV map data and the coverage map data and providing hybrid map data associated with the hybrid map for routing of an AV. The hybrid map includes the AV lane linked with the coverage lane of the roadway.

Abstract: A blocking member for an actuator having a movable arm for effecting a quick-make feature, includes for example, an elongated member having a first end and a second end, and wherein a portion of said elongated member being configured so that said blocking member disposed in a first position engages a portion of the movable arm of the actuator to restrain movement of the movable arm, and so that said blocking member disposed in a second position disengages from the portion of the movable arm of the actuator to permit movement of the movable arm.

Abstract: An expiratory limb for a breathing circuit includes an enclosing wall defining a flexible singular expiratory flow passage between an inlet and an outlet and bounding the flexible singular expiratory flow passage and ambient air. The expiratory limb includes one or more regions of the enclosing wall that made from a material that allows passage of water vapor without allowing passage of liquid water, thereby forming a water vapor flow path from the flexible singular expiratory flow passage to the ambient air through the material. The expiratory limb is configured to allow diffusion of water vapor along the flexible singular expiratory flow passage and dry the flow of expiratory gases between the inlet and the outlet.

Abstract: A conduit for a breathing circuit includes a heater associated, at least in part, with a hydrophilic layer. The purpose of the heater is to evaporate any condensed liquid collecting in the conduit, which is first sucked up by the hydrophilic layer. The heated wick reduces the risk of collected water being passed to the patient and causing choking fits or discomfit. It is preferred that the heated wick lies freely in the conduit to settle at low points in the conduit where condensation may collect.

Abstract: A detecting apparatus includes a multi-tier 3D integrated ASIC comprising one or more analog tiers and one or more digital tiers, and a sensor bonded to the multi-tier 3D integrated ASIC. The detecting apparatus includes an electrical substrate and a group of FPGAs or custom data management ASICs. The detecting apparatus also includes a thermal management system, a power distribution system and one or more connectors to transfer data to a data acquisition system configured for radiation spectroscopy or imaging with zero suppressed or full frame readout.

Abstract: A fluid transfer coupling includes a first and second shaft assembly. The first shaft assembly includes a shaft and annular fin attached to shaft, annular fin having one or more internal passages extending therethrough. The or each internal passage connects a center portion of shaft to a radially outwardly facing side of annular fin. The second shaft assembly includes a shaft and annular trough extending radially outwardly of shaft. The first shaft is concentrically accommodated within second shaft with annular fin being accommodated within annular trough. In use, first shaft assembly rotates at a first rotational speed and second shaft assembly rotates at a second rotational speed, with second rotational speed being greater than first rotational speed. The difference between second and first rotational speeds cause a fluid contained within annular trough to be driven radially inwardly through the or each internal passage to center portion of first shaft.

Abstract: Stator vane assembly includes plurality of vanes arranged in circumferential array, radially proximal mounting portion, radially distal mounting portion, and first latching mechanism. Each of plurality of vanes extends radially between radially proximal mounting portion and radially distal mounting portion, with each of plurality of vanes being pivotally mounted between radially proximal mounting portion and radially distal mounting portion. Plurality of vanes is movable between first arrangement allowing gas to flow across vanes, and second arrangement blocking gas flow across vanes. Pivot axis of each of plurality of vanes is offset from the line of aerodynamic center of pressure of vane towards trailing edge of vane, and first latching mechanism holds plurality of vanes in first arrangement. Upon receipt of signal, first latching mechanism releases plurality of vanes so that gas flow through vane assembly causes plurality of vanes to move from first arrangement to second arrangement.

Abstract: A system and method determining a camera pose. The method comprises receiving a first image and a second image, the first and second images being associated with a camera pose and a height map for pixels in each corresponding image, and determining a mapping between the first image and the second image using the corresponding height maps, the camera pose and a mapping of the second image to an orthographic view. The method further comprises determining alignment data between the first image transformed using the determined mapping and the second image and determining a refined camera pose based on the determined alignment data and alignment data associated with at least one other camera pose.

Abstract: A Wearable Cardiac Defibrillator (WCD) system is configured to be worn by a patient who carries a mobile communication device. The mobile communication device has a user interface that is configured to enable the patient to enter wireless inputs. The WCD system includes a communication module that is configured to establish a local comlink with the mobile communication device. The WCD system also includes a tethered action unit that has a user interface configured to enable the patient to enter action inputs. The WCD system can perform some of its functions in response to the action inputs or to the wireless inputs. Since the wireless inputs can be provided from the mobile communication device instead of the action unit, the patient is less likely to attract attention when entering them, and thus exhibit better compliance.

Abstract: Methods of producing multiple protein products from blood-based materials including alpha-1-proteinase inhibitor, gamma globulin, albumin, and other proteins are described herein. The inventive methods include steps of: salt fractionation, chromatography, ultrafiltration, diafiltration, solvent-detergent treatment, and sterile filtration. Advantageously, the inventive methods are simple and produce alpha-1-proteinase inhibitor, gamma globulin, albumin, and other proteins in high yields. The sequence of process steps can be selected to obtain multiple products from various in-process materials, such as supernatants, pastes, chromatography flow-though, and chromatography washes.