Abstract: A conduit for a breathing circuit includes a heater associated, at least in part, with a hydrophilic layer. The purpose of the heater is to evaporate any condensed liquid collecting in the conduit, which is first sucked up by the hydrophilic layer. The heated wick reduces the risk of collected water being passed to the patient and causing choking fits or discomfit. It is preferred that the heated wick lies freely in the conduit to settle at low points in the conduit where condensation may collect.

Abstract: Nanoclusters comprising inorganic nanocrystals and a biodegradable polymer are disclosed. The inorganic nanocrystals have a mean particle size of 1 to 500 nm. The inorganic nanocrystals are contained within a core of the nanoclusters, on the surface of the nanoclusters, contained within a core of the nanoclusters, dispersed throughout the nanoclusters, or a combination thereof. The biodegradable polymer allows the inorganic nanocrystals to be excreted renally over a period of time. The nanoclusters can be used for medical imaging or other biomedical applications.

Abstract: Provided are asynchronous data ingestion and enrichment systems and methods. The systems comprise a plurality of components (e.g., ingestion components, enrichment components, and/or publishing components). Instead of passing data from one component to another, the data is sent to a messaging queue that formats and hold the data until the subsequent component is ready to receive it. Additionally, each component comprises a central microservice and a plurality of instances, the central microservice configured to communicate with each instance of the plurality of instances.

Abstract: A supportive clothing article for a wearable cardioverter defibrillator (WCD), including a belt, the belt including a first end with a first portion of a fastener and a second end with a second portion of the fastener, wherein the belt is structured to fasten around the torso of patient below the chest area of the patient, the belt including a first conductive mesh portion adjacent the first end of the belt or the second end of the belt, two straps, a back portion extending from the belt at an intermediary position on the belt to each of the two straps, the back portion including a conductive mesh, a first support receptacle attached to and extending from the belt and attachable to one of the two straps, and a second support receptacle attached to and extending from the belt and attachable to the other of the two straps.

Abstract: A system and method operate by, while an engine is operating, automatically determining whether the engine is in a designated state for EGR cooler cleaning. The EGR cooler is operably coupled to the engine to receive hot EGR from an exhaust of the engine and to provide cooled EGR to an intake of the engine. The system and method also include, responsive to the engine not being in the designated state, automatically preventing a water pump system from introducing a cleaning liquid into a gas inlet of the EGR cooler.

Abstract: A thermostatic mixing valve including: a first fluid inlet; a second fluid inlet; an outlet; a thermostatic element connected to a return spring and a piston such that movement of the thermostatic element assists with moving the piston, movement of the piston controlling fluid flow from the first fluid inlet and the second fluid inlet to the outlet; a housing containing an overtravel spring, the overtravel spring configured to resist a force applied by the thermostatic element during movement thereof; and a plunger extending into the housing, the plunger configured to engage the overtravel spring, wherein rotating the plunger adjusts the resistance applied onto the thermostatic element from the overtravel spring.

Abstract: A system and method determining a camera pose. The method comprises receiving a first image and a second image, the first and second images being associated with a camera pose and a height map for pixels in each corresponding image, and determining a mapping between the first image and the second image using the corresponding height maps, the camera pose and a mapping of the second image to an orthographic view. The method further comprises determining alignment data between the first image transformed using the determined mapping and the second image and determining a refined camera pose based on the determined alignment data and alignment data associated with at least one other camera pose.

Abstract: A computerized method of routing calls includes the following steps performed by a server computing device: receiving a set of call attributes associated with an incoming call; identifying a document containing call routing instructions corresponding to the call attributes by querying a search index in electronic communication with the server computing device; identifying, based on the document, a set of suitable agents having a skill and a suitable proficiency in the skill by querying an agent skills database in electronic communication with the server computing device; identifying a set of available agents in the set of suitable agents by querying an agent status database in electronic communication with the server computing device; and routing the incoming call to a target agent in the set of available agents, if there is at least one available agent; or a customer waiting queue, if there is no suitable agent.

Abstract: Systems and methods for incorporating social content items into a produced video are provided. The system presents a producer interface to a user that allows the user to query for social content items. The user may then select and arrange social content items in an on-air queue. In an on-air mode, the system generates a broadcast-ready on-air format of the social content items and provides a video stream including the broadcast-ready social content items in the on-air queue to a video production system. The broadcast-ready social content items are incorporated into a produced video by the video production system. The user may navigate through the social content items in the on-air queue while on camera as part of the produced video.

Abstract: Systems, methods, and articles of manufacture provide for community video slot-style gaming such as slot-style games that include a community gaming field and that permit individual players or groups of players to initiate gameplay based on selections of one or more subsets of the community gaming field.

Abstract: An apparatus (e.g., tube sheet) includes a plate piece, a sleeve piece, and a tube piece. The plate piece defines a hole. The sleeve piece has first and second ends; the second end is shaped to fit through the hole for attachment of the sleeve piece to the plate piece. The tube piece also has first and second ends. Inner and outer cross-sectional geometries of the tube piece and the sleeve piece (e.g., in the case of round tubes, inner and outer diameters) are shaped for the first end of the tube piece to fit in the first end of the sleeve piece and to form a continuous interior fluid flow path from the second end of the tube piece through the plate piece when the sleeve piece is disposed in the hole and attached to the plate piece and the tube piece is disposed in the sleeve piece.

Abstract: Provided herein is the use of compounds that modulate the activity of inhibitor of apoptosis proteins (IAPs), alone or in combination with other therapeutic agents, in the treatment of human immunodeficiency virus (HIV).

Abstract: A wearable cardiac defibrillator (“WCD”) system may include a support structure that a patient can wear, an energy storage module that can store an electrical charge, and a discharge circuit that can discharge the electrical charge through the patient so as to shock him or her, while the patient is wearing the support structure. Embodiments may actively take into account bystanders, both to protect them from an inadvertent shock, and also to enlist their help. In some embodiments, the WCD system includes a speaker system and a memory. Prompts have been saved in advance in the patient's own voice, and stored in the memory. In case of an emergency, the prompts may be played by the speaker system in the patient's own voice, and heard by a bystander.

Abstract: In embodiments, a wearable cardiac defibrillation (WCD) system includes one or more flexible ECG electrodes. The WCD system may have a support structure that is dimensioned to be worn so as to press the electrodes towards the body of the patient. The electrodes may be made from appropriate material so as to flex in order to match a contour of the body of the patient. An advantage over the prior art is that the flexible electrode may make better electrical contact with the patient's skin, and therefore provide a better ECG signal for the WCD system to perform its diagnosis.

Abstract: The present invention relates to a computer implemented system for animating a virtual object or digital entity. It has particular relevance to animation using biologically based models, or behavioural models particularly neurobehavioural models. There is provided a plurality of modules having a computational element and a graphical element. The modules are arranged in a required structure and have at least one variable and being associated with at least one connector. The connectors link variables between modules across the structure, and the modules together provide a neurobehavioural model. There is also provided a method of controlling a digital entity in response to an external stimulus.

Abstract: Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor negative allosteric modulators (NAMs), compositions comprising the compounds, and methods of using the compounds and compositions.

Abstract: In embodiments, a wearable medical system (WMS) for an ambulatory patient, which can be a wearable cardioverter defibrillator (WCD) system, analyzes the patient's ECG signal to generate a detection outcome. The WMS also has an ambulatory user interface that outputs a human-visible indication. A programming device, such as a PC, a tablet, etc., establishes a communication link with the WMS during an in-person session with the patient. The programming device may include a programming screen that reproduces the human-visible indication in real time. An advantage can be that the person programming the WMS need not strain to look also at the ambulatory user interface at the time they are looking at the programming device. Another advantage can be that the patient will recognize that he or she is better protected, and have their confidence in the WMS increased, and therefore better comply with wearing the WMS as required.

Abstract: Disclosed herein are embodiments of a wound treatment apparatus with electronic components integrated within a wound dressing. In some embodiments, a wound dressing apparatus can comprise a wound contact layer, an absorbent layer over the wound contact layer, the absorbent layer comprising one or more apertures, a cover layer configured to cover and form a seal over the wound contact layer and the absorbent layer, and an electronics assembly comprising a negative pressure source. A portion of the cover layer overlying the one or more apertures in the absorbent layer can be configured to be compressed within the aperture in the absorbent layer when negative pressure is applied to the wound dressing apparatus. The compressed cover layer can indicate a level of negative pressure below the cover layer. In some embodiments, the wound dressing apparatus can comprise an indicator material layer and a cover layer configured to cover and form a seal over the wound contact layer and the indicator material layer.

Abstract: A thermostatic mixing valve including: a first fluid inlet; a second fluid inlet; an outlet; a thermostatic element connected to a return spring and a piston such that movement of the thermostatic element assists with moving the piston, movement of the piston controlling fluid flow from the first fluid inlet and the second fluid inlet to the outlet; a housing containing an overtravel spring, the overtravel spring configured to resist a force applied by the thermostatic element during movement thereof; and a plunger extending into the housing, the plunger configured to engage the overtravel spring, wherein rotating the plunger adjusts the resistance applied onto the thermostatic element from the overtravel spring.