Patents by Inventor David R. Kaes
David R. Kaes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170304496Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.Type: ApplicationFiled: July 6, 2017Publication date: October 26, 2017Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
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Patent number: 9789223Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.Type: GrantFiled: May 2, 2016Date of Patent: October 17, 2017Assignee: Warsaw Orthopedic, Inc.Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
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Patent number: 9480575Abstract: A spinal implant comprises a first member including a wall that defines a first cavity and a second member including a wall defining a second cavity. At least one first expandable bone graft is disposable within the second cavity. The second member is axially translatable relative to the first member between a first configuration and a second, expanded configuration such that at least a portion of the at least one first graft is disposed within the first cavity and the first cavity includes a substantially void portion. At least one second bone graft has a selective configuration and dimension for disposal within the substantially void portion. Systems and methods are disclosed.Type: GrantFiled: January 25, 2016Date of Patent: November 1, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: Julien J. Prevost, Charles A. Britt, Kyle A. Hess, David R. Kaes, Kelly W. Schlachter, Guobao Wei
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Publication number: 20160250025Abstract: An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.Type: ApplicationFiled: May 9, 2016Publication date: September 1, 2016Inventors: Deger C. Tunc, John Winterbottom, David R. Kaes, Todd Boyce, David Knaack, James Russell, Subhabrata Bhattacharyya
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Publication number: 20160243284Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.Type: ApplicationFiled: May 2, 2016Publication date: August 25, 2016Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
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Publication number: 20160231056Abstract: Methods for treating bulk bone tissue are provided. The methods comprise contacting bulk bone tissue or frozen bulk bone tissue with an effective amount of a supercritical fluid so as to dry the bulk bone tissue. In various embodiments, the supercritical fluid destroys contaminants such that the frozen bulk bone tissue is 99.9% substantially pure. In various embodiments, contaminants removed from the frozen bulk bone tissue include lipids, viruses, bacteria, pyrogens, prions, micro-organisms and/or pathogens. In some embodiments, the supercritical fluid causes a 3 log reduction of bacteria within the frozen bulk bone tissue.Type: ApplicationFiled: February 9, 2015Publication date: August 11, 2016Inventors: Guobao Wei, David R. Kaes, Susan J. Drapeau, Subhabrata Bhattacharyya
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Publication number: 20160166303Abstract: A device for mixing a bone material with a liquid is provided. The device comprises a chamber having a proximal end and a distal end, and the bone material disposed within the chamber, the bone material comprising a coherent mass of milled and lyophilized demineralized bone fibers; and a plunger having at least a portion slidably disposed within the proximal end of the chamber and configured to dispense the bone material mixed with liquid from the distal end of the chamber, when the plunger is in an extended position.Type: ApplicationFiled: November 13, 2015Publication date: June 16, 2016Inventors: Kelly W. Schlachter, Daniel A. Shimko, Kerem N. Kalpakci, Erick Vasquez, David R. Kaes, Subhabrata Bhattacharyya
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Publication number: 20160136329Abstract: A bone material comprising a coherent mass of cartridge milled and demineralized bone fibers is provided, the coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a bone material comprising a lyophilized coherent mass of cartridge milled and demineralized bone fibers is provided, the lyophilized coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a method of making an implantable bone material is provided, the method comprising drying a coherent mass of cartridge milled and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass.Type: ApplicationFiled: November 13, 2015Publication date: May 19, 2016Inventors: Kelly W. Schlachter, Daniel A. Shimko, Kerem N. Kalpakci, Erick Vasquez, David R. Kaes, Subhabrata Bhattacharyya
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Publication number: 20160135954Abstract: A bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of milled and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder on the coherent mass. In some embodiments, a method of implanting a bone material is provided, the method comprising contacting the bone material with a liquid, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass; molding the bone material into a shape to implant the bone material; and implanting the bone material at the target tissue site.Type: ApplicationFiled: November 13, 2015Publication date: May 19, 2016Inventors: Kelly W. Schlachter, Daniel A. Shimko, Kerem N. Kalpakci, Erick Vasquez, David R. Kaes, Subhabrata Bhattacharyya
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Publication number: 20160135962Abstract: A spinal implant comprises a first member including a wall that defines a first cavity and a second member including a wall defining a second cavity. At least one first expandable bone graft is disposable within the second cavity. The second member is axially translatable relative to the first member between a first configuration and a second, expanded configuration such that at least a portion of the at least one first graft is disposed within the first cavity and the first cavity includes a substantially void portion. At least one second bone graft has a selective configuration and dimension for disposal within the substantially void portion. Systems and methods are disclosed.Type: ApplicationFiled: January 25, 2016Publication date: May 19, 2016Inventors: Julien J. Prevost, Charles A. Britt, Kyle A. Hess, David R. Kaes, Kelly W. Schlachter, Guobao Wei
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Patent number: 9333080Abstract: An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.Type: GrantFiled: August 21, 2013Date of Patent: May 10, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: Deger C. Tunc, John Winterbottom, David R. Kaes, Todd M. Boyce, David Knaack, James Russell, Subhabrata Bhattacharyya
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Patent number: 9327052Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.Type: GrantFiled: April 22, 2013Date of Patent: May 3, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: David A. Knaack, John Winterbottom, David R. Kaes, Todd M. Boyce, Lawrence A. Shimp
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Patent number: 9308296Abstract: A tissue treatment apparatus and method for treating biologic tissue has a controller, an enclosure, a reagent supply system, a draining configuration, and a gas relief valve is controlled by the controller. Optionally provided is a gas evacuation assembly, a gas supply unit, a thermal unit for heating or cooling reagents or gases, a sonication unit, any or each operated by the controller. The method provides for programming controller to effect a treatment procedure. In an embodiment of the present application the tissue sample is bone material and the treatment procedure effects demineralization of the bone material.Type: GrantFiled: May 5, 2014Date of Patent: April 12, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: Subhabrata Bhattacharyya, David R. Kaes, Brandon R. Theiss
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Patent number: 9271844Abstract: A spinal implant comprises a first member including a wall that defines a first cavity and a second member including a wall defining a second cavity. At least one first expandable bone graft is disposable within the second cavity. The second member is axially translatable relative to the first member between a first configuration and a second, expanded configuration such that at least a portion of the at least one first graft is disposed within the first cavity and the first cavity includes a substantially void portion. At least one second bone graft has a selective configuration and dimension for disposal within the substantially void portion. Systems and methods are disclosed.Type: GrantFiled: March 13, 2013Date of Patent: March 1, 2016Assignee: Warsaw Orthopedic, Inc.Inventors: Julien J. Prevost, Charles Britt, Kyle Hess, David R. Kaes, Kelly W. Schlachter, Guobao Wei
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Publication number: 20150314043Abstract: A tissue treatment apparatus and method for treating biologic tissue has a controller, an enclosure, a reagent supply system, a draining configuration, and a gas relief valve is controlled by the controller. Optionally provided is a gas evacuation assembly, a gas supply unit, a thermal unit for heating or cooling reagents or gases, a sonication unit, any or each operated by the controller. The method provides for programming controller to effect a treatment procedure.Type: ApplicationFiled: May 5, 2014Publication date: November 5, 2015Applicant: Warsaw Orthopedic, Inc.Inventors: Subhabrata Bhattacharyya, David R. Kaes, Brandon R. Theiss
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Patent number: 9107751Abstract: An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.Type: GrantFiled: January 19, 2007Date of Patent: August 18, 2015Assignee: Warsaw Orthopedic, Inc.Inventors: John Winterbottom, David R. Kaes, Deger C. Tunc, Todd M. Boyce, David Knaack, James Russell, Subhabrata Bhattacharyya
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Patent number: 9034356Abstract: The invention is directed toward porous composites for application to a bone defect site to promote new bone growth. The inventive porous composites comprise a biocompatible polymer and a plurality of particles of bone-derived material, inorganic material, bone substitute material or composite material. In certain embodiments, the porous composites are prepared using a method that includes a supercritical fluid (e.g., supercritical carbon dioxide) treatment. The invention also discloses methods of using these composites as bone void fillers.Type: GrantFiled: January 19, 2007Date of Patent: May 19, 2015Assignee: Warsaw Orthopedic, Inc.Inventors: Lawrence A. Shimp, John Winterbottom, David R. Kaes, Ryan M. Belaney, Subhabrata Bhattacharyya
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Publication number: 20140277480Abstract: A spinal implant comprises a first member including a wall that defines a first cavity and a second member including a wall defining a second cavity. At least one first expandable bone graft is disposable within the second cavity. The second member is axially translatable relative to the first member between a first configuration and a second, expanded configuration such that at least a portion of the at least one first graft is disposed within the first cavity and the first cavity includes a substantially void portion. At least one second bone graft has a selective configuration and dimension for disposal within the substantially void portion. Systems and methods are disclosed.Type: ApplicationFiled: March 13, 2013Publication date: September 18, 2014Applicant: Warsaw Orthopedic, Inc.Inventors: Julien J. Prevost, Charles Britt, Kyle Hess, David R. Kaes, Kelly W. Schlachter, Guobao Wei
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Publication number: 20140121781Abstract: An osteoimplant composite comprising a plurality of particles of an inorganic material, a bone substitute material, a bone-derived material, or any combination thereof; and a polymer material with which the particles are combined. The composite is either naturally moldable or flowable, or it can be made moldable or settable. After implantation, the composite may be set to provide mechanical strength to the implant. The inventive composite have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength required for most orthopedic applications. The invention also provides methods of using and preparing the moldable and flowable composites.Type: ApplicationFiled: August 21, 2013Publication date: May 1, 2014Applicant: WARSAW ORTHOPEDIC, INC.Inventors: Deger C. Tunc, John Winterbottom, David R. Kaes, Todd M. Boyce, David Knaack, James Russell, Subhabrata Bhattacharyya
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Patent number: 8672980Abstract: There is provided an implant retaining device, which has the effect of preventing an intervertebral implant from jutting out of the receiving bed. The implant retaining device generally includes a plate having at least one throughbore to receive a screw, and a screw for securing the plate to the vertebrae. The plate may be dimensioned to cover a portion of the opening of a receiving bed, and thus, need only be secured to a single vertebral body. In an alternate embodiment, the plate may be used during bone fracture correction procedures to prevent a bone screw from backing out of engagement with adjacent bone sections. A method of retaining an intervertebral implant using the device is also provided.Type: GrantFiled: August 24, 2010Date of Patent: March 18, 2014Assignee: Warsaw Orthopedic, Inc.Inventors: John W. Morris, Lawrence A. Shimp, David R. Kaes