Abstract: An enhanced dilator includes a dilator shaft defining a lumen for receiving a functional device (e.g., a puncturing device) therethrough. The dilator shaft includes a proximal portion for manipulation by a user and a distal portion to placement in or near the heart. A dilator hub is coupled to the proximal portion of the dilator shaft and includes a rotational coupling structure for coupling to a corresponding hub of a therapy sheath.

Abstract: A method and system are disclosed for puncturing tissue, comprising a puncture device for puncturing tissue and a supporting member for supporting the puncture device. The puncture device is capable of being insertable within the supporting member and being selectively usable in co-operation therewith during a portion of a procedure for puncturing tissue and wherein the puncture device is usable independently therefrom during another portion of the procedure.

Abstract: The invention relates to binding molecules, such as antibodies, that bind to the chemokine receptor CCR9. More particularly, the invention relates to the treatment of CCR9-mediated diseases or conditions such as inflammatory bowel disease (IBD), and methods for the detection of CCR9, which make use of the binding molecules of the invention.

Abstract: A method and system are disclosed for puncturing tissue, comprising a puncture device for puncturing tissue and a supporting member for supporting the puncture device. The puncture device is capable of being insertable within the supporting member and being selectively usable in co-operation therewith during a portion of a procedure for puncturing tissue and wherein the puncture device is usable independently therefrom during another portion of the procedure.

Abstract: The invention relates to binding molecules, such as antibodies, that bind to the chemokine receptor CCR9. More particularly, the invention relates to the treatment of CCR9-mediated diseases or conditions such as inflammatory bowel disease (IBD), and methods for the detection of CCR9, which make use of the binding molecules of the invention.

Abstract: An enhanced dilator includes a dilator shaft defining a lumen for receiving a functional device (e.g., a puncturing device) therethrough. The dilator shaft includes a proximal portion for manipulation by a user and a distal portion to placement in or near the heart. A dilator hub is coupled to the proximal portion of the dilator shaft and includes a rotational coupling structure for coupling to a corresponding hub of a therapy sheath.

Abstract: Methods, systems, and non-transitory computer readable storage media are disclosed for generating a machine-learning model and encoding ownership information in the machine-learning model. For example, the disclosed system can generate parameters of a machine-learning model utilizing digital content items modified by a filter. The disclosed system can then process digital content items modified by the filter to generate first outputs based on the digital content items being modified by the filter. The disclosed system can also process digital content items unmodified by the filter to generate second outputs based on the digital content items not being modified by the filter. The disclosed system can determine that the second outputs are degraded relative to the first outputs. Accordingly, the disclosed system can determine ownership of the machine-learning model based on detecting that information about the filter is embedded in parameters of the machine-learning model.

Abstract: The invention relates to binding molecules, such as antibodies, that bind to the chemokine receptor CCR9. More particularly, the invention relates to the treatment of CCR9-mediated diseases or conditions such as inflammatory bowel disease (IBD), and methods for the detection of CCR9, which make use of the binding molecules of the invention.

Abstract: Disclosed is a system and a method to use the system that includes a substrate to support a film of liquid helium and an electron subsystem confined by image forces in a direction perpendicular to the surface of the film, a side gate to electrostatically define a boundary of the electron subsystem, a trap gate to electrostatically define an electron trap located outside the boundary of the electron subsystem, and a load gate to selectively open and close access from the electron subsystem to the electron trap, wherein to open access to the electron trap is to apply a first load gate voltage to the load gate to allow the electrons to access the electron trap, and wherein to close access to the electron trap is to apply a second load gate voltage to the load gate to prevent the electrons from accessing the electron trap.

Abstract: Disclosed is a system and a method to use the system that includes a substrate to support a film of liquid helium and an electron subsystem confined by image forces in a direction perpendicular to the surface of the film, a side gate to electrostatically define a boundary of the electron subsystem, a trap gate to electrostatically define an electron trap located outside the boundary of the electron subsystem, and a load gate to selectively open and close access from the electron subsystem to the electron trap, wherein to open access to the electron trap is to apply a first load gate voltage to the load gate to allow the electrons to access the electron trap, and wherein to close access to the electron trap is to apply a second load gate voltage to the load gate to prevent the electrons from accessing the electron trap.

Abstract: Methods, systems, and non-transitory computer readable storage media are disclosed for generating a machine-learning model and encoding ownership information in the machine-learning model. For example, the disclosed system can generate parameters of a machine-learning model utilizing digital content items modified by a filter. The disclosed system can then process digital content items modified by the filter to generate first outputs based on the digital content items being modified by the filter. The disclosed system can also process digital content items unmodified by the filter to generate second outputs based on the digital content items not being modified by the filter. The disclosed system can determine that the second outputs are degraded relative to the first outputs. Accordingly, the disclosed system can determine ownership of the machine-learning model based on detecting that information about the filter is embedded in parameters of the machine-learning model.

Abstract: Disclosed is a system and a method to use the system that includes a substrate to support a film of liquid helium and an electron subsystem confined by image forces in a direction perpendicular to the surface of the film, a side gate to electrostatically define a boundary of the electron subsystem, a trap gate to electrostatically define an electron trap located outside the boundary of the electron subsystem, and a load gate to selectively open and close access from the electron subsystem to the electron trap, wherein to open access to the electron trap is to apply a first load gate voltage to the load gate to allow the electrons to access the electron trap, and wherein to close access to the electron trap is to apply a second load gate voltage to the load gate to prevent the electrons from accessing the electron trap.

Abstract: Disclosed is a system and a method to use the system that includes a substrate to support a film of liquid helium and an electron subsystem confined by image forces in a direction perpendicular to the surface of the film, a side gate to electrostatically define a boundary of the electron subsystem, a trap gate to electrostatically define an electron trap located outside the boundary of the electron subsystem, and a load gate to selectively open and close access from the electron subsystem to the electron trap, wherein to open access to the electron trap is to apply a first load gate voltage to the load gate to allow the electrons to access the electron trap, and wherein to close access to the electron trap is to apply a second load gate voltage to the load gate to prevent the electrons from accessing the electron trap.

Abstract: A method and system are disclosed for puncturing tissue, comprising a puncture device for puncturing tissue and a supporting member for supporting the puncture device. The puncture device is capable of being insertable within the supporting member and being selectively usable in co-operation therewith during a portion of a procedure for puncturing tissue and wherein the puncture device is usable independently therefrom during another portion of the procedure.

Abstract: Data is routed within a data network (8), for example a mobile ad hoc network (MANET), comprising at least one wireless network node (10), typically having a router (11). A processor (18) analyzes characteristics of a wireless link (12ab) between a pair of nodes (10a, 10b) within the network (8). Following such analysis, the processor (18) assigns a link class to the wireless link (12ab), the link class being chosen from a predefined set of link classes. A first link class represents that the link (for example link 12ab) is suitable for carrying one or more types of traffic (for example real-time audio and text), but not suitable for one or more other types of traffic (for example real-time video of a certain quality). A second link class represents that a link (for example link 12ac) is suitable for two or more types of traffic (for example real-time audio and real-time video) including at least one type of traffic (for example real-time video) not supported by the first link class.

Abstract: Data is routed within a data network (8), for example a mobile ad hoc network (MANET), comprising at least one wireless network node (10), typically having a router (11). A processor (18) analyses characteristics of a wireless link (12ab) between a pair of nodes (10a, 10b) within the network (8). Following such analysis, the processor (18) assigns a link class to the wireless link (12ab), the link class being chosen from a predefined set of link classes. A first link class represents that the link (for example link 12ab) 10b is suitable for carrying one or more types of traffic (for example real-time audio and text), but not suitable for one or more other types of traffic (for example real-time video of a certain quality). A second link class represents that a link (for example link 12ac) is suitable for two or more types of traffic (for example real-time audio and real-time video) including at least one type of traffic (for example real-time video) not supported by the first link class.

Abstract: Techniques are disclosed for selecting one or more services and locations for performing a user-requested operation on a file. A user interface can be used to search for files by name, date, content, location, and/or other parameters. The search results can be derived from information stored in a local cache and presented as a list from which the user can select files and perform operations on the selection. The cache can include historical information about each service and location, including a previously observed monetary cost to perform the operation and/or a previously observed amount of time used to perform the operation. A weighted value associated with any given service can be computed based on the historical information in the local cache, the age of the historical information and a cost criterion. The list of services can be ordered by the weighted value.

Abstract: A control system for a model railroad includes a wireless transceiver circuit, associated with a model railroad device, and control software, operable upon a general purpose wireless smart device, comprising programming code for bidirectional wireless communication with the wireless transceiver circuit. The wireless transceiver circuit includes a control circuit, configured for controlling operation of the model railroad device, and a communication unit, configured for bidirectional communication between the wireless transceiver circuit and the general purpose wireless smart device. The control software is configured for allowing user commands entered via the general purpose wireless smart device to control operation of the control circuit.

Abstract: A hierarchical data management tool and user interface that provides an efficient and effective means for an organization to organize both users and their access to a system consisting of a large number of remote sensing locations. Various levels of notifications for specified personnel allow the notified persons to respond to alerts in an efficient manner. Personnel can be hierarchically organized according to their qualifications and proximity to the sensing location/alert type.