Abstract: Polymers can be prepared in solution by continuously distilling solvent from a solution of diacid prepolymers.

Abstract: The claimed invention provides a novel method of preparing 6-O-methyl erythromycin A. The process comprises the steps of reducing the 9-keto group of erythromycin A to form a 9-hydroxy erythromycin A, protecting the 9-, 2'-, and/or 4"-hydroxyl groups of erythromycin A, selectively methylating the 6-position of the 9-hydroxy erythromycin A derivative, deprotecting the hydroxyl groups and oxidizing the 9-hydroxyl to afford 6-O-methyl erythromycin A.

Abstract: The disclosed invention relates to novel 3'-N-O, 9-O-oxime protected, 6-O-alkyl erthyromycin derivatives, a process of preparing the same. The invention also relates to a process of preparing 6-O-alkyl erythromycin A by eliminating the 3'-N-oxide group and 9-O-oxime protecting groups and optionally deprotecting the hydroxy groups at the 2'- and 4"- positions under suitable reaction conditions.

Abstract: The present invention concerns the novel antiobiotic 6-O-methylerythromycin A crystal form I, a process for its preparation, pharmaceutical compositions comprising this compound and a method of use as a therapeutic agent.

Abstract: The present invention provides a process for the preparation of 6-O-methylerythromycin A Form II comprising converting erythromycin A to 6-O-methylerythromycin A and treating the 6-O-methylerythromycin A with a number of common organic solvents or mixtures of common organic solvents.

Abstract: A case forming panel and case structures incorporating the case forming panel, the material of which being a laminate of internal and exterior liners on a flute providing medium of corrugated board having a flute pitch in depth greater than that of "A" flute, the flutes to extend in use substantially vertically, and preferably having a flute pitch of about 54 mm, a flute depth of about 27 mm, and a take up of about 1.54:1.

Abstract: A process for the preparation of 4"-deoxyerythromycins, having the formula: ##STR1## wherein R is H or OH, and R.sup.1 is H or loweralkyl by treatment of the 2'-O-acetyl-4"-imidazolylthionocarbonyl-erythromycin starting material with the radical initiator 4,4'-azobis-(4-cyanovaleric acid), H.sub.3 PO.sub.2 and an organic base in a water-miscible solvent and optionally eliminating the 2'-O-acetyl group. In a preferred embodiment, the water-miscible solvent is an alcohol and the deoxygenation and deacetylation is carried out in one step.

Abstract: An improved snow making machine (10) is described, comprising a housing (14) and a nucleator (18) disposed inside the housing to mix compressed air with pressurized water to generate a wide angle round spray (24) pattern of ice crystal nuclei. An air hydrant heater device (12) is connected in the compressed air line (74) to heat the compressed air so that humidity present in the air will not freeze and render the nucleator inoperative at relatively low operating temperatures. A spray nozzle manifold (24) is mounted annularly around the housing discharge outlet (14A) and supports a plurality of water nozzles (28) that inject a cold water shower into the air flow, which water shower commingles with the ice crystal nuclei to thereby form ice granules as the two travel through the cold ambient air. The snow making machine can be mounted on a tower like support structure that provides for adjusting the discharge direction and tilt angle of the discharge outlet from a ground level elevation.

Abstract: A method for the preparation of D-chiro-inositol from kasugamycin, comprising the steps of:(a) reacting kasugamycin with an acetylating agent to form a crude hexa-acetate intermediate;(b) purifying the crude intermediate to form purified hexa-acetate intermediate;(c) deacetylating the purified intermediate to form D-chiro-inositol; and(d) isolating the D-chiro-inositol.The method permits efficient, large-scale preparation of D-chiro-inositol without the need for extensive chromatographic purification of the final D-chiro-inositol product.

Abstract: A process for clarifying an alkoxylated product mixture produced using a calcium-based catalyst wherein the product mixture is heated to a temperature of from about 80.degree. C. to about 175.degree. C. to produce a filtration feed, the filtration feed being passed through a filter medium comprising material possessing polar groups to produce a clarified filtrate, the filtration feed being passed through the filter medium within about 5 days of being prepared, the filtration feed being passed through the filter medium until the desired degree of clarification is obtained, the temperature of the clarified filtrate being less than about 30.degree. C. but above the pour point of the clarified filtrate.

Abstract: A method of processing a lithographic printing plate which comprises the steps of exposing, developing and baking the plate, in which a pre-baking liquid is applied to the plate prior to the baking step, and which is not tacky, has a long storage life, and does not require rinsing with water after baking. The pre-baking liquid includes one or more of a sulphosuccinamate or sulphosuccinate and a type and present in an amount sufficient to form a non-water soluble baked coating on the developed plate which acts as an effective barrier to contaminating material tending to come into contact with the developed areas of the plate during the baking step, and which has no adverse reaction with the image and non-image areas and allows the plate to be baked, and thereby to improve the durability of the processed plate for use on a press. The baked coating is removed subsequently by an alkaline solution.

Abstract: The present invention discloses an apparatus with entry, filling and sealing, and exit chambers through which a carriage holding alkali metal containers may be transferred. The drive for the carriage in each chamber is cantilevered to facilitate transfer between chambers, and lateral movement of the carriage with the respect to the direction of transfer is restricted in the filling and sealing chamber. A method of filling containers with molten alkali metal is also disclosed in which the ambient gas pressure is reduced and then raised to reduce quantities of unwanted gas in the alkali metal.

Abstract: Aminodeoxy derivatives of 3-deoxy-D-manno-2-octulosonic acid (KDO) are potent inhibitors of bacterial enzymes and a novel class of antibacterial agents.

Abstract: Derivatives of 3-deoxy-D-manno-2-octulosonic acid (KDO) are potent inhibitors of bacterial enzymes and a novel class of antibacterial agents.

Abstract: In a clutch or brake mechanism of the type comprising two parts in coaxial relationship and an armature co-rotatably coupled with one of the parts and movable under magnetic forces for frictionally engaging the other part, a resilient restoring member for biassing the armature out of engagement with the other part comprises a continuous planar loop having two lobe portions which engage lugs bent from the plane of the armature and interconnecting portions which engage shoulders provided on said one part.