Abstract: A tactical belt or belt accessory system comprising an integral single layer strap having a two opposite ends, a top edge and a bottom edge, and at least one row of a plurality of openings distributed lengthwise along the strap between the two opposite ends, the openings being separated by links that are an integral part of the single layer strap, the openings configured to facilitate attachment of MOLLE-compatible accessories along a horizontal axis or a vertical axis without skipping any of the links.

Abstract: Extrusion techniques for reducing bow of an extrudate formed from a ceramic forming mixture. Velocities of an outer surface of the extrudate are measured at a plurality of peripherally spaced measurement locations. The velocities are compared to determine whether there is a velocity bias, and the comparison is used to selectively alter the flow of the ceramic forming mixture.

Abstract: In some embodiments, the early feasibility assessment (EFA) system generates a set of quantitative systems pharmacology (QSP) models using rule-based reasoning systems to efficiently assess the feasibility of therapeutic drug candidates. With each QSP model, the EFA system provides sets of parameters for the user to easily contrast and compare various scenarios to explore risk and uncertainty of developing the therapeutic drug candidate, while high-performance computing provides near real-time simulation of the scenarios. The EFA system performs 1-dimensional or 2-dimensional scans of parameters and output feasibility criteria including, for example, maximum inhibition, activation, and target engagement. The assessment results and key parameters values can be presented via a user interface of the EFA system which allows user interactions with, for example, dose-response and pharmacokinetic and pharmacodynamic (PK/PD) plots.

Abstract: The present invention provides the use of lipocalin 2 (LCN2) as a biomarker for IL-17 mediated diseases and for monitoring the response of a patient to anti-IL-17 therapy.

Abstract: Disclosed herein include systems, devices, computer readable media, and methods for subsampling flow cytometric event data. First and second flow cytometric event data can be transformed into a lower-dimensional space, associated with a plurality of bins, and assigned to a first bin and a second bin. Subsampled flow cytometric event data comprising the first flow cytometric event data can be generated. The subsampled flow cytometric event data can comprise the second flow cytometric event data if the first bin and the second bin are different. The subsampled flow cytometric event data may not comprise the second flow cytometric event data if the first bin and the second bin are identical.

Abstract: Systems, methods, and computer-readable media provide techniques for on-demand access to object data hosted in distributed object storage. A query is received for the distributed object storage database, wherein the distributed object storage database includes first object data stored in a first data center at a first geographical location, and second object data stored in a second data center at a second geographical location. It is determined that the query is for at least a portion of the first object data stored by the first data center. The query is transmitted to a first computing device in the first data center. Results are received from the first computing device for the query, and the results are provided in response to the received query.

Abstract: A conveyor assembly includes an extendable conveyor, a cradle configured to at least partially receive the extendable conveyor, a first conveyor that is movable between a first position and a second position, the first conveyor configured to receive a material from a first source, and second conveyor configured to receive a material from a second source. The extendable conveyor may be configured to pivot with respect to the cradle.

Abstract: A syringe assembly including a syringe barrel having a first end, a second end, and a sidewall extending therebetween defining a chamber is disclosed. The syringe assembly includes a stopper disposed within the chamber of the syringe barrel and a plunger rod having an inner member engaged with the stopper and an outer member adapted for telescopic movement with respect to the inner member. The plunger rod is transitionable from a collapsed position, in which a portion of the inner member is nested within the outer member, to an extended position, in which the same portion of the inner member extends outside the outer member. The syringe assembly also includes a stop member configured for cooperation with a portion of the syringe barrel, upon relative movement of the outer member with respect to the inner member, to limit the outward travel of the plunger rod from the syringe barrel.

Abstract: An adaptive fifth generation (5G) communications system includes an adaptive 5G tower; a first adaptive 5G site coupled by a dedicated link with the adaptive 5G tower; and a second adaptive 5G site coupled by a direct link with the first adaptive 5G site. The direct link may be established by the first adaptive 5G site and couples the second adaptive 5G site with the adaptive 5G tower. Data signals may be communicated between the adaptive 5G tower and the second adaptive 5G site via the direct link and the dedicated link. Usage of the direct link is accounted for in a blockchain master ledger. The blockchain master ledger corresponds to an adaptive 5G model and may be separately maintained by each of the adaptive 5G tower, the first adaptive 5G site, and the second adaptive 5G site. The master ledger may include relay, processing, path, power, and transaction layers.

Abstract: A medical device that includes a body and a polymer matrix over the body. The polymer matrix includes a plurality of fibers defining a plurality of pores to permit tissue growth therethrough. The medical device includes a bio-adhesive coating at least partially covering the polymer matrix.

Abstract: A method of making a semiconductor device is provided for depositing, patterning, and developing photoresist (1703, 1704) on an underlying layer located on a backside of a wafer having a frontside on which an integrated circuit die are formed over a shared wafer semiconductor substrate and arranged in a grid, thereby forming a patterned photoresist mask with a unique set of one or more openings which are used to selectively etch the underlying layer to form, on each integrated circuit die, a unique die mark identifier pattern of etched openings in the underlying layer corresponding to the unique set of one or more openings in the patterned photoresist mask (1705), where the patterned photoresist mask is removed (1706) from the backside of the wafer before singulating the wafer to form a plurality of integrated circuit devices (1708) which each include a unique die marking.

Abstract: A filter monitoring device for an air flow system is described herein, which comprises a circuit board comprising a first pressure measurement component and a second pressure measurement component, and including hardware and software configured to communicate pressure measurements to a remote computer. The device also includes a sensor comprising a first pressure sensor component comprising a first tube having a first end portion configured to be connected to the circuit board and a second end portion configured to be connected to a first location in the air flow system upstream from and external to a filter media compartment, and a second pressure sensor component comprising a second tube having a first end portion configured to be connected to the circuit board and a second end portion configured to be connected to a second location in the air flow system downstream from and external to the filter media compartment. Corresponding systems and methods also are disclosed.

Abstract: Embodiments of a crimping device for crimping a radially expandable and compressible prosthetic valve are disclosed. A crimping device can comprise a housing configured to receive a prosthetic valve in a radially expanded state. The housing member can include a funnel segment and an outlet in communication with the funnel segment. The crimping device can further comprise an actuator rotatably coupled to the housing, wherein rotation of the actuator relative to the housing causes the prosthetic valve to move axially through the funnel segment such that at least a portion of the prosthetic valve compresses radially by engagement with the funnel segment and exits the crimping device via the outlet.

Abstract: A bypass plunger includes a plunger body that includes a head portion located at one end of the plunger body and a tail portion located at an opposite end of the plunger body. The head portion includes at least one flow port, and the tail portion includes at least one passageway. A valve component is disposed within an internal bore of the plunger body and is moveable between an open position and a closed position. At least one plug is located within a respective one of the flow ports and/or a respective one of the passageways, and is configured to reduce or prevent flow through the respective flow port or the respective passageway.

Abstract: Devices, systems and methods are described herein to provide improved treatment of a tricuspid valve. Such treatment may include tricuspid valve replacement, which may include providing a prosthetic tricuspid valve within the tricuspid valve annulus. Delivery systems for delivering the prosthetic tricuspid valve to the tricuspid valve annulus are disclosed herein. Treatment may also include repair of the tricuspid valve.

Abstract: A portable mirror therapy device comprises a stiff divider panel attached to a base unit which supports the divider panel in an upright position to define two adjacent limb receiving spaces at opposite sides of the divider panel. A mirror is mounted on one face of the divider panel. A clamp, indicated generally by the reference numeral mounted at a lower end of the divider panel cooperates with an underside of the base unit for securing the base unit on a support such as a table or worktop. An exercise apparatus is mounted on the device and includes a limb engaging member, which in this case comprises a handle at a mirror side of the divider panel. The exercise apparatus is a resistance load training system and comprises a load cord extending from the handle to an associated resistance element mounted within a housing on an opposite side of the divider panel to the mirror.

Abstract: A method of assembling a display area includes selecting a first tile from a plurality of tiles, each tile of the plurality of tiles includes a predetermined parameter and a plurality of microLEDs defining a plurality of pixels. The selecting the first tile based on a value of the predetermined parameter of the first tile. The method includes selecting a second tile from the plurality of tiles based on a value of the predetermined parameter of the second tile. The method further includes positioning the first tile and the second tile into an array defining at least a portion of the display area. A first edge of the first tile facing a second edge of the second tile. A display device including the display area assembled by the method is also provided.

Abstract: An adaptor for a respiratory assistance system delivers aerosols to a patient. The adaptor is lightweight with a small footprint to increase patient comfort. The adaptor has a nozzle and a sealing mechanism to maintain pressure therein regardless of whether the nozzle is inserted into the adaptor. The adaptor is configured to connect to medical tubing and a medicament delivery device.

Abstract: A system and method for optimizing advertisements for display to users comprising receiving a request for an advertisement wherein the request comprises information about a user to whom the advertisement is to be displayed; determining at least one community of which the user is a member; determining a conditional probability that the user will interact with the advertisement; responsive to the conditional probability exceeding a threshold, determining community data to present with the advertisement and providing for display to the user the advertisement and the community data; responsive to the providing of the advertisement, receiving an indication of activity at a client system related to the advertisement or community data; and storing the indication in a storage medium.