Abstract: A method and system for non-invasive detection of a living subject's blood oxygen saturation is disclosed herein. A system, method, and apparatus utilizes an imaging RGB/infrared sensor and an active two-color light source for detecting blood oxygen saturation (SpO2) of a living subject in a non-contact manner. The system comprises a non-contact light source comprising red light or infrared light; an imaging sensor; a processor; and a user interface.

Abstract: The present invention relates to a new class of fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.

Abstract: Introduced here is an artificial intelligence system designed for machine learning. The system may be based on a neuromorphic computational model that learns spatial patterns in inputs using data structures called Sparse Distributed Representations (SDRs) to represent the inputs. Moreover, the system can generate signatures for these SDRs, and these signatures may be used to create definitions of classes or subclasses for classification purposes.

Abstract: An implantable medical device includes a first component including a first material, a second component including a second material, and a fiber matrix including a plurality of fibers. The fiber matrix joins the first component to the second component. The fiber matrix includes a first a first portion connected to the first component, and a second portion connected to the second component. The first portion of the fiber matrix is interpenetrated with, and mechanically fixed to, the first material. The first portion of the fiber matrix directly contacts the first material.

Abstract: A method and an apparatus for characterising a sample comprising particles is disclosed. The method comprises performing a first measurement on the sample using a first particle characterisation technique; flowing the sample from the first particle characterisation technique to a particle separating device; separating the sample with the particle separating device; and performing a second measurement on the separated sample. The apparatus is configured to perform the method, and comprises a measurement system for performing measurements according to a first particle characterisation technique and a particle separating device for separating samples comprising particles.

Abstract: The present disclosure provides communication systems and devices for use in noise environments, such as during magnetic resonance imaging (MRI). In some embodiments, a communication headrest is provided that consists of a headrest that supports a patients' head, an optional bone conduction microphone, and one or more vibration actuators. The headset makes contact with noise-isolating earplugs worn by the subject such that vibrations generated by the vibration actuators are transferred through the earplug, via acoustic conduction, to enable the patient to hear audio content while the earplugs provide passive noise protection by occluding the ear canal.

Abstract: Systems and methods for energy storage system are provided. The system includes a particle regeneration subsystem for applying electrical energy to regenerate metallic particulate fuel; a fuel storage subsystem for storing metallic particulate fuel, the fuel storage subsystem in fluid communication with the particle regeneration subsystem; and a power generation subsystem for producing electrical energy from the metallic particulate fuel, the power generation subsystem in fluid communication with the fuel storage subsystem; a bearer electrolyte for transporting the metallic particulate fuel through the particle regeneration subsystem, the fuel storage subsystem and the power generation subsystem; and a control unit configured to independently control flow of the bearer electrolyte between the particle regeneration subsystem and the fuel storage subsystem, and the fuel storage subsystem and the power generation subsystem.

Abstract: An electronic gaming machine includes a display, a credit input mechanism, and a processor programmed to perform operations comprising: (i) determining, during a wagering game initiated in response to receiving a credit wager, that a replay trigger condition is satisfied, the wagering game including a plurality of reels; (ii) initiating, in response to the replay trigger condition, a replay bonus game; (iii) determining a number of replays for use in the replay bonus game; (iv) generating a set of symbols for the plurality of reels for each of the number of replays including an award amount associated with the set of symbols; (v) serially displaying, on the display each of the sets of symbols for each of the number of replays; and (vi) awarding a total award amount including the sum of each award amount for each of the sets of symbols.

Abstract: An adaptor for a respiratory assistance system delivers aerosols to a patient. The adaptor is lightweight with a small footprint to increase patient comfort. The adaptor has a nozzle and a sealing mechanism to maintain pressure therein regardless of whether the nozzle is inserted into the adaptor. The adaptor is configured to connect to medical tubing and a medicament delivery device.

Abstract: Described are antibodies that specifically bind to the Axl protein and inhibit the interaction between Axl and the Axl-ligand, Gas6. Also disclosed are methods for the production and use of the anti-Axl antibodies.

Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.

Abstract: Disclosed are improved methods for manufacturing large-scale populations of robust, highly pure, and functional T regulatory cells (Tregs). Also disclosed are expanded Treg populations, cryopreserved Treg populations and methods and uses of these cells in compositions formulated for treating one or more mammalian diseases, including, for example, treatment, prophylaxis, and/or amelioration of one or more symptoms of a human neurodegenerative disorder. In particular, the compositions and methods provided herein find clinical use in the treatment and amelioration of one or more symptoms of amyotrophic lateral sclerosis (ALS), Alzheimer's disease, and other neurological diseases and disorders.

Abstract: Techniques for routing a user command to a speechlet and resolving conflicts between potential speechlets are described. A system determines an intent of an input command. The system also receives context information associated with the input command. The system determines speechlets (e.g., speechlets and/or skills) that may execute with respect to the input command given the intent and the context data. The system then determines whether conditions of routing rules, associated with the speechlets, are satisfied given the context data. If the conditions of only one routing rule are satisfied, the system causes the speechlet associated with the routing rule to execute with respect to the input command. If the conditions of more than one routing rule are satisfied, the system may determine a speechlet to execute with respect to the input command based on the speechlets' priorities in a list of speechlets and/or based on potential output data provided by the speechlets.

Abstract: Disclosed are embodiments for injecting sidecar proxy capabilities into non-sidecar applications, allowing such non-sidecar applications to communicate with a service mesh architecture. In an embodiment, a method comprises receiving a request to instantiate a proxy for a non-sidecar application at a service mesh gateway (SMG). The SMG then instantiates the proxy in response to the request and broadcasts network information of the non-sidecar application to a mesh controller deployed in a containerized environment. Finally, the SMG (via the proxy) transmits data over a control plane that is communicatively coupled to the mesh controller.

Abstract: This disclosure relates to a data storage device. A data port transmits data between a host computer system and the data storage device over a data channel. The device repeatedly broadcasts advertising packets over a wireless communication channel different from the data channel. Each advertising packet comprises a random value and a message authentication code calculated based on the random value and an identity key. The identity key is readable by a device to be connected and in proximity of the data storage device out of band of the data channel and the communication channel. The identity key enables the device to be connected to verify the message authentication code based on the random value and the identity key to thereby authenticate the data storage device.

Abstract: One variation of a method for autonomously training animals to respond to oral commands includes: prompting a user to select a training protocol; prompting the user to record a first audio clip of the user reciting a voice command associated with a target pose within the training protocol, the user affiliated with the animal; accessing a video feed recorded by an optical sensor during a first training session; in the video feed, detecting the animal within a working field; while the animal is detected in the working field, playing back the first audio clip; in the video feed, detecting a current pose of the animal; calculating a deviation between the current pose of the animal and the target pose; in response to the deviation falling within a threshold: playing an audio clip of a secondary reinforcer; and dispensing a unit of a primary reinforcer via an integrated dispenser.

Abstract: A method for manufacturing microfibrillated cellulose, a particulate grinding medium suitable for use in said method, a material which wears rough, and a method for making said particulate grinding medium.

Abstract: A system may include a leadless cardiac pacing device including a body, a proximal hub, and a helical fixation member opposite the proximal hub; and a first elongate shaft having a lumen extending from a distal end of the elongate shaft proximally into the elongate shaft and a transverse member extending transversely across the lumen. The proximal hub may include a transverse channel extending into the proximal hub, the transverse channel being configured to engage the transverse member.

Abstract: Systems and methods are provided for delivering images to a patient before and/or during a medical procedure in which a patient is translated on a table relative to a gantry. In various example embodiments, images are projected to the patient while preserving the projected field size during table motion, thereby potentially reducing patient anxiety by providing a more immersive patient viewing experience. In some example embodiments, the projected field size is maintained by a display system that is secured to the table such that both a projector and a projection screen are fixed relative to the table, and relative to the patient, during translation of the table. In some example embodiments, a reduction in patient anxiety may be achieved by projecting images as virtual images that are perceived by the patient as residing at a depth that lies beyond the confined spatial region in which the patient resides.