Abstract: A lithotripsy device can comprise a handpiece, a lithotripsy probe extending from the handpiece, an energization source configured to deliver an energy to a distal end of the lithotripsy probe, a suction passage extending from the distal end of the probe and through the handpiece, and a capture device comprising a container comprising a storage space, an entry port configured to couple to the handpiece at the suction passage, and an exit port, and a capture element connected to the container and configured to facilitate capture of stone fragments within the storage space. A method can comprise fragmenting stones with a lithotripsy device, drawing a vacuum through the lithotripsy device to pull stone fragments and waste fluid therethrough, pulling the vacuum through a stone capture device connected to the lithotripsy device, depositing stone fragments within the stone capture device using a capture element, and drawing the vacuum through the device.

Abstract: Provided herein are methods of treating B7-H1-expressing tumors comprising administering an effective amount of MEDI4736 or an antigen-binding fragment thereof.

Abstract: A watercraft comprising a deck and a wall, the wall comprising a first reconfigurable panel, is provided. The deck has a front end, a back end, and a perimeter. The wall extends proximate a portion of the perimeter, thereby defining a use portion of the deck. The first reconfigurable panel is movable between a fixed first position and a fixed second position. When the first reconfigurable panel is in the second position, an area of the use portion of the deck is open.

Abstract: A seatbelt of a vehicle includes a buckle tilt mounting device for a tongue plate coupled with a seatbelt webbing restraining an occupant seated in a vehicle seat. The buckle tilt mounting device includes a buckle assembly having a buckle and a buckle cable, and further includes a pre-tensioner system having a housing, a driving member, and a pre-tensioner cable. When the pre-tensioner system is actuated at a time of a vehicle collision or at a time a vehicle collision is anticipated, the driving member retracts the pre-tensioner cable inside the housing such that the buckle assembly is rotatably moved and configured to reduce submarining load on the occupant.

Abstract: An applicator instrument for dispensing surgical fasteners includes a housing, and an elongated shaft extending from the housing. The elongated shaft has a proximal end secured to the housing, a distal end spaced from the proximal end, and a first axis extending between the proximal and distal ends of the elongated shaft. Surgical fasteners are disposed in the elongated shaft. The surgical fasteners are stacked at an angle relative to the first axis of the elongated shaft. A distal end cap having a surgical fastener dispensing window is secured to the distal end of the elongated shaft. The applicator instrument has a firing system disposed in the housing, and an actuator coupled with the firing system for activating the firing system to dispense the surgical fasteners through the surgical fastener dispensing window.

Abstract: Provided are compositions comprising compounds or precursors to compounds which may be used for a variety of therapeutic applications including, for example, treating and/or preventing a disease or disorder related to reduced or inadequate mitochondrial activity, including aging or stress, diabetes, obesity, and neurodegenerative diseases. The compounds relate generally to urolithins and precursors thereof, including but not limited to ellagitannins and urolithin A. In certain embodiments the compositions are presented in or as food products or nutritional supplements. These same compounds and compositions can also be used advantageously in generally healthy individuals to increase or maintain metabolic rate, decrease percent body fat, increase or maintain muscle mass, manage body weight, improve or maintain mental performance (including memory), improve or maintain muscle performance, improve or maintain mood, and manage stress.

Abstract: A coating composition comprises a urethane resin, a water absorbent polymer, and a curing agent. The urethane resin is obtained by reaction of an isocyanate reactive compound having multi-epoxide functionality and an isocyanate. When applied to a substrate and thermally cured, the coating composition forms a transparent and smooth coating having permanent anti-fog property.

Abstract: A computer implemented system is provided for improving performance of transmission in real-time or near real-time applications from at least one transmitter unit to at least one receiver unit. The system includes an intelligent data connection manager utility that generates or accesses performance data for two or more data connections associated with the two or more communication networks.

Abstract: A lithotripsy device can comprise a handpiece, a lithotripsy probe extending from the handpiece, an energization source configured to deliver an energy to a distal end of the lithotripsy probe, a suction passage extending from the distal end of the probe and through the handpiece, and a capture device comprising a container comprising a storage space, an entry port configured to couple to the handpiece at the suction passage, and an exit port, and a capture element connected to the container and configured to facilitate capture of stone fragments within the storage space. A method can comprise fragmenting stones with a lithotripsy device, drawing a vacuum through the lithotripsy device to pull stone fragments and waste fluid therethrough, pulling the vacuum through a stone capture device connected to the lithotripsy device, depositing stone fragments within the stone capture device using a capture element, and drawing the vacuum through the device.

Abstract: A dynamic control valve assembly for use in filling a liquid carbon dioxide storage and gas delivery system is provided, the assembly comprising: a valve body; an end nut with an inlet port for receiving liquid carbon dioxide; a chamber; an inlet cavity; a liquid port; a gas port; and a dynamic compound valve stem assembly for blocking the gas port while liquid carbon dioxide is delivered through the inlet port and allowing the liquid carbon dioxide to flow through the liquid port for storage in a liquid cylinder, and open the gas port and block the inlet port in order to allow carbon dioxide gasses from boiling liquid carbon dioxide within the liquid cylinder to pass through the gas port for storage in a gas cylinder until system pressure and temperature equilibrium is reached. The dynamic compound valve stem assembly comprises: a stem body having an inlet port poppet and a gas port poppet; an inlet cavity collar; and in some embodiments a collar biasing spring.

Abstract: An electroreductive and regenerative system includes an electrochemical reduction reactor having a housing and a reactor inlet. A cathode and an anode are disposed at least partially within a fluid flow-path. A spent ion-exchange resin slurry delivery inlet is fluidly connected to the reactor inlet. The spent ion-exchange resin slurry delivery inlet is connected to a source of spent ion-exchange slurry.

Abstract: An electrochemical reduction system includes an electrochemical reduction reactor. The electrochemical reduction reactor includes a housing having an internal fluid flow-path. A cathode having an outer, reducing, reactive surface is disposed within the internal fluid flow-path. An anode having an outer, oxidizing, reactive surface is also disposed within the internal fluid flow-path. At least portions of the cathode outer, reducing, reactive surface and the anode outer, oxidizing, reactive surface are separated by an electroactive gap.

Abstract: An interval control valve actuator includes an electrohydraulic pressure generator and an actuation pressure line extending between the generator and a valve. A hydraulic junction disposed in the actuation pressure line is selectively hydraulically joins the actuation pressure line to a backup pressure line. An interval control valve including a housing, a valve disposed in the housing, an electrohydraulic actuator hydraulically connected to the valve by an actuation pressure line. A hydraulic junction disposed between the electrohydraulic actuator and the valve and a backup pressure line hydraulically connected to the hydraulic junction, the backup pressure line being selectively hydraulically connectable to the actuation pressure line.

Abstract: An interval control valve actuator includes an electrohydraulic pressure generator and an actuation pressure line extending between the generator and a valve. A hydraulic junction disposed in the actuation pressure line is selectively hydraulically joins the actuation pressure line to a backup pressure line. An interval control valve including a housing, a valve disposed in the housing, an electrohydraulic actuator hydraulically connected to the valve by an actuation pressure line. A hydraulic junction disposed between the electrohydraulic actuator and the valve and a backup pressure line hydraulically connected to the hydraulic junction, the backup pressure line being selectively hydraulically connectable to the actuation pressure line.

Abstract: The disclosure relates to a method for pedestrian detection in a processor circuit of a motor vehicle, wherein an image data set describing an image of an environment of the motor vehicle is received from an environment sensor, and a machine learning model (ML model) is used to determine bounding boxes with potential images of pedestrians using the image data set, and from image data of the image data set the at least one ML model extracts feature data of image features and a detection of a completely or partially depicted pedestrian is carried out within a bounding box using the image features contained therein by way of a classifier of the at least one ML model, and the bounding box depicting the pedestrian is identified by a detection signal as the result of the detection.

Abstract: A dynamic control valve assembly for use in filling a liquid carbon dioxide storage and gas delivery system is provided, the assembly comprising: a valve body; an end nut with an inlet port for receiving liquid carbon dioxide; a chamber; an inlet cavity; a liquid port; a gas port; and a dynamic compound valve stem assembly for blocking the gas port while liquid carbon dioxide is delivered through the inlet port and allowing the liquid carbon dioxide to flow through the liquid port for storage in a liquid cylinder, and open the gas port and block the inlet port in order to allow carbon dioxide gasses from boiling liquid carbon dioxide within the liquid cylinder to pass through the gas port for storage in a gas cylinder until system pressure and temperature equilibrium is reached. The dynamic compound valve stem assembly comprises: a stem body having an inlet port poppet and a gas port poppet; an inlet cavity collar; and in some embodiments a collar biasing spring.

Abstract: An electrochemical contaminant remediation system includes a conditioning tank and a flow-through electrochemical reactor. The flow-through electrochemical reactor includes a housing having an internal liquid flow-path. A first electrode is disposed within the internal liquid flow path. A second electrode is spaced apart from the flow-through or solid first electrode, thereby creating an electroactive gap between the flow-through or solid first electrode and the second electrode.

Abstract: Compositions and methods are provided for determining platelet reactivity where the levels of Fc?RIIa on the surface of platelets is measured and if the levels of Fc?RIIa are greater than a reference value, the platelets have enhanced reactivity.