Abstract: Systems and methods for converting thresholds in plant breeding are provided. One example computer-implemented method includes accessing data indicative of hybrid plants at a first stage of a breeding pipeline, where the data includes values of parameter(s) of the hybrid plants; imposing a first threshold(s) included in a product definition for the breeding pipeline on the accessed data, whereby ones of the hybrid plants are considered at the first stage of the breeding pipeline based on satisfying the first threshold(s), and where the first threshold(s) is specific to one of the parameter(s); measuring the value(s) of the parameter(s) for the considered ones of the multiple hybrid plants; generating, based on an aggregate of the measured values of the parameter(s) for the considered ones of the multiple hybrid plants, a second threshold(s); and repeating the above for a second stage of the breeding pipeline with the second threshold(s).

Abstract: An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall.

Abstract: The present invention is generally directed to methods, systems and devices for communication of information related to emergency situations. In one aspect, the present invention provides a system for communication of information related to emergency situations. The system comprises a first printed circuit board, a second printed circuit board and a third printed circuit board. The first printed circuit board, the second printed circuit board and the third printed circuit board plug into each other to form a communication relay. The first printed circuit board is a communication platform comprising GPS, Cellular, a CO2 sensor, an Air Temp sensor and LoraWan. The second printed circuit board is a weather station comprising humidity and barometric pressure sensors. The third printed circuit board is a wind sensor comprising ultrasonic wind sensors.

Abstract: A method of kitting a robotic assembly for servicing aviation equipment including determining a current workscope associated with the equipment; determining at least one of parts and tooling associated with the current workscope; equipping the robotic assembly with at least some of the determined parts, tooling, or both; and the robotic assembly at least partially autonomously servicing the equipment using the equipped parts, tooling, or both.

Abstract: Apparatus and methods for distributing millimeter wave cellular service over a face of a building are disclosed. In certain embodiments, an antenna assembly includes an antenna upper unit configured to extend from a top of a building, such as from a roof. The antenna upper unit includes a first linear antenna array that radiates a transmit beam having a disc-shaped pattern. The antenna assembly includes an antenna lower unit configured to extend from the building beneath the antenna upper unit. The antenna lower unit includes a second linear antenna array that receives the transmit beam.

Abstract: A database system is described that includes components for storing time-series data and executing custom, user-defined computational expressions in substantially real-time such that the results can be provided to a user device for display in an interactive user interface. For example, the database system may process stored time-series data in response to requests from a user device. The request may include a start time, an end time, a period, and/or a computational expression. The database system may retrieve the time-series data identified by the computational expression and, for each period, perform the arithmetic operation(s) identified by the computational expression on data values corresponding to times within the start time and the end time. Once all new data values have been generated, the database system may transmit the new data values to the user device for display in the interactive user interface.

Abstract: A laundry appliance includes a cabinet, a tub positioned within the cabinet, and a basket supported for rotation within the tub. The laundry appliance includes a recirculating air flow system having a fan fluidly coupled to the tub and a vent tube with a first end fluidly coupled to a pressure side of the fan and a second end of the vent tube in fluid communication with an external atmosphere.

Abstract: A data-driven, unsupervised system (“owner inference module”) has been created that collects information from different data sources and infers ownership of an asset by discerning signals conveying ownership and using them to identify likely owners of assets. The owner inference module creates a graph of direct and indirect relationships among the asset and entities based on the collected information (i.e., the data and metadata). The owner inference module processes the graph and accounts for the varying strengths of different ownership signals based on any one or more of observations, expert knowledge, and preferences. The owner inference module quantifies the different signals of ownership of an entity and aggregates these values into an ownership likelihood score.

Abstract: Methods for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.

Abstract: The present invention relates to an anti-transglutaminase type 2 (TG2) antibody for use in the treatment of a scleroderma disease, such as localized or systemic scleroderma.

Abstract: A computer implemented method for servicing an engine including receiving information including an initial condition profile, CP1, of the engine; forming a workscope associated with a servicing operation of the engine in view of the initial condition profile, CP1; servicing the engine in view of the workscope; determining at least in part an updated condition profile, CP2, of the engine in view of information acquired during the service; and storing the updated condition profile, CP2, for use in a subsequent service operation.

Abstract: A diagnostic system for determining the presence of a target in a sample liquid that includes a diagnostic reader and a microfluidic strip having a microfluidic channel network therein. An actuator within the reader modifies the pressure of a gas in gaseous communication with a liquid-gas interface of a sample liquid within the microfluidic channel network to move and/or mix the sample liquid. The pressure modifications may be continuous and/or oscillatory.

Abstract: A system for remotely monitoring an appliance over a network includes an appliance having an appliance controller arranged to collect and send appliance data to a remote client device such as a mobile phone. The state data may include one or more parameters related to an aspect of the appliance, a timestamp, counter, or hash value. At the client device, the state data is compared with previously received state data, such as by comparing one of the parameters. If the state data parameter is different from a previously received parameter, the system concludes that the data is fresh and that the system is operating properly.

Abstract: Apparatus and methods are disclosed, including using a memory controller to partition a memory array into a first portion and a second portion, the first portion and second portion having non-overlapping logical block addressing (LBA) ranges. The memory controller assigns a first granularity of a first logical-to-physical (L2P) mapping table entry for the first portion of the memory array designated for a first usage, and a second granularity of a second L2P mapping table entry for the second portion of the memory array designated for a second usage, where the second granularity is not equal to the first granularity. The memory controller stores the first granularity and the second granularity in the memory array, and stores at least a portion of the first L2P mapping table entry and the second L2P mapping table entry in an L2P cache of the memory controller.

Abstract: A system, method, and computer-readable medium for performing a data center monitoring and management operation. The data center monitoring and management operation includes: generating a request for a client identifier or an access token for access to a target application programming interface (API); obtaining an access policy associated with the target API; determining a least privileged API access permission based upon the access policy associated with the target API; and, using the client identifier or access token to access the target API when the least privileged API access permission allows access to the target API.

Abstract: A combination washer/dryer laundry appliance is provided, including a cabinet, a tub, a laundry basket forming a chamber for washing/drying laundry articles, a drying system and a blower configured to generate a flow of fluid through a flowpath including the chamber and the drying system, and a controller. The controller is configured to execute operations that include performing, at the laundry basket, a spin cycle, and operating the blower to inhibit the flow of fluid through a rear wall perforation at the laundry basket and a plenum between the laundry basket and the tub during the spin cycle.

Abstract: A combination washer/dryer laundry appliance is provided, including a cabinet defining an interior volume, a tub mounted within the interior volume of the cabinet, a laundry basket rotatably mounted within the tub, the laundry basket defining a chamber for the receipt of laundry articles, and a dryer system coupled to the tub. The dryer system is in fluid communication with the chamber and configured to receive a flow of fluid from the chamber and remove moisture from the flow of fluid and provide dried air to the chamber. The laundry appliance configured to perform, at the laundry basket, a spin cycle, and operate the dryer system prior to completion of performing the spin cycle.

Abstract: A turbine engine component assembly includes a first part comprising a ceramic matrix composite material and having a first flange defining a first borehole, a second part defining a second borehole, and a pin inserted, in an axial direction, through the first borehole and the second borehole to connect the first part to the second part. The pin includes a first contact portion positioned at a first axial location of the pin corresponding to the first borehole and an elongated portion extending axially from the first contact portion. The first contact portion includes a first chamfered section, a second chamfered section, and a first contact surface between the first chamfered section and the second chamfered section. The first chamfered section and the second chamfered section slope away from the first contact surface with decreasing diameters.

Abstract: Provided herein are methods that enable parallel evaluation of multiple functional nucleic acids in individual cells or subpopulations of cells, in the context of incubation with other types of single cells. The key insight is concurrent measurement of polynucleic acids derived from small populations of at least two different cell types, such that function in one cell type is linked to the clonal identity of another cell. These methods simultaneously process thousands, millions, or more single cells or small populations of cells. The method integrates molecular, algorithmic, and engineering approaches. This invention has broad and useful application in a number of biological and medical fields, including immunology and drug discovery.

Abstract: Disclosed herein are compositions and methods for making polycrystalline thin films having very large grains sizes and exhibiting improved properties over existing thin films.