Abstract: This application relates to compounds of Formula (I): or pharmaceutically acceptable salts thereof, which are inhibitors of PI3K-? which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.

Abstract: The present disclosure describes methods of treating an injury in a subject using placental tissue streamers, engineered tissue placental tissue hybrids, suture placental tissue hybrids, placental tissue patch hybrids, and tissue hybrids, and the use of these compositions to repair, treat, or support an injury or degenerative process in a subject.

Abstract: A method of forming an AFX zeolite in a hydrothermal synthesis that exhibits a silica to alumina (SiO2AI2O3) molar ratio (SAR) that is between 8:1 and 26:1; has a morphology that includes one or more of cubic, spheroidal, or rhombic particles with a crystal size that is in the range of about 0.1 micrometer (?m) to 10 ?m. This AFX zeolite also exhibits a Brönsted acidity that is in the range of 1.2 mmol/g to 3.6 mmol/g as measured by ammonia temperature programmed desorption. A catalyst formed by substituting a metal into the framework of the zeolite exhibits about a 100% conversion of NO emissions over the temperature range of 300° C. to 650° C.

Abstract: A separator for use in an electrochemical cell, such as a lithium-ion secondary battery, that includes a plurality of first inorganic particles, one or more second inorganic particles, a polymeric binder, wherein the weight ratio of the first inorganic particles to the second inorganic particles is in the range from 1:99 to 99:1 and the weight ratio of the combined first and second inorganic particles to the polymeric binder is in the range from 50:50 to 99:1. The inorganic particles being a type of Li-exchanged zeolite having a lithium (Li) concentration in the range of 0.1 wt. % to 20 wt. % and a sodium (Na) concentration that is lower than 5 wt. %, based on the overall weight of the Li-exchanged zeolite. The second inorganic particles being different in composition than the first inorganic particles and having a sodium (Na) concentration in the range of 0.005 wt. % to 1.0 wt. %.

Abstract: A method of forming an SSZ-13 zeolite in a hydrothermal synthesis yields an SSZ-13 zeolite that exhibits a silica to alumina (SiO2:Al2O3) molar ratio (SAR) that is less than 16:1; has a morphology that includes one or more of cubic, spheroidal, or rhombic particles with a crystal size that is in the range of about 0.1 micrometer (?m) to 10 ?m. This SSZ-13 also exhibits a Brönsted acidity that is in the range of 2.0 mmol/g to 3.4 mmol/g as measured by ammonia temperature programmed desorption. A catalyst formed by substituting a metal into the framework of the zeolite provides for low temperature light-off of the NOx conversion reactions, while maintaining substantial performance at higher temperatures demonstrating hydrothermal stability.

Abstract: An apparatus, system and method for securing wheeled shipping carts within a shipping container. The apparatus, system and method for securing wheeled shipping carts within a shipping container secures the shipping racks across the width of the container and vertically, and then end-to-end inside the length of the container from the fixed end of the container to the doors as the container is loaded. In addition, the system and method secures wheeled shipping carts within a shipping container using a securing apparatus installed within the shipping container to constrain the wheeled shipping carts both vertically and horizontally in location during transport.

Abstract: A method of making an oxygen storage material (OSM) with developed mesoporosity having a small fraction of pores <10 nm (fresh or aged), and resistance to thermal sintering is provided. This OSM is suitable for use as a catalyst and catalyst support. The method of making this oxygen storage material (OSM) includes the preparation of a solution containing pre-polymerized zirconium oligomers, cerium, rare earth and transition metal salts; the interaction of this solution with a complexing agent that has an affinity towards zirconium; the formation of a zirconium-based precursor; and the co-precipitation of all constituent metal hydroxide with abase.

Abstract: An apparatus, system and method for securing wheeled shipping carts within a shipping container. The apparatus, system and method for securing wheeled shipping carts within a shipping container secures the shipping racks across the width of the container and vertically, and then end-to-end inside the length of the container from the fixed end of the container to the doors as the container is loaded. In addition, the system and method secures wheeled shipping carts within a shipping container using a securing apparatus installed within the shipping container to constrain the wheeled shipping carts both vertically and horizontally in location during transport.

Abstract: A cerium-zirconium oxide-based ionic conductor (CZOIC) material including zirconium oxide in an amount ranging from 5 wt. % up to 95 wt. %, cerium oxide in an amount ranging from 95 wt. % to 5 wt. %, and at least one oxide or a rare earth metal in an amount ranging from 30 wt. % or less, based on the overall mass of the CZOIC material. The CZOIC material exhibits a structure comprising one or more expanded unit cells and a plurality of crystallites having ordered nano-domains. The structure of the CZOIC material exhibits a crystal lattice defined by a d-value measured at multiple (hkl) locations using a SAED technique that exhibit distortions, such that the d-values for the same (hkl) location varies from about 2% to about 5% from the d-value measured for a reference cerium-zirconium material at the same (hkl) location.

Abstract: An electrochemical cell, such as a secondary cell of a lithium-ion battery, that includes a positive electrode with an active material that acts as a cathode; a negative electrode with an active material that acts as an anode; a non-aqueous electrolyte; and a separator placed between the positive electrode and negative electrode. The separator including an inorganic material. This inorganic material includes a mixture of a first inorganic particle and one or more second inorganic particles; wherein the inorganic material absorbs one or more of moisture, free transition metal ions, or hydrogen fluoride (HF) that become present in the electrochemical cell. One or more of the cells may be combined in a housing to form a lithium-ion secondary battery.

Abstract: An apparatus, system and method for securing wheeled shipping carts within a shipping container. The apparatus, system and method for securing wheeled shipping carts within a shipping container secures the shipping racks across the width of the container and vertically, and then end-to-end inside the length of the container from the fixed end of the container to the doors as the container is loaded. In addition, the system and method secures wheeled shipping carts within a shipping container using a securing apparatus installed within the shipping container to constrain the wheeled shipping carts both vertically and horizontally in location during transport.

Abstract: A cell for use in an electrochemical cell, such as a lithium-ion secondary battery that includes a positive electrode with an active material that acts as a cathode and a current collector; a negative electrode with an active material that acts as an anode and a current collector; a non-aqueous electrolyte; and a separator placed between the positive and negative electrodes. At least one of the cathode, the anode, the electrolyte, and the separator includes an inorganic additive in the form of a metal aluminate or a mixture of metal aluminates that absorbs one or more of moisture, free transition metal ions, or hydrogen fluoride (HF) that become present in the cell. One or more of the cells may be combined in a housing to form a lithium-ion secondary battery. The inorganic additive may also be incorporated as a coating applied to the internal wall of the housing.

Abstract: A cell for use in an electrochemical cell, such as a lithium-ion secondary battery that includes a positive electrode with an active material that acts as a cathode and a current collector; a negative electrode with an active material that acts as an anode and a current collector; a non-aqueous electrolyte; and a separator placed between the positive and negative electrodes. At least one of the cathode, the anode, the electrolyte, and the separator includes an inorganic additive in the form of a transition phase alumina or a type of boehmite that absorbs one or more of moisture and/or hydrogen fluoride (HF) that become present in the cell. One or more cells may be combined in a housing to form a lithium-ion secondary battery. The inorganic additive may also be incorporated as a coating applied to the internal wall of the housing.

Abstract: An apparatus, system, and method for removing impurities from a non-aqueous electrolyte used in an electrochemical cell. The apparatus includes a vessel having one or more chambers with an inlet and an outlet configured to allow the flow of the electrolyte through the one or more chambers; and an inorganic scavenging agent located within the one or more chambers. The inorganic scavenging agent includes one or more types of zeolite particles, at least one type of absorbent filler particles, or a combination of the zeolite and absorbent filler particles. The inorganic scavenging agent absorbs one or more of moisture, free transition metal ions, or hydrogen fluoride (HF) that is present as impurities in the non-aqueous electrolyte.

Abstract: An electrochemical cell that includes a positive electrode with an active material acting as a cathode; a negative electrode with an active material acting as an anode; a non-aqueous electrolyte; and a separator placed between the positive electrode and negative electrode. In one embodiment, the separator includes an inorganic material, i.e., a type of boehmite, formed of nanometer-sized particles and optionally one or more binders and/or ceramic particles. In a second embodiment, at least one of the cathode, the anode, the electrolyte, and the separator includes the boehmite particles, which absorb one or more of moisture and/or hydrogen fluoride that become present in the cell. One or more of the cells may be combined in a housing to form a lithium-ion secondary battery.

Abstract: A cell for use in an electrochemical cell, e.g., a lithium-ion secondary battery, that includes a positive electrode with an active material acting as a cathode and a current collector; a negative electrode with an active material acting as an anode and a current collector; a non-aqueous electrolyte; and a separator placed between the electrodes. At least one of the cathode and anode includes an inorganic additive in the form of a zeolite having a Si:Al ratio ranging from 2-50 that absorbs one or more of moisture, free transition metal ions, or hydrogen fluoride that become present in the cell. Multiple cells may be combined in a housing to form a lithium-ion secondary battery. The inorganic additive may be incorporated as part of the positive electrode, the negative electrode, or a combination thereof.

Abstract: A method of continuously forming AEI-type zeolites in a tubular reactor via a hydrothermal synthesis. A gel composition formed upon using this method includes one or more sources of silica, alumina, organic structure directing agents (OSDA), alkali metal ions; water; and optionally zeolite seeds. This gel composition is defined by the molar ratios of SiO2/AI2O3 15:1 to 100:1; M2O/SiO2 0.15:1 to 0.30:1; ROH/SiO2 0.05:1 to 0.2:1; and H2O/SiO2 5:1 to 20:1; wherein M is the alkali metal ion and R is an organic moiety derived from the OSDA. This gel composition, after reacting at a temperature between 180° C. to about 220° C. for less than 2 hours forms the crystalline AEI-type zeolite having a silica to alumina ratio (SiO2/AI2O3) that is greater than 14:1.

Abstract: A nanocrystal-sized cerium-zirconium-aluminum mixed oxide material includes at least 20% by mass zirconium oxide; between 5% to 55% by mass cerium oxide; between 5% to 60% by mass aluminum oxide; and a total of 25% or less by mass of at least one oxide of a rare earth metal selected from the group of lanthanum, neodymium, praseodymium, or yttrium. The nanocrystal-sized cerium-zirconium-aluminum mixed oxide exhibits hierarchically ordered aggregates having a dso particle size less than 1.5 ?m, and retains at least 80% of surface area and pore volume after ageing at temperature higher than 1000° C. for at least 6 hours. The nanocrystal-sized cerium-zirconium-aluminum mixed oxide material is prepared using a co-precipitation method followed by milling the dried and calcined oxide material.

Abstract: An oxygen storage material (OSM) that exhibits enhanced redox properties, developed mesoporosity, and a resistance to sintering. The oxygen storage material (OSM) has a high oxygen storage capacity (i.e., OSC>1.5 mmol H2/g) and enhanced reducibility (i.e., bimodal TPR-H2 profile with two Tmax in the temperature range from 150° C. to 550° C.). The OSM is suitable for use as a catalyst and a catalyst support. The method of making the oxygen storage material comprises the preparation of a solution containing zirconium, cerium, rare earth and transition metal salts, followed by the co-precipitation of all constituent metal hydroxides with a base.

Abstract: A method of forming AEI-type zeolites in a hydrothermal synthesis without the use of hydrogen fluoride (HF) and in the presence of an FAU zeolite NaY with SAR ?5, a Y zeolite with a SAR ?5, or a combination thereof. A gel composition formed upon using this method includes one or more sources of silica, alumina, organic structure directing agents (OSDA), and alkali metal ions; zeolite seeds; and water. This gel composition is defined by the molar ratios of: SiO2/AI2O3 18:1 to 100:1; M2O/SiO2 0.15:1 to 0.30:1; ROH/SiO2 0.05:1 to 0.13:1; and H2O/SiO2 5:1 to 20:1; wherein M is the alkali metal ion and R is an organic moiety derived from the OSDA. This gel composition, after reacting at a temperature between 135° C. to about 200° C. for 10 hours to 168 hours forms the crystalline AEI-type zeolite having a silica to alumina ratio (SiO2:AI2O3) that is greater than 15:1.