Abstract: Gaseous carbon compounds can be converted to carbon neutral or negative products using biological processes to metabolise the gaseous carbon compounds or use thermochemical processes to convert gaseous carbon compounds to syngas followed by thermochemical or biological processes to produce products. The gaseous carbon compounds include a mixture of CO2 and CH4 from either a single source, or two or more different sources. Separate biological processes are incorporated to process different gaseous carbon compounds. A gaseous carbon compound produced as a by-product of one biological process can be used as at least part of the feedstock for another process. A renewable energy system can be provided to power equipment. A control system can be used to control flow of gaseous carbon compounds and reactants entering the entire carbon processing systems to provide mass balanced quantities of gaseous carbon compounds and reactants in each processing system and/or between processing systems.

Abstract: Disclosed is a latching mechanism for a high-torque tool that allows a top semicircular segment to be connected and disconnected from a bottom semicircular segment, which allows a hex jaw (reaction gear) to engage a fluid fitting static nut for application of high torques. A pivoted latch has a curved blade, which is mounted closer to the center point of the hex jaw (reaction gear) than the latch pivot pin of the pivoted latch so that all of the forces are absorbed by the curved blade rather than the latch pivot pin.

Abstract: A pressure cylinder includes a working cylinder and an intensification cylinder that is divided by a separator block. A working piston is arranged in the working cylinder and connected to a working rod that extends to an end portion. An intensification piston and an intensification rod are arranged in the intensification cylinder. A pump is configured to provide a pressurized hydraulic fluid to the pressure cylinder. A fluid reservoir is configured to supply a hydraulic fluid to the pump. A first valve is configured to selectively regulate hydraulic fluid flow between the pressure cylinder and the fluid reservoir and the pump. A second valve is configured to selectively regulate fluid flow between a first valve and the advance intensification chamber. A controller is in communication with the first valve and the second valve. The controller is configured to coordinate movement of the working piston and the intensification piston.

Abstract: Disclosed are cartridge components, cartridges, systems, and methods for isolating analytes from biological samples. In various aspects, the cartridge components, cartridges, systems, and methods may allow for a rapid procedure that requires a minimal amount of material from complex fluids.

Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.

Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.

Abstract: Disclosed herein are pharmaceutical compositions for the treatment of cancer. In particular, disclosed herein are methods and uses of the pharmaceutical compositions for treating, preventing and/or managing cancers of the brain and/or central nervous system. The pharmaceutical compositions may comprise: (i) 5-FU, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable analogue thereof; (ii) folinic acid, or a pharmaceutically acceptable salt thereof; and (iii) a cyclodextrin or a pharmaceutically acceptable salt thereof.

Abstract: A fuel supply circuit of an aircraft engine includes a centrifugal pump mechanically coupled with an engine shaft delivering mechanical power. The circuit further includes at least one electromagnetic pump including at least one stator delimiting an annular internal volume in which is present a rotor able to drive a fluid, a plurality of magnets annularly distributed on the rotor and at least a plurality of coils annularly distributed inside the stator face-to-face with the magnets. The rotor is connected to the engine shaft by a one-way clutching element.

Abstract: Disclosed herein are methods for the growth of (110) GaAs solar cells by hydride vapor phase epitaxy (HVPE) as an advance towards a (110)-oriented device platform with substrate reuse via spalling. Controlled spalling offers a fracture-based path to substrate amortization, allowing device removal and substrate reuse, but the faceted surface generated in spalling of (100)-GaAs presents hurdles to direct regrowth of subsequent devices. Spalling of (110)-oriented substrates takes advantage of the natural (110) cleavage plane in zinc-blende III-V materials, eliminating this faceting.

Abstract: Methods and systems for control of solid phase peptide synthesis are generally described. Control of solid phase peptide synthesis involves the use of feedback from one or more reactions and/or processes (e.g., reagent removal) taking place in the solid phase peptide synthesis system. In some embodiments, a detector may detect one or more fluids flowing across a detection zone of a solid phase peptide synthesis system and one or more signals may be generated corresponding to the fluid(s). For instance, an electromagnetic radiation detector positioned downstream of a reactor may detect a fluid exiting the reactor after a deprotection reactor and produce a signal(s). In some embodiments, based at least in part on information derived from the signal(s), a parameter of the system may be modulated prior to and/or during one or more subsequent reactions and/or processes taking place in the solid phase peptide synthesis system.

Abstract: A solidified melt extrudate comprising an active pharmaceutical ingredient in an amorphous form and a combination of at least two polymers.

Abstract: A fuel supply circuit of an aircraft engine includes a centrifugal pump mechanically coupled with an engine shaft delivering mechanical power. The circuit further includes at least one electromagnetic pump including at least one stator delimiting an annular internal volume in which is present a rotor able to drive a fluid, a plurality of magnets annularly distributed on the rotor and at least a plurality of coils annularly distributed inside the stator face-to-face with the magnets. The rotor is connected to the engine shaft by a one-way clutching element.

Abstract: Devices, systems and methods for encoding information using optical components are described. An example photonic filtered sampler includes a spectral shaper configured to receive an optical pulse train, a dispersive element positioned to receive an output of the spectral shaper and to expand spectral contents thereof in time, and a modulator configured to receive an output of the dispersive element and a radio frequency (RF) signal, and to produce a modulated output optical signal in accordance with the RF signal. In this configuration, one or more characteristics of the modulated output optical signal is determined based on a spectral shape provided by the spectral shaper and dispersive properties of the dispersive element.

Abstract: Methods, devices and systems for providing accurate measurements of timing errors using optical techniques are described. An example timing measurement device includes an optical hybrid that receives two optical pulse trains and produces two or more phase shifted optical outputs. The timing measurement device further includes two or more optical filters that receive the outputs of the optical hybrid to produce multiple pulse signals with distinctive frequency bands. The device also includes one or more photodetectors and analog-to-digital converters to receive to produce electrical signals in the digital domain corresponding to the optical outputs of the hybrid. A timing error associated with the optical pulse trains can be determined using the electrical signals in digital domain based on a computed phase difference between a first frequency band signal and a second frequency band signal and a computed frequency difference between the first frequency band signal and the second frequency band.

Abstract: Devices, systems and methods for encoding information using optical components are described. An example photonic filtered sampler includes a spectral shaper configured to receive an optical pulse train, a dispersive element positioned to receive an output of the spectral shaper and to expand spectral contents thereof in time, and a modulator configured to receive an output of the dispersive element and a radio frequency (RF) signal, and to produce a modulated output optical signal in accordance with the RF signal. In this configuration, one or more characteristics of the modulated output optical signal is determined based on a spectral shape provided by the spectral shaper and dispersive properties of the dispersive element.

Abstract: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as cancers and viral infections.

Abstract: A turbomachine including a rotary body including a motor shaft supplying mechanical power, and at least one magnetic drive pump including at least: one stator delimiting an annular inner space and including a first and a second flange, a rotor arranged in the inner space between the first and second flanges and capable of driving fluid, the rotor being able to rotate about an axis of rotation, a pair of magnets having opposite polarities coaxially arranged on the rotor with the axis of rotation, a magnet arranged on the first flange in order to co-operate with one of the magnets of the pair of magnets of the rotor, a magnetic rotator for rotating the rotor arranged on the second flange, the second flange being non-magnetic.

Abstract: A solidified melt extrudate comprising an active pharmaceutical ingredient in an amorphous form and a combination of at least two polymers.

Abstract: Wheel arch for a motor vehicle with a wheel arch housing component for at least partially delimiting the wheel arch for a vehicle wheel of the motor vehicle, and with a wheel arch lining which is arranged on the surface of the wheel arch housing component facing the wheel and extends at least partially along this surface, the wheel arch lining having at least one support layer and one fiber layer, wherein the support layer forms the outer side of the wheel arch lining facing the wheel and the fiber layer is arranged between the wheel arch housing component and the support layer and the support layer and the fiber layer are thermally bonded to one another and formed into a wheel arch lining and wherein at least 50%, preferably at least 65%, preferably at least 80% of the surface of the fiber layer is in contact with the wheel arch housing component.