Abstract: A method to provide skin care treatment is provided. The method includes receiving, by an electrical stimulator apparatus, programmable instructions from an external device for a skin care treatment. The electrical stimulator apparatus delivers an electric current to an area of skin through a plurality of electrodes. The electric current is controlled based on the skin care treatment. The external device presents guidance corresponding with the skin care treatment. The guidance is configured to aid a user in operating the electrical stimulator apparatus.

Abstract: A solidified melt extrudate comprising an active pharmaceutical ingredient in an amorphous form and a combination of at least two polymers.

Abstract: A vascular prosthesis may be implanted in a vessel, having substantially a T-shape, that includes a proximal tubular part forming the base of the “T” and a distal tubular part forming the head of the “T”. The second end portion of the distal tubular part is formed by a flap. The flap is opposed to a circumferential indentation in the deployed position. The structural frame of the flap includes an arched segment connected at its ends to the intermediate portion of the distal tubular part. The arched segment is bendable so as to form a joint for the folding/unfolding movement of the flap.

Abstract: A bundle of roofing shingles, including at least four rows of roofing shingles, where the at least four rows of roofing shingles includes a first roofing shingle row, a second roofing shingle row, a third roofing shingle row, and a fourth roofing shingle row, where the first roofing shingle row includes a first roofing shingle having a first length; and where the second roofing shingle row includes: a second roofing shingle having a second length, and a third roofing shingle having a third length, where the second roofing shingle is adjacent the third roofing shingle, where the second length is greater than the third length, and where the second row is located above the first row.

Abstract: Aspects of the subject disclosure may include, for example, determining that one or more tests are to be executed for a core network of a telecommunications system, based on the determining, transmitting one or more test initiation commands to a set of user equipment (UEs) of a plurality of UEs communicatively coupled to the core network, wherein the one or more test initiation commands cause the set of UEs to execute the one or more tests, obtaining, from the set of UEs, results associated with the one or more tests, analyzing the results based on one or more machine learning (ML) models to identify a network issue, and responsive to the analyzing, performing one or more actions to address the network issue. Other embodiments are disclosed.

Abstract: Wheel arch for a motor vehicle with a wheel arch housing component for at least partially delimiting the wheel arch for a vehicle wheel of the motor vehicle, and with a wheel arch lining which is arranged on the surface of the wheel arch housing component facing the wheel and extends at least partially along this surface, the wheel arch lining having at least one support layer and one fiber layer, wherein the support layer forms the outer side of the wheel arch lining facing the wheel and the fiber layer is arranged between the wheel arch housing component and the support layer and the support layer and the fiber layer are thermally bonded to one another and formed into a wheel arch lining and wherein at least 50%, preferably at least 65%, preferably at least 80% of the surface of the fiber layer is in contact with the wheel arch housing component.

Abstract: Described herein are devices and methods related to compositionally graded buffers (CGB) and methods and/or systems for producing CGBs. CGBs enable the growth of high quality materials that are lattice mismatched to a substrate. More specifically, the present disclosure relates to methods for making CGBs by hydride vapor phase epitaxy (HVPE). HVPE methods using a single chamber for producing a CGB may result in a transience in the CGB layers as the flows supplying the reactants are switched to produce the next subsequent layer in the CGB. In contrast to this static style of grading, the present disclosure describes a dynamic method for producing CGBs, in which multiple growth chambers are utilized.

Abstract: Devices, methods for analog-to-digital converters (ADCs) that perform high-dynamic range measurements based on optical techniques are disclosed. In one example aspect, an optical encoder includes a polarization rotator configured to receive a train of optical pulses, and an electro-optic (EO) modulator coupled to an output of the polarization rotator. The EO modulator is configured to receive a radio frequency (RF) signal and to produce a phase modulated signal in accordance with the RF signal. The optical encoder also includes a polarizing beam splitter coupled to the output of the EO modulator; and an optical hybrid configured to receive two optical signals from the polarizing beam splitter and to produce four optical outputs that are each phase shifted with respect to one another.

Abstract: The present invention relates to adjustable flow control valves, for example to an Adjustable Pressure Limiting (APL) valve. The adjustable valve (2) described comprises a valve body (4) comprising a valve seat (6), a valve member (10) movable relative to the valve seat (6), a first valve cap (20), a second valve cap (50) and a biasing element (30) to bias the valve member (10) away from the first valve cap (20). The first valve cap (20) is movable to increase the biasing force applied by the biasing element (30). The second valve cap (50) is engageable with the first valve cap (20) to prevent such movement of the first valve cap (20) beyond a selected position, but to allow movement of the first valve cap (20) in an opposite direction, way from said position.

Abstract: Face masks, including filter masks, having improved stability, including face masks having a sealing member (25) depending from the mask body for engagement with the wearer's face, the mask body comprising a nasal portion (27) for accommodating the nose of the wearer, a mouth portion (26) for accommodating the mouth of the wearer, and cheek portions (28) extending laterally across the wearer's cheeks.

Abstract: Face masks, including filter masks, and methods for their production. The disclosed masks include a face mask comprising a mask body that defines a cavity for accommodating the nose and mouth of a wearer and a sealing member depending from the mask body for engagement with the wearer's face, the mask body comprising a filter (91) and a gas inlet (142), the filter being located in a first region of the mask body and the gas inlet being located in a second region of the mask body; and a nasal portion for accommodating the nose of the wearer, a mouth portion for accommodating the mouth of the wearer, and cheek portions (134, 135) extending laterally across the wearer's cheeks.

Abstract: The disclosed methods of manufacturing filter masks include using an overmoulding step to both form a sealing member and to fix the sealing member to a support frame and a sheet of filtering material.

Abstract: Face masks, including filter masks, and methods for their production. The disclosed methods include using an overmoulding step to both form a sealing member and to fix the sealing member to a support frame and a sheet of filtering material.

Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.

Abstract: Gaseous carbon compounds can be converted to carbon neutral or negative products using biological processes to metabolise the gaseous carbon compounds or use thermochemical processes to convert gaseous carbon compounds to syngas followed by thermochemical or biological processes to produce products. The gaseous carbon compounds include a mixture of CO2 and CH4 from either a single source, or two or more different sources. Separate biological processes are incorporated to process different gaseous carbon compounds. A gaseous carbon compound produced as a by-product of one biological process can be used as at least part of the feedstock for another process. A renewable energy system can be provided to power equipment. A control system can be used to control flow of gaseous carbon compounds and reactants entering the entire carbon processing systems to provide mass balanced quantities of gaseous carbon compounds and reactants in each processing system and/or between processing systems.

Abstract: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as cancers and viral infections.

Abstract: Methods and systems for control of solid phase peptide synthesis are generally described. Control of solid phase peptide synthesis involves the use of feedback from one or more reactions and/or processes (e.g., reagent removal) taking place in the solid phase peptide synthesis system. In some embodiments, a detector may detect one or more fluids flowing across a detection zone of a solid phase peptide synthesis system and one or more signals may be generated corresponding to the fluid(s). For instance, an electromagnetic radiation detector positioned downstream of a reactor may detect a fluid exiting the reactor after a deprotection reactor and produce a signal(s). In some embodiments, based at least in part on information derived from the signal(s), a parameter of the system may be modulated prior to and/or during one or more subsequent reactions and/or processes taking place in the solid phase peptide synthesis system.

Abstract: Disclosed is a respiratory interface device (1) and components thereof. The respiratory interface device (1) comprises a body (2), a frame (3), and an inlet conduit (4). The frame has a front wall (10a), side walls (10b), and side arms (12), and a support platform (11) extending rearwardly from the front wall (10a). An inlet opening (13) is defined in the support platform (11). The body (2) forms a chamber with the support platform (11) and comprises at least one nasal outlet (5), a base opening (7), and at least one further opening (6), through which the support platform (11) extends. The inlet conduit (4) comprises a connector (18) that clamps the body (2) and the support platform (11) together.

Abstract: Disclosed are cartridge components, cartridges, systems, and methods for isolating analytes from biological samples. In various aspects, the cartridge components, cartridges, systems, and methods may allow for a rapid procedure that requires a minimal amount of material from complex fluids.

Abstract: Methods and system for solid phase peptide synthesis are provided. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. New amino acid residues are added via a coupling reaction between an activated amino acid and an amino acid residue of the immobilized peptide. Amino acids may be activated using, e.g., a base and an activating agent. Certain inventive concepts, described herein, relate to methods and systems for the activation of amino acids. These systems and methods may allow for fewer side reactions and a higher yield compared to conventional activation techniques as well as the customization of the coupling reaction on a residue-by-residue basis without the need for costly and/or complex processes.