Abstract: The present invention relates to genes and materials for improving plant health, preferably against phytopathogenic microorganisms, and/or against coumarin-induced adverse effects on plant health. Furthermore, the invention pertains to methods and uses of such genes and mate-rials for creating correspondingly beneficial plant cells, plant parts and whole plants, and also relates to products obtained from such plants or plant parts.

Abstract: A system for including a chatbot into a group chat session is provided. The system receives a chatbot mention message from a user in the group chat session. The chatbot mention message includes a chatbot prompt for a chatbot. The system generates a prompt using the chatbot mention message and communicates the response as a chatbot response message to each user in the group chat session.

Abstract: An aerosol provision device for generating aerosol for user inhalation can include a first aerosol generating area and a second aerosol generating area each for receiving an aerosol precursor material; a mouthpiece from which a user inhales generated aerosol during use, wherein the mouthpiece comprises first and second mouthpiece openings; a first pathway extending from the first aerosol generating area to the first mouthpiece opening for transporting a first aerosol generated from the aerosol precursor material in the first aerosol generating area; and a second pathway extending from the second aerosol generating area chamber to the second mouthpiece opening for transporting a second aerosol generated from the aerosol precursor material in the second aerosol generating area, wherein the first and second pathways are physically isolated from one another to prevent mixing of the first and second aerosols as the first and second aerosols are transported along the respective pathways.

Abstract: An aerosol delivery device including a power supply; a vaporizer arranged to selectively receive power from the power supply to generate an aerosol from an aerosol precursor material for user inhalation; and a first electrical interface arranged to provide an electrical connection between the aerosol delivery device and a second aerosol delivery device so as to at least one of: supply power to or receive power from the second aerosol delivery device, or supply control signals to or receive control signals from the second aerosol delivery device.

Abstract: The present invention is directed to a modified clostridial neurotoxin comprising a botulinum neurotoxin A (BoNT/A) Hcc domain, wherein the Hcc domain comprises a modification of methionine 1144 (MI 144), and wherein the modification increases oxidative resistance of the modified clostridial neurotoxin when compared to an otherwise identical clostridial neurotoxin lacking the modification. Also provided are (inter alia) corresponding methods for producing the same, methods for selecting oxidation resistant clostridial neurotoxins, nucleic acids encoding the same, and therapeutic uses of said modified clostridial neurotoxins.

Abstract: The technology relates in part to binding molecules that specifically bind to a polypeptide that is the Isoform 2 of mesotheiin, or that specifically bind to an antigenic determinant (epitope) of the isoform 2 of mesotheiin, or that specifically bind to polypeptides containing an antigenic determinant (epitope) of the isoform 2 of mesotheiin, chimeric PD1 receptors that bind to PD ligands such as PDLs, to polynucleotides including vectors that encode such binding molecules, to ceils presenting such binding molecules and to methods of making such cells, to humanized forms of the binding molecules, and to methods of using such binding molecules, such as for treating cancers (e.g., ovarian cancers and mesotheliomas), including cancers in which the Isoform 2 of mesotheiin is specifically expressed and/or upregulated relative to normal tissues.

Abstract: The technology relates in part to binding molecules that specifically bind to a polypeptide that is the Isoform 2 of mesothelin, or that specifically bind to an antigenic determinant (epitope) of the isoform 2 of mesothelin, or that specifically bind to polypeptides containing an antigenic determinant (epitope) of the isoform 2 of mesothelin, chimeric PD1 receptors that bind to PD ligands such as PDLs, to polynucleotides including vectors that encode such binding molecules, to ceils presenting such binding molecules and to methods of making such cells, to humanized forms of the binding molecules, and to methods of using such binding molecules, such as for treating cancers (e.g., ovarian cancers and mesotheliomas), including cancers in which the Isoform 2 of mesothelin is specifically expressed and/or upregulated relative to normal tissues.

Abstract: A medical connector can include a threaded connection fitting configured to couple to a medical implement by rotation of the medical implement in a tightening direction relative to the threaded connection fitting. The threaded connection fitting can include one or more first engagement features. The connector can have a fluid pathway for transferring fluid through the device and a rotation mechanism. The rotation mechanism permits the threaded connection fitting to rotate in a loosening direction relative to the housing, such as to impede unintended disconnection of the medical implement from the threaded connection fitting. In some cases, the connector can have a disengaged configuration that permits the threaded connection fitting to rotate relative to the housing in the tightening direction and in the loosening direction.

Abstract: In some embodiments, an apparatus can include a robotic arm cart for transporting, delivering, and securing robotic arms to a surgical table having a table top. The arm cart can include an arm container and a base. The arm container can be configured to receive and contain one or more robotic arms. The arm cart can include a first coupling member configured to engage with a second coupling member associated with a surgical table such that, when the first coupling member is engaged with the second coupling member, the one or more robotic arms can be releasably coupled with the surgical table. The arm cart can provide for movement of the one or more robotic arms in at least one of a lateral, longitudinal, or vertical direction relative to the table top prior to the securement of the one or more robotic arms to the surgical table.

Abstract: A chatbot system for filtering conversation content. A chatbot system receives, from a client system, a prompt of a user during an interactive session. The chatbot system filters the prompt of the user based on a set of platform policies and generates a response based on the filtering of the prompt of the user, and communicates the response to the client system.

Abstract: A polyolefin-polydiorganosiloxane block copolymer may be prepared by Piers-Rubinsztajn reaction.

Abstract: A system includes a gas turbine system including a compressor, a combustor, a turbine, and an exhaust section. The system also includes multiple sensors coupled to components of the gas turbine system. The system further includes a controller communicatively coupled to the gas turbine system and the multiple sensors and configured to control operations of the gas turbine system, wherein the controller is configured to calculate a surrogate value for turbine exit Mach number based on the feedback from the multiple sensors and to utilize the surrogate value to derive a control action for the gas turbine system.

Abstract: Systems, methods, and apparatuses are described for determining compliance with a plurality of restrictions associated with one or more devices in an organization. First text indicating restrictions may be received, and second text indicating a current configuration of one or more devices may be received. Both sets of text may be processed by, e.g., removing a portion of the text based on a predetermined list of terms and simplifying the text using a lemmatization algorithm. A first vector and second vector may be generated based on the processed sets of text, and each vector may be weighted based on an inverse frequency of words in their respective text. Each vector may be normalized based on semantic analysis. The two vectors may be compared. Based on the comparison, third text corresponding to a portion of the second vector may be generated and transmitted to a third computing device.

Abstract: A machine for comminuting laminated glass members, such as automotive windshields and architectural glass, comprises infeed rollers feeding the member over a breaker bar, where an impactor assembly breaks the glass into small fragments and the plastic disposed between layers of the glass member into larger fragments, so that a size-based separation may be employed. The speed of the infeed rollers is controlled responsive to the thickness of the glass member.

Abstract: A vascular occlusion catheter for at least partial occlusion of a target vessel includes proximal and distal shafts, with an occlusion balloon connected therebetween. The proximal shaft has a proximal internal lumen, in fluid communication with the occlusion balloon. The distal shaft has a distal internal lumen. A hypotube having an internal lumen extends through the proximal lumen and the occlusion balloon and into communication with the distal lumen. The catheter includes at least one of (i) a distal sensor positioned within the distal lumen and facing an opening formed in the distal shaft, or (ii) the proximal shaft further includes a sensor lumen, and a proximal sensor is positioned within the sensor lumen and facing an opening formed in the proximal shaft. A display hub is mounted to the proximal shaft, and is electrically connected with the at least one of the distal sensor or the proximal sensor.

Abstract: A handgun simulation assembly that mates a virtual reality (VR) controller having a trigger finger button with a handgun grip and trigger in order to better simulate the feel of a typical handgun for a VR environment. The handgun simulation assembly includes a handgun body with a trigger translation subassembly for translating the horizontal motion of the trigger blade pull to a vertical translational action to depress the trigger finger button of the VR controller. A tensioning mechanism is incorporated in the trigger translation subassembly to simulate the feel of trigger resistance that is found in a physical handgun. By mating commercially available VR controllers with realistic handgun grips and triggers, users of the handgun simulation assembly are provided with a more realistic handgun experience when in a VR environment.

Abstract: A handgun simulation assembly that mates a virtual reality (VR) controller having a trigger finger button with a handgun grip and trigger in order to better simulate the feel of a typical handgun for a VR environment. The handgun simulation assembly includes a handgun body with a mating cradle that is designed to receive and hold a VR controller. The mating cradle has an engaged position where the VR controller is affixed to the handgun body and an unengaged position where the VR controller is released. When the mating cradle is in the engaged position, the VR controller can be oriented such that the trigger finger button is positioned downward, and the control pad is positioned rearward and facing the user. The mating cradle allows various subassemblies to access the buttons on the VR controller to provide a more realistic handgun experience when in a VR environment.

Abstract: A handgun simulation assembly that mates a virtual reality (VR) controller having a trigger finger button with a handgun grip and trigger in order to better simulate the feel of a typical handgun for a VR environment. The handgun simulation assembly includes a handgun body with a magazine release subassembly for transferring the depression of a magazine release button on the handgun grip to a translational action to depress the side button of the VR controller. Depressing the magazine release button can also cause a magazine weight suspended inside the handgun grip to at least partially drop downward in the handgun grip to simulate an actual magazine drop. By mating commercially available VR controllers with realistic handgun grips and triggers, users of the handgun simulation assembly are provided with a more realistic handgun experience when in a VR environment.

Abstract: Systems, methods, and apparatuses are described for determining compliance with a plurality of restrictions associated with one or more devices in an organization. First text indicating restrictions may be received, and second text indicating a current configuration of one or more devices may be received. Both sets of text may be processed by, e.g., removing a portion of the text based on a predetermined list of terms and simplifying the text using a lemmatization algorithm. A first vector and second vector may be generated based on the processed sets of text, and each vector may be weighted based on an inverse frequency of words in their respective text. Each vector may be normalized based on semantic analysis. The two vectors may be compared. Based on the comparison, third text corresponding to a portion of the second vector may be generated and transmitted to a third computing device.

Abstract: An occlusion catheter system includes a proximal hub having an inflation connection port and an inflation pathway. An inflation catheter member is connected to the proximal hub and has an inflation lumen. A stiffener member defines a longitudinal axis. The proximal end of the stiffener member is connected to the proximal hub. The stiffener member extends through a portion of the inflation lumen. An occlusion balloon has a proximal balloon end and a distal balloon end. A distal catheter member is positioned substantially on the longitudinal axis and is connected to the distal end of the stiffener member. An atraumatic tip is positioned on a distal end of the distal catheter member. The atraumatic tip has a substantially circular profile in a relaxed configuration. A pressure sensor is connected to the occlusion catheter system distally relative to the occlusion balloon and is connected to a processor by electrical wiring.