Patents by Inventor David Stein

David Stein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190277869
    Abstract: An analyzer system for in vitro diagnostics includes a sample handler module having a robot arm that delivers samples from drawers into carriers on a linear synchronous motor automation track. Samples are delivered via the automation track to individual track sections associated with individual analyzer modules. Analyzer modules aspirate sample portions directly from the sample carriers and perform analysis thereon.
    Type: Application
    Filed: July 19, 2017
    Publication date: September 12, 2019
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: David STEIN, Roy BARR, Mark EDWARDS, Colin MELLARS, Thomas J. BAO, Charles V. CAMMARATA, Benjamin S. POLLACK, Baris YAGCI
  • Patent number: 10412099
    Abstract: Various systems, mediums, and methods may involve a data engine with various components. For example, a system with the data engine may include a segmentation component, an asset preparation component, a clustering component, a variable generation component, and classification component. As such, the system may determine a number of assets associated with a number of activities of one or more accounts. Further, the system may determine various links associated with the number of assets. As such, the system may detect an attack and/or an attack trend associated with the one or more accounts based on the various links associated with the number assets. Further, the system may generate a notification that indicates the attack and/or the attack trend detected.
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: September 10, 2019
    Assignee: PayPal, Inc.
    Inventors: Adam Cohen, David Stein, Itzik Levi
  • Patent number: 10300149
    Abstract: Compositions and methods for enhancing delivery of molecules, e.g. biological agents, into cells are described. The composition is a conjugate of the biological agent, preferably a nucleic acid analog having a substantially uncharged backbone, covalently linked to a peptide transporter moiety as described. Conjugation of the peptide transporter to a substantially uncharged nucleic acid analog, such as a morpholino oligomer, is also shown to enhance binding of the oligomer to its target sequence and enhance antisense activity.
    Type: Grant
    Filed: January 10, 2017
    Date of Patent: May 28, 2019
    Assignee: SAREPTA THERAPEUTICS, INC.
    Inventors: Patrick L. Iversen, Hong M. Moulton, Michelle H. Nelson, David A. Stein, Andrew D. Kroeker
  • Publication number: 20190075131
    Abstract: Methods and systems are disclosed for dynamic detection of geo-location spoofing by a networked device, such as fraudulent client connections to a server, in which the connection is made using an internet protocol (IP) tunneling as may be provided by a virtual private network (VPN) connection. A user of a client device may employ spoofing of IP-geo location mechanisms and IP classification for various reasons, such as gaining access to services that are not allowed in certain locations (e.g., certain movie and television content providers); browsing server data while maintaining a higher level of anonymity; and performing fraudulent actions on the server. Detecting a false geographic location (e.g. as indicated by IP address) is helpful for improving computer system security, and for evaluating whether access to particular digital resources should be provided.
    Type: Application
    Filed: July 31, 2018
    Publication date: March 7, 2019
    Inventors: Avihay Nathan, Uri Arad, Oded Argon, David Stein, Lev Faivishevsky, Roi Lupo
  • Publication number: 20190065596
    Abstract: Placing an event into a particular cluster can allow various inferences about the event. A new payment transaction that looks similar to a previously identified cluster of mostly fraudulent payment transactions, for example, may be higher risk. The present disclosure includes structural data improvements to the way that online clustering of events (which may include web events and not just payment transactions) occurs. A new event can be classified into a particular segment very quickly using feature table searching, which can allow for better decision making when a short timeframe is required (e.g. transaction processing, online advertising, etc.).
    Type: Application
    Filed: August 29, 2017
    Publication date: February 28, 2019
    Inventors: Avishay Meron, Xing Wang, Adam Cohen, Chunmao Ran, David Stein
  • Publication number: 20190051157
    Abstract: A system that receives and analyzes a connected vehicle's safety feature activation and the location of activation on a road to determine if a hazard condition exist and providing an alert on a subscriber's vehicle or wireless device. Weather information for the location of the activation, highway engineering information for the location of the activation and other connected vehicles' safety feature activation at the location are also considered in the determination if the hazardous condition exists on the road. The hazardous condition alert can also be sent to the highway transportation department so that the hazardous condition can be mitigated.
    Type: Application
    Filed: October 15, 2018
    Publication date: February 14, 2019
    Inventor: David Stein
  • Patent number: 10115151
    Abstract: The number of users viewing a given variable directly affects the rate of change and/or outcome of said variable. In the case of eCommerce, pricing of products and/or services is based upon a user accessing a website on which products and/or services are for sale. An initial price indicia associator associates initial price indicia with the products and/or services files. The initial pricing can be based upon historical indicia or the engine itself. Thereafter, a price indicia adjuster adjusts the pricing responsive to user access of the website or related website. A user interface meter shown on the website indicates to potential buyers how much interest there is in the product and/or service being sold so that peer activity is exhibited to potential buyers to encourage sales and impulsive buying behavior. Pricing is dynamic and adjusts in real-time at a rate determined by the amount of users accessing the website.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: October 30, 2018
    Assignee: PEERACTIVE INC.
    Inventors: David Stein, Nicholas Rosenthal, Robert Arbittier, Nir Golan
  • Patent number: 10102743
    Abstract: A system that receives and analyzes a connected vehicle's safety feature activation and the location of activation on a road to determine if a hazard condition exist and providing an alert on a subscriber's vehicle or wireless device. Weather information for the location of the activation, highway engineering information for the location of the activation and other connected vehicles' safety feature activation at the location are also considered in the determination if the hazardous condition exists on the road. The hazardous condition alert can also be sent to the highway transportation department so that the hazardous condition can be mitigated.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: October 16, 2018
    Assignee: Bosch Automotive Service Solutions Inc.
    Inventor: David Stein
  • Patent number: 10058390
    Abstract: Featured are systems, devices and apparatuses for use in minimally invasive surgical, diagnostic or therapeutic methods and/or techniques, in particular methods and/or techniques for a mammalian throat. In particular embodiments, a dexterity apparatus including one or more dexterity devices is featured, where each of the dexterity devices comprises surgical tools and each is configured and arranged with end-tip dexterity for enhanced manipulation. A portion of the dexterity devices is snake like, which is re-configurable (i.e., can be bent) so as to in effect maneuver the surgical tool and put the tool in a desired position with respect to the surgical site. Another portion of the dexterity device includes the surgical tool thereby providing the capability of performing surgical actions such as sewing, gripping, soft tissue manipulation, cutting and suction of saliva, blood and other materials from the surgical site.
    Type: Grant
    Filed: January 14, 2013
    Date of Patent: August 28, 2018
    Assignee: The Johns Hopkins University
    Inventors: Nabil Simaan, Russell H. Taylor, Paul Flint, Gregory Chirikjian, David Stein
  • Patent number: 10038712
    Abstract: Methods and systems are disclosed for dynamic detection of fraudulent client connections to a server, in which, for example, the connection is made using an internet protocol (IP) tunneling technology such as networking on a virtual private network (VPN) and making the connection via a VPN tunnel in order to obfuscate the client IP address, in which a user of a client device may employ spoofing of IP-geo location mechanisms and IP classification on the server side. Such a user may have various motivations for obfuscating the client device's geo-location by using an IP tunnel when connecting to a server such as gaining access to services that are not allowed in certain locations (e.g., certain movie and television content providers); browsing server data while maintaining a higher level of anonymity; and performing fraudulent actions on the server.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: July 31, 2018
    Assignee: PAYPAL, INC.
    Inventors: Avihay Nathan, Uri Arad, Oded Argon, David Stein, Lev Faivishevsky, Roi Lupo
  • Publication number: 20170368203
    Abstract: Compositions and methods for enhancing delivery of molecules, e.g. biological agents, into cells are described. The composition is a conjugate of the biological agent, preferably a nucleic acid analog having a substantially uncharged backbone, covalently linked to a peptide transporter moiety as described. Conjugation of the peptide transporter to a substantially uncharged nucleic acid analog, such as a morpholino oligomer, is also shown to enhance binding of the oligomer to its target sequence and enhance antisense activity.
    Type: Application
    Filed: January 10, 2017
    Publication date: December 28, 2017
    Inventors: Patrick L. Iversen, Hong M. Moulton, Michelle H. Nelson, David A. Stein
  • Publication number: 20170374083
    Abstract: Various systems, mediums, and methods may involve a data engine with various components. For example, a system with the data engine may include a segmentation component, an asset preparation component, a clustering component, a variable generation component, and classification component. As such, the system may determine a number of assets associated with a number of activities of one or more accounts. Further, the system may determine various links associated with the number of assets. As such, the system may detect an attack and/or an attack trend associated with the one or more accounts based on the various links associated with the number assets. Further, the system may generate a notification that indicates the attack and/or the attack trend detected.
    Type: Application
    Filed: June 22, 2016
    Publication date: December 28, 2017
    Inventors: Adam Cohen, David Stein, Itzik Levi
  • Publication number: 20170372317
    Abstract: Rapidly handling large data sets can be a challenge, particularly in situations where there are millions or even hundreds of millions of database records. Sometimes, however, a service level agreement necessitates that a service return a response to a query in a small amount of time. Database organization techniques can be used that reduce potentially large datasets to smaller groups (neighbors) based on uncommon but shared attributes, in various instances. Using a limited set of related records, queries can be answered using a focused approximation based on characteristics of various identified clusters of records in the set of related records. A particular record may also be associated with an existing cluster of records based on that record's similarities to records in the cluster.
    Type: Application
    Filed: May 11, 2017
    Publication date: December 28, 2017
    Inventors: Xing Wang, Adam Cohen, David Stein, Chunmao Ran, Itzik Levi, Doron Hai-Reuven
  • Publication number: 20170329840
    Abstract: Disclosed are systems and methods for improving interactions with and between computers in a search system supported by or configured with search servers, applications or platforms. The systems interact to identify and retrieve data across platforms, which data can be used to improve the quality of results data used in processing interactions between or among processors in such systems. The disclosed systems and methods provide a novel framework for automatically analyzing items, including real-world items and digital content items, in order to determine their attributes (e.g., characteristics, features, and the like), and based on the determined attributes, generating a user interface (UI) that displays the items and their respective attributes in an interactive, dynamically updatable and searchable multidimensional display.
    Type: Application
    Filed: May 15, 2017
    Publication date: November 16, 2017
    Inventors: James McGOWAN, Nir GOLAN, Robert ARBITTIER, Joshua KAUFMAN, Nicholas ROSENTHAL, David STEIN, Alyssa BIRNBAUM, Cherian CHACKO
  • Publication number: 20170235788
    Abstract: Methods and systems for generating queries from a behavioral index model are described. According to various embodiments, a system receives a query input including one or more search terms from a client device associated with a member profile. The system generates a query from the one or more search terms and one or more profile terms. The system causes one or more query machines to search one or more inverted indices using the query and receives one or more result of documents distributed across the inverted indices. The system generates an ordered list of the one or more result sets and causes presentation of the ordered list at a client device associated with the member profile.
    Type: Application
    Filed: February 10, 2017
    Publication date: August 17, 2017
    Inventors: Fedor Vladimirovich Borisyuk, Krishnaram Kenthapadi, David Stein, Parul Jain, Bo Zhao
  • Publication number: 20170236073
    Abstract: Methods and systems for developing a behavioral index model are described. According to various embodiments, the system accesses a set of behavioral data stored in association with a set of member profiles. The system generates a set of training data from the set of behavioral data and generates a set of feature vectors from the set of training data. The system generates a behavioral index model from the set of training data and the set of feature vectors. The system then generates a tuned behavioral index model from the behavioral index model by tuning a threshold of the behavioral index model using a precision recall curve.
    Type: Application
    Filed: February 10, 2017
    Publication date: August 17, 2017
    Inventors: Fedor Vladimirovich Borisyuk, Krishnaram Kenthapadi, David Stein, Parul Jain, Bo Zhao
  • Publication number: 20170186313
    Abstract: A system that receives and analyzes a connected vehicle's safety feature activation and the location of activation on a road to determine if a hazard condition exist and providing an alert on a subscriber's vehicle or wireless device. Weather information for the location of the activation, highway engineering information for the location of the activation and other connected vehicles' safety feature activation at the location are also considered in the determination if the hazardous condition exists on the road. The hazardous condition alert can also be sent to the highway transportation department so that the hazardous condition can be mitigated.
    Type: Application
    Filed: December 28, 2015
    Publication date: June 29, 2017
    Inventor: David Stein
  • Patent number: 9639891
    Abstract: The number of users viewing a given variable directly affects the rate of change and/or outcome of said variable. In the case of eCommerce, pricing of products and/or services is based upon a user accessing a website on which products and/or services are for sale. An initial price indicia associator associates initial price indicia with the products and/or services files. The initial pricing can be based upon historical indicia or the engine itself. Thereafter, a price indicia adjuster adjusts the pricing responsive to user access of the website or related website. A user interface meter shown on the website indicates to potential buyers how much interest there is in the product and/or service being sold so that peer activity is exhibited to potential buyers to encourage sales and impulsive buying behavior. Pricing is dynamic and adjusts in real-time at a rate determined by the amount of users accessing the website.
    Type: Grant
    Filed: March 27, 2012
    Date of Patent: May 2, 2017
    Assignee: PEERACTIVE, INC.
    Inventors: David Stein, Nicholas Rosenthal, Robert Arbittier, Nir Golan
  • Patent number: 9572899
    Abstract: Compositions and methods for enhancing delivery of molecules, e.g. biological agents, into cells are described. The composition is a conjugate of the biological agent, preferably a nucleic acid analog having a substantially uncharged backbone, covalently linked to a peptide transporter moiety as described. Conjugation of the peptide transporter to a substantially uncharged nucleic acid analog, such as a morpholino oligomer, is also shown to enhance binding of the oligomer to its target sequence and enhance antisense activity.
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: February 21, 2017
    Assignee: AVI BIOPHARMA, INC.
    Inventors: Patrick L. Iversen, Hong M. Moulton, Michelle H. Nelson, Andrew D. Kroeker, David A. Stein
  • Patent number: 9497253
    Abstract: A computer system can provide user interfaces and back-end operations to facilitate review of the web requests. The system can detect whether an operation of an application called by a web request includes a review tag or a call to a review method. If a review tag or a call to a review method is detected, the middleware can initiate a review process that can include receiving input from a client device associated with a human reviewer. Upon receiving approval by the reviewer, the web request can be generated using a saved version of the original web request and executed. Thus, this review process can run without requiring that code for reviewing the web request be contained within the web request or the application called by the web request.
    Type: Grant
    Filed: April 9, 2014
    Date of Patent: November 15, 2016
    Assignee: Dropbox, Inc.
    Inventor: David Stein