Abstract: The present invention provides hepcidin analogues with improved in vivo half lives, and related pharmaceutical compositions and methods of use thereof.

Abstract: A respiratory mask can include one or a plurality of force sensors configured to detect a force imparted to a user's skin. Output from the one or more sensors can be represented in a way useful to the patient or healthcare provider for adjusting the mask to achieve a desired fitment. A representation of the detected forces can be displayed on a separate display device or on the mask.

Abstract: A radio-frequency identification (RFID) tag, or tag, is affixed to a particular item and stores unique identifying information about that item. It can be queried with a reader that transmits wireless signals to the tag and receive the tag's responses, which can be correlated with information in inventory records. Conventionally, when a reader stops receiving a tag's responses to these queries, the inventory records are updated to show that the tag and associated item have been removed from the inventory. But a tag can stop producing detectable response for other reasons, including being too close to other tags, so simply removing the tag and item can lead to inaccurate inventory records. Stateful inventory technology address this problem by maintaining and transitioning tags among different states, including a stale state for tags that have not been read recently, depending on when and where the tags were last read.

Abstract: Antimicrobial material which is a composite of a matrix component comprising a flexible hydrophilic polymer foam or fiber matrix comprising two matrix faces providing a release face and a reverse face or two release faces, and therebetween a structural matrix framework defining a network of cells having a cell network surface and therein a network of pores or cell openings, and a powder charge component comprising antimicrobial additive or wound care additive, wherein said powder charge is comprised at one said release face or both said faces and/or within said cell network wherein said composite is an assembly of pre-formed matrix component and powder charge component; and asymmetric material which is asymmetric having regard to distribution of said powder charge therein; and material wherein said power charge comprises flowing agent and/or bulking agent and/or binder and wherein said additive and/or flowing agent is co-located with said bulking agent and/or said binder; devices comprising said composite, me

Abstract: A reaming tool includes a housing having a connection at one end for coupling to a pipe string. The housing defines at least one of a rotor and a stator of a turbine. A rotor shaft is rotatably supported on the housing. The rotor shaft has an interior passage and defines the other of a stator and a rotor of the turbine. The rotor shaft has a coupling at one end to attach a well intervention tool. A flow diverter is disposed within the housing. The flow diverter comprises ports to selectively direct flow of fluid from an interior of the housing to either (i) an annular space between the housing and the rotor shaft, or (ii) the interior passage of the rotor shaft. The flow diverter is operable to change direction of the flow of fluid by changing a flow rate of the flow of fluid.

Abstract: An antimicrobial material including a composite of a matrix component comprising a flexible hydrophilic polymer foam or fiber matrix comprising two matrix faces providing a release face and a reverse face or two release faces, and therebetween a structural matrix framework defining a network of cells having a cell network surface and therein a network of pores or cell openings, and a powder charge component comprising antimicrobial additive or wound care additive, wherein said powder charge is comprised at one said release face or both said faces and/or within said cell network.

Abstract: A tooling assembly for a machine having an automatic tool changing system includes a tool body disposed about a rotational axis and defining an internal passage operable to flow a fluid therein. The internal passage includes an inlet, stem channel, first and second curved channels, and first and second transition portions. The inlet is configured to receive the fluid from the machine. First and second outlets are open through an exterior of the tool body. The stem channel is in fluid communication with the inlet and ends at a beginning of the first and second transition portions. The first curved channel extends from the first transition portion to the first outlet. The second curved channel extends from the second transition portion to the second outlet.

Abstract: The present disclosure is directed toward a tooling assembly for a machine having an automatic tool changing system. The tooling assembly includes a holder, a tool body, and an internal passage defined within and extending through the holder and the tool body. The holder includes a machine interface configured to engage with a spindle of the machine. The internal passage is operable to have a coolant fluid flow within, and has a stem channel and a curved channel extending from the stem channel.

Abstract: Indexing a data corpus to a set of multidimensional points, including: generating a set of points in a multidimensional space; identifying, for each sample in a plurality of samples in a data corpus, a nearest point in the set of points; and generating an index mapping each sample with the nearest point in the set of points.

Abstract: Flexible polyurethane (PU) material which comprises a flexible hydrophilic polyurethane foam porous matrix comprising two matrix faces and therebetween a structural matrix framework defining a network of cells, having a cell network surface and therein a network of pores and a powder charge comprising one or more additives loaded in said structural matrix framework wherein said material is a foamed polymer of a system comprising an isocyanate prepolymer or monomer phase and an aqueous phase, wherein said system comprises one or more slurry phases or solid concentrates of said powder charge, or an insoluble portion thereof, as said isocyanate phase or part thereof and/or as said aqueous phase or part thereof and/or in a carrier liquid phase; and/or comprising a powder charge of silver salt loaded in said structural matrix framework in a population of silver salt particles defined by particle size distribution about a mean particle size of greater than or equal to 1 micron, said material comprising silver sa

Abstract: An antimicrobial material including a composite of a matrix component comprising a flexible hydrophilic polymer foam or fiber matrix comprising two matrix faces providing a release face and a reverse face or two release faces, and therebetween a structural matrix framework defining a network of cells having a cell network surface and therein a network of pores or cell openings, and a powder charge component comprising antimicrobial additive or wound care additive, wherein said powder charge is comprised at one said release face or both said faces and/or within said cell network.

Abstract: Indexing a data corpus to a set of multidimensional points, including: generating a set of points in a multidimensional space; identifying, for each sample in a plurality of samples in a data corpus, a nearest point in the set of points; and generating an index mapping each sample with the nearest point in the set of points.

Abstract: The invention herein is a method and system for controlling a fleet of autonomous vehicles (300) for ridesharing, wherein the method comprising the steps of: receiving a request (S1) from a first user or group of users for pick-up by an autonomous vehicle out of said fleet of vehicles (300), said user request further comprising a privacy setting, controlling the state of a privacy barrier device (310a, 310b) of a first autonomous vehicle (301) according to said privacy setting, and controlling said first autonomous vehicle (301) to pick up said first user or group of users.

Abstract: Disclosed herein are embodiments of a wound care material with a material which is a composite of a matrix component comprising a flexible hydrophilic polymer foam or fiber matrix comprising two matrix faces providing a release face and a reverse face or two release faces, and therebetween a structural matrix framework defining a network of cells having a cell network surface and therein a network of pores or cell openings, and a powder charge component comprising antimicrobial additive or wound care additive, wherein said powder charge is comprised at one said release face or both said faces and/or within said cell network.

Abstract: Flexible polyurethane (PU) material which comprises a flexible hydrophilic polyurethane foam porous matrix comprising two matrix faces and therebetween a structural matrix framework defining a network of cells, having a cell network surface and therein a network of pores and a powder charge comprising one or more additives loaded in said structural matrix framework wherein said material is a foamed polymer of a system comprising an isocyanate prepolymer or monomer phase and an aqueous phase, wherein said system comprises one or more slurry phases or solid concentrates of said powder charge, or an insoluble portion thereof, as said isocyanate phase or part thereof and/or as said aqueous phase or part thereof and/or in a carrier liquid phase; and/or comprising a powder charge of silver salt loaded in said structural matrix framework in a population of silver salt particles defined by particle size distribution about a mean particle size of greater than or equal to 1 micron, said material comprising silver salt

Abstract: A thread tap includes a shaft and teeth. The shaft includes helical passages from the threading end to the base end of the shaft. Each passage opens through an aperture in the threading end. A second tap includes a cap and the shaft includes an axially extending passage. The cap is coupled to the threading end and at least partially defines apertures in fluid communication with the passage and the exterior of the tap. A third tap includes teeth spaced apart by a plurality of linear flutes. The shaft includes a central passage and a plurality of flute passages. Each flute passage extends radially outward from a common location in the central passage to a corresponding one of the flutes. The central passage is closed to a terminal end of the threading end.

Abstract: The present disclosure is directed toward a tooling assembly for a machine having an automatic tool changing system. The tooling assembly includes a holder, a tool body, and an internal passage defined within and extending through the holder and the tool body. The holder includes a machine interface configured to engage with a spindle of the machine. The internal passage is operable to have a coolant fluid flow within, and has a stem channel and a curved channel extending from the stem channel.

Abstract: The present disclosure is directed toward a tooling assembly for a machine having an automatic tool changing system. The tooling assembly includes a holder, a tool body, and an internal passage defined within and extending through the holder and the tool body. The holder includes a machine interface configured to engage with a spindle of the machine. The internal passage is operable to have a coolant fluid flow within, and has a stem channel and a curved channel extending from the stem channel.

Abstract: Antimicrobial material which is a composite of a matrix component comprising a flexible hydrophilic polymer foam or fiber matrix comprising two matrix faces providing a release face and a reverse face or two release faces, and therebetween a structural matrix framework defining a network of cells having a cell network surface and therein a network of pores or cell openings, and a powder charge component comprising antimicrobial additive or wound care additive, wherein said powder charge is comprised at one said release face or both said faces and/or within said cell network wherein said composite is an assembly of preformed matrix component and powder charge component; and asymmetric material which is asymmetric having regard to distribution of said powder charge therein; and material wherein said power charge comprises flowing agent and/or bulking agent and/or binder and wherein said additive and/or flowing agent is co-located with said bulking agent and/or said binder; devices comprising said composite, met

Abstract: A flotation device for a wellbore tubular has a flotation disk having a tapered exterior profile. A maximum external diameter of the flotation disk is such to enable free longitudinal movement within the wellbore tubular. A plurality of locking segments each has a tapered interior profile cooperatively engageable with the tapered exterior profile. Each locking segment has gripping elements on an exterior surface thereof to engage an inner wall of the wellbore tubular. The tapered exterior profile and the tapered interior profile cooperate to expand a diameter of the locking segments as profile engagement increases.