Patents by Inventor David Thomas Davies

David Thomas Davies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
    Patent number: 7534793
    Abstract: Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man
    Type: Grant
    Filed: September 2, 2005
    Date of Patent: May 19, 2009
    Assignee: SmithKline Beecham p.l.c.
    Inventors: David Thomas Davies, Graham Elgin Jones, Andrew P Lightfoot, Roger Edward Markwell, Neil David Pearson
  • Compounds
    Patent number: 7498326
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man. The piperidine derivatives include compounds of formula (I): wherein RA, AB, n, R3, R2 and R4 are defined herein. For example, RA is an optionally substituted bicyclic carbocyclic or heterocyclic ring system, and R4 is a group U-R5 in which R5 is an optionally substituted bicyclic heterocyclic ring system as defined herein (e.g. optionally substituted pyrido [3,2, -b][1,4] thiazin-yl).
    Type: Grant
    Filed: June 25, 2003
    Date of Patent: March 3, 2009
    Assignee: Glaxo Group Limited
    Inventors: Jeffrey Michael Axten, Robert A Daines, David Thomas Davies, Timothy Francis Gallagher, Graham Elgin Jones, William Henry Miller, Neil David Pearson, Israil Pendrak
  • Heterocyclic Compounds, their Preparation and their Use as Antibacterials
    Publication number: 20090036433
    Abstract: Tricyclic nitrogen containing compounds of formula (I) and their use as antibacterials.
    Type: Application
    Filed: December 15, 2006
    Publication date: February 5, 2009
    Inventors: Nathalie Caileau, David Thomas Davies, Alan Joseph Hennessy, Graham Elgin Jones, Timothy James Miles, Neil David Pearson
  • Compounds
    Publication number: 20080280892
    Abstract: Tricyclic nitrogen containing compounds and their use as antibacterials.
    Type: Application
    Filed: October 17, 2006
    Publication date: November 13, 2008
    Inventors: Nathalie Cailleau, David Thomas Davies, Joel Michael Esken, Alan Joseph Hennessy, Senthil Kumar Kusalakumari Sukumar, Roger Edward Markwell, Timothy James Miles, Neil David Pearson
  • Compounds
    Publication number: 20080221110
    Abstract: Tricyclic nitrogen containing compounds and their use as antibacterials
    Type: Application
    Filed: October 17, 2006
    Publication date: September 11, 2008
    Inventors: Nathalie Cailleau, David Thomas Davies, Joel Michael Esken, Alan Joseph Hennessy, Senthil Kumar Kusalakumari Sukumar, Roger Edward Markwell, Timothy James Miles, Neil David Pearson
  • Quinolines and nitrogenated derivative thereof substituted in 4-position by a piperidine-containing moiety and their use as antibacterial agents
    Patent number: 7205408
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: April 17, 2007
    Assignee: SmithKline Beecham, p.l.c.
    Inventors: David Thomas Davies, Graham Elgin Jones, Roger Edward Markwell, William Miller, Neil David Pearson
  • Nitrogen-containing bicyclic heterocycles for use as antibacterials
    Patent number: 7141564
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Grant
    Filed: May 24, 2002
    Date of Patent: November 28, 2006
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Gerald Brooks, David Thomas Davies, Graham Elgin Jones, Roger Edward Markwell, Neil David Pearson
  • Aminopiperidine derivatives as antibacterials
    Patent number: 7001913
    Abstract: Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Grant
    Filed: July 17, 2000
    Date of Patent: February 21, 2006
    Assignee: SmithKline Beecham P.L.C.
    Inventors: David Thomas Davies, Andrew Lightfoot, Roger Edward Markwell, Neil David Pearson
  • Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
    Publication number: 20060014749
    Abstract: Aminopiperidine derivatives of formula (I) and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: September 2, 2005
    Publication date: January 19, 2006
    Inventors: David Thomas Davies, Graham Jones, Andrew Lightfoot, Roger Markwell, Neil Pearson
  • Aminopiperidine quinolines and their azaisosteric analogues with antibacterical activity
    Patent number: 6962917
    Abstract: Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Grant
    Filed: July 25, 2001
    Date of Patent: November 8, 2005
    Assignee: SmithKline Beecham P.L.C.
    Inventors: David Thomas Davies, Graham Elgin Jones, Andrew P Lightfoot, Roger Edward Markwell, Neil David Pearson
  • Quinoline derivatives as antibacterials
    Patent number: 6911442
    Abstract: The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt and/or N-oxide thereof: corresponding novel medicaments, pharmaceutical compositions and/or methods of
    Type: Grant
    Filed: June 13, 2000
    Date of Patent: June 28, 2005
    Assignee: SmithKline Beecham p.l.c.
    Inventors: David Thomas Davies, Roger Edward Markwell, Neil David Pearson, Andrew Kenneth Takle
  • Medicaments
    Publication number: 20040198756
    Abstract: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Application
    Filed: May 24, 2004
    Publication date: October 7, 2004
    Inventors: David Thomas Davies, Graham Elgin Jones, Roger Edward Markwell, Neil David Pearson
  • Nitrogen-containing bicyclic heterocycles for use as antibacterials
    Publication number: 20040171620
    Abstract: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives hereof useful in methods of treatment of bacterial infections in mammals, particularly man.
    Type: Application
    Filed: April 6, 2004
    Publication date: September 2, 2004
    Inventors: Gerald Brooks, David Thomas Davies, Graham Elgin Jones, Roger Edward Markwell, Neil David Pearson
  • Quinolines and nitrogenated derivative therof substituted in 4-position by a piperidine-containing moiety and their use as antibacterial agents
    Publication number: 20040138219
    Abstract: Piperidine derivatives of formula (I) and pharmaceutically derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: January 26, 2004
    Publication date: July 15, 2004
    Inventors: David Thomas Davies, Graham Elgin Jones, Roger Edward Markwell, William Miller, Neil David Pearson
  • Quinoline derivatives as antibacterials
    Publication number: 20040053928
    Abstract: Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: September 4, 2003
    Publication date: March 18, 2004
    Inventors: David Thomas Davies, Roger Edward Markwell, Neil David Pearson
  • Aminopiperidine quinolines and their azaisosteric analogues with antibacterical activity
    Publication number: 20040038998
    Abstract: Aminopiperidine derivatives of formula (I) and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Application
    Filed: August 28, 2003
    Publication date: February 26, 2004
    Inventors: David Thomas Davies, Graham Elgin Jones, Andrew Peightfoot, Roger Edward Markwell, Neil David Pearson
  • Indole derivatives as 5-HT receptor antagonist
    Patent number: 6638953
    Abstract: The invention relates to heterocyclic compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of CNS disorders such as anxiety.
    Type: Grant
    Filed: January 22, 2001
    Date of Patent: October 28, 2003
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Laramie Mary Gaster, Paul Adrian Wyman, Keith Raymond Mulholland, David Thomas Davies, David Malcolm Duckworth, Ian Thomson Forbes, Graham Elgin Jones
  • Quinoline derivatives and their use as antibacterial agents
    Patent number: 6602882
    Abstract: Piperidine derivatives and pharmaceutical derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
    Type: Grant
    Filed: May 24, 2001
    Date of Patent: August 5, 2003
    Assignee: SmithKline Beecham p.l.c.
    Inventors: David Thomas Davies, Roger Edward Markwell, Neil David Pearson, Andrew Kenneth Takle
  • Indole derivatives as 5-HT receptor antagonist
    Publication number: 20030105139
    Abstract: The invention relates to heterocyclic compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of CNS disorders such as anxiety.
    Type: Application
    Filed: January 22, 2001
    Publication date: June 5, 2003
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Laramie Mary Gaster, Paul Adrian Wyman, Keith Raymond Mulholland, David Thomas Davies, David Malcolm Duckworth, Ian Thomson Forbes, Graham Elgin Jones
  • Indole derivatives as 5-HT receptor antagonist
    Patent number: 6235758
    Abstract: A compound of formula (I) or a salt thereof: wherein: P1 is pyridiyl; P2 is phenyl; A is a bond or a chain of 1 to 5 atoms optionally substituted by C1-6 alkyl; R1 and R2 groups are each independently hydrogen, C1-6alkyl optionally substituted by NR12R13, C2-6alkenyl, C2-6alkynyl, cyano, halogen, CF3, NR12R13, CHO, OCF3, COR14, CH2OR14 or OR14 where R12, R13 and R14 are independently hydrogen or C1-6alkyl; n and m are independently 0, 1 or 2; R3 is hydrogen or C1-6 alkyl; R4 is a group of formula (i): in which: R6 and R7 are independently hydrogen, C1-6 alkyl optionally substituted by one or more fluorine atoms, C1-6alkylthio, C1-6alkoxy or halogen.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: May 22, 2001
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Laramie Mary Gaster, Paul Adrian Wyman, Keith Raymond Mulholland, David Thomas Davies, David Malcolm Duckworth, Ian Thomson Forbes, Graham Elgin Jones