Abstract: The invention relates to compounds of formula I wherein R1, R2 and - - - - - are as defined herein, pharmaceutical compositions comprising the compounds and methods of treating COVID-19 in a patient by administering therapeutically effective amounts of the compounds and methods of inhibiting or preventing replication of SARS-CoV-2 with the compounds.

Abstract: An electronic device identifier mapping and resolution system are disclosed which may be used to analyze various device identifiers associated with an online event initiated by a particular device in applying a matching algorithm to determine a unique device identifier and/or device profile for the device. Device identifiers provided from disparate sources (such as web browser cookies, network IP addresses, device-specific identifiers, application-specific identifiers, custom identifiers, probabilistic identifiers, etc.), including both deterministic and/or probabilistic identifiers, may be analyzed according to the matching algorithm to determine a device identifier associated with the device. Matching algorithms may be customized and configured to a high degree of complexity for respective entities, such as to analyze disparate device identifiers according to a variety of identifier comparison functions and matching tiers.

Abstract: A modular screen system includes a tubular member having an outer surface defining an outer diameter and an inner surface defining an inner diameter. The outer surface includes an opening and a recess extending about the opening. A flow control device is positioned at the opening in the recess, and a screen member is detachably mounted to the tubular in the recess. The screen member includes a filtering surface that does not project proudly of the outer surface.

Abstract: A modular screen system includes a tubular member having an outer surface defining an outer diameter and an inner surface defining an inner diameter. The outer surface includes an opening and a recess extending about the opening. A flow control device is positioned at the opening in the recess, and a screen member is detachably mounted to the tubular in the recess. The screen member includes a filtering surface that does not project proudly of the outer surface.

Abstract: An electronic device identifier mapping and resolution system are disclosed which may be used to analyze various device identifiers associated with an online event initiated by a particular device in applying a matching algorithm to determine a unique device identifier and/or device profile for the device. Device identifiers provided from disparate sources (such as web browser cookies, network IP addresses, device-specific identifiers, application-specific identifiers, custom identifiers, probabilistic identifiers, etc.), including both deterministic and/or probabilistic identifiers, may be analyzed according to the matching algorithm to determine a device identifier associated with the device. Matching algorithms may be customized and configured to a high degree of complexity for respective entities, such as to analyze disparate device identifiers according to a variety of identifier comparison functions and matching tiers.

Abstract: Embodiments of a combined overspeed and fuel stream selector system are provided. In an embodiment, the assembly includes a conduit network, a Discharge Select Valve (DSV), and a shutoff valve. The DSV is fluidly coupled to a primary fuel inlet, a secondary fuel inlet, and a primary fuel outlet included in the conduit network. The shutoff valve is fluidly coupled between the primary fuel inlet and the primary fuel outlet. In a standard operation mode, the shutoff valve is maintained in an open position, while fuel received at the primary fuel inlet is directed through the shutoff valve, through the DSV, and to the primary fuel inlet. Conversely, in a backup operation mode, the shutoff valve is closed to block fuel flow from the primary fuel inlet to the primary fuel outlet, while the DSV directs fuel flow received at the secondary fuel inlet to the primary fuel outlet.

Abstract: An electronic device identifier mapping and resolution system are disclosed which may be used to analyze various device identifiers associated with an online event initiated by a particular device in applying a matching algorithm to determine a unique device identifier and/or device profile for the device. Device identifiers provided from disparate sources (such as web browser cookies, network IP addresses, device-specific identifiers, application-specific identifiers, custom identifiers, probabilistic identifiers, etc.), including both deterministic and/or probabilistic identifiers, may be analyzed according to the matching algorithm to determine a device identifier associated with the device. Matching algorithms may be customized and configured to a high degree of complexity for respective entities, such as to analyze disparate device identifiers according to a variety of identifier comparison functions and matching tiers.

Abstract: A test sub having a housing with a first end, a second end, a bore, and an exterior portion of the housing including a coiled tubing connector may be used to test a connection with coiled tubing. The test sub includes a valve positioned within the bore. The second end of the housing may be inserted into coiled tubing and fluid may be pumped into the housing to test the connection between the connector and the coiled tubing. The test sub may be a housing that may be attached to a coiled tubing connector already connected to coiled tubing. A rod within the housing may be moved to an inserted position permitting communication between a pressure port of the housing and an exterior port of the coiled tubing connector. Fluid may be pumped into the pressure port to test the connection between the coiled tubing connector and the coiled tubing.

Abstract: An electronic device identifier mapping and resolution system are disclosed which may be used to analyze various device identifiers associated with an online event initiated by a particular device in applying a matching algorithm to determine a unique device identifier and/or device profile for the device. Device identifiers provided from disparate sources (such as web browser cookies, network IP addresses, device-specific identifiers, application-specific identifiers, custom identifiers, probabilistic identifiers, etc.), including both deterministic and/or probabilistic identifiers, may be analyzed according to the matching algorithm to determine a device identifier associated with the device. Matching algorithms may be customized and configured to a high degree of complexity for respective entities, such as to analyze disparate device identifiers according to a variety of identifier comparison functions and matching tiers.

Abstract: Embodiments of a combined overspeed and fuel stream selector system are provided. In an embodiment, the assembly includes a conduit network, a Discharge Select Valve (DSV), and a shutoff valve. The DSV is fluidly coupled to a primary fuel inlet, a secondary fuel inlet, and a primary fuel outlet included in the conduit network. The shutoff valve is fluidly coupled between the primary fuel inlet and the primary fuel outlet. In a standard operation mode, the shutoff valve is maintained in an open position, while fuel received at the primary fuel inlet is directed through the shutoff valve, through the DSV, and to the primary fuel inlet. Conversely, in a backup operation mode, the shutoff valve is closed to block fuel flow from the primary fuel inlet to the primary fuel outlet, while the DSV directs fuel flow received at the secondary fuel inlet to the primary fuel outlet.

Abstract: A test sub having a housing with a first end, a second end, a bore, and an exterior portion of the housing including a coiled tubing connector may be used to test a connection with coiled tubing. The test sub includes a valve positioned within the bore. The second end of the housing may be inserted into coiled tubing and fluid may be pumped into the housing to test the connection between the connector and the coiled tubing. The test sub may be a housing that may be attached to a coiled tubing connector already connected to coiled tubing. A rod within the housing may be moved to an inserted position permitting communication between a pressure port of the housing and an exterior port of the coiled tubing connector. Fluid may be pumped into the pressure port to test the connection between the coiled tubing connector and the coiled tubing.

Abstract: A gas turbine engine fuel supply system includes a primary gear pump and a secondary gear pump. The primary gear pump always actively delivers fuel to the downstream fuel system, and is sized to supply 100% of the burn flow needed at a select low demand condition. The secondary gear pump is sized to make up the remainder of the flow at high demand conditions, and actively delivers fuel to the downstream fuel system only during those conditions. To supply discharge fuel pressures in excess of gear pump capability, a supercharger pump is disposed upstream of the primary and secondary gear pumps. The supercharger pump is preferably activated only during high demand conditions as an additional energy conservation measure.

Abstract: A gas turbine engine fuel supply system includes a primary gear pump, a secondary gear pump, and a pump bypass valve. The primary gear pump always actively delivers fuel to the downstream fuel system, and is sized to supply 100% of the burn flow needed at a select low demand condition. The secondary gear pump is sized to make up the remainder of the flow at high demand conditions, and actively delivers fuel to the downstream fuel system only during those conditions. To supply discharge fuel pressures in excess of gear pump capability, a supercharger pump is disposed upstream of the primary and secondary gear pumps. The pump bypass valve is configured to regulate fuel pressure at the primary gear pump outlet to one of a plurality of preset differential pressures above one of a plurality of fuel load pressures and prevents reverse pressurization of the gear pumps.

Abstract: A system provides “fail fixed” functionality and allows a user to manually manipulate fuel flow to a gas turbine engine in the unlikely event the primary control means is unavailable. The fuel metering unit includes a fuel metering valve, a flow increase valve, and a flow decrease valve. The flow increase valve and flow decrease valves are both in fluid communication with the fuel metering valve and are each adapted to selectively receive fuel flow commands from a primary fuel flow command source and from a secondary fuel flow command source. The flow increase and decrease valves are responsive to the fuel flow commands to selectively control the position of the fuel metering valve.

Abstract: A gas turbine engine fuel supply system includes a primary gear pump and a secondary gear pump. The primary gear pump always actively delivers fuel to the downstream fuel system, and is sized to supply 100% of the burn flow needed at a select low demand condition. The secondary gear pump is sized to make up the remainder of the flow at high demand conditions, and actively delivers fuel to the downstream fuel system only during those conditions. To supply discharge fuel pressures in excess of gear pump capability, a supercharger pump is disposed upstream of the primary and secondary gear pumps. The supercharger pump is preferably activated only during high demand conditions as an additional energy conservation measure.

Abstract: A gas turbine engine fuel supply system includes a primary gear pump, a secondary gear pump, and a pump bypass valve. The primary gear pump always actively delivers fuel to the downstream fuel system, and is sized to supply 100% of the burn flow needed at a select low demand condition. The secondary gear pump is sized to make up the remainder of the flow at high demand conditions, and actively delivers fuel to the downstream fuel system only during those conditions. To supply discharge fuel pressures in excess of gear pump capability, a supercharger pump is disposed upstream of the primary and secondary gear pumps. The pump bypass valve is configured to regulate fuel pressure at the primary gear pump outlet to one of a plurality of preset differential pressures above one of a plurality of fuel load pressures and prevents reverse pressurization of the gear pumps.

Abstract: A direct metering fuel supply system includes a fuel pump, a burn flow fuel line, a servo flow fuel line, and a servo regulator. The fuel pump is adapted receive pump commands representative of a commanded fuel flow rate and is configured, in response to the pump commands, to discharge fuel at the commanded fuel flow rate. The burn flow fuel line is in fluid communication with the pump to receive a first portion of the fuel discharged therefrom. The servo flow fuel line is in fluid communication with the pump to receive a second portion of the fuel discharged therefrom. The servo regulator is mounted on the servo flow fuel line and configured to maintain fuel flow rate in the servo flow fuel line at a substantially constant fuel flow rate regardless of fuel flow rate in the burn flow fuel line.

Abstract: A system provides “fail fixed” functionality and allows a user to manually manipulate fuel flow to a gas turbine engine in the unlikely event the primary control means is unavailable. The fuel metering unit includes a fuel metering valve, a flow increase valve, and a flow decrease valve. The flow increase valve and flow decrease valves are both in fluid communication with the fuel metering valve and are each adapted to selectively receive fuel flow commands from a primary fuel flow command source and from a secondary fuel flow command source. The flow increase and decrease valves are responsive to the fuel flow commands to selectively control the position of the fuel metering valve.

Abstract: A fuel divider system includes a housing assembly and a flow passage network having an inlet, a primary outlet, and a secondary outlet. A fuel divider piston is slidably disposed within the housing assembly and movable between a flow biasing position and a flow equalizing position. A control chamber is fluidly coupled to the flow passage network and fluidly communicates with the piston. An inlet chamber, at least partially defined by the piston and the housing assembly, is fluidly coupled to the inlet. At least one channel is provided through the piston and configured to cooperate with the flow passage network to port the FD control chamber to: (i) the fuel pressure at the secondary outlet when the FD piston is in the flow biasing position, and (ii) the fuel pressure within the inlet chamber when the FD piston is in the flow equalizing position.

Abstract: A flow equalizing override assembly is provided for use in conjunction with a gas turbine engine (GTE) and a fuel divider system. In one embodiment, the flow equalizing override assembly includes a housing assembly, a fuel divider (FD) valve, a remotely-actuatable valve, and a controller. The FD valve includes: (i) a piston slidably disposed within the housing assembly and movable between a default position and a flow equalizing position, and (ii) a control chamber defined by the piston and the housing assembly. The remotely-actuatable valve is fluidly coupled to the control chamber and is configured to selectively adjust the fuel pressure therein. The controller is configured to command the remotely-actuatable valve to adjust the pressure within the control chamber such that the piston moves from the default position to the flow equalizing position after ignition of the GTE.