Abstract: A trocar coupling assembly includes a housing disposable in a tubular shaft of a surgical stapler. The housing has opposed openings defining a passage through the housing that is capable of receiving a trocar assembly therein. A release button is accessible through the tubular shaft for transitioning the trocar coupling assembly between a locked configuration and an unlocked configuration.

Abstract: Surgical instruments include a first drive assembly having a first drive gear and a lockout mechanism positioned for releasable engagement with the first drive assembly to inhibit rotation of the first drive gear. The lockout mechanism includes a pawl and an actuator for moving the pawl from a first position in engagement with the first drive gear to a second position spaced from the first drive gear.

Abstract: A surgical device includes a handle assembly having a controller and an adapter assembly including a tubular housing having a proximal end portion configured to couple to the handle assembly and a distal end portion. The adapter assembly also includes a load sensing assembly disposed with the tubular housing. The load sensing assembly is configured to measure a load exerted on the tubular housing and includes: a sensor body having a pocket defined therein; a load sensor circuit disposed within the pocket and coupled to the sensor body; and a signal processing circuit disposed within the pocket and electrically coupled to the load sensor circuit. The load sensing assembly further includes a cover disposed over the pocket and enclosing the load sensor circuit and the signal processing circuit therein, the cover being coupled to the sensor body thereby forming a first hermetic seal therebetween.

Abstract: A single-use bioreactor is provided. The single-use bioreactor may include a bioprocess container, a shell, at least one agitator, at least one sparger, at least one gas filter inlet port for the sparger(s) and headspace overlay, at least one fill port, at least one harvest port, at least one sample port, and at least one probe. In examples, at least one controller may monitor and control one or more parameters associated with the single-use bioreactor A method to cultivate and propagate mammalian cells is also provided. The method may include cultivating under suitable conditions and in a suitable culture medium in a first single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a second single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a third single-use bioreactor, and cultivating the cells in the third bioreactor.

Abstract: A device for loading a trocar assembly with an adapter assembly of a surgical stapling instrument is provided. The trocar loading device includes a base member and an engagement member operatively secured to the base member. The base member defines a longitudinal passage for receipt of a trocar assembly and the engagement member releasably secures the trocar member within the base member. The base member includes an alignment feature for aligning the trocar assembly with an adapter assembly.

Abstract: A tool assembly includes a cartridge assembly, a shell, and an anvil assembly. The shell houses the cartridge assembly and defines a passage. The shell includes alignment splines that are disposed within the passage and define channels between adjacent alignment splines. The anvil assembly includes an anvil and a center rod that extends from the anvil. The center rod defines a longitudinal axis and includes a first spline and second splines. The first spline includes a first leading facet that is configured to engage the alignment splines to clock the anvil assembly relative to the cartridge assembly. The second splines are radially spaced apart about the longitudinal axis. Each of the second splines includes a leading end that defines a plane that is substantially orthogonal to the longitudinal axis. The leading end is configured to crash with the alignments spines when the anvil assembly is misaligned with the cartridge assembly.

Abstract: A trocar assembly for releasable engagement with an adapter assembly of a surgical stapling instrument includes a trocar mechanism that includes a trocar member that is at least one of rotatable or articulable relative to a housing of the trocar assembly.

Abstract: An apparatus for ensuring strain gauge accuracy including a handle assembly including a controller, an adapter assembly including a tubular housing having a proximal end portion configured to couple to the handle assembly and a distal end portion, a load sensing assembly configured to measure a load exerted on the tubular housing, and a signal processing circuit electrically coupled to the load sensing assembly, a memory coupled to the signal processing circuit, and a calibration assembly including a biasing member having a known spring rate stored as a force value in the memory, the calibration assembly configured to couple to the distal end portion of the adapter assembly. The signal processing circuit is configured to calibrate the adapter assembly with the calibration assembly attached thereto by calculating a correction factor based on a comparison a force of the spring member measured by the load sensing assembly to the force value.

Abstract: A circular stapling device includes an anvil assembly and an adaptor assembly including a shell assembly. The adaptor assembly includes an anvil retainer including an asymmetric tip. The anvil assembly has a center rod, an anvil head supported on the center rod, and an alignment member. The center rod has a proximal portion and a distal portion and defines a channel that extends from the proximal portion to the distal portion. The alignment member is positioned within the channel and is configured to engage the asymmetric trocar tip of the anvil retainer of the adaptor when the anvil assembly is attached to the anvil retainer to properly align the anvil assembly with the shell assembly.

Abstract: An apparatus for ensuring strain gauge accuracy including a handle assembly including a controller, an adapter assembly including a tubular housing having a proximal end portion configured to couple to the handle assembly and a distal end portion, a load sensing assembly configured to measure a load exerted on the tubular housing, and a signal processing circuit electrically coupled to the load sensing assembly, a memory coupled to the signal processing circuit, and a calibration assembly including a biasing member having a known spring rate stored as a force value in the memory, the calibration assembly configured to couple to the distal end portion of the adapter assembly. The signal processing circuit is configured to calibrate the adapter assembly with the calibration assembly attached thereto by calculating a correction factor based on a comparison a force of the spring member measured by the load sensing assembly to the force value.

Abstract: The present disclosure relates to adapter assemblies for use with and to electrically and mechanically interconnect electromechanical surgical devices and surgical reloads, and to surgical systems including handheld electromechanical surgical devices and adapter assemblies for connecting surgical reloads to the handheld electromechanical surgical devices.

Abstract: The present disclosure relates to force sensors and force sensor substrates for use with surgical devices.

Abstract: A circular stapling device includes an anvil assembly and an adaptor assembly including a shell assembly. The adaptor assembly includes an anvil retainer including an asymmetric tip. The anvil assembly has a center rod, an anvil head supported on the center rod, and an alignment member. The center rod has a proximal portion and a distal portion and defines a channel that extends from the proximal portion to the distal portion. The alignment member is positioned within the channel and is configured to engage the asymmetric trocar tip of the anvil retainer of the adaptor when the anvil assembly is attached to the anvil retainer to properly align the anvil assembly with the shell assembly.

Abstract: A surgical stapling device includes reload assembly that is supported on a distal portion of an elongate shaft of the surgical stapling device. The reload includes a housing, a pusher assembly movably supported within the housing, a knife carrier movably supported within the pusher assembly, and an annular knife supported on the knife carrier. The elongate body includes a pusher drive member and a knife carrier pusher. The knife carrier includes first engagement structure that is configured to releasably engage second engagement structure formed on the knife carrier pusher to releasably couple the knife carrier pusher to the knife carrier. The knife carrier supports at least one detent that is movable into contact with a distal portion of the pusher drive member as the knife carrier is retracted to urge the first engagement structure out of engagement with the second engagement structure to uncouple the knife carrier from the knife carrier pusher.

Abstract: The present disclosure relates to force sensors and force sensor substrates for use with surgical devices.

Abstract: The present disclosure relates to adapter assemblies for use with and to electrically and mechanically interconnect electromechanical surgical devices and surgical reloads, and to surgical systems including handheld electromechanical surgical devices and adapter assemblies for connecting surgical reloads to the handheld electromechanical surgical devices.

Abstract: The present disclosure relates to adapter assemblies for use with and to electrically and mechanically interconnect electromechanical surgical devices and surgical reloads, and to surgical systems including handheld electromechanical surgical devices and adapter assemblies for connecting surgical reloads to the handheld electromechanical surgical devices.

Abstract: The present disclosure relates to adapter assemblies for use with and to electrically and mechanically interconnect electromechanical surgical devices and surgical reloads, and to surgical systems including handheld electromechanical surgical devices and adapter assemblies for connecting surgical reloads to the handheld electromechanical surgical devices.

Abstract: A surgical stapling device includes a reload assembly that includes a locking member to retain a knife carrier of the reload assembly in a retracted position after the stapling device is fired. The locking member may be supported on an inner housing portion of the shell housing or on a staple pusher assembly of the reload assembly.

Abstract: A system includes a wiring harness and an encapsulation assembly for encapsulating a connection region between electronic components of the wiring harness. The wiring harness includes a force sensor electrically coupled to a flex cable at a connection region. The encapsulation assembly includes a mold having a first and second mold halves configured to retain the force sensor therein and define a cavity above the connection region of the wiring harness.