Abstract: A cover for a container that includes a lid portion and a collar element. The lid portion having a main body section surrounded by a peripheral sealing shoulder. The collar element having a peripheral collar sealing shoulder that includes a collar groove and wherein the lid portion is connected to the collar portion through a hinge element. The lid portion, collar element and hinge portion are formed as a unitary structure and the lid portion articulates from an open positon in which it is spaced apart from the collar element to a closed position wherein the peripheral bead sealing shoulder of the lid portion engages with the peripheral collar sealing shoulder of the collar element.

Abstract: Realtime communications between communicants in a virtual area are administered. Assemblies of copresent communicants in the virtual area are detected. For each of respective ones of the detected assemblies, a respective meeting object linked to information relating to communicant interactions in the assembly is generated. Respective meeting summary data is determined based on the information linked to selected ones of the meeting objects meeting objects. The determined meeting summary data is transmitted to a network node for display. A visualization of summaries of respective assemblies of copresent communicants in the virtual area is presented on a display.

Abstract: A respiratory disease analytics system provides respiratory disease risk reports to a patient, provider, or third-party entity describing a patient's risk of experiencing a medication usage event given data in a geographic region. Regional data, including air pollutant conditions, weather conditions, demographic information, built environment factors, and regional health conditions for a geographic region are accessed from other sources and assigned based on event data recorded during a medicament usage event, as collected by sensors associated with the patient's medicament device/s. The regional data is assigned to medicament usage events occurring within a period of time. The assigned regional data is analyzed to determine an expected number of medication usage events for the geographic region occurring over the period of time.

Abstract: A system and method for providing chronic obstructive pulmonary disease (COPD) exacerbation risk notifications in real time or near-real time is described. Rescue and controller medication events are detected by sensors associated with the patient's medicament device/s, and provide a basis to determine to rescue and controller medication use trends for the patient. This data is analyzed to determine the patient's risk for COPD exacerbation after each event, and is used to send notifications to one or both of the patient and their health care provider.

Abstract: The invention relates to a system for manufacturing a plurality of integrated circuits, IC, mounted on a common support, the system comprising: an input station configured (adapted, arranged) to receive at least one common support; an output station configured (adapted, arranged) to receive at least one common support having a plurality of integrated circuits formed thereon; a plurality of processing modules each module being operable (configured, arranged, adapted) to perform at least one of the processing steps (e.g. deposition, patterning, etching) for forming an integrated circuit on the common support; a transfer means operable (configured, arranged, adapted) to transfer the at least one common support from the input station to the output station and to one or more of the processing modules therebetween; control means (e.g.

Abstract: A system and method for providing secure access to an organization's internal resources by an application running on an external network. An agent accepts queries from the application which are passed to a relay with a dynamic filter. The relay establishes a secure connection with a connector through the organization's firewall and passes requests from the application to an authentication service running on the internal network to confirm that a user of the application is authorized and issue an authentication ticket which is returned to the application. The application then sends a request to access a specific internal resource based on the authentication ticket, which is passed to a ticket granting service running on the internal network, to verify that said user is authorized to access the specific internal resource, and, if so, issue a service ticket to grant access the application for that resource.

Abstract: A wirelessly-controlled jamb-mounted access control system can include an in-jamb housing, a lock body at least partially inside the housing and rotatable about a first axis between locked and unlocked positions. The first axis can extend parallel to the jamb, and the lock body can include inner and outer sidewalls that define a latch cavity configured to receive a latch tongue of a door. The wirelessly-controlled jamb-mounted access control system can further include an actuator configured to control release of the lock body from the locked position in response to a control signal.

Abstract: A universally adaptable waffle-cavity form and methods for constructing a waffle panel are described. The waffle-cavity form is provided with a standard shape and size and can be easily adapted to alter the dimensions thereof. The form can be cut down and combined with one or more other cut down forms to provide a combined form with desired dimensions. The forms can also be combined without first being cut down through the use of a saddle that is placed over a joint therebetween. A plurality of the forms can be affixed to a mold decking in a desired arrangement using anchors installed therebetween to form a mold that is reusable to produce multiple waffle panels.

Abstract: Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders.

Abstract: Machine learning-based techniques for predicting trademark similarity are described. For instance, a first trademark pair comprising an attribute of a first trademark and a corresponding attribute of a second trademark is received. A level of similarity is determined between the first trademark pair and respective second trademark pairs included in respective legal proceedings maintained in a database. A subset of proceedings from the proceedings is selected, each proceeding of the subset including a respective second trademark pair that has the level of similarity with the first trademark pair. A feature vector is generated based on each proceeding of the subset. The feature vector is provided to a machine learning model that outputs a prediction score, based on the feature vector, as to whether a subsequent proceeding would find a likelihood of confusion between the first trademark and the second trademark. The prediction score is provided to a user interface.

Abstract: Apparatus transmits an identifier for association with a virtual area by an administering network service, generates output data from human perceptible stimulus in a physical space, transmits the output data in connection with the virtual area, receives input data associated with the virtual area, and generates human perceptible stimulus in the physical space from the input data. A persistent association is created between the apparatus and a virtual area. A respective presence is established in the virtual area for a communicant operating a client network node connected to the virtual area. A respective connection between each active pair of complementary sources and sinks of the client network node and the apparatus are administered in association with the virtual area. A client network node displays a graphical user interface, establishes the administered connections, and presents interaction controls associated with the object for interacting with communicants in the physical space.

Abstract: An ophthalmic device includes an optic including an optic axis and a closed-loop haptic structure coupled to the optic via a frame surrounding the optic, the closed-loop haptic structure including a closed loop extending from first and second attachment points to the frame. The closed loop includes a first hinge and a second hinge. The first hinge has a first section having a first component extending in a first angular direction, a second section having a second component extending in a second angular direction opposite to the first angular direction, and a first connecting section between the first section and the second section. The second hinge has a third section having a third component extending in the second angular direction, a fourth section having a fourth component extending in the first angular direction, the fourth section being connected to the second section to form the closed loop.

Abstract: A system and method for promoting and safeguarding the wellbeing of patients in relation to a fluid injection may obtain patient data; determine, based on the patient data, an initial risk prediction for a patient for a fluid injection to be administered to the patient, the initial risk prediction including a probability that the patient experiences at least one adverse event in response to the fluid injection; provide, to a user device, before the fluid injection is administered to the patient, the initial risk prediction; determine, after the fluid injection is started, sensor data associated with the patient; determine, based on the sensor data determined after the fluid injection is started, a current risk prediction including a probability that the patient experiences the at least one adverse event in response to the fluid injection; and provide, to the user device, the current risk prediction.

Abstract: This invention establishes a new paradigm for treatment of Parkinson's disease (PD) by eliminating senescent cells that reside in or around the site of the disease pathophysiology. Exposure of test subjects to the herbicide paraquat (PQ) increases the risk for developing Parkinson's disease. The data in this disclosure show that PQ induces a senescence arrest and SASP in astrocytes, in culture and in vivo in mice, and senescent cell markers were present in astrocytes in midbrain tissue from PD patients. In a transgenic mouse model, senescent cell ablation protected against PQ-induced PD-like neuropathology. Removal of senescent cells from affected sites using small molecule agents that specifically target senescent cells can help prevent or ameliorate signs and symptoms of the disease.

Abstract: The invention pertains to a process for the production of crystalline carbon structure networks in a reactor 3 which contains a reaction zone 3b and a termination zone 3c, by injecting a thermodynamically stable micro-emulsion c, comprising metal catalyst nanoparticles, into the reaction zone 3b which is at a temperature of above 600° C., preferably above 700° C., more preferably above 900° C., even more preferably above 1000° C., more preferably above 1100° C., preferably up to 3000° C., more preferably up to 2500° C., most preferably up to 2000° C., to produce crystalline carbon structure networks e, transferring these networks e to the termination zone 3c, and quenching or stopping the formation of crystalline carbon structure networks in the termination zone by spraying in water d.

Abstract: A three-dimensional discretized computer model of a part in a three-dimensional discretized design space comprising three-dimensional geometrical elements is obtained. A signed distance field based on a geometry of the three-dimensional discretized computer model of the part as represented in the three-dimensional geometrical elements of the three-dimensional discretized design space is produced. At least one non-branching cooling channel in a portion of the three-dimensional discretized design space is generated.

Abstract: In various example embodiments, a system and method for handling a replaced smart device are presented. A computer-implemented replaced device handler detects that a user's smart device was replaced with a new device of the same class and, in response, presents the user with an invitation to sell their old device that has been replaced. A replaced device handler may be provided in connection with an on-line trading platform.

Abstract: Computing device(s) are configured for managing the reunification of students with parents during an emergency or a drill for a simulated emergency. The reunification of students with guardians may be managed through the operations of various user interfaces (UIs) presented on the device(s). Different UIs may be configured to support different personnel performing different roles in the reunification process. The UIs may include one or more of a student supervisor UI, a location supervisor UI, a runner UI, a guardian greeter UI, a reunification officer UI, or an incident commander UI. The various UIs enable different personnel to track the location and status of individuals, such as students and guardians, during various stages of a reunification process, enable personnel to dynamically update a centralized database with current information regarding the location and status of individuals, and view real time information regarding the location and status of individuals.

Abstract: A realtime kernel supports realtime communications between communicants operating on respective network nodes. The realtime kernel handles the complex tasks of connecting to communicants, virtual areas, and other network resources, switching those connections in response to user inputs, and mixing realtime data streams. The realtime kernel enables developers to focus on developing high-level communications functionality instead of low-level plumbing code. The realtime kernel imposes relatively low computational resource requirements so that realtime communications performance can be achieved using a wide range of computing devices and network connections that currently are available.