Patents by Inventor David W. House

David W. House has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Electrochemical oxidation of alkyl aromatic compounds
    Patent number: 4459186
    Abstract: Aromatic ketones may be prepared by subjecting an alkyl aromatic compound containing more than one carbon atom in the alkyl substituent to an electrical energy which includes a direct electrical current in the presence of a nucleophile such as an organometallic oxide, a solvent and a reaction initiator such as an alkali metal hydroxide and a quaternary ammonium hydroxide to produce a ketal, following which the ketal may be converted to the desired ketone by hydrolysis.
    Type: Grant
    Filed: August 27, 1982
    Date of Patent: July 10, 1984
    Assignee: UOP Inc.
    Inventors: Thomas P. Malloy, Mark A. Halter, David W. House
  • Resolution of d,1-menthol
    Patent number: 4418225
    Abstract: 1-Menthol can be readily obtained from racemic menthol by conversion of the latter to the diastereomeric esters of an optically active amino acid and chromatographing the diastereomers. The separation of the diastereomeric esters is relatively insensitive to the support or to the solvent used as eluant, and satisfactory separation occurs under a broad variety of conditions. 1-Menthol can be obtained by base catalyzed hydrolysis of the purified diastereomer with high optical purity.
    Type: Grant
    Filed: January 8, 1982
    Date of Patent: November 29, 1983
    Assignee: UOP Inc.
    Inventor: David W. House
  • Resolution of racemic amino acids
    Patent number: 4379941
    Abstract: Racemic amino acids can be readily resolved by conversion to their diastereomeric esters of an optically active 2-isopropyl-5-methylcyclohexanol and separating the diastereomers by chromatography. It has been observed that the separation of the diastereomeric esters is relatively insensitive to the support or the solvent used as eluant. Thus, satisfactory separation occurs under a broad variety of conditions. The optically active amino acid can be obtained by base catalyzed hydrolysis of the purified diastereomer with high optical purity.
    Type: Grant
    Filed: January 8, 1982
    Date of Patent: April 12, 1983
    Assignee: UOP Inc.
    Inventor: David W. House
  • Electrochemical oxidation of alkyl aromatic compounds
    Patent number: 4354904
    Abstract: Aromatic aldehydes may be prepared by subjecting a methyl-substituted aromatic compound to an electrical energy which includes a direct electrical current utilizing a basic medium to form an acetal, following which the acetal may be converted to the desired aldehyde by subjecting said acetal to acid hydrolysis.
    Type: Grant
    Filed: February 13, 1981
    Date of Patent: October 19, 1982
    Assignee: UOP Inc.
    Inventors: Thomas P. Malloy, Mark A. Halter, David W. House
  • Chiral supports for resolution of racemates
    Patent number: 4324681
    Abstract: A silylated silica or alumina covalently bonded to a chiral amino acid through a carboxyl group of said acid may be used as the solid stationary phase in the chromatographic resolution of racemic mixtures. Several classes of derivatives of such bound chiral amino acids also may be used in the resolution of racemates. Such derivatives include N-alkyl and N-acyl derivatives, and esters where the amino acid is a dicarboxylic acid or contains a hydroxy group.
    Type: Grant
    Filed: June 12, 1980
    Date of Patent: April 13, 1982
    Assignee: UOP Inc.
    Inventor: David W. House
  • Chiral supports for resolution of racemates
    Patent number: 4322310
    Abstract: A composition comprising a chiral organic amine covalently linked via a carbamate, mercaptocarbamate, or urea linkage to a chain of atoms whose other terminus is covalently bound to a core support may be used as a solid phase chromatographic medium in the separation of racemic mixtures. An example is alpha-methylbenzyl amine bound through a carbamate linkage to a 3-propylsilyl group covalently bonded to an alumina support.
    Type: Grant
    Filed: June 12, 1980
    Date of Patent: March 30, 1982
    Assignee: UOP Inc.
    Inventor: David W. House