Patents by Inventor David W. Robertson

David W. Robertson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020004510
    Abstract: The present invention provides for methods for the treatment of fibromyalgia syndrome or chronic fatigue syndrome by the administration of heterocyclic amine-type compounds, substituted phenylazacycloalkane-type compounds, or cabergoline-type compounds, or a salt of any said compound.
    Type: Application
    Filed: April 17, 2001
    Publication date: January 10, 2002
    Inventors: Robert B. McCall, Robert Clyde Marshall, David W. Robertson, Thomas M. Ashley
  • Patent number: 5739146
    Abstract: The present invention provides (8.beta.)-N-substituted cyclo or bicycloalkyl-6-(substituted)-ergoline-8-carboxamides useful for occupying 5HT.sub.2 or 5HT.sub.1.sbsb.c receptors in mammals. The invention also provides methods for treating a variety of disorders and conditions related to or affecting these receptors as well as pharmaceutical formulations of the compounds of the invention.
    Type: Grant
    Filed: May 1, 1995
    Date of Patent: April 14, 1998
    Assignee: Eli Lilly and Company
    Inventors: Marlene L. Cohen, David W. Robertson
  • Patent number: 5563148
    Abstract: This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.
    Type: Grant
    Filed: April 25, 1995
    Date of Patent: October 8, 1996
    Assignee: Eli Lilly and Company
    Inventors: Marlene L. Cohen, William B. Lacefield, David W. Robertson
  • Patent number: 5554640
    Abstract: This invention provides a method of selectively antagonizing-the 5-HT.sub.1A receptor in mammals by administering aryloxypropanolamines. Aryloxypropanolamines are also claimed.
    Type: Grant
    Filed: February 8, 1995
    Date of Patent: September 10, 1996
    Assignee: Eli Lilly and Company
    Inventors: Edward E. Beedle, David W. Robertson, David T. Wong
  • Patent number: 5442078
    Abstract: This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.
    Type: Grant
    Filed: June 22, 1994
    Date of Patent: August 15, 1995
    Assignee: Eli Lilly and Company
    Inventors: Marlene L. Cohen, William B. Lacefield, David W. Robertson
  • Patent number: 5441961
    Abstract: The present invention provides (8.beta.)-N-substituted cyclo or bicycloalkyl-6-(substituted)-ergoline-8-carboxamides useful for occupying 5HT.sub.2 or 5HT.sub.1c receptors in mammals. The invention also provides methods for treating a variety of disorders and conditions related to or affecting these receptors as well as pharmaceutical formulations of the compounds of the invention.
    Type: Grant
    Filed: August 27, 1992
    Date of Patent: August 15, 1995
    Assignee: Eli Lilly and Company
    Inventors: Marlene L. Cohen, David W. Robertson
  • Patent number: 5420294
    Abstract: This invention provides a method of selectively antagonizing the 5-HT.sub.1A receptor in mammals by administering aryloxypropanolamines. Aryloxypropanolamines are also claimed.
    Type: Grant
    Filed: December 22, 1993
    Date of Patent: May 30, 1995
    Assignee: Eli Lilly and Company
    Inventors: Edward E. Beedle, David W. Robertson, David T. Wong
  • Patent number: 5364863
    Abstract: This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.
    Type: Grant
    Filed: April 26, 1993
    Date of Patent: November 15, 1994
    Assignee: Eli Lilly and Company
    Inventors: Marlene L. Cohen, William B. Lacefield, David W. Robertson
  • Patent number: 5356934
    Abstract: The present invention provides a method of employing (R)-fluoxetine to treat sleep Apnea.
    Type: Grant
    Filed: June 21, 1993
    Date of Patent: October 18, 1994
    Assignee: Eli Lilly and Company
    Inventors: David W. Robertson, David T. Wong
  • Patent number: 5281624
    Abstract: This invention provides N-alkyl-3-phenyl-3-(2-substituted phenoxy)propylamines which are useful to treat neurological disorders associated with norepinephrine imbalance.
    Type: Grant
    Filed: September 27, 1991
    Date of Patent: January 25, 1994
    Assignee: Eli Lilly and Company
    Inventors: Donald R. Gehlert, David W. Robertson, David T. Wong
  • Patent number: 5264445
    Abstract: This compound provides the compound (-)-N"-cyano-N-3-pyridyl-N'-1,2,2-trimethylpropylguanidine, its salts and pharmaceutical formulations, and its method of use for opening potassium channels in mammals.
    Type: Grant
    Filed: October 29, 1992
    Date of Patent: November 23, 1993
    Assignee: Eli Lilly and Company
    Inventors: David W. Robertson, Mitchell I. Steinberg
  • Patent number: 5250572
    Abstract: The present invention provides (R)-norfluoxetine and pharmaceutically acceptable salts thereof capable of selectively occupying 5HT.sub.1c receptors.
    Type: Grant
    Filed: April 21, 1992
    Date of Patent: October 5, 1993
    Assignee: Eli Lilly and Company
    Inventors: David W. Robertson, David T. Wong
  • Patent number: 5250571
    Abstract: The present invention provides (S)-norfluoxetine and pharmaceutically acceptable salts thereof capable of inhibiting the uptake of serotonin.
    Type: Grant
    Filed: April 21, 1992
    Date of Patent: October 5, 1993
    Assignee: Eli Lilly and Company
    Inventors: Ray W. Fuller, David Mitchell, David W. Robertson, Gregory A. Stephenson, David T. Wong
  • Patent number: 5238959
    Abstract: The present invention provides 3-(4-substitutedphenoxy)-3-phenyl propanamines capable of inhibiting the uptake of serotonin. These compounds are useful for treating many pharmacological disorders, including depression and obesity. These compounds can also be used to reduce the desire to smoke and consume alcohol.
    Type: Grant
    Filed: April 20, 1992
    Date of Patent: August 24, 1993
    Assignee: Eli Lilly and Company
    Inventors: David W. Robertson, David T. Wong
  • Patent number: 5226255
    Abstract: A mat for plant cultivation comprises upper and lower portions of non-woven fibers, substantially all of which are preferably natural, biodegradable fiber; an intermediate layer of bi-laterally stable plastic mesh, of high strength relative to the non-woven fiber layers, is structurally joined to the fiber portions, as by needling. The mat includes seed, and may include fertilizer and/or water absorbing material.A method of soil improvement comprises providing a mat having upper and lower portions of non-woven fibers, substantially all of which are natural, biodegradable fibers, with an intermediate bi-laterally stable plastic mesh layer structurally joined to the non-woven fibers. The mat is placed on the ground, such as a bare hill, for initially diminishing soil erosion by water run-off, the mat being optionally seeded after placement. The mat provided may be placed on poor soil, and after plant growth, the plants and mat may be plowed under, optionally in a repetitive cycle, to improve the soil.
    Type: Grant
    Filed: November 27, 1990
    Date of Patent: July 13, 1993
    Assignee: Grass Ventures, Ltd.
    Inventor: David W. Robertson
  • Patent number: 5141944
    Abstract: This invention provides N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxamides useful for blocking 5HT.sub.2 receptors in mammals having an excess of serotonin centrally or peripherally. The invention also provides methods for treating sexual dysfunction, hypertension, migraine, vasospasm, thrombosis, ischemia, depression, anxiety, sleep disorders and appetite disorders with a compound of the invention.
    Type: Grant
    Filed: June 24, 1991
    Date of Patent: August 25, 1992
    Assignee: Eli Lilly and Company
    Inventors: Marlene L. Cohen, David W. Robertson
  • Patent number: 5135947
    Abstract: The present invention provides 1-phenyl-3-naphthalenyloxypropanamines which are selective inhibitors of serotonin uptake.
    Type: Grant
    Filed: August 1, 1990
    Date of Patent: August 4, 1992
    Assignee: Eli Lilly and Company
    Inventors: David W. Robertson, David T. Wong, Dennis C. Thompson
  • Patent number: 5043341
    Abstract: This invention provides N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxamides useful for blocking 5HT.sub.2 receptors in mammals having an excess of serotonin centrally or peripherally. The invention also provides methods for treating sexual dysfunction, hypertension, migraine, vasospasm, thrombosis, ischemia, depression, anxiety, sleep disorders and appetite disorders with a compound of the invention.
    Type: Grant
    Filed: April 11, 1990
    Date of Patent: August 27, 1991
    Assignee: Eli Lilly and Company
    Inventors: Marlene L. Cohen, David W. Robertson
  • Patent number: 5023269
    Abstract: The present invention provides 3-aryloxy-3-substituted propanamines capable of inhibiting the uptake of serotonin and norepinephrine.
    Type: Grant
    Filed: March 27, 1990
    Date of Patent: June 11, 1991
    Assignee: Eli Lilly and Company
    Inventors: David W. Robertson, David T. Wong, Joseph H. Krushinski, Jr.
  • Patent number: 5013761
    Abstract: This invention provides a method of selectively antagonizing the 5-HT.sub.1A receptor in mammals by administering aryloxypropanolamines. Novel aryloxypropanolamines are also claimed.
    Type: Grant
    Filed: November 8, 1989
    Date of Patent: May 7, 1991
    Assignee: Eli Lilly and Company
    Inventors: Edward E. Beedle, David W. Robertson, David T. Wong