Abstract: The present disclosure generally relates to pharmaceutical corticosteroid compositions, and methods of making the same.

Abstract: A deployment device is described which comprises a support frame 12 provided with buoyancy tanks 20, the buoyancy of which is adjustable, the support frame 12 being adapted for use in carrying and/or deployment of a payload.

Abstract: The present disclosure generally relates to pharmaceutical corticosteroid compositions, and methods of making the same.

Abstract: A motion control apparatus for measuring and scanning an object. The motion control apparatus includes a base. The motion control apparatus also includes an object support assembly that is coupled to the base. The object support assembly receives the object to be scanned and measured. The motion control apparatus includes a scanner track that extends above from the base. The scanner and object are moveable about multiple axes to position to the scanner with respect to the object for viewing the object by the scanner for obtaining measurements of the object.

Abstract: The valve actuator (10) has a movable control element (12) which is typically connected to the valve to be opened/closed and a propulsion device (16) which may be a hydraulically operated piston (16) for moving the movable control element. A resilient element (22) which may be in the form of a spring arrangement has a stroke extending from a first relatively unloaded position to a second relatively loaded position and a transmission mechanism (18) is also provided, where the resilient element is loaded under the action of the propulsion device via the transmission mechanism and is configured to urge the moveable portion of the propulsion device towards the first position via the transmission mechanism when loaded. The transmission mechanism provides a gearing ratio reduction between the moveable portion of the propulsion device and the resilient element.

Abstract: A valve seat (10) for use in a valve incorporating a valve gate is disclosed, the valve seat comprising a valve seat body (12) and a biasing device (14) such as a spring (14), the biasing device being integral with the valve seat body. The biasing device and valve seat body may be welded together or may be formed in a single metal workpiece by a machining, casting or forging process. The valve gate and valve seat cooperate to form a metal-to-metal seal within the valve. At least a portion (15) of the valve seat is typically welded to at least a portion of the valve. A pipeline including at least one valve is also disclosed, as is a method of fitting a valve seat to a valve.

Abstract: A passenger vehicle comprises a passenger compartment with an interior space. An HVAC system conditions fresh air from outside the vehicle, wherein the HVAC system includes a main blower for delivering conditioned air to the interior space. An air extractor valve is fluidically coupled between the interior space and the outside, wherein the air extractor valve opens in response to a higher pressure in the interior space than an outside pressure. The air extractor valve substantially blocks air flow from the outside to the interior space. A supplemental blower is integrated with the air extractor valve for directing an exhaust flow from the interior to the outside, wherein the supplemental blower is activated as a function of the main blower. Alternatively, the supplemental blower is activated in response to a door being opened, enhancing the ability of the extractor to reduce door closing effort.

Abstract: A motion control apparatus for measuring and scanning an object. The motion control apparatus includes a base. The motion control apparatus also includes an object support assembly that is coupled to the base. The object support assembly receives the object to be scanned and measured. The motion control apparatus includes a scanner track that extends above from the base. The scanner and object are moveable about multiple axes to position to the scanner with respect to the object for viewing the object by the scanner for obtaining measurements of the object.

Abstract: A motion control apparatus for measuring and scanning an object. The motion control apparatus includes a base. The motion control apparatus also includes an object support assembly that is coupled to the base. The object support assembly receives the object to be scanned and measured. The motion control apparatus includes a scanner track that extends above from the base. The scanner and object are moveable about multiple axes to position to the scanner with respect to the object for viewing the object by the scanner for obtaining measurements of the object.

Abstract: Azithromycin has increased efficacy in treating acne and other skin conditions when administered systemically at low doses, below those previously known to produce a clinical antibiotic effect.

Abstract: A design methodology and algorithms for the computer aided design of integrated circuits having clock distribution networks. The clustering of latch distribution tree components is combined with repositioning of such components within clock sector areas. The movement and clustering of components is such that the timing constraints are preserved. The methods is described in terms of reducing and balancing the load inside each clock sector, although the techniques may also be applied to balancing load between clock sectors.

Abstract: Azithromycin, administered systemically, is an effective treatment for nodules associated with acne vulgaris.

Abstract: A motion control apparatus for measuring and scanning an object. The motion control apparatus includes a base. The motion control apparatus also includes an object support assembly that is coupled to the base. The object support assembly receives the object to be scanned and measured. The motion control apparatus includes a scanner track that extends above from the base. The scanner and object are moveable about multiple axes to position to the scanner with respect to the object for viewing the object by the scanner for obtaining measurements of the object.

Abstract: Azithromycin, administered systemically, is an effective treatment for nodules associated with acne vulgaris.

Abstract: A design methodology and algorithms for the computer aided design of integrated circuits having clock distribution networks. The clustering of latch distribution tree components is combined with repositioning of such components within clock sector areas. The movement and clustering of components is such that the timing constraints are preserved. The methods is described in terms of reducing and balancing the load inside each clock sector, although the techniques may also be applied to balancing load between clock sectors.

Abstract: Azithromycin has increased efficacy in treating acne and other skin conditions when administered systemically at low doses, below those previously known to produce a clinical antibiotic effect.

Abstract: The present invention relates to novel ABC1 polypeptides and nucleic acid molecules encoding the same. The invention also relates to recombinant vectors, host cells, and compositions comprising ABC1 polynucleotides, as well as to methods for producing ABC1 polypeptides. The invention also relates to antibodies that bind specifically to ABC1 polypeptides. In addition, the invention relates to methods for increasing cholesterol efflux as well as to methods for increasing ABC1 expression and activity. The present invention further relates to methods for identifying compounds that modulate the expression of ABC1 and methods for detecting the comparative level of ABC1 polypeptides and polynucleotides in a mammalian subject. The present invention also provides kits and compositions suitable for screening compounds to determine the ABC1 expression modulating activity of the compound, as well as kits and compositions suitable to determine whether a compound modulates ABC1-dependent cholesterol efflux.

Abstract: Azithromycin, administered systemically, is an effective treatment for nodules associated with acne vulgaris.

Abstract: The present invention relates to novel ABC1 polypeptides and nucleic acid molecules encoding the same. The invention also relates to recombinant vectors, host cells, and compositions comprising ABC1 polynucleotides, as well as to methods for producing ABC1 polypeptides. The invention also relates to antibodies that bind specifically to ABC1 polypeptides. In addition, the invention relates to methods for increasing cholesterol efflux as well as to methods for increasing ABC1 expression and activity. The present invention further relates to methods for identifying compounds that modulate the expression of ABC1 and methods for detecting the comparative level of ABC1 polypeptides and polynucleotides in a mammalian subject. The present invention also provides kits and compositions suitable for screening compounds to determine the ABC1 expression modulating activity of the compound, as well as kits and compositions suitable to determine whether a compound modulates ABC1-dependent cholesterol efflux.